Biological mechanisms of fluorosis and level and timing of systemic exposure to fluoride with respect to fluorosis.

abstract：:The oral microbiome consists of a planktonic microbiome residing in saliva and an adhering microbiome (the biofilm adhering to oral hard and soft tissues). Here we hypothesized that possible differences in microbial composition of the planktonic and adhering oral microbiome on teeth can be related to the forces by whi...

journal_title：Journal of dental research

authors： Wessel SW,Chen Y,Maitra A,van den Heuvel ER,Slomp AM,Busscher HJ,van der Mei HC

更新日期：2014-01-01 00:00:00

abstract：:Bone resorption beneath a maxillary complete denture was simulated by the finite element method, assuming that a threshold of compressive strain exists in the alveolar bone above which the resorption occurred. The pattern of predicted resorption was observed when 100 N of force was applied to three positions occlusall...

journal_title：Journal of dental research

authors： Maeda Y,Wood WW

更新日期：1989-09-01 00:00:00

abstract：:Current knowledge regarding the sensitivity of the teeth to forces is based on psychophysical experiments that measured touch detection thresholds under static jaw conditions. It is not known whether jaw movements alter the perception of forces applied to the teeth, but, based on limb movement studies, it is hypothesi...

journal_title：Journal of dental research

authors： Sowman PF,Brinkworth RS,Türker KS

更新日期：2010-04-01 00:00:00

abstract：:There is a large variability between and among individuals in the physiology of mastication, but it is not known whether this produces a similar variability in the particle sizes of food boluses at the end of the chewing process. Food boluses obtained just before swallowing were analyzed in ten subjects (aged 36.7 +/-...

journal_title：Journal of dental research

authors： Peyron MA,Mishellany A,Woda A

更新日期：2004-07-01 00:00:00

abstract：:The extent of dental tissue destruction during the treatment of white spot lesions (WSLs) increases with the severity of the lesion. If the depth and shape of WSLs can be predicted with a noninvasive diagnostic method before dental caries treatment, more conservative interventions can be planned. Given the superiority...

journal_title：Journal of dental research

authors： Kim J,Shin TJ,Kong HJ,Hwang JY,Hyun HK

更新日期：2019-03-01 00:00:00

abstract：:Cleidocranial dysplasia (CCD) is a skeletal dysplasia caused by heterozygous mutations of RUNX2, a gene that is essential for the mineralization of bone and tooth. We isolated primary dental pulp cells from a 10-y-old patient and tested their proliferative capacity, alkaline phosphatase activity, and ability to form m...

journal_title：Journal of dental research

authors： Yan WJ,Zhang CY,Yang X,Liu ZN,Wang XZ,Sun XY,Wang YX,Zheng SG

更新日期：2015-04-01 00:00:00

abstract：:The limited durability of resin-dentin bonds severely compromises the lifetime of tooth-colored restorations. Bond degradation occurs via hydrolysis of suboptimally polymerized hydrophilic resin components and degradation of water-rich, resin-sparse collagen matrices by matrix metalloproteinases (MMPs) and cysteine ca...

journal_title：Journal of dental research

authors： Liu Y,Tjäderhane L,Breschi L,Mazzoni A,Li N,Mao J,Pashley DH,Tay FR

更新日期：2011-08-01 00:00:00

abstract：:The mechanism of formation of nodular material on the surface of a Pd-Ag-based alloy for porcelain during pre-porcelainization heat treatment was investigated using scanning electron microscopy, x-ray diffraction, quantitative metallography, and Auger electron spectroscopy. The nodules were found to form by a Nabarro-...

journal_title：Journal of dental research

authors： Mackert JR Jr,Ringle RD,Fairhurst CW

更新日期：1983-12-01 00:00:00

abstract：:The lack of a reliable bond test has hindered the elucidation of the mechanism for porcelain-metal bonding in dental systems, because a test capable of detecting differences among porcelain-metal bonds of various qualities is required before the reasons for these differences may be ascertained. A method was developed ...

journal_title：Journal of dental research

authors： Mackert JR Jr,Ringle RD,Parry EE,Evans AL,Fairhurst CW

更新日期：1988-02-01 00:00:00

abstract：:The human mandibular condyle has a parasagittal plate-like trabecular structure. We tested the hypothesis that this structure reflects the mechanical loading of the condyle. We developed a finite element model of the condyle to analyze the strains occurring during static compressive loading. The principal strains in t...

