Altered enamelin phosphorylation site causes amelogenesis imperfecta.

abstract：:Fibroblast growth factor receptor 2 (FGFR2) in craniofacial bones mediates osteoprogenitor proliferation, differentiation, and apoptosis. The distortion of proper craniofacial bone growth may cause class II and class III skeletal malocclusion and result in compromised function and aesthetics. Here, we investigated the...

journal_title：Journal of dental research

authors： Jiang Q,Mei L,Zou Y,Ding Q,Cannon RD,Chen H,Li H

更新日期：2019-11-01 00:00:00

abstract：:The Global Burden of Disease (GBD) 2010 Study produced comparable estimates of the burden of 291 diseases and injuries in 1990, 2005, and 2010. This article reports on the global burden of untreated caries, severe periodontitis, and severe tooth loss in 2010 and compares those figures with new estimates for 1990. We u...

journal_title：Journal of dental research

authors： Marcenes W,Kassebaum NJ,Bernabé E,Flaxman A,Naghavi M,Lopez A,Murray CJ

更新日期：2013-07-01 00:00:00

abstract：:In the absence of active pulmonary disease, mycobacterial infection frequently causes arthritis and can be considered to initiate autoimmune diseases such as rheumatoid arthritis. Temporomandibular disorder (TMD) is a disease in which pain and impaired mandibular movement appear to arise directly from degenerative or ...

journal_title：Journal of dental research

authors： Adachi N,Matsumoto S,Tokuhisa M,Kobayashi K,Yamada T

更新日期：2000-10-01 00:00:00

abstract：:Class II major histocompatilibity complex (MHC)-expressing cells are usually distributed in dental pulp, and it was postulated that the colony-stimulating factor (CSF) derived from dental pulp fibroblasts contributes to the migration of class II MHC-expressing cells into pulp tissue. This study aimed to investigate th...

journal_title：Journal of dental research

authors： Sawa Y,Horie Y,Yamaoka Y,Ebata N,Kim T,Yoshida S

更新日期：2003-02-01 00:00:00

abstract：:Matrix metalloproteinase (MMP) inhibition has been shown to reduce adhesive bond degradation when applied as a pre-conditioner, adding to clinical steps in the placement of adhesives, but their incorporation within dental adhesives has not been fully explored. This study examined the effect of including 2 MMP inhibito...

journal_title：Journal of dental research

authors： Almahdy A,Koller G,Sauro S,Bartsch JW,Sherriff M,Watson TF,Banerjee A

更新日期：2012-06-01 00:00:00

abstract：:Levels of mutans streptococci in plaque samples from margins of Class II amalgam (Dispersalloy), composite (P-10), and glass-ionomer (Ketac Silver) restorations were compared. Fifty-one children, each having one of the restorations in a permanent first molar, were part of an inter-individual comparison, giving 17 rest...

journal_title：Journal of dental research

authors： Svanberg M,Mjör IA,Orstavik D

更新日期：1990-03-01 00:00:00

abstract：:Growing interest in the treatment and prevention of Molar/Incisor Hypomineralization (MIH) warrants investigation into the protein composition of hypomineralized enamel. Hypothesizing abnormality akin to amelogenesis imperfecta, we profiled proteins in hypomineralized enamel from human permanent first molars using a b...

journal_title：Journal of dental research

authors： Mangum JE,Crombie FA,Kilpatrick N,Manton DJ,Hubbard MJ

更新日期：2010-10-01 00:00:00

abstract：:The aim of this meta-analysis was to examine the clinical effectiveness of miniscrew implants (MI) used for anchorage reinforcement compared with that of conventional orthodontic means, as well as to assess the success rates of MIs and the possible risk factors affecting their clinical effectiveness. Literature search...

journal_title：Journal of dental research

authors： Papadopoulos MA,Papageorgiou SN,Zogakis IP

更新日期：2011-08-01 00:00:00

abstract：:Deciduous teeth were collected from children who received professional prophylaxis with an acidulated phosphate-fluoride (APF) or placebo paste and were analyzed to determine fluoride uptake. Enamel fluoride level was increased by the APF paste approximately 300 ppm at a depth of 2.5 micrometers during the first month...

journal_title：Journal of dental research

authors： Mellberg JR,Nicholson CR,Ripa LW,Barenie J

更新日期：1976-11-01 00:00:00

abstract：:Interleukin (IL)-23 is an essential cytokine involved in expansion of the Th17 lineage, which is associated with many immune-related destructive tissue diseases. We hypothesized that the IL-23-induced Th17 pathway plays a role in periodontal pathology and examined the expression of cytokines, and related molecules, in...

