Abstract：
:An intra-oral model system has been developed which uses a single-section technique for before-and-after measurements on the same tissue. This model allows for placement of sections of enamel at both buccal and approximal sites. These sections may be sound or possess white-spot lesions. This allows for the evaluation of lesion initiation, lesion progression, and/or lesion remineralization. The sections are appropriate for measurement by polarized light microscopy, and, although not included in this study, they are also suitable for microradiographic evaluation. With ten human volunteers, the model system was evaluated by means of three rinse regimens in a cross-over design. The distilled water rinse showed the whole range of possible changes (e.g., demineralization, no change, and remineralization). More consistent remineralization was observed when a fluoride rinse or a remineralizing fluid was used. This model system should prove to be quite useful in evaluation of demineralization and remineralization phenomena in the oral environment.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Wefel JS,Maharry GJ,Jensen ME,Harless JDdoi
10.1177/00220345870660091401subject
Has Abstractpub_date
1987-09-01 00:00:00pages
1485-9issue
9eissn
0022-0345issn
1544-0591journal_volume
66pub_type
杂志文章abstract：:The Triggering Receptor Expressed on Myeloid cells 1 (TREM-1) is a cell-surface receptor of the immunoglobulin superfamily, involved in the propagation of the inflammatory response to bacterial challenge. Soluble (s)TREM-1 is released from the cell surface during the course of infection and is a useful inflammatory bi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034512470691
更新日期：2013-02-01 00:00:00
abstract：:Periodontitis is a chronic inflammatory disease induced by a biofilm that forms on the tooth surface. Increased periodontal disease is associated with aging. We investigated the effect of aging on challenge by oral pathogens, examining the host response, colonization, and osteoclast numbers in aged versus young mice. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515625962
更新日期：2016-04-01 00:00:00
abstract：:Teas varying in fluoride and tannin concentration were evaluated in rats for anticariogenic activity. There was a direct correlation between fluoride in tea and the inhibition of sulcal caries in rats, whereas no relationship was observed between tannin and this type of lesion. Teas also had a significant effect on ca...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630051001
更新日期：1984-05-01 00:00:00
abstract：:Conventional analyses of the cost-effectiveness of preventive regimens fail to account for the impact of attrition on reported costs. Using an economic model in which costs are allocated to fixed and variable components, and data from a recently completed clinical field trial, costs per participant are shown to vary w...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345820610050601
更新日期：1982-05-01 00:00:00
abstract：:In an attempt to determine the degree of co-activation present in selected cervical muscles during clenching, we instructed 12 male subjects to produce four brief maximum voluntary contraction (MVC) efforts (clenching) in a position of maximum intercuspation. Surface EMG activity was recorded bilaterally from the mass...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720110701
更新日期：1993-11-01 00:00:00
abstract：:Light propagation in human dentin exhibits a strong directional dependence featuring the long-known optical magnification property. We hypothesized that this anisotropic effect is caused by multiple scattering at the dentin tubules, and not by fiberoptic effects, as had been previously assumed. We performed measuremen...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910608501017
更新日期：2006-10-01 00:00:00
abstract：:Although dental amalgam is used frequently under artificial crowns for restoration of severely damaged teeth, there is little information available on the bond between luting cements and this alloy. This study was designed for determination of the strength of the bond between a dental amalgam alloy and three crown-lut...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345890680111501
更新日期：1989-11-01 00:00:00
abstract：:The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts and cementoblasts. We hypothesized that stem cells may be present in the DF and be capable of differentiating into cells of the periodontium. Stem cells ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910808700801
更新日期：2008-08-01 00:00:00
abstract：:Secondary palatogenesis occurs when the bilateral palatal shelves (PS), arising from maxillary prominences, fuse at the midline, forming the hard and soft palate. This embryonic phenomenon involves a complex array of morphogenetic events that require coordinated proliferation, apoptosis, migration, and adhesion in the...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034517726284
更新日期：2017-10-01 00:00:00
abstract：:The experiment was designed to determine the pathway taken to the brain stem by periodontal afferents responsible for the digastric jaw-opening reflex induced by tooth-tapping. Cutting the trigeminal sensory roots of anesthetized decerebrate cats eliminated the ipsilateral periodontally-induced reflex, although the st...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345870660100401
更新日期：1987-10-01 00:00:00
abstract：:The most frequent complaints registered against composite restorations are stained margins and a rough surface. The stained margins have many causes such as (1) fracturing or crazing of enamel during preparation of the cavity, (2) using a composite having an excessive curing shrinkage, (3) manipulating too slowly, whi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345790580052101
更新日期：1979-05-01 00:00:00
abstract：:Inorganic polyphosphate [Poly(P)] is especially prevalent in osteoblasts. We tested the hypothesis that Poly(P) stimulates osteoblastic differentiation and polyphosphate metabolism for bone formation. The osteoblast-like cell line, MC 3T3-E1, was cultured with Poly(P), and gene expression was evaluated by real-time re...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510363096
更新日期：2010-05-01 00:00:00
abstract：:Insulin resistance is one of the critical pathogeneses of type 2 diabetes mellitus (T2DM). Elevated levels of plasma branched-chain amino acids (BCAAs) are associated with insulin resistance. Recent studies have demonstrated the role of Porphyromonas gingivalis in the development of insulin resistance. However, the me...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520911037
更新日期：2020-07-01 00:00:00
abstract：:Inflammatory conditions as they occur during periodontal disease often result in decreased alveolar bone levels and a loss of connective tissue homeostasis. Here we have focused on the effect of microRNA-138 (miR-138) as a potential regulator of periodontal stem cells as they affect homeostasis during inflammatory con...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515613043
更新日期：2016-02-01 00:00:00
abstract：:Despite recent advances revealing genetic factors influencing caries susceptibility, questions regarding the model of inheritance involved are yet to be addressed. We conducted a Complex Segregation Analysis on decayed teeth in a sample of homogenous, isolated families recruited from the Brazilian Amazon. A dominant, ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510397614
更新日期：2011-06-01 00:00:00
abstract：:Strength and durability of the dentin-acrylic resin joint cemented with 2-cyanoacrylate esters were studied. Maximum adhesion is obtained with isobutyl 2-cyanoacrylate after 1% acid pretreatment of the dentin. Hydrolytic stability is somewhat improved by addition of polymer to the adhesive or coating around the joint....
