In vivo bioreactors for mandibular reconstruction.

abstract：:Periodontitis is a complex, multifactorial chronic disease involving continuous interactions among bacteria, host immune/inflammatory responses, and modifying genetic and environmental factors. More than any other cytokine family, the interleukin (IL)-1 family includes key signaling molecules that trigger and perpetua...

journal_title：Journal of dental research

authors： Papathanasiou E,Conti P,Carinci F,Lauritano D,Theoharides TC

更新日期：2020-12-01 00:00:00

abstract：:Inorganic polyphosphate [Poly(P)] is especially prevalent in osteoblasts. We tested the hypothesis that Poly(P) stimulates osteoblastic differentiation and polyphosphate metabolism for bone formation. The osteoblast-like cell line, MC 3T3-E1, was cultured with Poly(P), and gene expression was evaluated by real-time re...

journal_title：Journal of dental research

authors： Usui Y,Uematsu T,Uchihashi T,Takahashi M,Takahashi M,Ishizuka M,Doto R,Tanaka H,Komazaki Y,Osawa M,Yamada K,Yamaoka M,Furusawa K

更新日期：2010-05-01 00:00:00

abstract：:The tongue plays an important role in mastication and swallowing by its contact with the hard palate. Using an experimental palatal plate with 7 pressure sensors, and recording jaw movement using mandibular kinesiography, we assessed, in healthy subjects, the coordination of tongue and jaw movements during the entire ...

journal_title：Journal of dental research

authors： Hori K,Ono T,Nokubi T

更新日期：2006-02-01 00:00:00

abstract：:Recent functional animal studies have reported that the motor control of masticatory muscle function is bilaterally guided by both hemispheres, which may fundamentally differ from the cortical control of limb muscle function. In this study, we investigated whether unilateral cortical brain infarction induces different...

journal_title：Journal of dental research

authors： Kemppainen P,Waltimo A,Palomäki H,Salonen O,Könönen M,Kaste M

更新日期：1999-12-01 00:00:00

abstract：:In order for the role of parotid amylase in starch digestion in the gastro-intestinal tracts of diabetic rats to be clarified, this study investigated the effect of parotid-duct ligation on both amylase secretion from the parotid glands and pancreas into the gastro-intestinal tract and on starch digestion in the gastr...

journal_title：Journal of dental research

authors： Kurahashi M,Inomata K

更新日期：1989-09-01 00:00:00

abstract：:Epithelial-mesenchymal interactions are required for tooth formation. Bone morphogenetic protein 4 (Bmp4) is a crucial signaling molecule during this process. For better understanding of the role of the Bmp4 gene during tooth development, we studied the mechanisms that control its temporal and spatial expression durin...

journal_title：Journal of dental research

authors： Feng JQ,Zhang J,Tan X,Lu Y,Guo D,Harris SE

更新日期：2002-01-01 00:00:00

abstract：:Resin-bonded bridges may replace missing teeth and act as splints in periodontal treatment. The objective of this study was to investigate the etch pattern after electrolytic etching of selected Co-Cr alloys in hydrochloric acid and to assess the changes in alloy composition after different etching times. The alloys i...

journal_title：Journal of dental research

authors： Ekstrand K,Ruyter IE

更新日期：1987-09-01 00:00:00

abstract：:We examined 102 children born and reared in an area of rural Kenya with 2 ppm fluoride in the drinking water for dental fluorosis, using the index developed by Thylstrup and Fejerskov (1978). The prevalence of dental fluorosis was 100%, 92% of all teeth exhibited a TFI score of 4 or higher, and 50% of the children had...

journal_title：Journal of dental research

authors： Manji F,Baelum V,Fejerskov O

更新日期：1986-05-01 00:00:00

abstract：:To understand the role of betel quid (BQ) in the pathogenesis of oral submucous fibrosis (OSF) and oral cancer, we used DNA damage, cytotoxicity, and cell proliferation assays to study the pathobiological effects of aqueous extracts of three BQ constituents [betel nut (Areca catechu, BN), inflorescence of Piper betle ...

journal_title：Journal of dental research

authors： Jeng JH,Kuo ML,Hahn LJ,Kuo MY

更新日期：1994-05-01 00:00:00

abstract：:Smoking is a major risk of periodontal diseases. At the site of first contact, the gingiva is exposed to aromatic amines and polycyclic hydrocarbons. These are metabolized by the N-acetyltransferases (NAT), leading to local detoxification and/or activation reactions contributing to the risk of periodontal destruction ...

journal_title：Journal of dental research

authors： Meisel P,Giebel J,Peters M,Foerster K,Cascorbi I,Wulff K,Fanghaenel J,Kocher T

