Economic costs of attrition in clinical trials.

abstract：:Dentinal pain in connection with mechanical stimulation i.e. probing, chiseling and initial drilling may be due to removal of fluid from the dentinal tubules. Loss of fluid due to "normal" evaporation from exposed dentin may produce an outward flow in the dentinal tubules rapid enough to cause pain and within a few mi...

journal_title：Journal of dental research

authors： Brännström M,Johnson G

更新日期：1978-01-01 00:00:00

abstract：:The expression of two matrix glycoproteins, tenascin and cellular fibronectin (cFN), has been studied in fully developed human permanent teeth, periodontal ligament, and alveolar bone, in both frozen and paraffin-processed material. Polyclonal antibodies to tenascin and a monoclonal antibody recognizing the ED sequenc...

journal_title：Journal of dental research

authors： Lukinmaa PL,Mackie EJ,Thesleff I

更新日期：1991-01-01 00:00:00

abstract：:A full understanding of the key regulators controlling periodontal development and homeostasis is necessary for the design of improved periodontal regenerative therapies. Small leucine-rich proteoglycans (SLRPs) are extracellular matrix molecules suggested to regulate collagen organization and cell signaling. Mice wit...

journal_title：Journal of dental research

authors： Wang L,Foster BL,Kram V,Nociti FH Jr,Zerfas PM,Tran AB,Young MF,Somerman MJ

更新日期：2014-08-01 00:00:00

abstract：:Although certain bacterial species appear to be risk factors for pain due to odontogenic infections, comparatively little is known about the potential mechanisms mediating this effect. In this study, we tested the hypothesis that trigeminal nociceptive neurons express the TLR4 or CD14 receptors, thus enabling sensory ...

journal_title：Journal of dental research

authors： Wadachi R,Hargreaves KM

更新日期：2006-01-01 00:00:00

abstract：:Four disclosant dyes were tested for antimicrobial activity against 27 oral reference strains and five non-oral human pathogens. Erythrosine and fluorescein inhibited most gram-positive and gram-negative organisms associated with dental plaque, and were bactericidal to selected strains. Fast green and brilliant blue d...

journal_title：Journal of dental research

authors： Baab DA,Broadwell AH,Williams BL

更新日期：1983-07-01 00:00:00

abstract：:The efficacy of a new remineralization system was determined in vivo by maintaining a low concentration of approximately 1 ppm fluoride for 48 hrs against a demineralized human tooth. Human subjects were selected who wore removable partial dentures containing two or more of the demineralized teeth with film system. Th...

journal_title：Journal of dental research

authors： Abrahams LJ,Yonese M,Higuchi WI,Fox JL,Charbeneau GT

更新日期：1980-03-01 00:00:00

abstract：:In an earlier paper on bench-scale simulation of the caries process, it was shown that the passage of ions through ion-permselective barriers could have profound effects on the composition of the solution within the "lesion" at steady state. As indicated in earlier papers, these changes are produced by unequal rates o...

journal_title：Journal of dental research

authors： Brown WE,Chow LC

更新日期：1986-09-01 00:00:00

abstract：:Physico-chemical investigations of enamel from deciduous teeth of a small number of children with and without pre-natal fluoride supplementation (PNF) exhibited the following differences between the PNF and non-PNF enamel, with the former showing: (a) more homogeneous and less extensive patterns of acid-etching; (b) d...

journal_title：Journal of dental research

authors： LeGeros RZ,Glenn FB,Lee DD,Glenn WD

更新日期：1985-03-01 00:00:00

abstract：:The aim of this study was to determine whether the parotid gland, like other salivary glands, produces blood group antigens. A post-embedding immunogold staining (IGS) method for ABH antigens was applied to osmicated and nonosmicated, routinely prepared specimens of normal human parotid glands. A and B antigens were n...

journal_title：Journal of dental research

authors： Lantini MS,Cossu M

更新日期：1994-02-01 00:00:00

abstract：:Dietary components rich in polyphenols-for example, tea and red wine-are thought to cause tooth staining. In the present study, hydroxyapatite was used as a model of enamel for study of the influence of salivary proteins on the binding of different polyphenols to hydroxyapatite in vitro. Neither salivary protein pelli...

