Abstract:
:Extracellular microcapsules have been demonstrated on cells of most serotypes of Streptococcus mutans by electron microscopy, using bacterial strains of the various serotypes and peroxidase labeled or unlabeled immune serum. A correlation was noted between the amount of capsular substance on the strains of S mutans examined and degree of antigenicity as expressed by the indirect fluorescent antibody (FA) title. A serotype d strain was shown to lose both antigenicity as determined by the FA reaction and capsular material as seen by electron microscopy with repeated in vitro passage. When 10% unheated rabbit serum was added to the medium, antigenicity and capsular material were restored.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Grenier EM,Gray RH,Loesche WJ,Eveland WCdoi
10.1177/00220345770560021101subject
Has Abstractpub_date
1977-02-01 00:00:00pages
166-76issue
2eissn
0022-0345issn
1544-0591journal_volume
56pub_type
杂志文章abstract::The cacao bean husk has been shown to possess two types of cariostatic substances, one showing anti-glucosyltransferase (GTF) activity and the other antibacterial activity, and to inhibit experimental dental caries in rats infected with mutans streptococci. In the present study, chromatographic purification revealed h...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345010800111001
更新日期:2001-11-01 00:00:00
abstract::The tooth resistance measuring instrument was compared to the traditional method of the explorer examination for the detection of occlusal carious lesions. The findings of the instrument were more sensitive as compared to the traditional method when verified by a histological examination. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345780570020801
更新日期:1978-02-01 00:00:00
abstract::Although a secular decline is being seen in coronal caries in children in industrialized countries, there appears to be a relatively high prevalence of root caries, with chronologically older adults exhibiting the highest prevalences. This paper reviews the descriptive and analytical epidemiology of root caries as fou...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345900690051901
更新日期:1990-05-01 00:00:00
abstract::A full understanding of the key regulators controlling periodontal development and homeostasis is necessary for the design of improved periodontal regenerative therapies. Small leucine-rich proteoglycans (SLRPs) are extracellular matrix molecules suggested to regulate collagen organization and cell signaling. Mice wit...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514541126
更新日期:2014-08-01 00:00:00
abstract::Dental pulp regeneration therapy for the pulpless tooth has attracted recent attention, and clinical trial studies are underway with the tissue engineering approach. However, there remain many concerns, including the extended period for regenerating the dental pulp. In addition, the use of scaffolds increases the risk...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034518772260
更新日期:2018-09-01 00:00:00
abstract::Although certain bacterial species appear to be risk factors for pain due to odontogenic infections, comparatively little is known about the potential mechanisms mediating this effect. In this study, we tested the hypothesis that trigeminal nociceptive neurons express the TLR4 or CD14 receptors, thus enabling sensory ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500108
更新日期:2006-01-01 00:00:00
abstract::Sintered samples of modifying porcelains of various colors and manufacturers were analyzed using reflectance spectrophotometry. Color designations are reported according to practices of the Commission Internationale de l'Eclairage (International Commission for Illumination), and color names were assigned based on a me...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345820610030801
更新日期:1982-03-01 00:00:00
abstract::Resin-bonded bridges may replace missing teeth and act as splints in periodontal treatment. The objective of this study was to investigate the etch pattern after electrolytic etching of selected Co-Cr alloys in hydrochloric acid and to assess the changes in alloy composition after different etching times. The alloys i...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660091301
更新日期:1987-09-01 00:00:00
abstract::Samples of a base mental alloy were cast and welded together using a conventional welding procedure. The joints were loaded and placed either in a corrosive environment or in air for varying time periods. The tensile and shear strength of the joints was unaffected by the corrosive environment, and the joints, despite ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600021101
更新日期:1981-02-01 00:00:00
abstract::A quantitative microprobe analysis was conducted on three commercial amalgams to determine the nature of the phases present. The presence of tin in the Ag-Hg phase (gamma1) was confirmed and Cu-3Sn was found in the original alloy particles. In the dispersant amalgam studied, little Sn-Hg phase (gamma-2) was found and ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::Inflammatory conditions as they occur during periodontal disease often result in decreased alveolar bone levels and a loss of connective tissue homeostasis. Here we have focused on the effect of microRNA-138 (miR-138) as a potential regulator of periodontal stem cells as they affect homeostasis during inflammatory con...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515613043
更新日期:2016-02-01 00:00:00
abstract::The expired air of a group of 48 persons, 40 with and eight without dental amalgam restorations, was analyzed for its mercury content before and after chewing. Expired air samples were collected in polyethylene bags, and a known quantity of each was pumped into the mercury detector for measurement. The results showed ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600090601
更新日期:1981-09-01 00:00:00
abstract::The oral cavity contains a rich consortium of exopolysaccharide-producing microbes. These extracellular polysaccharides comprise a major component of the oral biofilm. Together with extracellular proteins, DNA, and lipids, they form the biofilm matrix, which contributes to bacterial colonization, biofilm formation and...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034519845001
更新日期:2019-07-01 00:00:00
abstract::The importance of assessing the impact of treatments for chronic conditions on an individual's quality of life has been well-established. In this randomized clinical trial, oral-health-related quality of life, measured with the Oral Health Impact Profile (OHIP), was compared between two groups of edentulous patients. ...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/00220345000790090401
