Abstract:
:It is claimed that dental fluorosis in both deciduous and permanent teeth is increasing in fluoridated and non-fluoridated communities. What is unclear is whether fluoride-induced enamel opacities in the deciduous dentition are associated with the subsequent appearance of enamel defects in the permanent dentition. The aim of this study was to establish whether a relationship existed between the presence of diffuse enamel defects on the deciduous molars and permanent incisors of schoolchildren who were lifetime residents in an optimally fluoridated community in Cheshire, England. The dentitions of eight-and nine-year-old children were examined by two examiners, each unaware of the findings of the other. There was a significant increased risk of diffuse enamel defects in the permanent incisors for those children who presented with diffuse defects on their first deciduous molars (Relative Risk, 1.45; 95% confidence interval, 1.05 to 2.0) or second deciduous molars (Relative Risk, 1.86; 95% confidence interval, 1.36 to 2.54). In light of these findings, it is worth considering the potential of the presence of enamel defects in deciduous molars in children aged 1 to 3 years as a predictor of the future appearance of similar lesions in their permanent incisors.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Milsom KM,Woodward M,Haran D,Lennon MAdoi
10.1177/00220345960750040301subject
Has Abstractpub_date
1996-04-01 00:00:00pages
1015-8issue
4eissn
0022-0345issn
1544-0591journal_volume
75pub_type
杂志文章abstract::This paper discusses loosely bound fluoride and its role in dental caries and prevention. Loosely bound fluoride (abbr. by Fa) is fluoride adsorbed onto enamel mineral crystallites. Several recent studies indicate that a high total level of fluoride in enamel does not guarantee protection against caries. This leads to...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345900690S118
更新日期:1990-02-01 00:00:00
abstract::A major extracellular protein of cultured adult human gingival fibroblasts was shown to be fibronectin by indirect immunofluorescence, lactoperoxidase catalyzed iodination and metabolic radiolabeling. Fibronectin preparations from these cells possessed the biological properties of agglutination of sheep red blood cell...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590031301
更新日期:1980-03-01 00:00:00
abstract::In order for the role of parotid amylase in starch digestion in the gastro-intestinal tracts of diabetic rats to be clarified, this study investigated the effect of parotid-duct ligation on both amylase secretion from the parotid glands and pancreas into the gastro-intestinal tract and on starch digestion in the gastr...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345890680091501
更新日期:1989-09-01 00:00:00
abstract::Previous studies of tooth size in twins and their families have suggested a high degree of genetic control, although there have been difficulties separating the various genetic and environmental effects. A genetic analysis of variation in crown size of the permanent incisors of South Australian twins was carried out, ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345950740071101
更新日期:1995-07-01 00:00:00
abstract::Amelogenin and ameloblastin, the major enamel matrix proteins, are important for enamel mineralization. To identify their synergistic roles in enamel development, we generated Amel X(-/-)/Ambn(-/-) mice. These mice showed additional enamel defects in comparison with Amel X(-/-) or Ambn(-/-) mice. In 7-day-old Amel X(-...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509334749
更新日期:2009-04-01 00:00:00
abstract::Zirconia-based restorations often fracture from chipping and/or delamination of the porcelain veneers. We hypothesized that veneer chipping/delamination is a result of the propagation of near-contact-induced partial cone cracks on the occlusal surface under mastication. Masticatory loading involves the opposing tooth ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808701210
更新日期:2008-12-01 00:00:00
abstract::Because of the greater sensitivity of commonly used dental films near 40 kv and the inherently greater contrast between bone and other oral tissues that is achieved at lower energies than those conventionally used, a considerable reduction of radiation exposure can be obtained by the use of those quasimonochromatic ph...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550010801
更新日期:1976-01-01 00:00:00
abstract::The purpose of this work was to determine the influence of chemical food-simulating liquids on the wear of various commercial dental composite restoratives. In many cases, pre-conditioning the restoratives in these liquids for one week produced swelling of the polymer matrix and considerable surface damage. The result...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345850640111601
更新日期:1985-11-01 00:00:00
abstract::Samples of plaque and surface enamel were collected from 80 boys aged 14 years living in five communities in Ohio (USA). Mean (+/- SE) strontium concentrations in plaque were 1.43 +/- 0.18 micrograms/g (wet) and 12.34 +/- 1.63 micrograms/g (dry). For surface enamel, the mean concentration was 421 +/- 31 micrograms Sr/...
