Hyperocclusion up-regulates CCL3 expression in CCL2- and CCR2-deficient mice.

abstract：:Mixtures containing two bacterial species were analyzed using flow cytometric techniques. Light scattering characteristics of Streptococcus mutans and Actinomyces viscosus show unique profiles for pure cultures. However, the light scatter analysis of a mixture containing these two species demonstrates overlapping near...

journal_title：Journal of dental research

authors： Barnett JM,Cuchens MA,Buchanan W

更新日期：1984-08-01 00:00:00

abstract：:Although little is known about the mechanism of action of eugenol, some related compounds have been compared with capsaicin derivatives in terms of the relationship between their chemical structure and activity. To elucidate whether eugenol and capsaicin act via a common mechanism at the neuronal membrane, we investig...

journal_title：Journal of dental research

authors： Ohkubo T,Kitamura K

更新日期：1997-11-01 00:00:00

abstract：:The study of biofilm structure and function mandates the use of model systems for which a host of environmental variables can be rigorously controlled. We describe a model of supragingival plaque containing Actinomyces naeslundii, Veillonella dispar, Fusobacterium nucleatum, Streptococcus sobrinus, and Streptococcus o...

journal_title：Journal of dental research

authors： Guggenheim B,Giertsen E,Schüpbach P,Shapiro S

更新日期：2001-01-01 00:00:00

abstract：:The efficacy of a new remineralization system was determined in vivo by maintaining a low concentration of approximately 1 ppm fluoride for 48 hrs against a demineralized human tooth. Human subjects were selected who wore removable partial dentures containing two or more of the demineralized teeth with film system. Th...

journal_title：Journal of dental research

authors： Abrahams LJ,Yonese M,Higuchi WI,Fox JL,Charbeneau GT

更新日期：1980-03-01 00:00:00

abstract：:Odontoblasts and fibroblasts are suspected to influence the innate immune response triggered in the dental pulp by micro-organisms that progressively invade the human tooth during the caries process. To determine whether they differ in their responses to oral pathogens, we performed a systematic comparative analysis o...

journal_title：Journal of dental research

authors： Staquet MJ,Durand SH,Colomb E,Roméas A,Vincent C,Bleicher F,Lebecque S,Farges JC

更新日期：2008-03-01 00:00:00

abstract：:The discovery and implementation of fluoride in the prevention of dental caries is often praised as one of the most important achievements in health care. In the early 20th century, it took 30 y to identify fluoride as the cause of enamel mottling but also of reduced caries prevalence in a population drinking water co...

journal_title：Journal of dental research

authors： Ten Cate JM,Buzalaf MAR

更新日期：2019-07-01 00:00:00

abstract：:PAX9 is a transcription factor expressed in the tooth mesenchyme during tooth morphogenesis. In Pax9-null mice, tooth development is arrested at the bud stage. In humans, heterozygous mutations in PAX9 have been associated with non-syndromic tooth agenesis, predominantly in the molars. Here, we report 2 novel mutation...

journal_title：Journal of dental research

authors： Mitsui SN,Yasue A,Masuda K,Watanabe K,Horiuchi S,Imoto I,Tanaka E

更新日期：2014-03-01 00:00:00

abstract：:The pathomechanics of degenerative joint disease of the temporomandibular joint (TMJ) may involve fatigue produced by mechanical work on the articulating tissues. This study tested the hypotheses that mechanical work in the TMJ (i) varies with the type of mandibular activity, and (ii) is evenly distributed over TMJ su...

journal_title：Journal of dental research

authors： Gallo LM,Chiaravalloti G,Iwasaki LR,Nickel JC,Palla S

更新日期：2006-11-01 00:00:00

abstract：:Recent functional animal studies have reported that the motor control of masticatory muscle function is bilaterally guided by both hemispheres, which may fundamentally differ from the cortical control of limb muscle function. In this study, we investigated whether unilateral cortical brain infarction induces different...

journal_title：Journal of dental research

authors： Kemppainen P,Waltimo A,Palomäki H,Salonen O,Könönen M,Kaste M

更新日期：1999-12-01 00:00:00

abstract：:The junctional epithelium (JE) is unique with regard to its wide intercellular spaces and sparsely developed intercellular junctions. Thus, knowledge of the molecular mechanisms that regulate the formation of the intercellular junctions of the junctional epithelium may be essential to understand the pathophysiology of...

