The expression of dentin sialophosphoprotein gene in bone.

Abstract:

:Dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) are expressed as a single mRNA transcript coding for a large precursor protein termed dentin sialophosphoprotein (DSPP). DSP, DPP, and DSPP have been considered to be tooth-specific. To test for the expression of the dspp gene in bone, we performed Western immunoblots and reverse-transcription polymerase chain-reaction (RT-PCR). With Western immunoblots, we detected DSP in the Gdm/EDTA extracts of rat long bone, at a level of about 1/400 of that in dentin. Using RT-PCR, we detected DSPP mRNA in mouse calvaria. Similar to Western immunoblots, the results of RT-PCR indicated that the dspp gene is expressed at a lower level in bone than in dentin and odontoblasts. Analysis of the data shows that DSPP is not a tooth-specific protein, and that dramatically different regulatory mechanisms governing DSPP expression are involved in the bone and dentin.

journal_name

J Dent Res

authors

Qin C,Brunn JC,Cadena E,Ridall A,Tsujigiwa H,Nagatsuka H,Nagai N,Butler WT

doi

10.1177/154405910208100607

keywords:

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

392-4

issue

6

eissn

0022-0345

issn

1544-0591

journal_volume

81

pub_type

杂志文章
  • Formation of differentiated tissues in vivo by periodontal cell populations cultured in vitro.

    abstract::The periodontium contains heterogeneous mesenchymal cell populations with various differentiation potentials. The capacity of these cells for tissue formation as well as the origin of their precursors are still not entirely defined. In this study, cells originating from different periodontal tissues were cultured in v...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345950740051201

    authors: Lang H,Schüler N,Arnhold S,Nolden R,Mertens T

    更新日期:1995-05-01 00:00:00

  • Topical Fluoride to Prevent Root Caries: Systematic Review with Network Meta-analysis.

    abstract::The aim of this systematic review and network meta-analysis was to summarize the direct and indirect clinical evidence on the effectiveness of professionally applied and self-applied topical fluorides in preventing dental root caries. Controlled clinical trials with any follow-up duration were included. MEDLINE, PubMe...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034520906384

    authors: Zhang J,Sardana D,Li KY,Leung KCM,Lo ECM

    更新日期:2020-05-01 00:00:00

  • Association of gingival crevicular fluid aspartate aminotransferase levels with histopathology during ligature-induced periodontitis in the beagle dog.

    abstract::Previous investigations have shown a clear association between the presence of the enzyme aspartate aminotransferase (AST) in gingival crevicular fluid (GCF) and clinical evidence of periodontal disease in humans, as well as in the beagle dog model. This paper describes a 26-week study that uses the beagle dog model o...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345910700061501

    authors: Cohen RL,Alves ME,Crawford JM,McSwiggin T,Chambers DA

    更新日期:1991-06-01 00:00:00

  • Anti-biofilm effect of dental adhesive with cationic monomer.

    abstract::The incorporation of polymerizable cationic monomers has been attempted to generate dental resinous materials with antibacterial activity. This study tested the hypothesis that a dental adhesive containing a cationic monomer, methacryloxylethyl cetyl dimethyl ammonium chloride (DMAE-CB), would influence biofilm format...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034509334499

    authors: Li F,Chai ZG,Sun MN,Wang F,Ma S,Zhang L,Fang M,Chen JH

    更新日期:2009-04-01 00:00:00

  • Survival and Complications of Single Dental Implants in the Edentulous Mandible Following Immediate or Delayed Loading: A Randomized Controlled Clinical Trial.

    abstract::It was the aim of this 24-mo randomized controlled clinical trial to investigate whether the survival of a single median implant placed in the edentulous mandible to retain a complete denture is not compromised by immediate loading. Secondary outcomes were differences in prosthetic complications between the loading pr...

    journal_title:Journal of dental research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1177/0022034517736063

    authors: Kern M,Att W,Fritzer E,Kappel S,Luthardt RG,Mundt T,Reissmann DR,Rädel M,Stiesch M,Wolfart S,Passia N

    更新日期:2018-02-01 00:00:00

  • Characteristics of mandibular masticatory movement in young and elderly dentate subjects.

