Demonstration of fibronectin as a major extracellular protein of human gingival fibroblasts.

abstract：:The treatment of periodontitis/peri-implantitis involves the reduction/eradication of periopathogens. After therapy, beneficial and pathogenic species recolonize the subgingival area. The dynamics of recolonization and especially the role of the supragingival environment in this process are still not well-understood. ...

journal_title：Journal of dental research

authors： Quirynen M,Vogels R,Pauwels M,Haffajee AD,Socransky SS,Uzel NG,van Steenberghe D

更新日期：2005-04-01 00:00:00

abstract：:The eventual outcome of dental caries is determined by the dynamic balance between pathological factors that lead to demineralization and protective factors that lead to remineralization. Pathological factors include acidogenic bacteria, inhibition of salivary function, and frequency of ingestion of fermentable carboh...

journal_title：Journal of dental research

authors： Featherstone JD

更新日期：2004-01-01 00:00:00

abstract：:Two copper-free amalgams expanded excessively after storage in air at 60 degrees C for about five yr. One expanded significantly at 37 degrees C and slightly at 23 degrees C. High silver content, absence of copper, and presence of small amounts of zinc, or all three, seemed to promote very high expansions at 60 degree...

journal_title：Journal of dental research

authors： Paffenbarger GC,Rupp NW,Patel PR

更新日期：1982-06-01 00:00:00

abstract：:Previous reports have linked the prevalence of tooth abnormalities with high caries experience in the different types of epidermolysis bullosa (EB). However, it is not known to what extent the apparent susceptibility to enamel caries is due to disease-related altered enamel chemistry in these cases. The aim of this st...

journal_title：Journal of dental research

authors： Kirkham J,Robinson C,Strafford SM,Shore RC,Bonass WA,Brookes SJ,Wright JT

更新日期：1996-09-01 00:00:00

abstract：:Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large...

journal_title：Journal of dental research

authors： Yamada S,Ozaki N,Tsushima K,Yamaba S,Fujihara C,Awata T,Sakashita H,Kajikawa T,Kitagaki J,Yamashita M,Yanagita M,Murakami S

更新日期：2016-08-01 00:00:00

abstract：:Evidence from epidemiologic studies suggests that periodontal infections are independently associated with subclinical and clinical atherosclerotic vascular disease. Although the strength of the reported associations is modest, the consistency of the data across diverse populations and a variety of exposure and outcom...

journal_title：Journal of dental research

authors： Kebschull M,Demmer RT,Papapanou PN

更新日期：2010-09-01 00:00:00

abstract：:Adhesion of restorative and protective materials to dentin is an important requirement for operative and preventive dentistry. Wettability and roughness are dentin substrate conditions that are critical to establishing good adhesion. This study examined superficial and deep dentin for variations in water contact angle...

journal_title：Journal of dental research

authors： Rosales JI,Marshall GW,Marshall SJ,Watanabe LG,Toledano M,Cabrerizo MA,Osorio R

更新日期：1999-09-01 00:00:00

abstract：:MMP-20 (enamelysin), the matrix metalloproteinase family member discovered in the enamel organ, has also been detected in odontoblasts during dentin formation. We studied the presence and localization of MMP-20 in mature human teeth in health and disease. In immunohistochemistry, MMP-20-positive staining was observed ...

journal_title：Journal of dental research

authors： Sulkala M,Larmas M,Sorsa T,Salo T,Tjäderhane L

更新日期：2002-09-01 00:00:00

abstract：:In an attempt to determine the degree of co-activation present in selected cervical muscles during clenching, we instructed 12 male subjects to produce four brief maximum voluntary contraction (MVC) efforts (clenching) in a position of maximum intercuspation. Surface EMG activity was recorded bilaterally from the mass...

journal_title：Journal of dental research

authors： Clark GT,Browne PA,Nakano M,Yang Q

更新日期：1993-11-01 00:00:00

abstract：:The etiology of dental caries reflects a complex interplay of biochemical, microbial, genetic, social and physical environmental, and health-influencing behavioral factors. This review updates the literature on the efficacy of behavioral approaches to caries prevention for children up to 18 y of age. Included were stu...

journal_title：Journal of dental research

authors： Albino J,Tiwari T

更新日期：2016-01-01 00:00:00

abstract：:Frequent consumption of cariogenic foods and bacterial infection are risk factors for early childhood caries (ECC). This study hypothesized that a short diet survey focused on frequency of foods, categorized by putative cariogenicity, would differentiate severe ECC (S-ECC) from caries-free children. Children's diets w...