journal_title：Journal of dental research

authors： Lee G,Kim HJ,Kim HM

更新日期：2016-03-01 00:00:00

abstract：:Growing evidence suggests that individual genetic susceptibility may influence the host's response to infections. The aim of this project was to study whether gene polymorphisms of inflammatory markers are associated with the presence of viable periodontopathogenic bacteria. We extracted genomic DNA from 45 young adul...

journal_title：Journal of dental research

authors： Nibali L,Ready DR,Parkar M,Brett PM,Wilson M,Tonetti MS,Griffiths GS

更新日期：2007-05-01 00:00:00

abstract：:Bilateral resections of the superficial masseter, posterior temporal, and anterior digastric muscles of rats were done to determine their effects on mandibular growth. The macroscopic findings support the functional matrix theory of mandibular growth. The analysis of body weight and the statistical two-way analysis of...

journal_title：Journal of dental research

authors： Lifshitz J

更新日期：1976-09-01 00:00:00

abstract：:Recent studies have shown that the extent of hydrolysis by plaque of the trypsin substrate, N-benzoyl-DL-arginine-2-naphthylamide (BANA), correlates with the numbers and proportions of spirochetes in subgingival plaque samples, and appears to be an indicator of clinical disease. In this study, BANA hydrolysis by subgi...

journal_title：Journal of dental research

authors： Schmidt EF,Bretz WA,Hutchinson RA,Loesche WJ

更新日期：1988-12-01 00:00:00

abstract：:Extracellular microcapsules have been demonstrated on cells of most serotypes of Streptococcus mutans by electron microscopy, using bacterial strains of the various serotypes and peroxidase labeled or unlabeled immune serum. A correlation was noted between the amount of capsular substance on the strains of S mutans ex...

journal_title：Journal of dental research

authors： Grenier EM,Gray RH,Loesche WJ,Eveland WC

更新日期：1977-02-01 00:00:00

abstract：:Adhesives cured under constrained conditions develop contraction stresses. We hypothesized that, with dentin as a bonding substrate, the stress would reach a maximum, followed by a continuous decline. Stress development was determined with a tensilometer for two total-etch systems and two systems with self-etching pri...

journal_title：Journal of dental research

authors： Hashimoto M,de Gee AJ,Kaga M,Feilzer AJ

更新日期：2006-08-01 00:00:00

abstract：:The inhibitory activity of 2-phosphono-butane 1,2,4 tricarboxylic acid (PBTA) in the formation of hydroxyapatite (HA) was studied in vitro and in vivo. PBTA, at 4 ppm, inhibited the spontaneous formation of HA in vitro from a supersaturated solution. PBTA, at 2 ppm, completely inhibited the crystal growth of HA; at lo...

journal_title：Journal of dental research

authors： Gaffar A,Moreno EC

更新日期：1985-01-01 00:00:00

abstract：:The anticaries effect of professional fluoride (F) application has been attributed to calcium-fluoride-like deposits (CaF(2)) formed on enamel, but this has not been clearly demonstrated. We hypothesized that CaF(2) formed on plaque-free enamel by F application would reduce enamel demineralization due to the increase ...

journal_title：Journal of dental research

authors： Tenuta LM,Cerezetti RV,Del Bel Cury AA,Tabchoury CP,Cury JA

更新日期：2008-11-01 00:00:00

abstract：:Adenosine has various biological effects on human gingival fibroblasts (HGF) and epithelial cells closely associated with inflammation, such as cytokine production and cell adhesion. However, the mechanism of adenosine formation in periodontal tissues is not yet defined. In this study, we examined the involvement of C...

journal_title：Journal of dental research

authors： Hashikawa T,Takedachi M,Terakura M,Saho T,Yamada S,Thompson LF,Shimabukuro Y,Murakami S

更新日期：2003-11-01 00:00:00

abstract：:Although proanthocyanidins (PACs) modify dentin, the effectiveness of different PAC sources and the correlation with their specific chemical composition are still unknown. This study describes the chemical profiling of natural PAC-rich extracts from 7 plants using ultra high pressure/performance liquid chromatography ...

journal_title：Journal of dental research

authors： Aguiar TR,Vidal CM,Phansalkar RS,Todorova I,Napolitano JG,McAlpine JB,Chen SN,Pauli GF,Bedran-Russo AK

更新日期：2014-04-01 00:00:00

abstract：:Zirconia-based restorations often fracture from chipping and/or delamination of the porcelain veneers. We hypothesized that veneer chipping/delamination is a result of the propagation of near-contact-induced partial cone cracks on the occlusal surface under mastication. Masticatory loading involves the opposing tooth ...