更新日期：2002-05-01 00:00:00

abstract：:The cacao bean husk has been shown to possess two types of cariostatic substances, one showing anti-glucosyltransferase (GTF) activity and the other antibacterial activity, and to inhibit experimental dental caries in rats infected with mutans streptococci. In the present study, chromatographic purification revealed h...

journal_title：Journal of dental research

authors： Osawa K,Miyazaki K,Shimura S,Okuda J,Matsumoto M,Ooshima T

更新日期：2001-11-01 00:00:00

abstract：:Our long-term objective is to devise methods to improve osteotomy site preparation and, in doing so, facilitate implant osseointegration. As a first step in this process, we developed a standardized oral osteotomy model in ovariectomized rats. There were 2 unique features to this model: first, the rats exhibited an os...

journal_title：Journal of dental research

authors： Chen CH,Pei X,Tulu US,Aghvami M,Chen CT,Gaudillière D,Arioka M,Maghazeh Moghim M,Bahat O,Kolinski M,Crosby TR,Felderhoff A,Brunski JB,Helms JA

更新日期：2018-04-01 00:00:00

abstract：:Teas varying in fluoride and tannin concentration were evaluated in rats for anticariogenic activity. There was a direct correlation between fluoride in tea and the inhibition of sulcal caries in rats, whereas no relationship was observed between tannin and this type of lesion. Teas also had a significant effect on ca...

journal_title：Journal of dental research

authors： Rosen S,Elvin-Lewis M,Beck FM,Beck EX

更新日期：1984-05-01 00:00:00

abstract：:Vietnamese immigrant and Norwegian children, matched according to caries experience, age, and sex, were compared with respect to S. mutans in dental plaque and in saliva. Regardless of ethnic group, S. mutans prevalence was highest in plaque over caries lesions and from fissures, and lowest in plaque from smooth surfa...

journal_title：Journal of dental research

authors： Scheie AA,Selikowitz HS,Arneberg P

更新日期：1984-12-01 00:00:00

abstract：:A radiotracer technique was used to study silver and gold diffusion into dental porcelain under experimental conditions close to the real conditions in prosthetic laboratories for porcelain bakes. It was clearly shown that these non-oxidizable elements were able to diffuse into the ceramic as well as oxidizable ones. ...

journal_title：Journal of dental research

authors： Moya F,Payan J,Bernardini J,Moya EG

更新日期：1987-12-01 00:00:00

abstract：:Amelogenin gene organization varies from 6 exons (1,2,3,5,6,7) in amphibians and sauropsids to 10 in rodents. The additional exons are exons 4, 8, 9, and "4b", the latter being as yet unidentified in AMELX transcripts. To learn more about the evolutionary origin of these exons, we used an in silico approach to find th...

journal_title：Journal of dental research

authors： Sire JY,Huang Y,Li W,Delgado S,Goldberg M,Denbesten PK

更新日期：2012-01-01 00:00:00

abstract：:The acquired enamel pellicle is an oral, fluid-derived protein layer that forms on the tooth surface. It is a biologically and clinically important integument that protects teeth against enamel demineralization, and abrasion. Tooth surfaces are exposed to different proteinaceous microenvironments depending on the enam...

journal_title：Journal of dental research

authors： Heller D,Helmerhorst EJ,Oppenheim FG

更新日期：2017-04-01 00:00:00

abstract：:In this study, the differences in lesion remineralization and fluoride uptake after brushing with a 300 ppm F or a 1000 ppm F dentifrice (as NaF) were investigated. Twenty volunteers with partial dentures in their lower jaws were divided into two groups. Bovine enamel slabs with artificial lesions were mounted in the ...

journal_title：Journal of dental research

authors： De Kloet HJ,Exterkate RA,Rempt HE,Ten Cate JM

更新日期：1986-12-01 00:00:00

abstract：:During orofacial tissue development, the anterior and posterior regions of the Meckel's cartilage undergo mineralization, while the middle region undergoes degeneration. Despite the interesting and particular phenomena, the mechanisms that regulate the different fates of Meckel's cartilage, including the effects of bi...

journal_title：Journal of dental research

authors： Farahat M,Kazi GAS,Hara ES,Matsumoto T

更新日期：2021-02-01 00:00:00

abstract：:A plaque growth chamber was developed for long-term growth of five separate plaques from the same plaque or saliva sample under identical conditions of temperature and gas phase. Reagent addition and growth conditions for each plaque could be independently controlled, and each was accessible for sequential sampling an...

journal_title：Journal of dental research

authors： Sissons CH,Cutress TW,Hoffman MP,Wakefield JS

更新日期：1991-11-01 00:00:00

abstract：:The main purpose of this paper is to review the various methods used for evaluation of fluoride retention in saliva, plaque, and enamel following application of topical anti-caries treatments such as F dentifrices and F mouthwashes. Such methods monitor delivery of fluoride to the site of action, the mouth, and so can...