journal_title：Journal of dental research

authors： Proctor GB,Pramanik R,Carpenter GH,Rees GD

更新日期：2005-01-01 00:00:00

abstract：:The effect of enamel matrix proteins on the seeded growth of enamel apatite crystals was studied in stable supersaturated solutions at pH 7.4 and 37 degrees C. Of the two major protein classes in the enamel matrix, the enamelins were considerably more effective than the amelogenins in retarding seeded growth. However,...

journal_title：Journal of dental research

authors： Doi Y,Eanes ED,Shimokawa H,Termine JD

更新日期：1984-02-01 00:00:00

abstract：:Mucous membrane pemphigoid or cicatricial pemphigoid is a mucocutaneous blistering disease characterized by autoantibodies to different molecules in the basement membrane zone. Our objectives were to identify the target antigen recognized by sera from 20 untreated patients with pemphigoid disease limited to the oral c...

journal_title：Journal of dental research

authors： Bhol KC,Goss L,Kumari S,Colon JE,Ahmed AR

更新日期：2001-08-01 00:00:00

abstract：:It has often been hypothesized that a large tongue leads to an enlargement of the mandible and therefore contributes to the development of mandibular prognathism. We examined (1) whether the tongue volume in human subjects with mandibular prognathism was larger than that in subjects with good occlusion and (2) whether...

journal_title：Journal of dental research

authors： Yoo E,Murakami S,Takada K,Fuchihata H,Sakuda M

更新日期：1996-12-01 00:00:00

abstract：:A gravity sintering fabrication technique has been developed for producing Co-Cr-Mo alloy dental implants having a porous coating on the root portion. This process allows for control of pore structure enabling ingrowth of either bone or fibrous tissue. The microstructure and mechanical properties of these materials ha...

journal_title：Journal of dental research

authors： Klawitter JJ,Weinstein AM,Peterson LJ

更新日期：1977-05-01 00:00:00

abstract：:The experiment was designed to determine the pathway taken to the brain stem by periodontal afferents responsible for the digastric jaw-opening reflex induced by tooth-tapping. Cutting the trigeminal sensory roots of anesthetized decerebrate cats eliminated the ipsilateral periodontally-induced reflex, although the st...

journal_title：Journal of dental research

authors： Collier TG,Lund JP

更新日期：1987-10-01 00:00:00

abstract：:A model system consisting of vacuum-deposited aluminum on glass was developed to demonstrate the effectiveness of cavitational activity (occurring within the cooling water supply of a dental ultrasonic scaler) in the removal of particulate material from solid surfaces. The amount of solid material removed from the mod...

journal_title：Journal of dental research

authors： Walmsley AD,Laird WR,Williams AR

更新日期：1984-09-01 00:00:00

abstract：:Pulpal blood flow was determined in 32 dogs ranging in age from 6 weeks to 18 months by the isotope fractionation method incorporating diffusible and nondiffusible tracers. Dogs were placed into selected age groups by the developmental status of the canine teeth. For the teeth sampled, the maxillary first, second, and...

journal_title：Journal of dental research

authors： Path MG,Meyer MW

更新日期：1977-10-01 00:00:00

abstract：:Since edentate subjects have a reduced masticatory function, it can be expected that the morphology of the cancellous bone of their mandibular condyles has changed according to the altered mechanical environment. In the present study, the morphology of cylindrical cancellous bone specimens of the mandibular condyles o...

journal_title：Journal of dental research

authors： Giesen EB,Ding M,Dalstra M,van Eijden TM

更新日期：2004-03-01 00:00:00

abstract：:This study demonstrated a correlation between silicon x-ray counts and area fractions of adherent porcelain as determined by point-counting. This correlation has allowed a method to be devised for measuring area fractions of porcelain adherent to porcelain-fused-to-metal (PFM) fracture surfaces. The described method, ...

journal_title：Journal of dental research

authors： Ringle RD,Mackert JR Jr,Fairhurst CW

更新日期：1983-08-01 00:00:00

abstract：:Greater fluoride concentrations were obtained in enamel treated with phosphate/fluoride solutions than in that treated with TiF4 at similar pH's (1.0) and F concentrations (0.6M F and 1.6M F). However, fluoride solution without added phosphate at pH 1.0 and 1.6M F concentration produced lower fluoride concentrations i...

