Abstract:
:Pieces of fresh rat incisor enamel were extracted with various buffer solutions and prepared for electron microscopy. I observed partial or complete removal of organic constituents, shrinkage of rods and interrods, separation of stippled material from the enamel, and partial decalcification. The results modify the conclusions of earlier biochemical work and point out the need for a closer correlation of biochemical and morphological approaches.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Kallenbach Esubject
Has Abstractpub_date
1982-12-01 00:00:00pages
1515-23eissn
0022-0345issn
1544-0591journal_volume
Spec Nopub_type
杂志文章abstract::Extracellular matrix (ECM) mineralization is regulated by mineral ion availability, proteins, and other molecular determinants. To investigate protein regulation of mineralization in tooth dentin and cementum, and in alveolar bone, we expressed matrix Gla protein (MGP) ectopically in bones and teeth in mice, using an ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700907
更新日期:2008-09-01 00:00:00
abstract::Adhesion of epithelium to the extracellular matrix is crucial for the maintenance of systemic and oral health. In the oral cavity, teeth or artificial dental implants penetrate the soft tissue of the gingiva. In this interface, gingival soft tissue needs to be well attached via the epithelial seal to the tooth or impl...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034511402207
更新日期:2011-12-01 00:00:00
abstract::Although certain bacterial species appear to be risk factors for pain due to odontogenic infections, comparatively little is known about the potential mechanisms mediating this effect. In this study, we tested the hypothesis that trigeminal nociceptive neurons express the TLR4 or CD14 receptors, thus enabling sensory ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500108
更新日期:2006-01-01 00:00:00
abstract::The effect of a topical fluoride regimen consisting of a four-minute pre-treatment with a saturated dicalcium phosphate dihydrate (DCPD) solution followed by a four-minute application of APF was compared with that of a four-minute application of APF alone with respect to the deposition of fluoride in enamel in an apat...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650030201
更新日期:1986-03-01 00:00:00
abstract::It is claimed that dental fluorosis in both deciduous and permanent teeth is increasing in fluoridated and non-fluoridated communities. What is unclear is whether fluoride-induced enamel opacities in the deciduous dentition are associated with the subsequent appearance of enamel defects in the permanent dentition. The...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750040301
更新日期:1996-04-01 00:00:00
abstract::Periodontitis is increasingly associated with increased risk of cardiovascular and other systemic diseases. The Gram-negative anaerobe, Porphyromonas gingivalis, is a key periodontal pathogen, and several lines of evidence link the presence of this bacterium in the circulation with vascular disease. The outer membrane...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520943187
更新日期:2020-12-01 00:00:00
abstract::To determine the 'hard palate representing' area in the primary somatosensory cortex, we recorded somatosensory-evoked magnetic fields from the cortex in ten healthy volunteers, using magnetoencephalography. Following electrical stimulation of 3 sites on the hard palate (the first and third transverse palatine ridges,...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708600313
更新日期:2007-03-01 00:00:00
abstract::An adhesive opaque resin for veneering on cast metal was developed with 4-methacryloxyethyl trimellitate anhydride and poly (methyl methacrylate)-coated titanium dioxide prepared by aqueous phase polymerization. The opaque resin was a modified 4-META/MMA-TBB resin. The powder consisted of 20% of the encapsulated mater...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670010501
更新日期:1988-01-01 00:00:00
abstract::In this study, we analyzed the influence of prosthetic abutment height on marginal bone loss (MBL) around implants in the posterior maxilla. In this retrospective cohort study, the radiographically determined MBL was related to the height of the abutments of internal conical connection implants at 6 and 18 months post...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513519800
更新日期:2014-07-01 00:00:00
abstract::The Triggering Receptor Expressed on Myeloid cells 1 (TREM-1) is a cell-surface receptor of the immunoglobulin superfamily, involved in the propagation of the inflammatory response to bacterial challenge. Soluble (s)TREM-1 is released from the cell surface during the course of infection and is a useful inflammatory bi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034512470691
更新日期:2013-02-01 00:00:00
abstract::Composite resin restorations in cavities are generally associated with the development of a contraction gap during the first minutes after insertion. Enamel-Bond-Concise composite restoration were placed on both approximal sides of extracted pre-molars. The cervical walls of all cavities extended beyond the enamel-cem...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630051501
更新日期:1984-05-01 00:00:00
abstract::Cytotoxicity of fine cut amalgam was persistent until 24 hours after trituration in vitro, whereas cytotoxicity of spherical amalgam diminished more quickly. Increasing mercury content in spherical amalgam increased cytotoxicity. Possible reactions for the diminution of cytotoxicity of amalgams with time are discussed...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::The feasibility of immunizing monkeys with enzymes from oral streptococci in an attempt to reduce dental caries was investigated. Forty rhesus monkeys, Macaca mulatta, were used. Cariogenic streptococci, S mutans, were implanted into all the monkeys' mouths. There was no pathological effect resulting from immunization...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560123001
更新日期:1977-12-01 00:00:00
abstract::Branching morphogenesis is essential for the formation of salivary glands, kidneys, lungs, and many other organs during development, but the mechanisms underlying this process are not adequately understood. Microarray and other gene expression methods have been powerful approaches for identifying candidate genes that ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034511429346
更新日期:2012-02-01 00:00:00
