The identification of a novel locus for mandibular prognathism in the Han Chinese population.

abstract：:We tested whether orthodontic tooth movement (OTM) could be blocked by local administration of echistatin or an arginine-glycine-aspartic acid (RGD) peptide, agents known to perturb bone remodeling, adjacent to maxillary molars in rats. These molecules were incorporated into ethylene-vinyl acetate (ELVAX), a non-biode...

journal_title：Journal of dental research

authors： Dolce C,Vakani A,Archer L,Morris-Wiman JA,Holliday LS

更新日期：2003-09-01 00:00:00

abstract：:Streptococcus mutans produces 3 types of glucosyltransferase (GTF), whose cooperative action is considered to be essential for its cellular adherence to the tooth surface. However, the precise mechanisms for synthesizing adhesive glucans and the specific roles of each GTF in cellular adherence to smooth surfaces have ...

journal_title：Journal of dental research

authors： Ooshima T,Matsumura M,Hoshino T,Kawabata S,Sobue S,Fujiwara T

更新日期：2001-07-01 00:00:00

abstract：:Cellular hypoxia may be a useful indication of tissue distress in the dental pulp that could be used to investigate the early stages of pulpal responses. Tritiated misonidazole (3H-MISO) is a marker which preferentially labels cells with decreased oxygen tension (hypoxia). The experiments reported here were carried ou...

journal_title：Journal of dental research

authors： Baumgardner KR,Walton RE,Osborne JW,Born JL

更新日期：1996-10-01 00:00:00

abstract：:It is claimed that dental fluorosis in both deciduous and permanent teeth is increasing in fluoridated and non-fluoridated communities. What is unclear is whether fluoride-induced enamel opacities in the deciduous dentition are associated with the subsequent appearance of enamel defects in the permanent dentition. The...

journal_title：Journal of dental research

authors： Milsom KM,Woodward M,Haran D,Lennon MA

更新日期：1996-04-01 00:00:00

abstract：:Sintered samples of modifying porcelains of various colors and manufacturers were analyzed using reflectance spectrophotometry. Color designations are reported according to practices of the Commission Internationale de l'Eclairage (International Commission for Illumination), and color names were assigned based on a me...

journal_title：Journal of dental research

authors： Johnston WM,O'Brien WJ

更新日期：1982-03-01 00:00:00

abstract：:Proteolytic hydrolysis of casein and porcine or bovine glycoproteins by S mutans was demonstrated in the present study. Caseinolytic activity was found in both the soluble contents of the cells and the cellular debris after rupture of the cells. However, caseinolytic activity could not be demonstrated after growth in ...

journal_title：Journal of dental research

authors： Cowman RA,Perrella MM,Fitzgerald RJ

更新日期：1976-05-01 00:00:00

abstract：:This study was conducted to test the hypothesis that physiological changes which occur during aging increase the biological impact of fluoride and reduce the threshold of safe fluoride exposure. Four groups of rats were fed a low-fluoride diet (< 1.2 ppm) ad libitum and received 0, 5, 15, or 50 ppm fluoride in their d...

journal_title：Journal of dental research

authors： Dunipace AJ,Brizendine EJ,Zhang W,Wilson ME,Miller LL,Katz BP,Warrick JM,Stookey GK

更新日期：1995-01-01 00:00:00

abstract：:The objectives of this study were 1) to provide an estimate of the value of the intraclass correlation coefficient (ICC) for dental caries data at tooth and surface level, 2) to provide an estimate of the design effect (DE) to be used in the determination of sample size estimates for future dental surveys, and 3) to e...

journal_title：Journal of dental research

authors： Masood M,Masood Y,Newton JT

更新日期：2015-02-01 00:00:00

abstract：:Enamel crystals in the demineralized zones in early caries lesions of human teeth were observed by high-resolution electron microscopy. The enamel crystals frequently exhibited perforations in their centers and defects of various sizes on their lateral surfaces. There were a number of small electron-lucent spots, sugg...

journal_title：Journal of dental research

authors： Tohda H,Takuma S,Tanaka N

更新日期：1987-11-01 00:00:00

abstract：:Lipopolysaccharide (LPS) from the Gram-negative pathogen Porphyromonas gingivalis (Pg) stimulates cytokine secretion in immune cells, and thereby initiates the inflammation associated with periodontitis. Modulation of pro-inflammatory cytokine activity is a plausible therapeutic target in periodontal disease. Vasoacti...

journal_title：Journal of dental research

authors： Foster N,Cheetham J,Taylor JJ,Preshaw PM

更新日期：2005-11-01 00:00:00

abstract：:Previous studies have indicated that tooth-bleaching agents contain potentially hazardous chemicals. The present study evaluates the acute toxicity of a commercially available tooth-bleaching agent and carbamide peroxide, which is the active bleaching ingredient. Rats were dosed by stomach gavage, i.e., via a stomach ...

