PDGF up-regulates CSF-1 gene transcription in ameloblast-like cells.

abstract：:Resin composites must be improved if they are to overcome the high failure rates in large stress-bearing posterior restorations. This study aimed to improve wear resistance via nano-silica-fused whiskers. It was hypothesized that nano-silica-fused whiskers would significantly improve composite mechanical properties an...

journal_title：Journal of dental research

authors： Xu HH,Quinn JB,Giuseppetti AA

更新日期：2004-12-01 00:00:00

abstract：:In mineralizing hamster molars, the influence of several inhibitors on p-NPP-ase has been demonstrated, and compared with their effect on PPi-ase, known to belong to the same enzyme. Whereas the latter activity is much more physiological, p-NPP is a better substrate to distinguish between the effects of bivalent catio...

journal_title：Journal of dental research

authors： Wöltgens JH

更新日期：1977-10-01 00:00:00

abstract：:Cell therapies utilizing mesenchymal stem cells (MSCs) could overcome limitations of traditional treatments for reconstructing craniofacial tissues. This large-scale study explored a standardized methodology for the isolation and clinical-scale expansion of alveolar bone marrow-derived MSCs (aBMSCs). We harvested 103 ...

journal_title：Journal of dental research

authors： Mason S,Tarle SA,Osibin W,Kinfu Y,Kaigler D

更新日期：2014-01-01 00:00:00

abstract：:Amylase activity in various tissues--i.e., submandibular/sublingual and parotid glands, the pancreas, saliva, and serum--in rats was measured after injection of isoproterenol, pilocarpine, and acetylcholine. All agents reduced amylase activity in the parotid gland and increased the enzyme activity in the submandibular...

journal_title：Journal of dental research

authors： Ikeno T,Nasu J,Kuzuya H

更新日期：1983-01-01 00:00:00

abstract：:Autoimmune responses to heat-shock protein 60 (HSP60) contribute to the progression of atherosclerosis, whereas immunization with HSP60 may induce atheroprotective responses. We assessed the capacity of an atheroprotective vaccine that targeted a recombinant HSP60 from Porphyromonas gingivalis (rGroEL) to induce a pro...

journal_title：Journal of dental research

authors： Hagiwara M,Kurita-Ochiai T,Kobayashi R,Hashizume-Takizawa T,Yamazaki K,Yamamoto M

更新日期：2014-04-01 00:00:00

abstract：:Focusing public insurance programs on interceptive orthodontics (IO) may increase access for low-income children. This report presents outcomes from a randomized clinical trial (RCT) comparing IO with comprehensive orthodontics (CO) in Medicaid patients. One hundred seventy pre-adolescents with Medicaid-eligible maloc...

journal_title：Journal of dental research

authors： King GJ,Spiekerman CF,Greenlee GM,Huang GJ

更新日期：2012-07-01 00:00:00

abstract：:The cacao bean husk has been shown to possess two types of cariostatic substances, one showing anti-glucosyltransferase (GTF) activity and the other antibacterial activity, and to inhibit experimental dental caries in rats infected with mutans streptococci. In the present study, chromatographic purification revealed h...

journal_title：Journal of dental research

authors： Osawa K,Miyazaki K,Shimura S,Okuda J,Matsumoto M,Ooshima T

更新日期：2001-11-01 00:00:00

abstract：:A major extracellular protein of cultured adult human gingival fibroblasts was shown to be fibronectin by indirect immunofluorescence, lactoperoxidase catalyzed iodination and metabolic radiolabeling. Fibronectin preparations from these cells possessed the biological properties of agglutination of sheep red blood cell...

journal_title：Journal of dental research

authors： Baum BJ,Wright WE

更新日期：1980-03-01 00:00:00

abstract：:Previous studies have indicated that tooth-bleaching agents contain potentially hazardous chemicals. The present study evaluates the acute toxicity of a commercially available tooth-bleaching agent and carbamide peroxide, which is the active bleaching ingredient. Rats were dosed by stomach gavage, i.e., via a stomach ...

journal_title：Journal of dental research

authors： Dahl JE,Becher R

更新日期：1995-02-01 00:00:00

abstract：:The bactericidal effect of hexylresorcinol was assessed using bacterial aggregates. Increased drug concentration resulted in decreased survival of bacteria when the aggregates were exposed to hexylresorcinol for at least eight hours. This indicates that this drug may be effective against dental plaque only when availa...