journal_title：Journal of dental research

authors： van Ruijven LJ,Giesen EB,van Eijden TM

更新日期：2002-10-01 00:00:00

abstract：:The ability of human oral bacteria to inhibit Streptococcus mutans was studied under a variety of in vitro conditions using an agar overlay assay. Extensive inherent variability in microbial antagonism by certain organisms was demonstrated. Antagonistic activity was also significantly influenced by changes in the assa...

journal_title：Journal of dental research

authors： Deyloff JL,Sanders CC

更新日期：1980-11-01 00:00:00

abstract：:Periodontal ligament (PDL) cells play an important role in maintaining the homeostasis of periodontal tissues. However, it is not known how PDL cells contribute to osteoclastogenesis. In this study, we examined the consequences of cell-to-cell interactions between peripheral blood mononuclear cells (PBMCs) and PDL cel...

journal_title：Journal of dental research

authors： Kanzaki H,Chiba M,Shimizu Y,Mitani H

更新日期：2001-03-01 00:00:00

abstract：:Previous studies have demonstrated that antibodies against cholinoreceptors of exocrine glands correlate with dry mouth in persons with primary Sjögren syndrome (pSS). The aim of the present investigation was to establish if serum IgG antibodies (pSS IgG) were able to interact with cholinoreceptors in rat submandibula...

journal_title：Journal of dental research

authors： Reina S,Orman B,Anaya JM,Sterin-Borda L,Borda E

更新日期：2007-09-01 00:00:00

abstract：:Damage to the dentin matrix investigates the proliferation and mobilization of dental progenitor cells to the injury site, the mechanisms of which are not defined. EphB receptors and ephrin-B ligands expressed within the perivascular niche of dental pulp have been implicated following tooth injury. We propose that ele...

journal_title：Journal of dental research

authors： Arthur A,Koblar S,Shi S,Gronthos S

更新日期：2009-09-01 00:00:00

abstract：:After cheek pouch carcinomas were induced in hamsters by the application of dimethylbenzanthracene (DMBA) to the right pouch for 13 weeks, the animals were divided into four groups and observed for seven more weeks. The control group received no further treatment, two experimental groups had incisional biopsies perfor...

journal_title：Journal of dental research

authors： Tsiklakis K,Wood NK,Toto PD,Doemling DB

更新日期：1986-06-01 00:00:00

abstract：:Submandibular glands from young adult and aged male and female rats have been examined and various descriptive parameters obtained. Several sex differences were observed with tissue from young and old animals. Sex differences were found in the gland contents of DNA, protein, and sialic acid and in some protein compone...

journal_title：Journal of dental research

authors： Kuyatt BL,Baum BJ

更新日期：1981-05-01 00:00:00

abstract：:The purpose of the study was to determine the exposure times needed to harden a light-activated composite cement through various thicknesses of porcelain. A negative exponential model was developed with which the relative hardness of a composite could be predicted from the product of the exposure time and the square r...

journal_title：Journal of dental research

authors： Chan KC,Boyer DB

更新日期：1989-03-01 00:00:00

abstract：:Several studies have shown that surgical detachment of marginal gingiva close to the cervical cementum of molar teeth in a rat mandible is a distinct stimulus for alveolar bone resorption. Recently, we found that P2X4, an ATP-receptor, is significantly up-regulated in marginal gingival cells soon after surgery. We hyp...

journal_title：Journal of dental research

authors： Binderman I,Bahar H,Jacob-Hirsch J,Zeligson S,Amariglio N,Rechavi G,Shoham S,Yaffe A

更新日期：2007-02-01 00:00:00

abstract：:Dental composites develop residual stresses during polymerization due to shrinkage. These stresses may change with time because of relaxation and water sorption in the oral environment. This phenomenon is likely dependent on the composition of the materials, specifically their hydrophilic characteristics, and could re...

journal_title：Journal of dental research

authors： Park JW,Ferracane JL

更新日期：2014-02-01 00:00:00

abstract：:microRNAs could be mechanosensitive and emerge as critical posttranscriptional regulators in the bone-remodeling process. During orthodontic tooth movement (OTM), the application of mechanical force induces alveolar bone remodeling, but whether microRNAs respond to orthodontic force and contribute to OTM is unknown. m...

journal_title：Journal of dental research

authors： Chen N,Sui BD,Hu CH,Cao J,Zheng CX,Hou R,Yang ZK,Zhao P,Chen Q,Yang QJ,Jin Y,Jin F

更新日期：2016-11-01 00:00:00

abstract：:Inferior alveolar nerve (IAN) injury induces persistent ectopic pain which spreads to a wide area in the orofacial region. Its exact mechanism remains unclear. We investigated the involvement of nitric oxide (NO) in relation to ectopic orofacial pain caused by IAN transection (IANX). We assessed the changes in mechani...