journal_title：Journal of dental research

authors： Dahl JE,Becher R

更新日期：1995-02-01 00:00:00

abstract：:Nitric oxide (.NO) modulates the activity of the endocrine system in the behavioral response to stress. The purpose of this study was to investigate the effect of restraining the body of an animal on expression of neuronal nitric oxide synthase (nNOS) in the paraventricular nucleus (PVN) of the hypothalamus, and the i...

journal_title：Journal of dental research

authors： Hori N,Lee MC,Sasaguri K,Ishii H,Kamei M,Kimoto K,Toyoda M,Sato S

更新日期：2005-07-01 00:00:00

abstract：:Enamel fluorosis can occur following either an acute or chronic exposure to fluoride during tooth formation. Fluorosed enamel is characterized by a retention of amelogenins in the early-maturation stage, and by the formation of a more porous enamel with a subsurface hypomineralization. The mechanisms by which fluoride...

journal_title：Journal of dental research

authors： DenBesten PK,Thariani H

更新日期：1992-05-01 00:00:00

abstract：:The goal of nonrestorative or non- and microinvasive caries treatment (fluoride- and nonfluoride-based interventions) is to manage the caries disease process at a lesion level and minimize the loss of sound tooth structure. The purpose of this systematic review and network meta-analysis was to summarize the available ...

journal_title：Journal of dental research

authors： Urquhart O,Tampi MP,Pilcher L,Slayton RL,Araujo MWB,Fontana M,Guzmán-Armstrong S,Nascimento MM,Nový BB,Tinanoff N,Weyant RJ,Wolff MS,Young DA,Zero DT,Brignardello-Petersen R,Banfield L,Parikh A,Joshi G,Carrasco-Labra

更新日期：2019-01-01 00:00:00

abstract：:Dental amalgam restorations are a significant source of mercury exposure in the human population, but their potential to cause systemic health effects is highly disputed. We examined effects on the immune system by giving genetically mercury-susceptible Brown Norway (BN) rats and mercury-resistant Lewis (LE) rats silv...

journal_title：Journal of dental research

authors： Hultman P,Lindh U,Hörsted-Bindslev P

更新日期：1998-06-01 00:00:00

abstract：:Studies on mechanisms underlying the differentiation of dental pulp stem cells are critical for the understanding of the biology of odontogenesis and for dental tissue engineering. Here, we tested the hypothesis that stem cells from exfoliated deciduous teeth (SHED) differentiate into functional odontoblasts and endot...

journal_title：Journal of dental research

authors： Sakai VT,Zhang Z,Dong Z,Neiva KG,Machado MA,Shi S,Santos CF,Nör JE

更新日期：2010-08-01 00:00:00

abstract：:The aim of this study was to examine the association between the bone mass (bone mineral content [BMC]) and hypomineralized second primary molars (HSPMs)/molar incisor hypomineralization (MIH) in 6-y-old children. This cross-sectional study was embedded in the Generation R Study, a population-based prospective cohort ...

journal_title：Journal of dental research

authors： van der Tas JT,Elfrink ME,Vucic S,Heppe DH,Veerkamp JS,Jaddoe VW,Rivadeneira F,Hofman A,Moll HA,Wolvius EB

更新日期：2016-04-01 00:00:00

abstract：:We have investigated the role of the activation of nuclear poly(ADP-ribose) polymerase (PARP) enzyme, a mediator of downstream nitric oxide toxicity, using a combined approach of pharmacological inhibition and genetic disruption in a ligature-induced-periodontitis model in rats and mice. Immunohistochemical analysis r...

journal_title：Journal of dental research

authors： Lohinai Z,Mabley JG,Fehér E,Marton A,Komjáti K,Szabó C

更新日期：2003-12-01 00:00:00

abstract：:Teeth to be extracted for orthodontic reasons were filled in vivo with regular and fine-cut silver amalgams containing 1% and 5% SnF2. The teeth were extracted after 15 or 30 d, and the in vivo fluoride release and uptake by the dental tissues were studied using an electron microprobe analysis technique. The obtained ...

journal_title：Journal of dental research

authors： Souganidis DJ,Athanassouli TM,Papastathopoulos DS

更新日期：1981-02-01 00:00:00

abstract：:It is generally accepted that glass ionomers inhibit secondary caries in vivo, and data from in vitro studies support this effect. The aim of this review was a systematic assessment, from the literature, of clinical evidence for the ability of glass-ionomer restoratives to inhibit secondary caries at the restoration m...

