The surface roughness of enamel-to-enamel contact areas compared with the intrinsic roughness of dental resin composites.

abstract：:The ability of adhesive resins to restore the physical properties of demineralized dentin has not been well-documented. The unfilled resins that are used for adhesion have relatively low moduli of elasticity and limited ability to increase dentin stiffness, although they may increase the ultimate tensile strength of d...

journal_title：Journal of dental research

authors： Sano H,Takatsu T,Ciucchi B,Russell CM,Pashley DH

更新日期：1995-04-01 00:00:00

abstract：:Histone deacetylases (HDACs) are important regulators of gene expression that are aberrantly regulated in several inflammatory and infectious diseases. HDAC inhibitors (HDACi) suppress inflammatory activation of various cell types through epigenetic and non-epigenetic mechanisms, and ameliorate pathology in a mouse mo...

journal_title：Journal of dental research

authors： Lagosz KB,Bysiek A,Macina JM,Bereta GP,Kantorowicz M,Lipska W,Sochalska M,Gawron K,Kaczmarzyk T,Chomyszyn-Gajewska M,Fossati G,Potempa J,Grabiec AM

更新日期：2020-01-01 00:00:00

abstract：:Previous studies have clearly established the down-regulating effect of a sucrose-rich diet on primary dentinogenesis in rat molars. Earlier observation of the negative effect of a high-sucrose diet on a parotid function involved in the control of intradentinal solute movement led us to hypothesize that parotid gland ...

journal_title：Journal of dental research

authors： Leonora J,Tjäderhane L,Tieche JM

更新日期：2002-04-01 00:00:00

abstract：:Twenty-two adults, considered to have high caries activity, rinsed for one yr with either SnF2 or acidulated NaF mouthrinses. Total colony-forming units and numbers of S. mutans and lactobacilli were estimated from saliva samples. Large reductions were found in the number of recoverable S. mutans in subjects rinsing w...

journal_title：Journal of dental research

authors： Tinanoff N,Klock B,Camosci DA,Manwell MA

更新日期：1983-08-01 00:00:00

abstract：:In the past two decades, accumulated evidence has clearly demonstrated the inhibitory effects of laser irradiation on enamel demineralization, but the exact mechanisms of these effects remain unclear. The purpose of this study was to investigate the effects of low-energy CO2 laser irradiation on demineralization of bo...

journal_title：Journal of dental research

authors： Hsu CY,Jordan TH,Dederich DN,Wefel JS

更新日期：2000-09-01 00:00:00

abstract：:Although the contribution of the oral microbiota to oral malodor is well-documented, the potential role of Gram-positive micro-organisms is unclear. In the current study, we tested the hypothesis that Gram-positive micro-organisms contribute to malodor production by deglycosylating oral glycoproteins, rendering them s...

journal_title：Journal of dental research

authors： Sterer N,Rosenberg M

更新日期：2006-10-01 00:00:00

abstract：:4-META and new phosphate-methacrylate resins adhere strongly to dental alloys. However, for strengthening the water durability of the adhesive interface, the oxidation of the alloy surface is indispensable. A new oxidation method using ion-sputtering was developed, and the effectiveness of this surface treatment on tw...

journal_title：Journal of dental research

authors： Tanaka T,Hirano M,Kawahara M,Matsumura H,Atsuta M

更新日期：1988-11-01 00:00:00

abstract：:Autosomal dominant mutations in PTH1R segregate with primary failure of eruption (PFE), marked by clinical eruption failure of adult teeth without mechanical obstruction. While the diagnosis of PFE conveys a poor dental prognosis, there are no reports of PFE patients who carry PTH1R mutations and exhibit any other ske...

journal_title：Journal of dental research

authors： Frazier-Bowers SA,Hendricks HM,Wright JT,Lee J,Long K,Dibble CF,Bencharit S

更新日期：2014-02-01 00:00:00

abstract：:Enamel fluorosis can occur following either an acute or chronic exposure to fluoride during tooth formation. Fluorosed enamel is characterized by a retention of amelogenins in the early-maturation stage, and by the formation of a more porous enamel with a subsurface hypomineralization. The mechanisms by which fluoride...

journal_title：Journal of dental research

authors： DenBesten PK,Thariani H

更新日期：1992-05-01 00:00:00

abstract：:Urinary catecholamines have been used to measure emotionally stressful states which may affect the development of dental caries. This study investigates the hypothesis that children with and without dental caries do not differ significantly in the mean values of urinary catecholamines such as epinephrine, norepinephri...

