Abstract：
:Two independent cross-over studies investigated the possibility of enhanced early enamel lesion remineralization with the use of chewing gum. The first study involved a sorbitol-containing chewing gum, and the second, which had an identical protocol, tested a sucrose-containing chewing gum. In each study, 12 volunteers wore in situ appliances on which were mounted enamel sections containing artificial caries lesions. Subjects brushed twice daily for two min with a 1100-ppm-F (NaF) dentifrice (control and test) and in the test phase chewed five sticks of gum per day for 20 min after meals and snacks. Microradiographs of the enamel lesions were made at baseline and at the end of the seven-week experimental period. In the sugar-free gum study, the weighted mean total mineral loss (delta z) difference [(wk7-wk0) x (-1)] was 788 vol.% min. x micron for the gum, corresponding to remineralization of 18.2%, vs. the control value of 526 vol.% min. x micron, 12.1% remineralization (p = 0.07). There were no significant differences for the surface-zone (p = 0.20) and lesion-body (p = 0.28) values. In the sucrose-containing gum study, the delta z difference was 743 vol.% min. x micron for the gum, corresponding to a remineralization of 18.3%, vs. the control value of 438 vol.% min. x micron, 10.8% remineralization (p = 0.08). The surface-zone values were not significantly different (p = 0.55). For the lesion body, however, the sucrose-containing gum value of 6.11 vol.% min. was significantly different (p = 0.01) from that of the control (2.81 vol.% min.).
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Creanor SL,Strang R,Gilmour WH,Foye RH,Brown J,Geddes DA,Hall AFdoi
10.1177/00220345920710120801keywords:
subject
Has Abstractpub_date
1992-12-01 00:00:00pages
1895-900issue
12eissn
0022-0345issn
1544-0591journal_volume
71pub_type
临床试验,杂志文章abstract：:Previous studies of tooth size in twins and their families have suggested a high degree of genetic control, although there have been difficulties separating the various genetic and environmental effects. A genetic analysis of variation in crown size of the permanent incisors of South Australian twins was carried out, ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345950740071101
更新日期：1995-07-01 00:00:00
abstract：:The Triggering Receptor Expressed on Myeloid cells 1 (TREM-1) is a cell-surface receptor of the immunoglobulin superfamily, involved in the propagation of the inflammatory response to bacterial challenge. Soluble (s)TREM-1 is released from the cell surface during the course of infection and is a useful inflammatory bi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034512470691
更新日期：2013-02-01 00:00:00
abstract：:A double-blind randomized clinical trial was performed in 6- to 7-yr-old schoolchildren to evaluate, in a 30-mo period, whether the caries increment on the distal surface of the second primary molars adjacent to permanent first molars sealed with fluoride release compounds would be lower with respect to those adjacent...
journal_title：Journal of dental research
pub_type： 杂志文章,随机对照试验
doi：10.1177/0022034514535808
更新日期：2014-07-01 00:00:00
abstract：:Polynomial and catenary equations were fit by least square error methods to the dentitions of seven children with "normal" occlusion. Mean and mean square error were then used to analyze accuracy of curve fits and asymmetries of arches. A lack of congruency for the "lines of occlusion" common to the maxilla and mandib...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345750540060501
更新日期：1975-11-01 00:00:00
abstract：:The human mandibular condyle has a parasagittal plate-like trabecular structure. We tested the hypothesis that this structure reflects the mechanical loading of the condyle. We developed a finite element model of the condyle to analyze the strains occurring during static compressive loading. The principal strains in t...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910208101010
更新日期：2002-10-01 00:00:00
abstract：:During orofacial tissue development, the anterior and posterior regions of the Meckel's cartilage undergo mineralization, while the middle region undergoes degeneration. Despite the interesting and particular phenomena, the mechanisms that regulate the different fates of Meckel's cartilage, including the effects of bi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520960118
更新日期：2021-02-01 00:00:00
abstract：:The purpose of this study was to determine the surface roughness of enamel-to-enamel contact areas in order to provide a standard for comparison with surface characteristics of commercially available composite restorative materials. In addition, the inherent surface roughness of resin composites was evaluated profilom...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345910700091301
更新日期：1991-09-01 00:00:00