journal_title：Journal of dental research

authors： Randall RC,Wilson NH

更新日期：1999-02-01 00:00:00

abstract：:We examined 102 children born and reared in an area of rural Kenya with 2 ppm fluoride in the drinking water for dental fluorosis, using the index developed by Thylstrup and Fejerskov (1978). The prevalence of dental fluorosis was 100%, 92% of all teeth exhibited a TFI score of 4 or higher, and 50% of the children had...

journal_title：Journal of dental research

authors： Manji F,Baelum V,Fejerskov O

更新日期：1986-05-01 00:00:00

abstract：:Mechanosensitive osteocytes are essential for bone remodeling. Nitric oxide, an important regulator of bone remodeling, is produced by osteocytes through the activity of constitutive endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). We hypothesized that these enzymes regulate the tiss...

journal_title：Journal of dental research

authors： Tan SD,Xie R,Klein-Nulend J,van Rheden RE,Bronckers AL,Kuijpers-Jagtman AM,Von den Hoff JW,Maltha JC

更新日期：2009-03-01 00:00:00

abstract：:A multiple logistic regression analysis was used to compute the odds ratios for 11 common occlusal features for asymptomatic controls (n = 147) vs. five temporomandibular disorder groups: Disc Displacement with Reduction (n = 81), Disc Displacement without Reduction (n = 48), Osteoarthrosis with Disc Displacement Hist...

journal_title：Journal of dental research

authors： Pullinger AG,Seligman DA,Gornbein JA

更新日期：1993-06-01 00:00:00

abstract：:Chronic periodontitis is a multi-factorial disease involving anaerobic bacteria and the generation of an inflammatory response, including the production of metalloproteinases, pro-inflammatory cytokines, and eicosanoids. Hypochlorous acid (HOCl) and taurine-N-monochloramine (TauCl) are the end-products of the neutroph...

journal_title：Journal of dental research

authors： Mainnemare A,Mégarbane B,Soueidan A,Daniel A,Chapple IL

更新日期：2004-11-01 00:00:00

abstract：:Fluid transudation through simplified dentin adhesives can occur in bonded vital crown dentin, since these adhesives behave as permeable membranes after polymerization. The effect of adhesive permeability in endodontically treated teeth is unknown. This study examined the hypothesis that in vivo fluid movement through...

journal_title：Journal of dental research

authors： Chersoni S,Acquaviva GL,Prati C,Ferrari M,Grandini S,Pashley DH,Tay FR

更新日期：2005-03-01 00:00:00

abstract：:In the current theme of dental pulp regeneration, biological and synthetic scaffolds are becoming a potential therapy for pulp revitalization. The goal is to provide a suitable environment for cellular infiltration, proliferation, and differentiation. The extracellular matrix (ECM) represents a natural scaffold materi...

journal_title：Journal of dental research

authors： Alqahtani Q,Zaky SH,Patil A,Beniash E,Ray H,Sfeir C

更新日期：2018-12-01 00:00:00

abstract：:It was the aim of this 24-mo randomized controlled clinical trial to investigate whether the survival of a single median implant placed in the edentulous mandible to retain a complete denture is not compromised by immediate loading. Secondary outcomes were differences in prosthetic complications between the loading pr...

journal_title：Journal of dental research

authors： Kern M,Att W,Fritzer E,Kappel S,Luthardt RG,Mundt T,Reissmann DR,Rädel M,Stiesch M,Wolfart S,Passia N

更新日期：2018-02-01 00:00:00

abstract：:Three single-composition, high-copper amalgams were analyzed for the composition of their before- and after-reaction phases. The method used was electron probe microanalysis. The results may be summarized as follows: All alloys consist essentially of Ag3Sn (gamma), Cu3Sn (epsilon), and, in some cases, Ag4Sn (beta). Wh...

journal_title：Journal of dental research

authors： Mahler DB,Adey JD

更新日期：1984-06-01 00:00:00

abstract：:The flexure moduli of elasticity of solid and multi-stranded orthodontic wires were determined. Results for the solid wires approximated their tensile values, but the differences were statistically significant for the stainless steel, chromium-cobalt-nickel, and nickel-titanium alloys. The flexure moduli of the multi-...

journal_title：Journal of dental research

authors： Goldberg AJ,Morton J,Burstone CJ

更新日期：1983-07-01 00:00:00

abstract：:The biocompatibility of two implant materials, vitallium and poly-methyl methacrylate (PMMA), was evaluated in an animal model in which bone formation and resorption are independent of each other. Neither material accelerated resorption, but formation was inhibited 12% by vitallium and 38% by PMMA. When three PMMA pre...

journal_title：Journal of dental research

authors： Garcia DA,Sullivan TM,O'Neill DM

更新日期：1981-01-01 00:00:00