Accumulation of non-steroidal anti-inflammatory drugs by gingival fibroblasts.

abstract：:The discoidin domain receptors, DDR1 and DDR2, are nonintegrin collagen receptors and tyrosine kinases. DDRs regulate cell functions, and their extracellular domains affect collagen fibrillogenesis and mineralization. Based on the collagenous nature of dentoalveolar tissues, we hypothesized that DDR1 plays an importan...

journal_title：Journal of dental research

authors： Chavez MB,Kolli TN,Tan MH,Zachariadou C,Wang C,Embree MC,Lira Dos Santos EJ,Nociti FH Jr,Wang Y,Tatakis DN,Agarwal G,Foster BL

更新日期：2019-12-01 00:00:00

abstract：:Samples of dental plaque obtained from the interproximal tooth surfaces of seven young men showed considerable variation in the prevalence and anatomic site distribution of the potentially cariogenic microorganism S mutans. Multiple application of 10% SnF2 topical solution and saline solution delivered to interproxima...

journal_title：Journal of dental research

authors： Keene HJ,Shklair IL,Mickel GJ

更新日期：1977-01-01 00:00:00

abstract：:Periodontal disease is a bacterial infection that results in inflammatory destruction of tissues that support the teeth, including connective tissue and bone. In this study, we report that transgenic mice that overexpress the 17-kDa form of IL-1alpha in the basal layer of oral mucosal epithelium develop a syndrome tha...

journal_title：Journal of dental research

authors： Dayan S,Stashenko P,Niederman R,Kupper TS

更新日期：2004-10-01 00:00:00

abstract：:Defects in the enamelin gene (ENAM) cause amelogenesis imperfecta (AI). Our objective was to identify the genetic etiology of enamel hypoplasia in a Caucasian proband. Our hypothesis was that ENAM was defective. The proband and his father have an AG insertion (g.13185_13186insAG; p.422FsX448) in ENAM previously identi...

journal_title：Journal of dental research

authors： Chan HC,Mai L,Oikonomopoulou A,Chan HL,Richardson AS,Wang SK,Simmer JP,Hu JC

更新日期：2010-07-01 00:00:00

abstract：:To determine the 'hard palate representing' area in the primary somatosensory cortex, we recorded somatosensory-evoked magnetic fields from the cortex in ten healthy volunteers, using magnetoencephalography. Following electrical stimulation of 3 sites on the hard palate (the first and third transverse palatine ridges,...

journal_title：Journal of dental research

authors： Bessho H,Shibukawa Y,Shintani M,Yajima Y,Suzuki T,Shibahara T

更新日期：2007-03-01 00:00:00

abstract：:A sintered hydroxyapatite (HAP) ceramic for use in wear studies was prepared from a commercial tricalcium phosphate. The sintered HAP had physical properties close to those of human enamel. The coefficient of friction and wear of the sintered HAP ceramic as characterized by tangential force, track width, and surface f...

journal_title：Journal of dental research

authors： Rootare HM,Powers JM,Craig RG

更新日期：1978-07-01 00:00:00

abstract：:The clearance of glucose from saliva was compared with that from spaces located in an intra-oral appliance. The spaces (N = 8) were similar in shape and size to posterior interdental spaces and could be sampled with a microsyringe without removing the appliance from the mouth. The subjects (N = 5) rinsed their mouths ...

journal_title：Journal of dental research

authors： Goulet D,Brudevold F,Tehrani A,Attarzadeh F

更新日期：1985-03-01 00:00:00

abstract：:The present study investigated a concept for additional cross-linking of dental polymers, by which resistance to wear of resin composites might be increased. Bifunctional ketones were added to monomer mixtures, which were then made light-curing and loaded with filler. The monomer mixtures were varied with respect to t...

journal_title：Journal of dental research

authors： Peutzfeldt A,Asmussen E

更新日期：1992-11-01 00:00:00

abstract：:This systematic review and meta-analysis assessed the efficacy of lasers in reducing dentin hypersensitivity (DH) as compared with placebo or no treatment. Seven electronic databases and a manual search resulted in 2,538 unique publications. After selection, 13 studies were included in the meta-analysis. A CONSORT-bas...

journal_title：Journal of dental research

authors： Sgolastra F,Petrucci A,Severino M,Gatto R,Monaco A

更新日期：2013-06-01 00:00:00

abstract：:A number of studies have been made investigating the properties of dental prosthodontic soft polymer materials. In such materials, which are used as short-term denture soft liners, the polymer component is complexed with one or more plasticizers. This lowers the glass transition temperature, Tg, of the polymer by allo...