journal_title：Journal of dental research

authors： Clarkson B,Wefel J

更新日期：1979-02-01 00:00:00

abstract：:The benefits of early orthodontic treatment are continuously discussed, but studies are few. We examined whether definite need for orthodontic treatment could be eliminated in public health care by systematically focusing on early intervention. One age cohort living in a rural Finnish municipality (N = 85) was regular...

journal_title：Journal of dental research

authors： Kerosuo H,Väkiparta M,Nyström M,Heikinheimo K

更新日期：2008-06-01 00:00:00

abstract：:Evidence that dental status affects diet is equivocal. The hypothesis of this study was that diet was affected by dental status. The objective was to assess the relationship between numbers of teeth and diet and nutritional status in US adult civilians without prostheses. We examined 6985 NHANES (1988-1994) participan...

journal_title：Journal of dental research

authors： Nowjack-Raymer RE,Sheiham A

更新日期：2007-12-01 00:00:00

abstract：:The dental pulp in human primary teeth is densely innervated by a plethora of nerve endings at the coronal pulp-dentin interface. This study analyzed how the physiological root resorption (PRR) process affects dental pulp innervation before exfoliation of primary teeth. Forty-four primary canine teeth, classified into...

journal_title：Journal of dental research

authors： Suzuki K,Lovera M,Schmachtenberg O,Couve E

更新日期：2015-10-01 00:00:00

abstract：:Blood cortisol levels of oral surgery patients were analyzed to objectively determine the effect of intravenous sedation on surgical stress. Results showed a measure of sedation but did not adequately reflect the stress of oral surgery or the changes produced by intravenous sedation. ...

journal_title：Journal of dental research

authors： Bunch FL,Allen GD,Jorgensen NB

更新日期：1975-09-01 00:00:00

abstract：:Previous studies of tooth size in twins and their families have suggested a high degree of genetic control, although there have been difficulties separating the various genetic and environmental effects. A genetic analysis of variation in crown size of the permanent incisors of South Australian twins was carried out, ...

journal_title：Journal of dental research

authors： Dempsey PJ,Townsend GC,Martin NG,Neale MC

更新日期：1995-07-01 00:00:00

abstract：:A water-soluble lipopolysaccharide from Salmonella enteritidis and a phenol-soluble lipopolysaccharide from Leptotrichia buccalis were applied topically to the healthy marginal gingivae of beagle dogs. Saline was applied to contralateral areas as an internal control. Increases in vascular permeability were monitored b...

journal_title：Journal of dental research

authors： Montgomery EH,White RR

更新日期：1986-02-01 00:00:00

abstract：:The intent of this article is to review the numerous factors that affect the mechanical properties of particle- or fiber-filler-containing indirect dental resin composite materials. The focus will be on the effects of degradation due to aging in different media, mainly water and water and ethanol, cyclic loading, and ...

journal_title：Journal of dental research

authors： Drummond JL

更新日期：2008-08-01 00:00:00

abstract：:Mixed or parotid saliva from caries-active individuals consistently supported better growth of Streptococcus mutans (type c) than that from caries-free individuals. Electrophoretic studies revealed that certain proteins in caries-active salivas were susceptible to microbial attack, but similar proteins in caries-free ...

journal_title：Journal of dental research

authors： Cowman RA,Schaefer SJ,Fitzgerald RJ,Rosner D,Shklair IL,Walter RG

更新日期：1979-10-01 00:00:00

abstract：:To understand the role of betel quid (BQ) in the pathogenesis of oral submucous fibrosis (OSF) and oral cancer, we used DNA damage, cytotoxicity, and cell proliferation assays to study the pathobiological effects of aqueous extracts of three BQ constituents [betel nut (Areca catechu, BN), inflorescence of Piper betle ...

journal_title：Journal of dental research

authors： Jeng JH,Kuo ML,Hahn LJ,Kuo MY

更新日期：1994-05-01 00:00:00

abstract：:The biogenetic formation of mineral crystals, one aspect of biomineralization, is a multistep process of apatite formation throughout the growth of dentin tissue. An important step is the transformation of the non-mineralized predentin matrix to mineralizing dentin matrix and its biological control. In this study, the...

journal_title：Journal of dental research

authors： Wiesmann HP,Plate U,Zierold K,Höhling HJ

更新日期：1998-08-01 00:00:00