journal_title：Journal of dental research

authors： Kraal JH,Hussain AA,Gregorio SB,Akaho E

更新日期：1979-11-01 00:00:00

abstract：:Improved mechanical properties of resin composites have been reported to be a consequence of the addition of aldehyde to the resins. The objective of the present study was to examine whether this improvement could be attributed to an increased degree of conversion of double bonds. For this purpose, propanal was added ...

journal_title：Journal of dental research

authors： Peutzfeldt A

更新日期：1994-10-01 00:00:00

abstract：:Although the tripeptides Glu-O-Phosphoserine-Tyr and Glu-O-Phosphoserine-Leu have been identified in embryonic bovine enamel proteins, 1, 2 the issue of whether both sequences occur in each of the phosphopeptides, or whether certain sequences occur in specific peptides only, has recently been resolved by isolating hom...

journal_title：Journal of dental research

authors： Glimcher MJ

更新日期：1979-03-01 00:00:00

abstract：:Locally applied bisphosphonates may improve the fixation of metal implants in bone. However, systemic bisphosphonate treatment is associated with a risk of osteonecrosis of the jaw (ONJ). We hypothesized that local delivery of bisphosphonate from the implant surface improves the fixation of dental implants without com...

journal_title：Journal of dental research

authors： Abtahi J,Agholme F,Sandberg O,Aspenberg P

更新日期：2013-03-01 00:00:00

abstract：:This paper aims to present a simple overview of potential new diagnostic methods for dental caries. There are several novel methods of caries detection (with potential application to diagnosis) which have been proposed in the last few years, in addition to those that are gaining some commercial exposure and clinical a...

journal_title：Journal of dental research

authors： Hall A,Girkin JM

更新日期：2004-01-01 00:00:00

abstract：:The aims of this work were (a) to assess the oral bioavailability of fluoride delivered from dentifrices and (b) to test for a possible link between the results and clinical data obtained with the same dentifrices. Oral fluoride concentrations were measured in samples of saliva and plaque taken from seven subjects, af...

journal_title：Journal of dental research

authors： Duckworth RM,Morgan SN,Gilbert RJ

更新日期：1992-04-01 00:00:00

abstract：:Before the 1960s, tooth-specific caries risk was reported to be highest at 2 to 4 years after eruption. We studied the tooth-specific caries risk in three contemporary age cohorts in Finland. All together, 4072 boys and girls were followed annually from age 6 to age 18+ years in three age cohorts born in the 1960s, 19...

journal_title：Journal of dental research

authors： Härkäne T,Larmas MA,Virtanen JI,Arjas E

更新日期：2002-02-01 00:00:00

abstract：:The effect of pH on the growth and proteolytic activity of the type strain and fresh isolates of Porphyromonas gingivalis and Bacteroides intermedius was investigated. B. intermedius strains grew with and without glucose at a pH as low as 5.0. These bacteria grew almost as well as Streptococcus mutans at pH 5.0 and be...

journal_title：Journal of dental research

authors： Takahashi N,Schachtele CF

更新日期：1990-06-01 00:00:00

abstract：:One-step incomplete excavation seals caries-affected dentin under a restoration and appears to be advantageous in the treatment of deep lesions. However, it is impossible to discriminate radiographically between intentionally left, arrested lesions and overlooked or active lesions. This diagnostic uncertainty decrease...

journal_title：Journal of dental research

authors： Schwendicke F,Meyer-Lueckel H,Schulz M,Dörfer CE,Paris S

更新日期：2014-06-01 00:00:00

abstract：:Auto-degradation of collagen matrices occurs within hybrid layers created by contemporary dentin bonding systems, by the slow action of host-derived matrix metalloproteinases (MMPs). This study tested the null hypothesis that there are no differences in the activities of MMP-2 and -9 after treatment with different etc...

journal_title：Journal of dental research

authors： Mazzoni A,Scaffa P,Carrilho M,Tjäderhane L,Di Lenarda R,Polimeni A,Tezvergil-Mutluay A,Tay FR,Pashley DH,Breschi L

更新日期：2013-01-01 00:00:00

abstract：:In the past two decades, accumulated evidence has clearly demonstrated the inhibitory effects of laser irradiation on enamel demineralization, but the exact mechanisms of these effects remain unclear. The purpose of this study was to investigate the effects of low-energy CO2 laser irradiation on demineralization of bo...