journal_title：Journal of dental research

authors： Jones DW,Hall GC,Sutow EJ,Langman MF,Robertson KN

更新日期：1991-05-01 00:00:00

abstract：:The kinetics of subsurface demineralization of tooth sections has been studied in real-time by scanning microradiography (SMR). Demineralization was carried out: (1) with a large volume of solution buffered to pH = 4 to maintain a constant composition; and (2) in a small constant volume (approximately 3 mL), buffered ...

journal_title：Journal of dental research

authors： Gao XJ,Elliott JC,Anderson P

更新日期：1993-05-01 00:00:00

abstract：:Spontaneously occurring bacteriophage-resistant mutants of Actinomyces viscosus were isolated. The mutants exhibited altered coaggregation patterns with streptococci. From analysis of the data, it appears that a cell surface structure on A. viscosus may function both as a phage receptor and as a binding site for co-ag...

journal_title：Journal of dental research

authors： Tylenda CA,Kolenbrander PE,Delisle AL

更新日期：1983-11-01 00:00:00

abstract：:An acidified gel system was used to produce artificial caries lesions in root surfaces. Radiopaque surface layers were found with 47% of the lesions. Demineralized bodies of the lesion and mineralized zones of banding were seen in all lesions when examined by microradiography. Cementum and dentin seemed to respond to ...

journal_title：Journal of dental research

authors： Phankosol P,Ettinger RL,Hicks MJ,Wefel JS

更新日期：1985-05-01 00:00:00

abstract：:Wall-to-wall (WTW) polymerization contraction of filled and unfilled chemically and photo-initiated resins was studied in relation to the WTW distance. In an experimental set-up, the resins were bonded to two opposing disks, and the axial (WTW) displacement resulting from the polymerization shrinkage was measured cont...

journal_title：Journal of dental research

authors： Feilzer AJ,De Gee AJ,Davidson CL

更新日期：1989-01-01 00:00:00

abstract：:This study aims at modifying dual-cure composite cements by adding thio-urethane oligomers to improve mechanical properties, especially fracture toughness, and reduce polymerization stress. Thiol-functionalized oligomers were synthesized by combining 1,3-bis(1-isocyanato-1-methylethyl)benzene with trimethylol-tris-3-m...

journal_title：Journal of dental research

authors： Bacchi A,Dobson A,Ferracane JL,Consani R,Pfeifer CS

更新日期：2014-12-01 00:00:00

abstract：:Locally applied bisphosphonates may improve the fixation of metal implants in bone. However, systemic bisphosphonate treatment is associated with a risk of osteonecrosis of the jaw (ONJ). We hypothesized that local delivery of bisphosphonate from the implant surface improves the fixation of dental implants without com...

journal_title：Journal of dental research

authors： Abtahi J,Agholme F,Sandberg O,Aspenberg P

更新日期：2013-03-01 00:00:00

abstract：:In mineralizing hamster molars, the influence of several inhibitors on p-NPP-ase has been demonstrated, and compared with their effect on PPi-ase, known to belong to the same enzyme. Whereas the latter activity is much more physiological, p-NPP is a better substrate to distinguish between the effects of bivalent catio...

journal_title：Journal of dental research

authors： Wöltgens JH

更新日期：1977-10-01 00:00:00

abstract：:Mixed or parotid saliva from caries-active individuals consistently supported better growth of Streptococcus mutans (type c) than that from caries-free individuals. Electrophoretic studies revealed that certain proteins in caries-active salivas were susceptible to microbial attack, but similar proteins in caries-free ...

journal_title：Journal of dental research

authors： Cowman RA,Schaefer SJ,Fitzgerald RJ,Rosner D,Shklair IL,Walter RG

更新日期：1979-10-01 00:00:00

abstract：:For practical reasons, evaluation of topical fluoride products must depend upon clinical and laboratory assessments. While not always a good predictor of clinical efficacy by itself, fluoride uptake is the most commonly used laboratory test. A consideration of the relationship between possible anticaries mechanisms of...

journal_title：Journal of dental research

authors： Mellberg JR

更新日期：1990-02-01 00:00:00

abstract：:The goal of this study was to assess the ability of a scintillation camera method to detect areas of active bone loss due to periodontitis. Technetium 99m methylene diphosphonate was used as the bone-seeking radiopharmaceutical. Bone-seeking radiopharmaceutical uptake (BSRU) was imaged and quantified in alveolar bone ...