journal_title：Journal of dental research

authors： Vanderas AP,Manetas C,Papagiannoulis L

更新日期：1995-10-01 00:00:00

abstract：:T6 antigen is a highly specific marker for human Langerhans cells (LC). Previous studies have demonstrated that Interleukin-1 (IL-1) and an IL-1 inhibitor (ILS) modulate LC T6 expression (T6E) in explant culture. The present study examined the in vitro modulation of T6E by two molecules: epidermal-cell-derived thymocy...

journal_title：Journal of dental research

authors： Walsh LJ,Lander PE,Seymour GJ,Powell RN

更新日期：1987-03-01 00:00:00

abstract：:An indirect extrusion capillary viscometer has been developed. This has been tested for nonsetting Newtonian fluids and was found to give results close to, but slightly lower than the actual viscosity. The same apparatus has been successfully applied to a non-Newtonian fluid to determine the dependence of viscosity on...

journal_title：Journal of dental research

authors： Combe EC,Moser JB

更新日期：1976-03-01 00:00:00

abstract：:In an earlier paper on bench-scale simulation of the caries process, it was shown that the passage of ions through ion-permselective barriers could have profound effects on the composition of the solution within the "lesion" at steady state. As indicated in earlier papers, these changes are produced by unequal rates o...

journal_title：Journal of dental research

authors： Brown WE,Chow LC

更新日期：1986-09-01 00:00:00

abstract：:Moderate elevation of serum C-reactive protein (CRP) is a risk factor for cardiovascular disease among apparently healthy individuals, although factors that create this inflammatory response in the absence of systemic illness have not been clarified. This study aimed to: (1) evaluate associations among periodontal dis...

journal_title：Journal of dental research

authors： Slade GD,Offenbacher S,Beck JD,Heiss G,Pankow JS

更新日期：2000-01-01 00:00:00

abstract：:Investigators have used chemotherapeutic agents topically for plaque control without knowing the drug concentration necessary to inhibit the growth of odontopathic microorganisms. S mutans, S sanguis, A viscosus and A naeslundii are important components of the plaque flora. The minimal inhibitory concentrations (MIC) ...

journal_title：Journal of dental research

authors： Newbrun E,Felton RA,Bulkacz J

更新日期：1976-07-01 00:00:00

abstract：:It is claimed that dental fluorosis in both deciduous and permanent teeth is increasing in fluoridated and non-fluoridated communities. What is unclear is whether fluoride-induced enamel opacities in the deciduous dentition are associated with the subsequent appearance of enamel defects in the permanent dentition. The...

journal_title：Journal of dental research

authors： Milsom KM,Woodward M,Haran D,Lennon MA

更新日期：1996-04-01 00:00:00

abstract：:A procedure for measuring nasal airway resistance using posterior rhinorheometry is described. Baseline nasal airway resistances +/- 1 S.D. at an airflow of 0.5 L/sec were found to be 1.077 +/- 0.683 cm H2O for inhalation and 1.359 +/- 0.792 cm H2O for exhalation. Application of either cold water (4 to 6 C) or warm wa...

journal_title：Journal of dental research

authors： Martin JS,Tansy MF

更新日期：1977-11-01 00:00:00

abstract：:Known antimalarial compunds from several chemical classes were tested for their ability to inhibit in vitro growth of microorganisms causing dental plaque and to prevent the development of plaque in a hamster model. Approximately a third of the compounds tested inhibited in vitro growth; however, none prevented develo...

journal_title：Journal of dental research

authors： Kinnamon KE,Eckermann EH,Tempel TR,Smith JH,Wolf CR

更新日期：1975-05-01 00:00:00

abstract：:The effect of pH on the growth and proteolytic activity of the type strain and fresh isolates of Porphyromonas gingivalis and Bacteroides intermedius was investigated. B. intermedius strains grew with and without glucose at a pH as low as 5.0. These bacteria grew almost as well as Streptococcus mutans at pH 5.0 and be...

journal_title：Journal of dental research

authors： Takahashi N,Schachtele CF

更新日期：1990-06-01 00:00:00

abstract：:The biogenetic formation of mineral crystals, one aspect of biomineralization, is a multistep process of apatite formation throughout the growth of dentin tissue. An important step is the transformation of the non-mineralized predentin matrix to mineralizing dentin matrix and its biological control. In this study, the...

journal_title：Journal of dental research

authors： Wiesmann HP,Plate U,Zierold K,Höhling HJ

更新日期：1998-08-01 00:00:00

abstract：:The aim of this study was to examine the association between the bone mass (bone mineral content [BMC]) and hypomineralized second primary molars (HSPMs)/molar incisor hypomineralization (MIH) in 6-y-old children. This cross-sectional study was embedded in the Generation R Study, a population-based prospective cohort ...

