Probiotics reduce the prevalence of oral candida in the elderly--a randomized controlled trial.

Abstract:

:Overgrowth of oral yeast is a common problem among the elderly. Probiotic bacteria are known to inhibit the growth of pathogenic microbes. We tested the hypothesis that cheese containing probiotic bacteria can reduce the prevalence of oral Candida. During this 16-week, randomized, double-blind, placebo-controlled study, 276 elderly people consumed daily 50 g of either probiotic (n = 136) or control cheese (n = 140). The primary outcome measure was the prevalence of a high salivary yeast count (>or= 10(4) cfu/mL) analyzed by the Dentocult method. The prevalence decreased in the probiotic group from 30% to 21% (32% reduction), and increased in the control group from 28% to 34%. Probiotic intervention reduced the risk of high yeast counts by 75% (OR = 0.25, 95%CI 0.10-0.65, p = 0.004), and the risk of hyposalivation by 56% (OR = 0.44, 95%CI 0.19-1.01, p = 0.05). Thus, probiotic bacteria can be effective in controlling oral Candida and hyposalivation in the elderly.

journal_name

J Dent Res

authors

Hatakka K,Ahola AJ,Yli-Knuuttila H,Richardson M,Poussa T,Meurman JH,Korpela R

doi

10.1177/154405910708600204

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

125-30

issue

2

eissn

0022-0345

issn

1544-0591

pii

86/2/125

journal_volume

86

pub_type

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