journal_title：Journal of dental research

authors： Reddy MS,English R,Jeffcoat MK,Tumeh SS,Williams RC

更新日期：1991-01-01 00:00:00

abstract：UNLABELLED:Excessive mechanical stress (MS) during hyperocclusion is known to result in disappearance of the alveolar hard line, enlargement of the periodontal ligament (PDL) space, and destruction of alveolar bone, leading to occlusal traumatism. We have recently reported that MS induces predominantly C-C chemokine li...

journal_title：Journal of dental research

authors： Tsutsumi T,Kajiya H,Goto KT,Takahashi Y,Okabe K

更新日期：2013-01-01 00:00:00

abstract：:Teas varying in fluoride and tannin concentration were evaluated in rats for anticariogenic activity. There was a direct correlation between fluoride in tea and the inhibition of sulcal caries in rats, whereas no relationship was observed between tannin and this type of lesion. Teas also had a significant effect on ca...

journal_title：Journal of dental research

authors： Rosen S,Elvin-Lewis M,Beck FM,Beck EX

更新日期：1984-05-01 00:00:00

abstract：:Indigenous populations around the world experience a disproportionate burden in terms of oral diseases and conditions. These inequalities are likely due to a complex web of social determinants that includes poverty, historical consequences of colonialism, social exclusion, government policies of assimilation, cultural...

journal_title：Journal of dental research

authors： Tiwari T,Jamieson L,Broughton J,Lawrence HP,Batliner TS,Arantes R,Albino J

更新日期：2018-07-01 00:00:00

abstract：:Cultures of Streptococcus mutans MFe28 (serotype h) were grown with differing extracellular polysaccharide (EPS) content. Biochemical and physicochemical characteristics considered relevant to caries were measured. Acid production parameters measured in a pH-stat were: Vm = 0.76 +/- 0.14 mumol/g/sec (wet weight); appa...

journal_title：Journal of dental research

authors： Dibdin GH,Shellis RP

更新日期：1988-06-01 00:00:00

abstract：:Sealants are highly effective in preventing dental caries in the pits and fissures of teeth when applied by trained operators in clinical trials and public health programs. The effectiveness of fissure sealants when applied in dental practices is still not known. The purpose of this longitudinal study was to evaluate ...

journal_title：Journal of dental research

authors： Ismail AI,Gagnon P

更新日期：1995-09-01 00:00:00

abstract：:The acute effects of smokeless tobacco (ST) on buccal mucosal transport and barrier function were studied by means of in vivo and in vitro techniques. In humans, in vivo exposure to 0.5 g ST transiently increased the transmural electrical potential difference (PD). However, despite continued exposure, PD returned to b...

journal_title：Journal of dental research

authors： Tobey NA,Schreiner VJ,Readling RD,Orlando RC

更新日期：1988-11-01 00:00:00

abstract：:Vietnamese immigrant and Norwegian children, matched according to caries experience, age, and sex, were compared with respect to S. mutans in dental plaque and in saliva. Regardless of ethnic group, S. mutans prevalence was highest in plaque over caries lesions and from fissures, and lowest in plaque from smooth surfa...

journal_title：Journal of dental research

authors： Scheie AA,Selikowitz HS,Arneberg P

更新日期：1984-12-01 00:00:00

abstract：:The cariostatic benefit from water fluoridation is indisputable, but the knowledge of possible adverse effects on bone and fracture risk due to fluoride exposure is ambiguous. The association between long-term (chronic) drinking water fluoride exposure and hip fracture (ICD-7-9: '820' and ICD-10: 'S72.0-S72.2') was as...

journal_title：Journal of dental research

authors： Näsman P,Ekstrand J,Granath F,Ekbom A,Fored CM

更新日期：2013-11-01 00:00:00

abstract：:Overgrowth of oral yeast is a common problem among the elderly. Probiotic bacteria are known to inhibit the growth of pathogenic microbes. We tested the hypothesis that cheese containing probiotic bacteria can reduce the prevalence of oral Candida. During this 16-week, randomized, double-blind, placebo-controlled stud...

journal_title：Journal of dental research

authors： Hatakka K,Ahola AJ,Yli-Knuuttila H,Richardson M,Poussa T,Meurman JH,Korpela R

更新日期：2007-02-01 00:00:00

abstract：:Ten dental casting alloys were tested for alloy-element release into cell-culture medium, and this release was related to alloy composition, alloy microstructure, and alloy cytotoxicity (previously determined). Cell-culture medium was analyzed for alloy elements by flame atomic absorption. Concentrations of elements i...

journal_title：Journal of dental research

authors： Wataha JC,Craig RG,Hanks CT

更新日期：1991-06-01 00:00:00