    abstract::Dimensions and velocity of mandibular movement are important variables in the evaluation of masticatory and speech patterns. However, little information is available concerning elderly dentates and their oral motor function and behavior. Double recordings of a chewing period, from start to swallowing, were performed i...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345900690021101

    authors: Karlsson S,Carlsson GE

    更新日期:1990-02-01 00:00:00

  • Periodontal breakdown in the Dmp1 null mouse model of hypophosphatemic rickets.

    abstract::Dentin Matrix Protein 1 (DMP1) is highly expressed in alveolar bone and cementum, which are important components of the periodontium. Therefore, we hypothesized that Dmp1 is critical for the integrity of the periodontium, and that deletion may lead to increased susceptibility to disease. An early-onset periodontal def...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910808700708

    authors: Ye L,Zhang S,Ke H,Bonewald LF,Feng JQ

    更新日期:2008-07-01 00:00:00

  • Evidence of sex-specific differences in masticatory jaw movement patterns.

    abstract::The complexity of human oral functional movements has not been studied in detail quantitatively, and only recently have studies begun to evaluate whether such movements contain sex-specific characteristics. Therefore, the purposes of this study were: (1) to quantify in detail the jaw movements and associated masticato...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345970760031301

    authors: Gerstner GE,Parekh VV

    更新日期:1997-03-01 00:00:00

  • Metabolism of gingival collagen in a rat.

    abstract::The remodeling of gingival tissue was measured by determining the incorporation of tritiated proline and the disappearance of tritium activity from proline and hydroxyproline for 18 days after administration of label. There was a rapid decrease in the tritium activity from gingiva which was paralleled by a decrease in...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345780570023101

    authors: Orlowski WA

    更新日期:1978-02-01 00:00:00

  • High-temperature X-ray diffraction measurement of sanidine thermal expansion.

    abstract::Dental porcelains that are designed to be fused to PFM (porcelain-fused-to-metal) alloys are formulated by their manufacturers to be closely matched in thermal expansion to these alloys. The high thermal expansion of the mineral leucite has been exploited to regulate porcelain expansion. Leucite, however, has been obs...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345000790081101

    authors: Mackert JR Jr,Twiggs SW,Williams AL

    更新日期:2000-08-01 00:00:00

  • Impact of Carbamide Peroxide Whitening Agent on Dentinal Collagen.

    abstract::Carbamide peroxide (CP) is widely used as a tooth-whitening agent in self-administered tooth-bleaching products. In this study, the effects of 5% and 10% CP on dentinal collagen structure and chemical properties were evaluated in vitro. Thirty-five intact teeth were exposed to 2 whitening protocols (2 or 4 h daily) wi...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034518822826

    authors: Redha O,Strange A,Maeva A,Sambrook R,Mordan N,McDonald A,Bozec L

    更新日期:2019-04-01 00:00:00

  • Crevice corrosion products of dental amalgam.

    abstract::The objective of this study was to determine the in vitro corrosion products that resulted from crevice corrosion of low- and high-copper dental amalgams. Specimens were potentiostatically polarized in a chloride-containing electrolyte while set against a PTFE surface to form a crevice. After 16 h, corrosion products ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345910700071301

    authors: Sutow EJ,Jones DW,Hall GC,Owen CG

    更新日期:1991-07-01 00:00:00

  • Genes and related proteins involved in amelogenesis imperfecta.

    abstract::Dental enamel formation is a remarkable example of a biomineralization process. The exact mechanisms involved in this process remain partly obscure. Some of the genes encoding specific enamel proteins have been indicated as candidate genes for amelogenesis imperfecta. Mutational analyses within studied families have s...

    journal_title:Journal of dental research

    pub_type: 杂志文章,评审

    doi:10.1177/154405910508401206

    authors: Stephanopoulos G,Garefalaki ME,Lyroudia K

    更新日期:2005-12-01 00:00:00

  • The resistance and adaptation of selected oral bacteria to mercury and its impact on their growth.

    abstract::Selected strains of oral Streptococcus and Actinomyces have been tested for their ability to grow in the presence of mercury. Strains were tested for growth on a semi-defined medium with low mercury-binding characteristics. Sensitivities were initially measured on agar plates, and subsequently, selected strains were g...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345930720091201

    authors: Lyttle HA,Bowden GH

    更新日期:1993-09-01 00:00:00

  • Chemical and molecular weight analyses of prosthodontic soft polymers.

