Abstract:
:This study has identified and characterized class II (Ia) antigen-expressing cells in the normal rat incisor pulp by immunohistochemistry and flow cytometry. Two types of Ia-expressing cells occurred: one with a pronounced dendritic appearance located primarily in the periphery of the pulp, and one with morphological characteristics similar to those of macrophages. The latter cells were mainly observed in the central portion of the pulp. A numerical ratio of 1:4 was established between the two cell types. The existence of Ia-expressing cells suggests an inherent capacity of the pulp to process and present foreign antigens.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Jontell M,Bergenholtz G,Scheynius A,Ambrose Wdoi
10.1177/00220345880670100301subject
Has Abstractpub_date
1988-10-01 00:00:00pages
1263-6issue
10eissn
0022-0345issn
1544-0591journal_volume
67pub_type
杂志文章abstract::A detailed understanding of the complexity of root canal systems is imperative to ensure successful root canal preparation. The aim of this study was to evaluate the potential and accuracy of a three-dimensional, non-destructive technique for detailing root canal geometry by means of high-resolution tomography. The an...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790060901
更新日期:2000-06-01 00:00:00
abstract::It is claimed that dental fluorosis in both deciduous and permanent teeth is increasing in fluoridated and non-fluoridated communities. What is unclear is whether fluoride-induced enamel opacities in the deciduous dentition are associated with the subsequent appearance of enamel defects in the permanent dentition. The...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750040301
更新日期:1996-04-01 00:00:00
abstract::The work described considers the effects on calcified tissues of those concentrations of fluoride which are not overtly cyto-toxic, i.e., in the general region of up to 1-2 mumol/L. Plasma fluoride concentrations or those of the cellular environment are considered rather than dietary levels. The effect of fluoride ion...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345900690S134
更新日期:1990-02-01 00:00:00
abstract::Rotational freedom of the implant-abutment connection influences its screw joint stability; for optimization, influential factors need to be evaluated based on a previously developed closed formula. The underlying hypothesis is that the manufacturing tolerances, geometric pattern, and dimensions of the index do not in...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509341243
更新日期:2009-08-01 00:00:00
abstract::The cariostatic benefit from water fluoridation is indisputable, but the knowledge of possible adverse effects on bone and fracture risk due to fluoride exposure is ambiguous. The association between long-term (chronic) drinking water fluoride exposure and hip fracture (ICD-7-9: '820' and ICD-10: 'S72.0-S72.2') was as...
journal_title:Journal of dental research
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doi:10.1177/0022034513506443
更新日期:2013-11-01 00:00:00
abstract::Extracellular microcapsules have been demonstrated on cells of most serotypes of Streptococcus mutans by electron microscopy, using bacterial strains of the various serotypes and peroxidase labeled or unlabeled immune serum. A correlation was noted between the amount of capsular substance on the strains of S mutans ex...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560021101
更新日期:1977-02-01 00:00:00
abstract::Dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) are expressed as a single mRNA transcript coding for a large precursor protein termed dentin sialophosphoprotein (DSPP). DSP, DPP, and DSPP have been considered to be tooth-specific. To test for the expression of the dspp gene in bone, we performed Western immu...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910208100607
更新日期:2002-06-01 00:00:00
abstract::Bacteria attach to teeth and oral mucosal surfaces in a surprisingly selective manner, and attachment appears to be the first step in the colonization process. Attachment is thought to involve lectin-like and/or hydrophobic ligands, called adhesins, often present in bacterial surface appendages which interact with rec...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630030401
更新日期:1984-03-01 00:00:00
abstract::In this study, we first investigated the expressions of Jagged1, Notch2, the receptor activator of nuclear factor-kappa B ligand (RANKL), and interleukin (IL)-6 in areas of root resorption during experimental tooth movement in rats in vivo. We then assessed the effects of compression force (CF) with or without GSI (an...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514555364
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abstract::Adhesive bonding of resins to dentin surfaces requires the removal of the layer of debris caused by the cutting. Certain isotonic acidic solutions can do this rapidly. Five solutions were evaluated using cell cultures and pulp studies in monkeys. At concentrations above 10%, each solution caused the cultured human epi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345820610081001
更新日期:1982-08-01 00:00:00
abstract::Patients suffering from temporomandibular dysfunction exhibit clinical findings such as fatigue, painful muscles, and muscles that are tender to palpation, not only in the temporomandibular area, but also in the neck/shoulder region. The mechanisms behind this are not known, although previous studies of similar spread...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790101401
更新日期:2000-10-01 00:00:00
abstract::The present study was conducted to investigate the role of proteolysis by matrix metalloproteinase 20 (MMP20) in regulating the initial formation of the enamel mineral structure during the secretory stage of amelogenesis, utilizing Mmp20-null mice that lack this essential protease. Ultrathin sagittal sections of maxil...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034518823537
更新日期:2019-04-01 00:00:00
abstract::Evidence that dental status affects diet is equivocal. The hypothesis of this study was that diet was affected by dental status. The objective was to assess the relationship between numbers of teeth and diet and nutritional status in US adult civilians without prostheses. We examined 6985 NHANES (1988-1994) participan...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708601206
更新日期:2007-12-01 00:00:00
abstract::Stable fluoride-resistant mutants of Streptococcus mutans GS-5 were isolated on Todd-Hewitt agar by a step-wise selection procedure. Resistance is defined here as the ability to form colonies in 48 hr. First-step mutants demonstrated six different levels of resistance, ranging from 400 to 1000 micrograms/mL sodium flu...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660101701