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345790580090901
更新日期：1979-09-01 00:00:00
abstract：:Recent advances in molecular biology have facilitated analyses of the oral microbiome ("Who are they?"); however, its functions (e.g., metabolic activities) are poorly understood ("What are they doing?"). This review aims to summarize our current understanding of the metabolism of the oral microbiome. Saccharolytic ba...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034515606045
更新日期：2015-12-01 00:00:00
abstract：:15-deoxy-Delta(12,14)-prostaglandin J(2) (15-d-PGJ(2)) and troglitazone have been shown to induce apoptosis in several carcinoma cell lines. However, apoptotic signaling pathways of these agents are poorly understood. We tested the hypothesis that peroxisome proliferator-activated receptor-gamma ligands such as these ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910308201008
更新日期：2003-10-01 00:00:00
abstract：:A simple in vitro method has been described for quantitatively measuring the rate at which isotopically labeled substances permeate through dentin in occlusal cavity preparations. The presence or absence of pulp tissue had only a minor effect on the kinetics of permeation. As the dentin was made thinner there was a re...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560011601
更新日期：1977-01-01 00:00:00
abstract：:The authors tested the hypothesis that obstructive sleep apnea (OSA) signs/symptoms are associated with the occurrence of temporomandibular disorder (TMD), using the OPPERA prospective cohort study of adults aged 18 to 44 years at enrollment (n = 2,604) and the OPPERA case-control study of chronic TMD (n = 1,716). In ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513488140
更新日期：2013-07-01 00:00:00
abstract：:In previous studies, light-cured glass-ionomer cements have been shown to evoke cytotoxic reactions. It was the purpose of this investigation (a) to determine the nature of the ingredients released into an aqueous medium from 2 light-cured glass-ionomer cements (GICs) and 3 compomers; (b) to evaluate the cytotoxicity ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345980770121001
更新日期：1998-12-01 00:00:00
abstract：:Minimal invasive approaches to managing caries, such as partial caries removal techniques, are showing increasing evidence of improved outcomes over the conventional complete caries removal. There is also increasing interest in techniques where no caries is removed. We present the 1-yr results of clinical efficacy for...
journal_title：Journal of dental research
pub_type： 杂志文章,随机对照试验
doi：10.1177/0022034514550717
更新日期：2014-11-01 00:00:00
abstract：:A model system consisting of vacuum-deposited aluminum on glass was developed to demonstrate the effectiveness of cavitational activity (occurring within the cooling water supply of a dental ultrasonic scaler) in the removal of particulate material from solid surfaces. The amount of solid material removed from the mod...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630091401
更新日期：1984-09-01 00:00:00
abstract：:Mixtures containing two bacterial species were analyzed using flow cytometric techniques. Light scattering characteristics of Streptococcus mutans and Actinomyces viscosus show unique profiles for pure cultures. However, the light scatter analysis of a mixture containing these two species demonstrates overlapping near...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630080501
更新日期：1984-08-01 00:00:00
abstract：:Indigenous populations around the world experience a disproportionate burden in terms of oral diseases and conditions. These inequalities are likely due to a complex web of social determinants that includes poverty, historical consequences of colonialism, social exclusion, government policies of assimilation, cultural...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034518763605
更新日期：2018-07-01 00:00:00
abstract：:Tritiated proline was administered to domestic cats during the development of their permanent dentition. The amount of residual radioactivity was determined autoradiographically at various times after cavity preparation in mature molars and premolars. Two wk after cavity preparation, the amount of radiolabel beneath t...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345820610090101
更新日期：1982-09-01 00:00:00
abstract：:The aim of the present in vitro experiments was to determine whether the protection of enamel by topically applied fluoride against demineralization by bacterial acids would depend on the fluoride sensitivity of the bacteria. Glucose-agarose gel suspensions of fluoride-sensitive and fluoride-resistant mutans streptoco...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720080401
更新日期：1993-08-01 00:00:00
abstract：:Twenty-two adults, considered to have high caries activity, rinsed for one yr with either SnF2 or acidulated NaF mouthrinses. Total colony-forming units and numbers of S. mutans and lactobacilli were estimated from saliva samples. Large reductions were found in the number of recoverable S. mutans in subjects rinsing w...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345830620081201
更新日期：1983-08-01 00:00:00
abstract：:Inferior alveolar nerve (IAN) injury induces persistent ectopic pain which spreads to a wide area in the orofacial region. Its exact mechanism remains unclear. We investigated the involvement of nitric oxide (NO) in relation to ectopic orofacial pain caused by IAN transection (IANX). We assessed the changes in mechani...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513509280
更新日期：2013-12-01 00:00:00
abstract：:This study demonstrated a correlation between silicon x-ray counts and area fractions of adherent porcelain as determined by point-counting. This correlation has allowed a method to be devised for measuring area fractions of porcelain adherent to porcelain-fused-to-metal (PFM) fracture surfaces. The described method, ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345830620081801
更新日期：1983-08-01 00:00:00