journal_title：Journal of dental research

authors： Palmer CA,Kent R Jr,Loo CY,Hughes CV,Stutius E,Pradhan N,Dahlan M,Kanasi E,Arevalo Vasquez SS,Tanner AC

更新日期：2010-11-01 00:00:00

abstract：:The reaction of the microvasculature in the periodontal ligament to mechanical pressure is considered a very important phenomenon with respect to the biological background to orthodontic tooth movement. For clarification of the microvascular reaction to mechanical pressure, an experimental model that incorporated a ha...

journal_title：Journal of dental research

authors： Iida J,Inage S,Kurihara S,Miura F

更新日期：1992-06-01 00:00:00

abstract：:Samples of plaque and surface enamel were collected from 80 boys aged 14 years living in five communities in Ohio (USA). Mean (+/- SE) strontium concentrations in plaque were 1.43 +/- 0.18 micrograms/g (wet) and 12.34 +/- 1.63 micrograms/g (dry). For surface enamel, the mean concentration was 421 +/- 31 micrograms Sr/...

journal_title：Journal of dental research

authors： Curzon ME

更新日期：1985-12-01 00:00:00

abstract：:The aim of this study was to compare the effectiveness of dexamethasone administration following arthrocentesis of the temporomandibular joint (TMJ) with a placebo (saline). Twenty-eight participants with TMJ arthralgia were randomly assigned to two groups of a parallel double-blind RCT. In both groups, an arthrocente...

journal_title：Journal of dental research

authors： Huddleston Slater JJ,Vos LM,Stroy LP,Stegenga B

更新日期：2012-02-01 00:00:00

abstract：:The effect of different doses of polyadenylic and polyuridylic acids (poly A:U) was studied in control rats and in rats exposed to hypoxia. In the control rats, administration of different doses of poly A:U did not change the thickness of the epiphyseal plate or increase the incorporation of 3H-phenylalanine as judged...

journal_title：Journal of dental research

authors： Koo CS,Kim MK,Han SS

更新日期：1976-07-01 00:00:00

abstract：:Periodontitis is a complex, multifactorial chronic disease involving continuous interactions among bacteria, host immune/inflammatory responses, and modifying genetic and environmental factors. More than any other cytokine family, the interleukin (IL)-1 family includes key signaling molecules that trigger and perpetua...

journal_title：Journal of dental research

authors： Papathanasiou E,Conti P,Carinci F,Lauritano D,Theoharides TC

更新日期：2020-12-01 00:00:00

abstract：:Macrophage colony-stimulating factor (CSF-1) is a key regulatory cytokine for amelogenesis, and ameloblasts synthesize CSF-1. We hypothesized that PDGF stimulates DNA synthesis and regulates CSF-1 in these cells. We determined the effect of PDGF on CSF-1 expression using MEOE-3M ameloblasts as a model. By RT-PCR, MEOE...

journal_title：Journal of dental research

authors： Wittrant Y,Bhandari BS,Abboud H,Benson N,Woodruff K,MacDougall M,Abboud-Werner S

更新日期：2008-01-01 00:00:00

abstract：:Modulation of the phosphoinositide signal transduction pathway by arachidonic acid (AA) in collagenase-dispersed rat submandibular acinar cells was investigated. The muscarinic agonist, carbachol, stimulated PIP2 hydrolysis and the generation of IP3 to five-fold the control levels. This response was inhibited by 75% o...

journal_title：Journal of dental research

authors： Chung HC,Fleming N

更新日期：1992-08-01 00:00:00

abstract：:Molar teeth of four groups of Osborne-Mendel rats, kept on a cariogenic diet, were treated once per day for 48 days with either distilled water (solution C), a solution containing 0.05% chlorhexidine gluconate and 0.04% NaF, pH 5.8 (solution CXF), CXF plus 1000 ppm Sr (solution CXFS), or CXFS plus 1000 ppm Zn (solutio...

journal_title：Journal of dental research

authors： Luoma H,Seppä L,Koskinen M,Syrjänen S

更新日期：1984-10-01 00:00:00

abstract：:Teeth to be extracted for orthodontic reasons were filled in vivo with regular and fine-cut silver amalgams containing 1% and 5% SnF2. The teeth were extracted after 15 or 30 d, and the in vivo fluoride release and uptake by the dental tissues were studied using an electron microprobe analysis technique. The obtained ...

journal_title：Journal of dental research

authors： Souganidis DJ,Athanassouli TM,Papastathopoulos DS

更新日期：1981-02-01 00:00:00

abstract：:Previous studies suggest that salivary and pulp-derived host enzymes, matrix metalloproteinases (MMPs), may be involved in dentin caries pathogenesis. To study the inhibition of acid-activated human salivary MMPs by non-antimicrobial chemically modified tetracyclines (CMTs), we used a functional activity assay with 12...