journal_title:Journal of dental research
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doi:10.1177/00220345850640121201
更新日期:1985-12-01 00:00:00
abstract::The synthesis of many polycarboxylic acids is reported. An account is given of their stability in aqueous solution and the properties of cements formed by their reaction with ion-leachable glasses. A copolymer of acrylic and itaconic acids was found to combine several favorable characteristics. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590060801
更新日期:1980-06-01 00:00:00
abstract::The dental phenolic medicaments, eugenol and guaiacol, are partly similar in chemical structure to capsaicin, the pungent constituent of chili peppers, which selectively activates sensory neurons via a specific receptor. We have previously demonstrated that these phenolic compounds show capsaicin-like action. In the p...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760040501
更新日期:1997-04-01 00:00:00
abstract::Dispersed salivary acini isolated from the rat submandibular gland by enzymatic digestion were used to study the effects of alpha-receptor stimulation on transmembrane transport of 36Cl. In the absence of secretagogue, the tracer accumulated in the cells in a time-dependent manner until a steady-state content of 6.8 +...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670030701
更新日期:1988-03-01 00:00:00
abstract::A search was made for expression of genes for proline-rich proteins (PRPs) and other salivary-type proteins, including statherin and histatins, in taste-bud tissues of mice and primates because of previous genetic findings in mice (Azen et al., 1986) that Prp and taste genes for certain bitter substances are either th...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345900690110401
更新日期:1990-11-01 00:00:00
abstract::As an approach for improving the outcome and predictability of periodontal regenerative therapies, we have focused on determining the responses of cells within the local environment to putative regenerative factors. This study examined the effects of bone morphogenetic protein-2 (BMP-2) on murine cementoblasts in vitr...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200106
更新日期:2003-01-01 00:00:00
abstract::Mastication as a mild but life-long exercise has been examined as a possibility for maintaining brain function in the elderly. Little is known, however, about the cerebral circulatory response during masticatory movement. The aim of this study was to develop a monitoring system for circulation dynamics during masticat...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510383692
更新日期:2011-01-01 00:00:00
abstract::Decisions to replace existing restorations are often based on clinical findings of margin discrepancies and other restoration defects. Previous studies have suggested that such findings do not correlate well with the actual presence of secondary caries, and that treatment should be deferred until caries is clinically ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720121301
更新日期:1993-12-01 00:00:00
abstract::A method of articulator comparison and a technique demonstrating the effects of three occlusal determinants were demonstrated and proved successful. The techniques used could be used in dental research circumstances and in dental schools as a means to study the determinants of occlusion. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550060601
更新日期:1976-11-01 00:00:00
abstract::The purpose of the study was to determine the exposure times needed to harden a light-activated composite cement through various thicknesses of porcelain. A negative exponential model was developed with which the relative hardness of a composite could be predicted from the product of the exposure time and the square r...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345890680030801
更新日期:1989-03-01 00:00:00
abstract::The objectives of the study were to describe the oral health status and treatment needs of the 5- to 6-year-old and 12-year-old children in Southern China; to describe the patterns of oral health behaviors, knowledge, and attitudes among the 12-year-olds; and to assess the effects of socio-behavioral factors on the 12...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345010800051501
更新日期:2001-05-01 00:00:00
abstract::Various etching methods are examined with respect to their ability to induce the surface nucleation and growth of fluorapatite from solutions of low, sustained supersaturation with respect to hydroxyapatite and fluorapatite. The constant composition kinetics method enables the rates of remineralization to be precisely...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345820610091301
更新日期:1982-09-01 00:00:00
abstract::A quantitative microprobe analysis was conducted on three commercial amalgams to determine the nature of the phases present. The presence of tin in the Ag-Hg phase (gamma1) was confirmed and Cu-3Sn was found in the original alloy particles. In the dispersant amalgam studied, little Sn-Hg phase (gamma-2) was found and ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::Four disclosant dyes were tested for antimicrobial activity against 27 oral reference strains and five non-oral human pathogens. Erythrosine and fluorescein inhibited most gram-positive and gram-negative organisms associated with dental plaque, and were bactericidal to selected strains. Fast green and brilliant blue d...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620071601
更新日期:1983-07-01 00:00:00
abstract::Based on the existing evidence supporting a state of chronic inflammation in chronic kidney disease (CKD), we hypothesized that periodontal infection may affect the systemic inflammatory status of a nationally representative CKD population as measured by serum C-reactive protein (CRP). We examined this hypothesis usin...
journal_title:Journal of dental research
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doi:10.1177/0022034511423394
更新日期:2011-12-01 00:00:00
abstract::Alendronate (ALN) is an antiresorptive agent widely used for the treatment of osteoporosis. Its suppressive effect on osteoclasts has been extensively studied. However, the effect of ALN on bone formation is not as clear as its effect on resorption. The objective was to determine the effect of short-term ALN on bone f...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515592867
更新日期:2015-09-01 00:00:00
abstract::Nitric oxide (.NO) modulates the activity of the endocrine system in the behavioral response to stress. The purpose of this study was to investigate the effect of restraining the body of an animal on expression of neuronal nitric oxide synthase (nNOS) in the paraventricular nucleus (PVN) of the hypothalamus, and the i...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910508400708
更新日期:2005-07-01 00:00:00
abstract::Medication-related osteonecrosis of the jaw (MRONJ), although initially believed to be exclusively associated with bisphosphonates, has been implicated in recent reports with additional drugs, especially the bone antiresorptive denosumab. The pathophysiology has not been fully elucidated, and no causal association bet...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034515572021
更新日期:2015-04-01 00:00:00
abstract::It is generally accepted that glass ionomers inhibit secondary caries in vivo, and data from in vitro studies support this effect. The aim of this review was a systematic assessment, from the literature, of clinical evidence for the ability of glass-ionomer restoratives to inhibit secondary caries at the restoration m...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345990780020101
更新日期:1999-02-01 00:00:00
abstract::The lack of a reliable bond test has hindered the elucidation of the mechanism for porcelain-metal bonding in dental systems, because a test capable of detecting differences among porcelain-metal bonds of various qualities is required before the reasons for these differences may be ascertained. A method was developed ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670020801
更新日期:1988-02-01 00:00:00
abstract::Bacteria attach to teeth and oral mucosal surfaces in a surprisingly selective manner, and attachment appears to be the first step in the colonization process. Attachment is thought to involve lectin-like and/or hydrophobic ligands, called adhesins, often present in bacterial surface appendages which interact with rec...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630030401
更新日期:1984-03-01 00:00:00
abstract::Cleidocranial dysplasia (CCD) is a skeletal dysplasia caused by heterozygous mutations of RUNX2, a gene that is essential for the mineralization of bone and tooth. We isolated primary dental pulp cells from a 10-y-old patient and tested their proliferative capacity, alkaline phosphatase activity, and ability to form m...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514566655
更新日期:2015-04-01 00:00:00