journal_title：Journal of dental research

authors： Ohyama H,Kato-Kogoe N,Kuhara A,Nishimura F,Nakasho K,Yamanegi K,Yamada N,Hata M,Yamane J,Terada N

更新日期：2009-07-01 00:00:00

abstract：:TWIST1 plays a crucial role in dentinogenesis, and its activity depends on both a dimerization partner selection and phosphorylation. Other factors, like Id proteins, can affect the availability of dimerization partners for TWIST1, subsequently leading to diverse biological outcomes. The purpose of this study was to e...

journal_title：Journal of dental research

authors： Maciejewska I,Sakowicz-Burkiewicz M,Pawelczyk T

更新日期：2014-06-01 00:00:00

abstract：:Cell kinetics of rat molar periodontal ligament (PDL) during orthodontically-induced osteogenesis revealed: 1) primary growth fraction of 59%, 2) proliferating cells from throughout the PDL migrate toward the bone surface, 3) preosteoblasts, capable of forming osteoblasts without synthesizing DNA, are present in the P...

journal_title：Journal of dental research

authors： Roberts WE,Chase DC

更新日期：1981-02-01 00:00:00

abstract：:Nitric oxide (.NO) modulates the activity of the endocrine system in the behavioral response to stress. The purpose of this study was to investigate the effect of restraining the body of an animal on expression of neuronal nitric oxide synthase (nNOS) in the paraventricular nucleus (PVN) of the hypothalamus, and the i...

journal_title：Journal of dental research

authors： Hori N,Lee MC,Sasaguri K,Ishii H,Kamei M,Kimoto K,Toyoda M,Sato S

更新日期：2005-07-01 00:00:00

abstract：:Bone remodeling is a complex process regulated by several mediators. Recent work has revealed that cytokines and growth factors have significant effects on bone cell metabolism. However, little information is available concerning the production of cytokines during orthodontic tooth movement in human subjects, and ther...

journal_title：Journal of dental research

authors： Uematsu S,Mogi M,Deguchi T

更新日期：1996-01-01 00:00:00

abstract：:Dissolution of mercury from the Ag-Hg matrix phase of dental amalgam is distilled water and synthetic saliva, and the mercury evaporation from the solutions, were studied in vitro. The main objectives of the study were to evaluate the factors that affect the results of the mercury release tests, and to consider the po...

journal_title：Journal of dental research

authors： Marek M

更新日期：1990-05-01 00:00:00

abstract：:This study investigated irregularities in hinge movement in 113 subjects. These irregularities were analyzed by computer with an instantaneous three-dimensional "screw axis method." The variation in hinge movement was measured by the dispersion of the hinge axis instant centers. Dispersion of instant centers was great...

journal_title：Journal of dental research

authors： Lupkiewicz SM,Gibbs CH,Mahan PE,Lundeen HC,Ariet M,Sinkewiz SL

更新日期：1982-01-01 00:00:00

abstract：:Fluid transudation through simplified dentin adhesives can occur in bonded vital crown dentin, since these adhesives behave as permeable membranes after polymerization. The effect of adhesive permeability in endodontically treated teeth is unknown. This study examined the hypothesis that in vivo fluid movement through...

journal_title：Journal of dental research

authors： Chersoni S,Acquaviva GL,Prati C,Ferrari M,Grandini S,Pashley DH,Tay FR

更新日期：2005-03-01 00:00:00

abstract：:The importance of assessing the impact of treatments for chronic conditions on an individual's quality of life has been well-established. In this randomized clinical trial, oral-health-related quality of life, measured with the Oral Health Impact Profile (OHIP), was compared between two groups of edentulous patients. ...

journal_title：Journal of dental research

authors： Awad MA,Locker D,Korner-Bitensky N,Feine JS

更新日期：2000-09-01 00:00:00

abstract：:Recent studies have shown that the extent of hydrolysis by plaque of the trypsin substrate, N-benzoyl-DL-arginine-2-naphthylamide (BANA), correlates with the numbers and proportions of spirochetes in subgingival plaque samples, and appears to be an indicator of clinical disease. In this study, BANA hydrolysis by subgi...

journal_title：Journal of dental research

authors： Schmidt EF,Bretz WA,Hutchinson RA,Loesche WJ

更新日期：1988-12-01 00:00:00

abstract：:These studies defined the normal and hormonally altered development of activity for tyrosine hydroxylase (T-OH), the rate-limiting enzyme in catecholamine biosynthesis (Levitt et al., 1965), and choline acetyltransferase activity (CAT) in the male rat superior cervical ganglion (SCG). Additionally, salivary gland weig...