journal_title：Journal of dental research

authors： Sulkala M,Wahlgren J,Larmas M,Sorsa T,Teronen O,Salo T,Tjäderhane L

更新日期：2001-06-01 00:00:00

abstract：:In this study, environmental stains were removed from maxillofacial elastomers by solvent extraction. Silastic 44210, an RTV silicone with proven color and physical property stability, was stained with lipstick, disclosing solution, and methylene blue. These stains were then removed by solvent extraction with each of ...

journal_title：Journal of dental research

authors： Yu R,Koran A,Raptis CN,Craig RG

更新日期：1981-10-01 00:00:00

abstract：:Selected anaerobic, capnophilic and facultative bacteria isolated from patients with various forms of periodontal health and disease were tested for their susceptibility to antibiotics and antimicrobial agents. Specific bactericidal and minimum inhibitory concentrations were compared to disc zone diameters, thereby ge...

journal_title：Journal of dental research

authors： Newman MG,Hulem C,Colgate J,Anselmo C

更新日期：1979-07-01 00:00:00

abstract：:A double-blind randomized clinical trial was performed in 6- to 7-yr-old schoolchildren to evaluate, in a 30-mo period, whether the caries increment on the distal surface of the second primary molars adjacent to permanent first molars sealed with fluoride release compounds would be lower with respect to those adjacent...

journal_title：Journal of dental research

authors： Cagetti MG,Carta G,Cocco F,Sale S,Congiu G,Mura A,Strohmenger L,Lingström P,Campus G,Italian Experimental Group on Oral Health.

更新日期：2014-07-01 00:00:00

abstract：:Pulpal blood flow was determined in 32 dogs ranging in age from 6 weeks to 18 months by the isotope fractionation method incorporating diffusible and nondiffusible tracers. Dogs were placed into selected age groups by the developmental status of the canine teeth. For the teeth sampled, the maxillary first, second, and...

journal_title：Journal of dental research

authors： Path MG,Meyer MW

更新日期：1977-10-01 00:00:00

abstract：:Experiments were performed to determine the role of the immune response in rat periodontal disease. Germ-free rats were fed defined antigen-free liquid diets or a diet containing ovalbumin(OVA) as a prototype antigen. The OVA-fed rats demonstrated increased gingival lymphocytes (mainly T at early times), OVA-sensitize...

journal_title：Journal of dental research

authors： Taubman MA,Yoshie H,Ebersole JL,Smith DJ,Olson CL

更新日期：1984-03-01 00:00:00

abstract：:The present study was conducted to investigate the role of proteolysis by matrix metalloproteinase 20 (MMP20) in regulating the initial formation of the enamel mineral structure during the secretory stage of amelogenesis, utilizing Mmp20-null mice that lack this essential protease. Ultrathin sagittal sections of maxil...

journal_title：Journal of dental research

authors： Yamazaki H,Tran B,Beniash E,Kwak SY,Margolis HC

更新日期：2019-04-01 00:00:00

abstract：:Apoptosis plays important roles in various stages of organogenesis. In this study, we hypothesized that apoptosis would play an important role in tooth morphogenesis. We examined the role of apoptosis in early tooth development by using a caspase inhibitor, z-VAD-fmk, concomitant with in vitro organ culture and tooth ...

journal_title：Journal of dental research

authors： Kim JY,Cha YG,Cho SW,Kim EJ,Lee MJ,Lee JM,Cai J,Ohshima H,Jung HS

更新日期：2006-06-01 00:00:00

abstract：:The major phosphoprotein in dentin is the aspartic acid and serine-rich protein called dentin phosphophoryn (DPP). DPP appears to be synthesized as a part of a larger compound protein, dentin sialophosphoprotein (DSPP). DSPP has never been isolated or detected in dentin extracts. It is now evident that DSPP is a chime...

journal_title：Journal of dental research

authors： Zhang Y,Song Y,Ravindran S,Gao Q,Huang CC,Ramachandran A,Kulkarni A,George A

更新日期：2014-02-01 00:00:00

abstract：:Despite recent advances revealing genetic factors influencing caries susceptibility, questions regarding the model of inheritance involved are yet to be addressed. We conducted a Complex Segregation Analysis on decayed teeth in a sample of homogenous, isolated families recruited from the Brazilian Amazon. A dominant, ...

journal_title：Journal of dental research

authors： Werneck RI,Lázaro FP,Cobat A,Grant AV,Xavier MB,Abel L,Alcaïs A,Trevilatto PC,Mira MT

更新日期：2011-06-01 00:00:00