    abstract::A number of studies have been made investigating the properties of dental prosthodontic soft polymer materials. In such materials, which are used as short-term denture soft liners, the polymer component is complexed with one or more plasticizers. This lowers the glass transition temperature, Tg, of the polymer by allo...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345910700050201

    authors: Jones DW,Hall GC,Sutow EJ,Langman MF,Robertson KN

    更新日期:1991-05-01 00:00:00

  • Global Economic Impact of Dental Diseases.

    abstract::Reporting the economic burden of oral diseases is important to evaluate the societal relevance of preventing and addressing oral diseases. In addition to treatment costs, there are indirect costs to consider, mainly in terms of productivity losses due to absenteeism from work. The purpose of the present study was to e...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034515602879

    authors: Listl S,Galloway J,Mossey PA,Marcenes W

    更新日期:2015-10-01 00:00:00

  • PAR-1 and PAR-2 Expression Is Enhanced in Inflamed Odontoblast Cells.

    abstract::Protease-activated receptors (PARs) are G protein-coupled receptors, which are activated by proteolytical cleavage of the amino-terminus and act as sensors for extracellular proteases. We hypothesized that PAR-1 and PAR-2 can be modulated by inflammatory stimulus in human dental pulp cells. PAR-1 and PAR-2 gene expres...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034517719415

    authors: Alvarez MMP,Moura GE,Machado MFM,Viana GM,de Souza Costa CA,Tjäderhane L,Nader HB,Tersariol ILS,Nascimento FD

    更新日期:2017-12-01 00:00:00

  • Axon reflex vasodilatation in cat dental pulp elicited by noxious stimulation of the gingiva.

    abstract::Antidromic stimulation of sensory nerves has been shown to increase blood flow in the tissue they innervate. This study was designed to determine if antidromic vasomotor responses occur in feline dental pulp and if they are mediated by branched axons supplying both tooth pulp and gingiva. Dynamic changes in pulpal blo...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345940730120201

    authors: Sasano T,Kuriwada S,Shoji N,Sanjo D,Izumi H,Karita K

    更新日期:1994-12-01 00:00:00

  • Fluoride Mode of Action: Once There Was an Observant Dentist . . .

    abstract::The discovery and implementation of fluoride in the prevention of dental caries is often praised as one of the most important achievements in health care. In the early 20th century, it took 30 y to identify fluoride as the cause of enamel mottling but also of reduced caries prevalence in a population drinking water co...

    journal_title:Journal of dental research

    pub_type: 历史文章,杂志文章

    doi:10.1177/0022034519831604

    authors: Ten Cate JM,Buzalaf MAR

    更新日期:2019-07-01 00:00:00

  • Cohort effects in the prevalence of caries in child populations in Tanzania.

    abstract::In 1984, a four-year mixed-longitudinal study of oral health was begun in Morogoro Town and Morogoro District, Tanzania. Its main goal was to detect a possible upward trend in prevalence of caries in child cohorts in this developing country. The sample consisted of 722 seven- to nine-year-olds in 1984, 833 seven- to 1...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345890680121101

    authors: Frencken JE,Van 't Hof MA,Truin GJ,Lembariti BS,König KG

    更新日期:1989-12-01 00:00:00

  • Magnification--a new look at a long-known optical property of dentin.

    abstract::Light propagation in human dentin exhibits a strong directional dependence featuring the long-known optical magnification property. We hypothesized that this anisotropic effect is caused by multiple scattering at the dentin tubules, and not by fiberoptic effects, as had been previously assumed. We performed measuremen...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910608501017

    authors: Kienle A,Michels R,Hibst R

    更新日期:2006-10-01 00:00:00

  • Procedures for establishing efficacy of antimicrobial agents for chemotherapeutic caries prevention.

    abstract::Chemotherapeutics are presently considered for use in caries-preventive programs. The laboratory and in vivo testing of these agents, to some extent, parallels the methodology developed for the evaluation of fluoride products. However, fluoride is primarily effective by interfering with the de- and remineralization ba...

    journal_title:Journal of dental research

    pub_type: 杂志文章,评审

    doi:10.1177/00220345940730031601

    authors: ten Cate JM,Marsh PD

    更新日期:1994-03-01 00:00:00

  • Oral fluoride measurements for estimation of the anti-caries efficacy of fluoride treatments.