更新日期:2000-09-01 00:00:00
abstract::In 1986, the first nationwide epidemiological survey of adult oral health and attitudes to oral health care was carried out in The Netherlands. One of the aims of this study was to evaluate the prevalence and the quality (in terms of need for replacement) of amalgam and composite restorations in the Dutch adult popula...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345900690060901
更新日期:1990-06-01 00:00:00
abstract::The fatigue crack growth resistance of dentin was characterized as a function of depth from the dentino-enamel junction. Compact tension (CT) specimens were prepared from the crowns of third molars in the deep, middle, and peripheral dentin. The microstructure was quantified in terms of the average tubule dimensions a...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034511408429
更新日期:2011-08-01 00:00:00
abstract::Extracellular matrix (ECM) mineralization is regulated by mineral ion availability, proteins, and other molecular determinants. To investigate protein regulation of mineralization in tooth dentin and cementum, and in alveolar bone, we expressed matrix Gla protein (MGP) ectopically in bones and teeth in mice, using an ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700907
更新日期:2008-09-01 00:00:00
abstract::In the past decade, medical genetic research has generated multiple discoveries, many of which were obtained via genome-wide association studies (GWASs). A major GWAS finding is that the majority of risk variants for complex traits map to noncoding regions. This has resulted in a paradigm shift in terms of the interpr...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034517720403
更新日期:2017-10-01 00:00:00
abstract::The distribution of immunoglobulin-containing cells in human tonsils, salivary glands, and inflamed gingiva is described. The cellular localization of J chain indicates that this peptide is a basic gene product of B cells that is expressed only in the early phase of clonal differentiation. Gland-associated immunocytes...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/002203457605500301011
更新日期:1976-04-01 00:00:00
abstract::Acculturation is a complex phenomenon that can serve as a proxy for cultural norms and behaviors affecting care-seeking, prevention behaviors, and, ultimately, health outcomes. The purpose of this study was to assess the effect of acculturation on the oral health of Haitian immigrants in New York City. We hypothesized...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910408300219
更新日期:2004-02-01 00:00:00
abstract::It is claimed that dental fluorosis in both deciduous and permanent teeth is increasing in fluoridated and non-fluoridated communities. What is unclear is whether fluoride-induced enamel opacities in the deciduous dentition are associated with the subsequent appearance of enamel defects in the permanent dentition. The...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750040301
更新日期:1996-04-01 00:00:00
abstract::Matrix metalloproteinase (MMP) inhibition has been shown to reduce adhesive bond degradation when applied as a pre-conditioner, adding to clinical steps in the placement of adhesives, but their incorporation within dental adhesives has not been fully explored. This study examined the effect of including 2 MMP inhibito...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034512446339
更新日期:2012-06-01 00:00:00
abstract::The flexure moduli of elasticity of solid and multi-stranded orthodontic wires were determined. Results for the solid wires approximated their tensile values, but the differences were statistically significant for the stainless steel, chromium-cobalt-nickel, and nickel-titanium alloys. The flexure moduli of the multi-...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620072201
更新日期:1983-07-01 00:00:00
abstract::Although systemic bone loss accompanying estrogen deficiency has been proposed as a risk factor for periodontal disease in post-menopausal women, the mechanisms involved remain unclear. The objective of this study was to elucidate the potential bone-sparing effect of estrogen (17beta-estradiol, E(2)) via modulation of...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700214
更新日期:2008-02-01 00:00:00
abstract::Symphyseal secondary cartilage is important for mandibular development, but the molecular mechanisms underlying its formation remain largely unknown. Here we asked whether Indian hedgehog (Ihh) regulates symphyseal cartilage development and growth. By embryonic days 16.5 to 18.5, Sox9-expressing chondrocytes formed wi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510397836
更新日期:2011-05-01 00:00:00
abstract::Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516645796
更新日期:2016-08-01 00:00:00
abstract::Candida colonization of the oral cavity increases in the elderly. A major predisposing condition is denture use, which also increases in the elderly. To test whether the increase in colonization is age-related in a fashion independent of denture use, we analyzed the frequency (incidence) of carriage, the intensity of ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345990780040601
更新日期:1999-04-01 00:00:00
abstract::Spontaneously occurring bacteriophage-resistant mutants of Actinomyces viscosus were isolated. The mutants exhibited altered coaggregation patterns with streptococci. From analysis of the data, it appears that a cell surface structure on A. viscosus may function both as a phage receptor and as a binding site for co-ag...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620111801
更新日期:1983-11-01 00:00:00
abstract::Periodontitis is a chronic infectious disease driven by dysbiosis, an imbalance between commensal bacteria and the host organism. Periodontitis is a leading cause of tooth loss in adults and occurs in about 50% of the US population. In addition to the clinical challenges associated with treating periodontitis, the pro...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515611876
更新日期:2016-02-01 00:00:00
abstract::Overgrowth of oral yeast is a common problem among the elderly. Probiotic bacteria are known to inhibit the growth of pathogenic microbes. We tested the hypothesis that cheese containing probiotic bacteria can reduce the prevalence of oral Candida. During this 16-week, randomized, double-blind, placebo-controlled stud...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/154405910708600204
更新日期:2007-02-01 00:00:00