journal_title：Journal of dental research

authors： Kim JW,Kim JH,Janal MN,Zhang Y

更新日期：2008-12-01 00:00:00

abstract：:Diet is recognized as one of the most important factors affecting the equilibrium of the oral bacterial flora. Studies related to dental caries development have focused mainly on the effect of carbohydrates. In the present work, using swabbing coupled with an immuno-colony-blot assay, we followed the indigenous oral b...

journal_title：Journal of dental research

authors： Blais JF,Lavoie MC

更新日期：1990-03-01 00:00:00

abstract：:Previous studies of tooth size in twins and their families have suggested a high degree of genetic control, although there have been difficulties separating the various genetic and environmental effects. A genetic analysis of variation in crown size of the permanent incisors of South Australian twins was carried out, ...

journal_title：Journal of dental research

authors： Dempsey PJ,Townsend GC,Martin NG,Neale MC

更新日期：1995-07-01 00:00:00

abstract：:The fatigue crack growth resistance of dentin was characterized as a function of depth from the dentino-enamel junction. Compact tension (CT) specimens were prepared from the crowns of third molars in the deep, middle, and peripheral dentin. The microstructure was quantified in terms of the average tubule dimensions a...

journal_title：Journal of dental research

authors： Ivancik J,Neerchal NK,Romberg E,Arola D

更新日期：2011-08-01 00:00:00

abstract：:Information on the time-dependent release of fluoride from filled resins containing fluoride particles as a function of particle content and solution pH is limited. This study characterized the fluoride ion release from filled resins containing CaF2 particles as a function of filler content and pH. Urethane dimethacry...

journal_title：Journal of dental research

authors： Anusavice KJ,Zhang NZ,Shen C

更新日期：2005-05-01 00:00:00

abstract：:When one uses composite resins, the curing contraction, the stiffness of the material, and the strength of the vulnerable dentinal bond are important factors in determining the marginal adaptation of the restoration. Calculations based on these intrinsic material properties have indicated that both bulk placement and ...

journal_title：Journal of dental research

authors： Kemp-Scholte CM,Davidson CL

更新日期：1988-05-01 00:00:00

abstract：:Previous studies have shown that therapeutic pulsed ultrasound (pulsed) has superior stimulatory effect on bone fracture healing compared with continuous ultrasound (continuous). Our predictive hypothesis was that pulsed ultrasound can produce better bone formation during mandibular osteodistraction than continuous ul...

journal_title：Journal of dental research

authors： El-Bialy TH,Elgazzar RF,Megahed EE,Royston TJ

更新日期：2008-10-01 00:00:00

abstract：:The purpose of this study was to determine the role of saliva-derived biomarkers and periodontal pathogens during periodontal disease progression (PDP). One hundred human participants were recruited into a 12-month investigation. They were seen bi-monthly for saliva and clinical measures and bi-annually for subtractio...

journal_title：Journal of dental research

authors： Kinney JS,Morelli T,Braun T,Ramseier CA,Herr AE,Sugai JV,Shelburne CE,Rayburn LA,Singh AK,Giannobile WV

更新日期：2011-06-01 00:00:00

abstract：:Gingiva from alloxan and streptozotocin-diabetic rats exhibited markedly enhanced collagenolytic activity in tissue culture. This effect was eliminated by puromycin or by repeated freeze-thawing of the tissue prior to incubation. Soluble extracts of the diabetic gingiva in situ were found to contain breakdown products...

journal_title：Journal of dental research

authors： Golub LM,Schneir M,Ramamurthy NS

更新日期：1978-03-01 00:00:00

abstract：:The present study was conducted to investigate the role of proteolysis by matrix metalloproteinase 20 (MMP20) in regulating the initial formation of the enamel mineral structure during the secretory stage of amelogenesis, utilizing Mmp20-null mice that lack this essential protease. Ultrathin sagittal sections of maxil...

journal_title：Journal of dental research

authors： Yamazaki H,Tran B,Beniash E,Kwak SY,Margolis HC

更新日期：2019-04-01 00:00:00

abstract：:Macrophage colony-stimulating factor (CSF-1) is a key regulatory cytokine for amelogenesis, and ameloblasts synthesize CSF-1. We hypothesized that PDGF stimulates DNA synthesis and regulates CSF-1 in these cells. We determined the effect of PDGF on CSF-1 expression using MEOE-3M ameloblasts as a model. By RT-PCR, MEOE...

journal_title：Journal of dental research

authors： Wittrant Y,Bhandari BS,Abboud H,Benson N,Woodruff K,MacDougall M,Abboud-Werner S

更新日期：2008-01-01 00:00:00