    abstract::The aims of this work were (a) to assess the oral bioavailability of fluoride delivered from dentifrices and (b) to test for a possible link between the results and clinical data obtained with the same dentifrices. Oral fluoride concentrations were measured in samples of saliva and plaque taken from seven subjects, af...

    journal_title:Journal of dental research

    pub_type: 临床试验,杂志文章,评审

    doi:10.1177/002203459207100S09

    authors: Duckworth RM,Morgan SN,Gilbert RJ

    更新日期:1992-04-01 00:00:00

  • Oxygen inhibition in dental resins.

    abstract::Oxygen inhibits free radical polymerization and yields polymers with uncured surfaces. This is a concern when thin layers of resin are being polymerized, or in circumstances where conventional means of eliminating inhibition are inappropriate. In this study, we tested the hypothesis that viscosity, filler content, and...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910508400808

    authors: Gauthier MA,Stangel I,Ellis TH,Zhu XX

    更新日期:2005-08-01 00:00:00

  • Glycogen synthetic abilities of Actinomyces viscosus and Actinomyces naeslundii freshly isolated from dental plaque over root surface caries lesions and non-carious sites.

    abstract::Relative glycogen synthetic abilities of resting cells of fresh clinical isolates of Actinomyces viscosus and Actinomyces naeslundii originating from dental plaque samples over root surface caries lesions and non-carious sites were studied under anaerobic conditions at a constant pH of 7.0, with U-(14C)-glucose used a...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345860650060701

    authors: Komiyama K,Khandelwal RL,Duncan DE

    更新日期:1986-06-01 00:00:00

  • Thio-urethanes improve properties of dual-cured composite cements.

    abstract::This study aims at modifying dual-cure composite cements by adding thio-urethane oligomers to improve mechanical properties, especially fracture toughness, and reduce polymerization stress. Thiol-functionalized oligomers were synthesized by combining 1,3-bis(1-isocyanato-1-methylethyl)benzene with trimethylol-tris-3-m...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034514551768

    authors: Bacchi A,Dobson A,Ferracane JL,Consani R,Pfeifer CS

    更新日期:2014-12-01 00:00:00

  • Water aging reverses residual stresses in hydrophilic dental composites.

    abstract::Dental composites develop residual stresses during polymerization due to shrinkage. These stresses may change with time because of relaxation and water sorption in the oral environment. This phenomenon is likely dependent on the composition of the materials, specifically their hydrophilic characteristics, and could re...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034513513905

    authors: Park JW,Ferracane JL

    更新日期:2014-02-01 00:00:00

  • Antimalarial drugs and reduced incidence of dental plaque.

    abstract::Known antimalarial compunds from several chemical classes were tested for their ability to inhibit in vitro growth of microorganisms causing dental plaque and to prevent the development of plaque in a hamster model. Approximately a third of the compounds tested inhibited in vitro growth; however, none prevented develo...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345750540030901

    authors: Kinnamon KE,Eckermann EH,Tempel TR,Smith JH,Wolf CR

    更新日期:1975-05-01 00:00:00

  • Rate modulation of jaw-elevator motor units as revealed from the low-frequency power spectrum of the surface electromyogram in myogenous CMD patients.

    abstract::The firing pattern of the motor units (MUs) in jaw-elevator muscles was studied within a wide range of isometric contraction levels by means of changes in the frequency and broadness of the primary peak in the low-frequency (5-40 Hz) power spectral density function of the surface EMG. EMG was recorded from both masset...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345940730051501

    authors: van der Glas HW,Lobbezoo F,Buchner R,van der Bilt A,Bosman F

    更新日期:1994-05-01 00:00:00

  • Hyperocclusion up-regulates CCL3 expression in CCL2- and CCR2-deficient mice.

    abstract:UNLABELLED:Excessive mechanical stress (MS) during hyperocclusion is known to result in disappearance of the alveolar hard line, enlargement of the periodontal ligament (PDL) space, and destruction of alveolar bone, leading to occlusal traumatism. We have recently reported that MS induces predominantly C-C chemokine li...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034512467803

    authors: Tsutsumi T,Kajiya H,Goto KT,Takahashi Y,Okabe K

    更新日期:2013-01-01 00:00:00