更新日期:1987-10-01 00:00:00
abstract::As an approach for improving the outcome and predictability of periodontal regenerative therapies, we have focused on determining the responses of cells within the local environment to putative regenerative factors. This study examined the effects of bone morphogenetic protein-2 (BMP-2) on murine cementoblasts in vitr...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200106
更新日期:2003-01-01 00:00:00
abstract::Degradation of dentin matrix components within caries dentin has been correlated with the activity of host-derived proteases, such as matrix metalloproteases (MMPs) and cysteine cathepsins (CTs). Since this relationship has not been fully established, we hypothesized that the abundance of MMPs and CTs in caries-affect...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513516979
更新日期:2014-03-01 00:00:00
abstract::An in vitro model has been developed for measurement of initial attachment of 3H-labeled human gingival fibroblasts (HGF) and periodontal ligament cells (HPDL cells) to sieved dentin powder. Reproducible attachment was obtained and was closely related to the number of plated cells, the amount of dentin powder, the tem...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720030901
更新日期:1993-03-01 00:00:00
abstract::In a standard periodontal treatment strategy with consecutive root planings (per quadrant at a one- to two-week interval), re-infection of a disinfected area might occur before completion of the treatment. This study examines, both clinically and microbiologically, whether a full-mouth disinfection within 24 hours sig...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/00220345950740080501
更新日期:1995-08-01 00:00:00
abstract::Short-chain carboxylic acids (e.g., lactic acid, propionic acid, butyric acid) are metabolic by-products of bacterial metabolism which can accumulate in the gingival crevice. It is of no small consequence, therefore, that 1- to 5-mM concentrations of these acids exhibit significant biological activity, including the a...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760010801
更新日期:1997-01-01 00:00:00
abstract::Autoimmune responses to heat-shock protein 60 (HSP60) contribute to the progression of atherosclerosis, whereas immunization with HSP60 may induce atheroprotective responses. We assessed the capacity of an atheroprotective vaccine that targeted a recombinant HSP60 from Porphyromonas gingivalis (rGroEL) to induce a pro...
journal_title:Journal of dental research
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更新日期:2014-04-01 00:00:00
abstract::The effect of chronic fluoride (F) exposure from the drinking water on parameters related to glucose homeostasis was investigated. Wistar rats were randomly distributed into 2 groups (diabetic [D] and nondiabetic [ND]; n = 54 each). In D, diabetes was induced with streptozotocin. Each group was further divided into 3 ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515581186
更新日期:2015-07-01 00:00:00
abstract::Pulpal blood flow was determined in 32 dogs ranging in age from 6 weeks to 18 months by the isotope fractionation method incorporating diffusible and nondiffusible tracers. Dogs were placed into selected age groups by the developmental status of the canine teeth. For the teeth sampled, the maxillary first, second, and...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560102601
更新日期:1977-10-01 00:00:00
abstract::The composition of the degradable glasses used in commercial dental glass-ionomer cements determines their leaching behavior and hence the properties of the cement. The objective of the present study was to assess if the composition and leaching in acetic acid solutions are reflected in the x-ray diffraction character...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345010800081601
更新日期:2001-08-01 00:00:00
abstract::Local anesthetic agents may be classified according to their intrinsic anesthetic potency and duration of activity. Procaine and chloroprocaine are relatively weak, short-acting drugs. Lidocaine, mepivacaine, and prilocaine represent agents of intermediate potency and duration of action. Tetracaine, bupivacaine, and e...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600080903
更新日期:1981-08-01 00:00:00
abstract::Mixtures containing two bacterial species were analyzed using flow cytometric techniques. Light scattering characteristics of Streptococcus mutans and Actinomyces viscosus show unique profiles for pure cultures. However, the light scatter analysis of a mixture containing these two species demonstrates overlapping near...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630080501
更新日期:1984-08-01 00:00:00
abstract::Two independent cross-over studies investigated the possibility of enhanced early enamel lesion remineralization with the use of chewing gum. The first study involved a sorbitol-containing chewing gum, and the second, which had an identical protocol, tested a sucrose-containing chewing gum. In each study, 12 volunteer...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/00220345920710120801
更新日期:1992-12-01 00:00:00
abstract::Mandibular prognathism is a common dentofacial phenotype with a substantial genetic component; however, few susceptibility loci have been mapped. Ethnicity is a risk factor for mandibular prognathism, and a relatively high prevalence is observed in Asian populations. The hypothesis of this study suggested that a speci...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510382546
更新日期:2011-01-01 00:00:00
abstract::The ability of adhesive resins to restore the physical properties of demineralized dentin has not been well-documented. The unfilled resins that are used for adhesion have relatively low moduli of elasticity and limited ability to increase dentin stiffness, although they may increase the ultimate tensile strength of d...
journal_title:Journal of dental research
pub_type: 杂志文章
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更新日期:1995-04-01 00:00:00
abstract::The aim of the present study was to describe the patterns of dental fluorosis in the primary and the permanent dentition of children born and reared in two different fluoridated areas, one in which powdered milk suspended in tap water was commonly used (Narssaq, Greenland: 1.1 ppm fluoride in the water) and one in whi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670050501
更新日期:1988-05-01 00:00:00
abstract::Previous studies have clearly established the down-regulating effect of a sucrose-rich diet on primary dentinogenesis in rat molars. Earlier observation of the negative effect of a high-sucrose diet on a parotid function involved in the control of intradentinal solute movement led us to hypothesize that parotid gland ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910208100407
更新日期:2002-04-01 00:00:00