abstract::Amelogenin and ameloblastin, the major enamel matrix proteins, are important for enamel mineralization. To identify their synergistic roles in enamel development, we generated Amel X(-/-)/Ambn(-/-) mice. These mice showed additional enamel defects in comparison with Amel X(-/-) or Ambn(-/-) mice. In 7-day-old Amel X(-...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509334749
更新日期:2009-04-01 00:00:00
abstract::Although the occlusal vertical dimension (OVD) is strictly controlled, the neuronal mechanism of its regulation is still unclear. We hypothesize that neurons in the trigeminal mesencephalic nucleus (MesV) play an important role in the regulation of the OVD, because the MesV receives the projection from jaw-closing mus...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200715
更新日期:2003-07-01 00:00:00
abstract::This study was undertaken in order to correlate the immune status of persons with various types of immune dysfunctions with the incidence of dental caries. Preliminary data on caries experience and the microbial composition of plaque in these individuals are presented. The findings suggest that persons with immunoglob...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560030201
更新日期:1977-03-01 00:00:00
abstract::The effect of different doses of polyadenylic and polyuridylic acids (poly A:U) was studied in control rats and in rats exposed to hypoxia. In the control rats, administration of different doses of poly A:U did not change the thickness of the epiphyseal plate or increase the incorporation of 3H-phenylalanine as judged...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550041701
更新日期:1976-07-01 00:00:00
abstract::Relative glycogen synthetic abilities of resting cells of fresh clinical isolates of Actinomyces viscosus and Actinomyces naeslundii originating from dental plaque samples over root surface caries lesions and non-carious sites were studied under anaerobic conditions at a constant pH of 7.0, with U-(14C)-glucose used a...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650060701
更新日期:1986-06-01 00:00:00
abstract::We previously demonstrated that an anti-caries DNA vaccine intranasally administered with recombinant flagellin protein as a mucosal adjuvant enhanced salivary IgA response and conferred better protection against caries. However, the relatively weak immunogenicity of DNA vaccines and the necessity for a large quantity...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034512457684
更新日期:2012-10-01 00:00:00
abstract::This study has identified and characterized class II (Ia) antigen-expressing cells in the normal rat incisor pulp by immunohistochemistry and flow cytometry. Two types of Ia-expressing cells occurred: one with a pronounced dendritic appearance located primarily in the periphery of the pulp, and one with morphological ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670100301
更新日期:1988-10-01 00:00:00
abstract::Sense of coherence (SOC) has been related to oral health behaviors and oral-health-related quality of life (OHRQoL) in observational studies. This cluster-randomized trial aimed to test the effect of an intervention to enhance SOC on OHRQoL in children. Twelve primary schools were randomly allocated to intervention an...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/0022034512459757
更新日期:2013-01-01 00:00:00
abstract::Repulsive magnetic appliances can intrude posterior teeth, but create a lateral shift of the mandible and also decrease in force as the mouth opens. To model their optimal use, the 3-D spatial force/displacement (F/D) and moment/displacement (M/D) diagrams of four magnetic repulsive appliances in diverse overlapping a...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345940730010901
更新日期:1994-01-01 00:00:00
abstract::Using glycoproteins and milk oligosaccharides as substrate acceptors, we demonstrated at least two fucosyltransferases in human parotid saliva. One enzyme transferred L-fucose from GDP-fucose to the C-3 position of N-acetylglucosamine or glucose residue of oligosaccharide chains, and the other transferred to the C-4 p...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620070701
更新日期:1983-07-01 00:00:00
abstract::Caregivers' health literacy has emerged as an important determinant of young children's health care and outcomes. We examined the hypothesis that caregivers' health literacy influences children's oral-health-care-related expenditures. This was a prospective cohort study of 1,132 child/caregiver dyads (children's mean ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513484335
更新日期:2013-07-01 00:00:00
abstract::This study investigated the association between caries status and sealant need at a prior survey and subsequent sealant use in a Medicaid program. Clinical data from a 1986-87 statewide epidemiological survey (N = 8026) representative of North Carolina (NC) schoolchildren (grades K-12) were linked with all NC Medicaid...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760120901
更新日期:1997-12-01 00:00:00
abstract::Modulation of the phosphoinositide signal transduction pathway by arachidonic acid (AA) in collagenase-dispersed rat submandibular acinar cells was investigated. The muscarinic agonist, carbachol, stimulated PIP2 hydrolysis and the generation of IP3 to five-fold the control levels. This response was inhibited by 75% o...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345920710080101
更新日期:1992-08-01 00:00:00
abstract::The effects of Escherichia coli endotoxin upon mouse L929 cell proliferation, DNA synthesis, protein synthesis, and proline incorporation were determined. It was found that a level of endotoxin which inhibited cell proliferation prompted a similar inhibition of DNA synthesis and overall cell protein synthesis. In cont...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580061301
更新日期:1979-06-01 00:00:00
abstract::Sealants are highly effective in preventing dental caries in the pits and fissures of teeth when applied by trained operators in clinical trials and public health programs. The effectiveness of fissure sealants when applied in dental practices is still not known. The purpose of this longitudinal study was to evaluate ...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/00220345950740091301
更新日期:1995-09-01 00:00:00
abstract::In the past two decades, accumulated evidence has clearly demonstrated the inhibitory effects of laser irradiation on enamel demineralization, but the exact mechanisms of these effects remain unclear. The purpose of this study was to investigate the effects of low-energy CO2 laser irradiation on demineralization of bo...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790091401
更新日期:2000-09-01 00:00:00