The continuum of dental caries--evidence for a dynamic disease process.

abstract：:Cleidocranial dysplasia (CCD) is a skeletal dysplasia caused by heterozygous mutations of RUNX2, a gene that is essential for the mineralization of bone and tooth. We isolated primary dental pulp cells from a 10-y-old patient and tested their proliferative capacity, alkaline phosphatase activity, and ability to form m...

journal_title：Journal of dental research

authors： Yan WJ,Zhang CY,Yang X,Liu ZN,Wang XZ,Sun XY,Wang YX,Zheng SG

更新日期：2015-04-01 00:00:00

abstract：:The purpose of this investigation was to examine the inhibitory effects of aqueous extracts derived from the bark-containing sticks (Neem stick) of Azadirachta indica upon bacterial aggregation, growth, adhesion to hydroxyapatite, and production of insoluble glucan, which may affect in vitro plaque formation. Neem sti...

journal_title：Journal of dental research

authors： Wolinsky LE,Mania S,Nachnani S,Ling S

更新日期：1996-02-01 00:00:00

abstract：:Short-chain carboxylic acids (e.g., lactic acid, propionic acid, butyric acid) are metabolic by-products of bacterial metabolism which can accumulate in the gingival crevice. It is of no small consequence, therefore, that 1- to 5-mM concentrations of these acids exhibit significant biological activity, including the a...

journal_title：Journal of dental research

authors： Niederman R,Buyle-Bodin Y,Lu BY,Robinson P,Naleway C

更新日期：1997-01-01 00:00:00

abstract：:A double-blind randomized clinical trial was performed in 6- to 7-yr-old schoolchildren to evaluate, in a 30-mo period, whether the caries increment on the distal surface of the second primary molars adjacent to permanent first molars sealed with fluoride release compounds would be lower with respect to those adjacent...

journal_title：Journal of dental research

authors： Cagetti MG,Carta G,Cocco F,Sale S,Congiu G,Mura A,Strohmenger L,Lingström P,Campus G,Italian Experimental Group on Oral Health.

更新日期：2014-07-01 00:00:00

abstract：:Pieces of fresh rat incisor enamel were extracted with various buffer solutions and prepared for electron microscopy. I observed partial or complete removal of organic constituents, shrinkage of rods and interrods, separation of stippled material from the enamel, and partial decalcification. The results modify the con...

journal_title：Journal of dental research

authors： Kallenbach E

更新日期：1982-12-01 00:00:00

abstract：:Previous studies have indicated that tooth-bleaching agents contain potentially hazardous chemicals. The present study evaluates the acute toxicity of a commercially available tooth-bleaching agent and carbamide peroxide, which is the active bleaching ingredient. Rats were dosed by stomach gavage, i.e., via a stomach ...

journal_title：Journal of dental research

authors： Dahl JE,Becher R

更新日期：1995-02-01 00:00:00

abstract：:We analyzed the flow rate and composition of paraffin-stimulated whole saliva samples from 35 adult diabetic patients and their age- and sex-matched, non-diabetic, clinically healthy controls. All patients had insulin-dependent diabetes (IDDM) with a mean (+/- S.D.) duration of 14.0 +/- 9.1 years. The saliva analysis ...

journal_title：Journal of dental research

authors： Tenovuo J,Lehtonen OP,Viikari J,Larjava H,Vilja P,Tuohimaa P

更新日期：1986-01-01 00:00:00

abstract：:Phosphatases are involved in bone and tooth mineralization, but their mechanisms of action are not completely understood. Tissue-nonspecific alkaline phosphatase (TNAP, ALPL) regulates inhibitory extracellular pyrophosphate through its pyrophosphatase activity to control mineral propagation in the matrix; mice without...

journal_title：Journal of dental research

authors： McKee MD,Yadav MC,Foster BL,Somerman MJ,Farquharson C,Millán JL

更新日期：2013-08-01 00:00:00

abstract：:Streptococcus mutans strain JH1005 is a mutant that produces levels of bacteriocin activity three-fold-elevated than those produced by its parent, JH1001. A single infection regimen with JH1005 was found to result in persistent colonization of the teeth of all three adult subjects tested. This is a significant improve...

journal_title：Journal of dental research

authors： Hillman JD,Dzuback AL,Andrews SW

更新日期：1987-06-01 00:00:00

abstract：:Large mandibular defects are difficult to reconstruct with good functional and aesthetic outcomes because of the complex geometry of craniofacial bone. While the current gold standard is free tissue flap transfer, this treatment is limited in fidelity by the shape of the harvested tissue and can result in significant ...