abstract：:Growth factors such as epidermal growth factor (EGF) and transforming growth factor-alpha (TGF-alpha) play an important role in cell proliferation during embryogenesis. The purposes of the study were to characterize the expression patterns of EGF and TGF-alpha and their receptor, EGF receptor (EGF-R), and to analyze r...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345960750080301
更新日期：1996-08-01 00:00:00
abstract：:In this study, the effects of eugenol on human polymorphonuclear (PMN) cell migration and chemiluminescence were examined in vitro. Utilizing zymosan-activated serum or crude Bacteroides sonicate fractions as chemotractants, we found that eugenol inhibits PMN migration at 6.6 X 10(-2) to 6.6 X 10(-5) mol/L (P less tha...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345870660031401
更新日期：1987-03-01 00:00:00
abstract：:Candida colonization of the oral cavity increases in the elderly. A major predisposing condition is denture use, which also increases in the elderly. To test whether the increase in colonization is age-related in a fashion independent of denture use, we analyzed the frequency (incidence) of carriage, the intensity of ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345990780040601
更新日期：1999-04-01 00:00:00
abstract：:Deciduous teeth were collected from children who received professional prophylaxis with an acidulated phosphate-fluoride (APF) or placebo paste and were analyzed to determine fluoride uptake. Enamel fluoride level was increased by the APF paste approximately 300 ppm at a depth of 2.5 micrometers during the first month...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345760550064901
更新日期：1976-11-01 00:00:00
abstract：:There is a large variability between and among individuals in the physiology of mastication, but it is not known whether this produces a similar variability in the particle sizes of food boluses at the end of the chewing process. Food boluses obtained just before swallowing were analyzed in ten subjects (aged 36.7 +/-...
journal_title：Journal of dental research
pub_type： 临床试验,杂志文章
doi：10.1177/154405910408300713
更新日期：2004-07-01 00:00:00
abstract：:Lingual amylase and lingual lipase, two digestive enzymes that are secreted from lingual serous glands (von Ebner's), were simultaneously purified from rat lingual serous glands with hydrophobic chromatography used as the final step. This method, previously developed for the purification of lingual lipase, includes ho...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345890680020801
更新日期：1989-02-01 00:00:00
abstract：:Urinary catecholamines have been used to measure emotionally stressful states which may affect the development of dental caries. This study investigates the hypothesis that children with and without dental caries do not differ significantly in the mean values of urinary catecholamines such as epinephrine, norepinephri...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345950740100801
更新日期：1995-10-01 00:00:00
abstract：:Oral bacteria, including Streptococcus mutans and Streptococcus salivarius, contribute to tooth decay and plaque formation; therefore, it is essential to develop strategies to prevent dental caries and plaque formation. We recently showed that organo-selenium compounds covalently attached to different biomaterials inh...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513482141
更新日期：2013-05-01 00:00:00
abstract：:The synthesis of many polycarboxylic acids is reported. An account is given of their stability in aqueous solution and the properties of cements formed by their reaction with ion-leachable glasses. A copolymer of acrylic and itaconic acids was found to combine several favorable characteristics. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345800590060801
更新日期：1980-06-01 00:00:00
abstract：:The effect of low-level laser treatment on maxillary arch dimensions after palatal surgery was investigated in Beagle dogs at an age of 12 weeks. A total of 30 dogs was used, and they were assigned to either a control group (Group C, n = 6) or one of two experimental groups (Group L, n = 12; and group LL, n = 12). Aft...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345910700111501
更新日期：1991-11-01 00:00:00
abstract：:The effects of different doses of p-tyramine injected i.v. and i.p. on salivary flow rates and proteins secreted by the submandibular glands of rats were studied with and without various types of autonomic blockers and two enzyme inhibitors. The salivary flow rates and the amounts of protein secreted progressively inc...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720051101
更新日期：1993-05-01 00:00:00
