Abstract:
:Although the occlusal vertical dimension (OVD) is strictly controlled, the neuronal mechanism of its regulation is still unclear. We hypothesize that neurons in the trigeminal mesencephalic nucleus (MesV) play an important role in the regulation of the OVD, because the MesV receives the projection from jaw-closing muscle spindles and periodontal mechanoreceptors. We measured the temporal OVD change in the guinea pig to study the effects of MesV lesions on the OVD. OVD-raised animals without MesV lesions showed a rapid OVD decrease to the same level as that in naïve controls, followed by an OVD increase after the OVD-raising appliance was removed. In contrast, OVD-raised animals with MesV lesions showed only a slight decrease in the OVD for 15 days after removal of the appliance, and then the OVD increased. The time-course of OVD development in normal-bite animals with MesV lesions was similar to that of naïve controls. These results suggest that MesV neurons are involved in OVD regulation.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Zhang W,Kobayashi M,Moritani M,Masuda Y,Dong J,Yagi T,Maeda T,Morimoto Tdoi
10.1177/154405910308200715keywords:
subject
Has Abstractpub_date
2003-07-01 00:00:00pages
565-9issue
7eissn
0022-0345issn
1544-0591journal_volume
82pub_type
杂志文章abstract::Little is known about the oral health of the frail and home-living elderly. The effects of dentogenic infections on the general condition of the elderly are also unknown. We therefore set out to investigate 191 elderly patients referred to an acute geriatric hospital due to sudden worsening of their general health. Th...
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