journal_title：Journal of dental research

authors： Duckworth RM,Gilbert RJ

更新日期：1992-04-01 00:00:00

abstract：:Periodontal disease is a bacterial infection that results in inflammatory destruction of tissues that support the teeth, including connective tissue and bone. In this study, we report that transgenic mice that overexpress the 17-kDa form of IL-1alpha in the basal layer of oral mucosal epithelium develop a syndrome tha...

journal_title：Journal of dental research

authors： Dayan S,Stashenko P,Niederman R,Kupper TS

更新日期：2004-10-01 00:00:00

abstract：:Epstein-Barr virus (EBV), in addition to its transforming properties, contributes to the pathogenesis of several inflammatory diseases. Here, we investigated its involvement in oral lichen planus (OLP), a common autoimmune-like disease of unknown etiopathogenesis that can display a malignant potential. EBV-infected ce...

journal_title：Journal of dental research

authors： Raybaud H,Olivieri CV,Lupi-Pegurier L,Pagnotta S,Marsault R,Cardot-Leccia N,Doglio A

更新日期：2018-12-01 00:00:00

abstract：:Nearly 100% of patients experience trauma to the trigeminal nerve during orthognathic surgery, impairing sensation and sensory function on the face. In a recent randomized clinical trial, people who performed sensory re-training exercises reported less difficulty related to residual numbness and decreased lip sensitiv...

journal_title：Journal of dental research

authors： Essick GK,Phillips C,Zuniga J

更新日期：2007-06-01 00:00:00

abstract：:Van der Woude syndrome (VWS) is an autosomal-dominant oral facial disorder. To find a gene mutation in a Japanese family using fingernail DNA samples, we performed this study. We hypothesized that a gene mutation in IRF6 might be involved in VWS, and that fingernail DNA samples may be valuable for detecting such mutat...

journal_title：Journal of dental research

authors： Matsuzawa N,Shimozato K,Natsume N,Niikawa N,Yoshiura K

更新日期：2006-12-01 00:00:00

abstract：:Mechanical removal of oral biofilms is ubiquitously accepted as the best way to prevent caries and periodontal diseases. Removal effectiveness strongly depends on biofilm strength. To investigate the influence of hydrodynamics on oral biofilm strength, we grew single- and multi-species biofilms of Streptococcus oralis...

journal_title：Journal of dental research

authors： Paramonova E,Kalmykowa OJ,van der Mei HC,Busscher HJ,Sharma PK

更新日期：2009-10-01 00:00:00

abstract：:The aim of the present study was to describe the patterns of dental fluorosis in the primary and the permanent dentition of children born and reared in two different fluoridated areas, one in which powdered milk suspended in tap water was commonly used (Narssaq, Greenland: 1.1 ppm fluoride in the water) and one in whi...

journal_title：Journal of dental research

authors： Larsen MJ,Senderovitz F,Kirkegaard E,Poulsen S,Fejerskov O

更新日期：1988-05-01 00:00:00

abstract：:Cardiovascular disease is a common cause of morbidity and premature mortality. Cardiovascular disease can be prevented when risk factors are identified early. Calcified carotid artery atheromas (CCAAs), detected in panoramic radiographs, and periodontitis have both been associated with increased risk of cardiovascular...

journal_title：Journal of dental research

authors： Gustafsson N,Ahlqvist J,Näslund U,Buhlin K,Gustafsson A,Kjellström B,Klinge B,Rydén L,Levring Jäghagen E

更新日期：2020-01-01 00:00:00

abstract：:Frequent consumption of cariogenic foods and bacterial infection are risk factors for early childhood caries (ECC). This study hypothesized that a short diet survey focused on frequency of foods, categorized by putative cariogenicity, would differentiate severe ECC (S-ECC) from caries-free children. Children's diets w...

journal_title：Journal of dental research

authors： Palmer CA,Kent R Jr,Loo CY,Hughes CV,Stutius E,Pradhan N,Dahlan M,Kanasi E,Arevalo Vasquez SS,Tanner AC

更新日期：2010-11-01 00:00:00

abstract：:Better understanding of dental caries and other oral conditions has guided new strategies to prevent disease and manage its consequences at individual and public health levels. This article discusses advances in prevention and minimal intervention dentistry over the last century by focusing on some milestones within s...

journal_title：Journal of dental research

authors： Innes NPT,Chu CH,Fontana M,Lo ECM,Thomson WM,Uribe S,Heiland M,Jepsen S,Schwendicke F

更新日期：2019-06-01 00:00:00