journal_title：Journal of dental research

authors： Tatara AM,Wong ME,Mikos AG

更新日期：2014-12-01 00:00:00

abstract：:Mandibular prognathism is a common dentofacial phenotype with a substantial genetic component; however, few susceptibility loci have been mapped. Ethnicity is a risk factor for mandibular prognathism, and a relatively high prevalence is observed in Asian populations. The hypothesis of this study suggested that a speci...

journal_title：Journal of dental research

authors： Li Q,Li X,Zhang F,Chen F

更新日期：2011-01-01 00:00:00

abstract：:Growing interest in the treatment and prevention of Molar/Incisor Hypomineralization (MIH) warrants investigation into the protein composition of hypomineralized enamel. Hypothesizing abnormality akin to amelogenesis imperfecta, we profiled proteins in hypomineralized enamel from human permanent first molars using a b...

journal_title：Journal of dental research

authors： Mangum JE,Crombie FA,Kilpatrick N,Manton DJ,Hubbard MJ

更新日期：2010-10-01 00:00:00

abstract：:There is a large variability between and among individuals in the physiology of mastication, but it is not known whether this produces a similar variability in the particle sizes of food boluses at the end of the chewing process. Food boluses obtained just before swallowing were analyzed in ten subjects (aged 36.7 +/-...

journal_title：Journal of dental research

authors： Peyron MA,Mishellany A,Woda A

更新日期：2004-07-01 00:00:00

abstract：:The tissue-implant interfaces of functional and non-functional endosseous dental implants were compared histologically for up to one year post-operatively. Nonmineralized connective tissue zones (a "fibrous capsule") existed in all functional interfaces. Direct, or nearly direct, bone apposition to implants occurred i...

journal_title：Journal of dental research

authors： Brunski JB,Moccia AF Jr,Pollack SR,Korostoff E,Trachtenberg DI

更新日期：1979-10-01 00:00:00

abstract：:Bone marrow-derived mesenchymal stem/progenitor cells (BMSCs) are commonly used in regeneration therapy. The current primary source of BMSCs is the iliac crest; however, the procedure is associated with various burdens on the patient, including the risk of pain and infection. Hence, the possibility to collect BMSCs fr...

journal_title：Journal of dental research

authors： Nakajima R,Ono M,Hara ES,Oida Y,Shinkawa S,Pham HT,Akiyama K,Sonoyama W,Maekawa K,Kuboki T

更新日期：2014-11-01 00:00:00

abstract：:Nearly 100% of patients experience trauma to the trigeminal nerve during orthognathic surgery, impairing sensation and sensory function on the face. In a recent randomized clinical trial, people who performed sensory re-training exercises reported less difficulty related to residual numbness and decreased lip sensitiv...

journal_title：Journal of dental research

authors： Essick GK,Phillips C,Zuniga J

更新日期：2007-06-01 00:00:00

abstract：:Teeth to be extracted for orthodontic reasons were filled in vivo with regular and fine-cut silver amalgams containing 1% and 5% SnF2. The teeth were extracted after 15 or 30 d, and the in vivo fluoride release and uptake by the dental tissues were studied using an electron microprobe analysis technique. The obtained ...

journal_title：Journal of dental research

authors： Souganidis DJ,Athanassouli TM,Papastathopoulos DS

更新日期：1981-02-01 00:00:00

abstract：:The aim of this study was to determine whether the parotid gland, like other salivary glands, produces blood group antigens. A post-embedding immunogold staining (IGS) method for ABH antigens was applied to osmicated and nonosmicated, routinely prepared specimens of normal human parotid glands. A and B antigens were n...

journal_title：Journal of dental research

authors： Lantini MS,Cossu M

更新日期：1994-02-01 00:00:00

abstract：:Levels of mutans streptococci in plaque samples from margins of Class II amalgam (Dispersalloy), composite (P-10), and glass-ionomer (Ketac Silver) restorations were compared. Fifty-one children, each having one of the restorations in a permanent first molar, were part of an inter-individual comparison, giving 17 rest...

journal_title：Journal of dental research

authors： Svanberg M,Mjör IA,Orstavik D

更新日期：1990-03-01 00:00:00

abstract：:Adenosine has various biological effects on human gingival fibroblasts (HGF) and epithelial cells closely associated with inflammation, such as cytokine production and cell adhesion. However, the mechanism of adenosine formation in periodontal tissues is not yet defined. In this study, we examined the involvement of C...

journal_title：Journal of dental research

authors： Hashikawa T,Takedachi M,Terakura M,Saho T,Yamada S,Thompson LF,Shimabukuro Y,Murakami S