journal_title：Journal of dental research

authors： van der Tas JT,Elfrink ME,Vucic S,Heppe DH,Veerkamp JS,Jaddoe VW,Rivadeneira F,Hofman A,Moll HA,Wolvius EB

更新日期：2016-04-01 00:00:00

abstract：:Catecholamines are present in saliva, but their influence on oral epithelium is not understood. Because psychological stress increases salivary catecholamines and impairs oral mucosal wound healing, we sought to determine if epithelial adrenergic signaling could link these two findings. We found that cultured human or...

journal_title：Journal of dental research

authors： Steenhuis P,Huntley RE,Gurenko Z,Yin L,Dale BA,Fazel N,Isseroff RR

更新日期：2011-02-01 00:00:00

abstract：:Candida albicans is an opportunistic fungal organism frequently detected in the oral cavity of children with severe early childhood caries (S-ECC). Previous studies suggested the cariogenic potential of C. albicans, in vitro and in vivo, and further demonstrated its synergistic interactions with Streptococcus mutans. ...

journal_title：Journal of dental research

authors： Xiao J,Grier A,Faustoferri RC,Alzoubi S,Gill AL,Feng C,Liu Y,Quivey RG,Kopycka-Kedzierawski DT,Koo H,Gill SR

更新日期：2018-12-01 00:00:00

abstract：:Four disclosant dyes were tested for antimicrobial activity against 27 oral reference strains and five non-oral human pathogens. Erythrosine and fluorescein inhibited most gram-positive and gram-negative organisms associated with dental plaque, and were bactericidal to selected strains. Fast green and brilliant blue d...

journal_title：Journal of dental research

authors： Baab DA,Broadwell AH,Williams BL

更新日期：1983-07-01 00:00:00

abstract：:Growing evidence suggests that individual genetic susceptibility may influence the host's response to infections. The aim of this project was to study whether gene polymorphisms of inflammatory markers are associated with the presence of viable periodontopathogenic bacteria. We extracted genomic DNA from 45 young adul...

journal_title：Journal of dental research

authors： Nibali L,Ready DR,Parkar M,Brett PM,Wilson M,Tonetti MS,Griffiths GS

更新日期：2007-05-01 00:00:00

abstract：:The dental pulp in human primary teeth is densely innervated by a plethora of nerve endings at the coronal pulp-dentin interface. This study analyzed how the physiological root resorption (PRR) process affects dental pulp innervation before exfoliation of primary teeth. Forty-four primary canine teeth, classified into...

journal_title：Journal of dental research

authors： Suzuki K,Lovera M,Schmachtenberg O,Couve E

更新日期：2015-10-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs (NSAIDs) are used to manage pain and inflammatory disorders. We hypothesized that gingival fibroblasts actively accumulate NSAIDs and enhance their levels in gingival connective tissue. Using fluorescence to monitor NSAID transport, we demonstrated that cultured gingival fibroblas...

journal_title：Journal of dental research

authors： Zavarella MM,Gbemi O,Walters JD

更新日期：2006-05-01 00:00:00

abstract：:Synovial hyperplasia is a feature of degenerative temporomandibular joint (TMJ) disease. However, the mechanism by which hyperplasia progresses in the TMJ is unknown. Based on the hypothesis that the oxidative stress generated by mechanical loading causes degenerative changes in the TMJ synovium, we investigated the g...

journal_title：Journal of dental research

authors： Yamaza T,Masuda KF,Atsuta I,Nishijima K,Kido MA,Tanaka T

更新日期：2004-08-01 00:00:00

abstract：:Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large...

journal_title：Journal of dental research

authors： Yamada S,Ozaki N,Tsushima K,Yamaba S,Fujihara C,Awata T,Sakashita H,Kajikawa T,Kitagaki J,Yamashita M,Yanagita M,Murakami S

更新日期：2016-08-01 00:00:00

abstract：:Phosphatases are involved in bone and tooth mineralization, but their mechanisms of action are not completely understood. Tissue-nonspecific alkaline phosphatase (TNAP, ALPL) regulates inhibitory extracellular pyrophosphate through its pyrophosphatase activity to control mineral propagation in the matrix; mice without...

journal_title：Journal of dental research

authors： McKee MD,Yadav MC,Foster BL,Somerman MJ,Farquharson C,Millán JL

更新日期：2013-08-01 00:00:00