journal_title：Journal of dental research

authors： Hsu CY,Jordan TH,Dederich DN,Wefel JS

更新日期：2000-09-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) plays a crucial role in the modulation of orofacial pain, and we hypothesized that CGRP mediated a neuron-glia crosstalk in orofacial pain. The objective of this study was to elucidate the mechanisms whereby CGRP mediated trigeminal neuron-glia crosstalk in modulating orofacial p...

journal_title：Journal of dental research

authors： Liang H,Hu H,Shan D,Lyu J,Yan X,Wang Y,Jian F,Li X,Lai W,Long H

更新日期：2021-01-01 00:00:00

abstract：:Enamel fluorosis can occur following either an acute or chronic exposure to fluoride during tooth formation. Fluorosed enamel is characterized by a retention of amelogenins in the early-maturation stage, and by the formation of a more porous enamel with a subsurface hypomineralization. The mechanisms by which fluoride...

journal_title：Journal of dental research

authors： DenBesten PK,Thariani H

更新日期：1992-05-01 00:00:00

abstract：:An acidified gel system was used to produce artificial caries lesions in root surfaces. Radiopaque surface layers were found with 47% of the lesions. Demineralized bodies of the lesion and mineralized zones of banding were seen in all lesions when examined by microradiography. Cementum and dentin seemed to respond to ...

journal_title：Journal of dental research

authors： Phankosol P,Ettinger RL,Hicks MJ,Wefel JS

更新日期：1985-05-01 00:00:00

abstract：:Stable fluoride-resistant mutants of Streptococcus mutans GS-5 were isolated on Todd-Hewitt agar by a step-wise selection procedure. Resistance is defined here as the ability to form colonies in 48 hr. First-step mutants demonstrated six different levels of resistance, ranging from 400 to 1000 micrograms/mL sodium flu...

journal_title：Journal of dental research

authors： Brussock SM,Kral TA

更新日期：1987-10-01 00:00:00

abstract：:When one uses composite resins, the curing contraction, the stiffness of the material, and the strength of the vulnerable dentinal bond are important factors in determining the marginal adaptation of the restoration. Calculations based on these intrinsic material properties have indicated that both bulk placement and ...

journal_title：Journal of dental research

authors： Kemp-Scholte CM,Davidson CL

更新日期：1988-05-01 00:00:00

abstract：:The experiment was designed to determine the pathway taken to the brain stem by periodontal afferents responsible for the digastric jaw-opening reflex induced by tooth-tapping. Cutting the trigeminal sensory roots of anesthetized decerebrate cats eliminated the ipsilateral periodontally-induced reflex, although the st...

journal_title：Journal of dental research

authors： Collier TG,Lund JP

更新日期：1987-10-01 00:00:00

abstract：:The oral microbiome is one of the most stable ecosystems in the body and yet the reasons for this are still unclear. As well as being stable, it is also highly diverse which can be ascribed to the variety of niches available in the mouth. Previous studies have focused on the microflora in disease-either caries or peri...

journal_title：Journal of dental research

authors： Carpenter GH

更新日期：2020-06-01 00:00:00

abstract：:Several studies indicated that serotype/biotype c strains are the most common on a global basis, but that regional differences may occur relative to other serotype/biotypes. Of particular interest is the observation that individuals residing in the Middle East have higher incidences of serotype e and d strains relativ...

journal_title：Journal of dental research

authors： Farghaly MM,Eklund S,Loesche WJ

更新日期：1984-01-01 00:00:00

abstract：:The aim of this study was to investigate the diffusion dynamics of 25% hydrogen peroxide (H2O2) through enamel-dentin layers and to correlate it with dentin's structural alterations. Micro-Raman Spectroscopy (MRS) and Fourier Transform Infrared Photoacoustic Spectroscopy (FTIR-PAS) were used to measure the spectra of ...

journal_title：Journal of dental research

authors： Ubaldini AL,Baesso ML,Medina Neto A,Sato F,Bento AC,Pascotto RC

更新日期：2013-07-01 00:00:00

abstract：:Changes in stimulated and non-stimulated whole saliva flow rates were measured in 11 Hodgkin's disease patients who received therapeutic doses of radiation to a mantle field at the M. D. Anderson Hospital in Houston, Texas. Salivary flow rates were examined before, during, and after radiotherapy. Mean flow rate reduct...

journal_title：Journal of dental research

authors： Bucher JA,Fleming TJ,Fuller LM,Keene HJ

更新日期：1988-02-01 00:00:00