更新日期：2003-11-01 00:00:00

abstract：:It was recently reported that human periapical cysts (hPCys), a commonly occurring odontogenic cystic lesion of inflammatory origin, contain mesenchymal stem cells (MSCs) with the capacity for self-renewal and multilineage differentiation. In this study, periapical inflammatory cysts were compared with dental pulp to ...

journal_title：Journal of dental research

authors： Marrelli M,Paduano F,Tatullo M

更新日期：2015-06-01 00:00:00

abstract：:Previous studies of tooth size in twins and their families have suggested a high degree of genetic control, although there have been difficulties separating the various genetic and environmental effects. A genetic analysis of variation in crown size of the permanent incisors of South Australian twins was carried out, ...

journal_title：Journal of dental research

authors： Dempsey PJ,Townsend GC,Martin NG,Neale MC

更新日期：1995-07-01 00:00:00

abstract：:Although it is known that diabetes impairs oral wound healing, relatively little is known about the cellular parameters affected, particularly in connective tissue. This study investigated the hypothesis that diabetes impairs connective tissue formation in healing gingiva, and that impaired healing is associated with ...

journal_title：Journal of dental research

authors： Desta T,Li J,Chino T,Graves DT

更新日期：2010-06-01 00:00:00

abstract：:Mutations and common polymorphisms in interferon regulatory factor 6 ( IRF6) are associated with both syndromic and nonsyndromic forms of cleft lip/palate (CLP). To date, much of the focus on this transcription factor has been on identifying its direct targets and the gene regulatory network in which it operates. Nota...

journal_title：Journal of dental research

authors： Parada-Sanchez MT,Chu EY,Cox LL,Undurty SS,Standley JM,Murray JC,Cox TC

更新日期：2017-10-01 00:00:00

abstract：:The goal of nonrestorative or non- and microinvasive caries treatment (fluoride- and nonfluoride-based interventions) is to manage the caries disease process at a lesion level and minimize the loss of sound tooth structure. The purpose of this systematic review and network meta-analysis was to summarize the available ...

journal_title：Journal of dental research

authors： Urquhart O,Tampi MP,Pilcher L,Slayton RL,Araujo MWB,Fontana M,Guzmán-Armstrong S,Nascimento MM,Nový BB,Tinanoff N,Weyant RJ,Wolff MS,Young DA,Zero DT,Brignardello-Petersen R,Banfield L,Parikh A,Joshi G,Carrasco-Labra

更新日期：2019-01-01 00:00:00

abstract：:Joining a brittle veneer to a strong ceramic core with an adhesive offers potential benefits over current fabrication methods for all-ceramic crowns. We tested the hypothesis that such joining can withstand subsurface radial cracking in the veneer, from enhanced flexure in occlusal loading, as well as in the core. Cri...

journal_title：Journal of dental research

authors： Lee JJ,Kwon JY,Bhowmick S,Lloyd IK,Rekow ED,Lawn BR

更新日期：2008-04-01 00:00:00

abstract：:Experimental marginal leakage of high- and low-Cu amalgam restorations placed in acrylic teeth, where the cavities were untreated or painted with denatured collagen and/or a CaP slurry, was assessed after specimens were stored in a 1% NaCl solution for ten days and for one yr. All specimens stored for ten days showed ...

journal_title：Journal of dental research

authors： Jodaikin A,Grossman ES

更新日期：1984-08-01 00:00:00

abstract：:A frameshift mutation recently identified within the paired domain of the transcription factor, PAX9, has been linked to a unique form of oligodontia in a single, multigenerational family (Stockton et al., 2000). We now describe the phenotypic and segregation analyses of this remarkable kindred, the initial approach t...

journal_title：Journal of dental research

authors： Goldenberg M,Das P,Messersmith M,Stockton DW,Patel PI,D'Souza RN

更新日期：2000-07-01 00:00:00

abstract：:Our observations confirm the previously reported observation that multinucleated cells develop within a two-week period in cat bone-marrow cultures. Calcitonin induces cytoplasmic contraction in these multinucleated cells, which indicates that they resemble osteoclasts. After seven days of culture, cat bone-marrow cul...

journal_title：Journal of dental research

authors： Pharoah MJ,Heersche JN

更新日期：1986-07-01 00:00:00

abstract：:Previous studies have demonstrated that antibodies against cholinoreceptors of exocrine glands correlate with dry mouth in persons with primary Sjögren syndrome (pSS). The aim of the present investigation was to establish if serum IgG antibodies (pSS IgG) were able to interact with cholinoreceptors in rat submandibula...

journal_title：Journal of dental research

authors： Reina S,Orman B,Anaya JM,Sterin-Borda L,Borda E

更新日期：2007-09-01 00:00:00