journal_title：Journal of dental research

authors： Sugiyama T,Shinoda M,Watase T,Honda K,Ito R,Kaji K,Urata K,Lee J,Ohara K,Takahashi O,Echizenya S,Iwata K

更新日期：2013-12-01 00:00:00

abstract：:Bone remodeling is a complex process regulated by several mediators. Recent work has revealed that cytokines and growth factors have significant effects on bone cell metabolism. However, little information is available concerning the production of cytokines during orthodontic tooth movement in human subjects, and ther...

journal_title：Journal of dental research

authors： Uematsu S,Mogi M,Deguchi T

更新日期：1996-01-01 00:00:00

abstract：:The effects of different doses of p-tyramine injected i.v. and i.p. on salivary flow rates and proteins secreted by the submandibular glands of rats were studied with and without various types of autonomic blockers and two enzyme inhibitors. The salivary flow rates and the amounts of protein secreted progressively inc...

journal_title：Journal of dental research

authors： Okina A,Hidaka S,Tashiro M,Abe K

更新日期：1993-05-01 00:00:00

abstract：:The effects of substituting gluconate for extracellular Cl, and of treatment with various ion transport blockers, on cytosol pH (pHi) and secretion by the acetylcholine stimulated rat mandibular gland were studied in vitro. Gluconate replacement increased pHi from 7.12 +/- 0.02 to 7.27 +/- 0.04, caused secretory rate ...

journal_title：Journal of dental research

authors： Young JA,Cook DI,Evans LA,Pirani D

更新日期：1987-02-01 00:00:00

abstract：:When one uses composite resins, the curing contraction, the stiffness of the material, and the strength of the vulnerable dentinal bond are important factors in determining the marginal adaptation of the restoration. Calculations based on these intrinsic material properties have indicated that both bulk placement and ...

journal_title：Journal of dental research

authors： Kemp-Scholte CM,Davidson CL

更新日期：1988-05-01 00:00:00

abstract：:Recent functional animal studies have reported that the motor control of masticatory muscle function is bilaterally guided by both hemispheres, which may fundamentally differ from the cortical control of limb muscle function. In this study, we investigated whether unilateral cortical brain infarction induces different...

journal_title：Journal of dental research

authors： Kemppainen P,Waltimo A,Palomäki H,Salonen O,Könönen M,Kaste M

更新日期：1999-12-01 00:00:00

abstract：:While dental pulp appears to be able to form mineralized matrices that do not always resemble dentin, the precise characteristics of the hard tissue and the mechanism of its induction remain unknown. Therefore, we evaluated hard tissue induced by transplantation of pulp into subcutaneous tissue. Seven days after trans...

journal_title：Journal of dental research

authors： Hosoya A,Nakamura H,Ninomiya T,Hoshi K,Yoshiba K,Yoshiba N,Takahashi M,Okabe T,Sahara N,Yamada H,Kasahara E,Ozawa H

更新日期：2007-05-01 00:00:00

abstract：:An intra-oral model system has been developed which uses a single-section technique for before-and-after measurements on the same tissue. This model allows for placement of sections of enamel at both buccal and approximal sites. These sections may be sound or possess white-spot lesions. This allows for the evaluation ...

journal_title：Journal of dental research

authors： Wefel JS,Maharry GJ,Jensen ME,Harless JD

更新日期：1987-09-01 00:00:00

abstract：:Recent evidence implicates endothelin in nociception, but it is unclear how endothelin activates trigeminal ganglion (TRG) neurons. In the present study, we investigated the expression of the endothelin receptors ETA and ETB and endothelin-induced responses in rat TRG neurons. Double-immunofluorescence studies demonst...

journal_title：Journal of dental research

authors： Yamamoto T,Ono K,Hitomi S,Harano N,Sago T,Yoshida M,Nunomaki M,Shiiba S,Watanabe S,Nakanishi O,Inenaga K

更新日期：2013-04-01 00:00:00

abstract：:The Kubelka-Munk (K-M) theory provides a reflectance model for translucent materials placed on backings of different colors. We hypothesize that Kubelka-Munk (K-M) theoretical diffuse reflectance spectra of dentin and enamel are in good agreement with observed diffuse reflectance. The aim of this study was to measure ...

journal_title：Journal of dental research

authors： Ragain JC Jr,Johnston WM

更新日期：2001-02-01 00:00:00