journal_title：Journal of dental research

authors： Melvin JE,Hamill RW

更新日期：1987-03-01 00:00:00

abstract：:Hereditary diseases affecting the skeleton are heterogeneous in etiology and severity. Though many of these conditions are individually rare, the total number of people affected is great. These disorders often include dental-oral-craniofacial (DOC) manifestations, but the combination of the rarity and lack of in-depth...

journal_title：Journal of dental research

authors： Foster BL,Ramnitz MS,Gafni RI,Burke AB,Boyce AM,Lee JS,Wright JT,Akintoye SO,Somerman MJ,Collins MT

更新日期：2014-07-01 00:00:00

abstract：:Oxygen inhibits polymerization of resin-based materials. We hypothesized that compromised bonding to bleached enamel can be reversed with sodium ascorbate, an anti-oxidant. Sandblasted human enamel specimens were treated with distilled water (control) and 10% carbamide peroxide gel with or without further treatment wi...

journal_title：Journal of dental research

authors： Lai SC,Tay FR,Cheung GS,Mak YF,Carvalho RM,Wei SH,Toledano M,Osorio R,Pashley DH

更新日期：2002-07-01 00:00:00

abstract：:The complexity of human oral functional movements has not been studied in detail quantitatively, and only recently have studies begun to evaluate whether such movements contain sex-specific characteristics. Therefore, the purposes of this study were: (1) to quantify in detail the jaw movements and associated masticato...

journal_title：Journal of dental research

authors： Gerstner GE,Parekh VV

更新日期：1997-03-01 00:00:00

abstract：:The main goal of peri-implantitis treatment is to control infection and arrest bone loss, which requires the removal of polymicrobial biofilms on the implant surface and the reduction of tissue invasion. Additionally, prognosis can be improved if reosseointegration occurs on previously contaminated implants. To evalua...

journal_title：Journal of dental research

authors： Qin W,Wang C,Jiang C,Sun J,Yu C,Jiao T

更新日期：2020-07-01 00:00:00

abstract：:The objectives of the study were to describe the oral health status and treatment needs of the 5- to 6-year-old and 12-year-old children in Southern China; to describe the patterns of oral health behaviors, knowledge, and attitudes among the 12-year-olds; and to assess the effects of socio-behavioral factors on the 12...

journal_title：Journal of dental research

authors： Wong MC,Lo EC,Schwarz E,Zhang HG

更新日期：2001-05-01 00:00:00

abstract：:An infrared spectroscopic study has been made of the development of crystallinity (hopeite) in dental zinc phosphate cements. Crystallization in the bulk of a cement is prevented only by the incorporation, in the liquid, of aluminum which forms complexes with phosphoric acid. The development of surface crystallinity i...

journal_title：Journal of dental research

authors： Crisp S,O'Neill IK,Prosser HJ,Stuart B,Wilson AD

更新日期：1978-02-01 00:00:00

abstract：:Short-chain carboxylic acids (e.g., lactic acid, propionic acid, butyric acid) are metabolic by-products of bacterial metabolism which can accumulate in the gingival crevice. It is of no small consequence, therefore, that 1- to 5-mM concentrations of these acids exhibit significant biological activity, including the a...

journal_title：Journal of dental research

authors： Niederman R,Buyle-Bodin Y,Lu BY,Robinson P,Naleway C

更新日期：1997-01-01 00:00:00

abstract：:We have previously reported the clinical and radiographic findings of a trial in dogs of a new dental implant system after a functional period of eight months. The present report consists of the corresponding qualitative and quantitative histological data. The implant system was fabricated from Ti-6A1-4V and employed ...

journal_title：Journal of dental research

authors： Deporter DA,Watson PA,Pilliar RM,Howley TP,Winslow J

更新日期：1988-09-01 00:00:00

abstract：:In this study, we first investigated the expressions of Jagged1, Notch2, the receptor activator of nuclear factor-kappa B ligand (RANKL), and interleukin (IL)-6 in areas of root resorption during experimental tooth movement in rats in vivo. We then assessed the effects of compression force (CF) with or without GSI (an...

journal_title：Journal of dental research

authors： Kikuta J,Yamaguchi M,Shimizu M,Yoshino T,Kasai K

更新日期：2015-01-01 00:00:00

abstract：:The molecular mechanisms that maintain the equilibrium of odontoblast progenitor cells in dental pulp are unknown. Here we tested whether homeostasis in dental pulp is modulated by Twist-1, a nuclear protein that partners with Runx2 during osteoblast differentiation. Our analysis of Twist-1(+/-) mice revealed phenotyp...

journal_title：Journal of dental research

authors： Galler KM,Yasue A,Cavender AC,Bialek P,Karsenty G,D'Souza RN

更新日期：2007-10-01 00:00:00