abstract：:Much research has been devoted to the study of etched enamel, since it is critical to bonding. Currently, there are no precise data regarding the etched-enamel specific surface area. The aim of this study was to characterize, by two different methods, the surface of human dental enamel in vitro after being etched. It ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910808700607
更新日期：2008-06-01 00:00:00
abstract：:Experimental marginal leakage of high- and low-Cu amalgam restorations placed in acrylic teeth, where the cavities were untreated or painted with denatured collagen and/or a CaP slurry, was assessed after specimens were stored in a 1% NaCl solution for ten days and for one yr. All specimens stored for ten days showed ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630081801
更新日期：1984-08-01 00:00:00
abstract：:Matrix metalloproteinase (MMP) inhibition has been shown to reduce adhesive bond degradation when applied as a pre-conditioner, adding to clinical steps in the placement of adhesives, but their incorporation within dental adhesives has not been fully explored. This study examined the effect of including 2 MMP inhibito...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034512446339
更新日期：2012-06-01 00:00:00
abstract：:Mixed or parotid saliva from caries-active individuals consistently supported better growth of Streptococcus mutans (type c) than that from caries-free individuals. Electrophoretic studies revealed that certain proteins in caries-active salivas were susceptible to microbial attack, but similar proteins in caries-free ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345790580101501
更新日期：1979-10-01 00:00:00
abstract：:Wear striations experimentally produced on initially unworn teeth were examined at high magnification using a scanning electron microscope. Certain characteristics of individual wear striations on these teeth indicate the direction of motion that produced them. Other striations on worn teeth of American Indians and th...
journal_title：Journal of dental research
pub_type： 历史文章,杂志文章
doi：10.1177/00220345790580011401
更新日期：1979-01-01 00:00:00
abstract：:Ammoniacal silver stain showed that there was a decrease in nucleohistones in zinc-deficient rat buccal hyperplastic epithelium as compared to control. Autoradiographic study showed that there was decreased incorporation of 3H-arginine and 3H-lysine in the hyperplastic epithelium. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560122501
更新日期：1977-12-01 00:00:00
abstract：:Defects in the enamelin gene (ENAM) cause amelogenesis imperfecta (AI). Our objective was to identify the genetic etiology of enamel hypoplasia in a Caucasian proband. Our hypothesis was that ENAM was defective. The proband and his father have an AG insertion (g.13185_13186insAG; p.422FsX448) in ENAM previously identi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510365662
更新日期：2010-07-01 00:00:00
abstract：:Periodontitis is a complex, multifactorial chronic disease involving continuous interactions among bacteria, host immune/inflammatory responses, and modifying genetic and environmental factors. More than any other cytokine family, the interleukin (IL)-1 family includes key signaling molecules that trigger and perpetua...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520945209
更新日期：2020-12-01 00:00:00
abstract：:The aim of this study was to investigate the involvement of autoimmune reactions to native and post-translationally modified extracellular matrix components in the pathogenesis of periodontitis. Sera from individuals with aggressive periodontitis (AgP, n = 25), chronic periodontitis (CP, n = 14), and gingivitis (G, n ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510381903
更新日期：2010-12-01 00:00:00
abstract：:The benefits of early orthodontic treatment are continuously discussed, but studies are few. We examined whether definite need for orthodontic treatment could be eliminated in public health care by systematically focusing on early intervention. One age cohort living in a rural Finnish municipality (N = 85) was regular...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910808700604
更新日期：2008-06-01 00:00:00
abstract：:Dental porcelains that are designed to be fused to PFM (porcelain-fused-to-metal) alloys are formulated by their manufacturers to be closely matched in thermal expansion to these alloys. The high thermal expansion of the mineral leucite has been exploited to regulate porcelain expansion. Leucite, however, has been obs...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345000790081101
更新日期：2000-08-01 00:00:00
abstract：:Although it is known that diabetes impairs oral wound healing, relatively little is known about the cellular parameters affected, particularly in connective tissue. This study investigated the hypothesis that diabetes impairs connective tissue formation in healing gingiva, and that impaired healing is associated with ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510362960
更新日期：2010-06-01 00:00:00
