A major gene effect controls resistance to caries.

abstract：:Fibroblast cultures derived from uninjured and reparative rabbit buccal mucosa were compared in terms of extracellular glycosaminoglycan (GAG) content and cellular response to interleukin-1 (IL-1). Under identical growth conditions, proliferation of both cell lines was the same. Both lines incorporated [3H]-glucosamin...

journal_title：Journal of dental research

authors： Bronson RE,Treat JA,Bertolami CN

更新日期：1989-01-01 00:00:00

abstract：:Strength and durability of the dentin-acrylic resin joint cemented with 2-cyanoacrylate esters were studied. Maximum adhesion is obtained with isobutyl 2-cyanoacrylate after 1% acid pretreatment of the dentin. Hydrolytic stability is somewhat improved by addition of polymer to the adhesive or coating around the joint....

journal_title：Journal of dental research

authors： Brauer GM,Jackson JA,Termini DJ

更新日期：1979-09-01 00:00:00

abstract：:The treatment of periodontitis/peri-implantitis involves the reduction/eradication of periopathogens. After therapy, beneficial and pathogenic species recolonize the subgingival area. The dynamics of recolonization and especially the role of the supragingival environment in this process are still not well-understood. ...

journal_title：Journal of dental research

authors： Quirynen M,Vogels R,Pauwels M,Haffajee AD,Socransky SS,Uzel NG,van Steenberghe D

更新日期：2005-04-01 00:00:00

abstract：:In two separate experiments, none of the 14 subunits examined consistently ranked dentifrices similarly to the ranking obtained when the individual rat was used as the experimental unit. Arbitrarily dividing the rat into subunits and then comparing results among these subunits may lead to false conclusions since the r...

journal_title：Journal of dental research

authors： Briner WW

更新日期：1976-05-01 00:00:00

abstract：:An oral radiotelemetric technique was used to determine whether a range of efficient buffers had the capacity to control the levels of hydrogen ions within dental plaque in the presence of sucrose. It was found that the buffers failed to control both the intensity and duration of the acid produced. ...

journal_title：Journal of dental research

authors： Clarke NG,Dowdell LR

更新日期：1976-09-01 00:00:00

abstract：:The purpose of this study was to determine the surface roughness of enamel-to-enamel contact areas in order to provide a standard for comparison with surface characteristics of commercially available composite restorative materials. In addition, the inherent surface roughness of resin composites was evaluated profilom...

journal_title：Journal of dental research

authors： Willems G,Lambrechts P,Braem M,Vuylsteke-Wauters M,Vanherle G

更新日期：1991-09-01 00:00:00

abstract：:Tooth enamel is the most highly mineralized tissue in vertebrates. Enamel crystal formation and elongation should be well controlled to achieve an exceptional hardness and a compact microstructure. Enamel matrix calcification occurs with several matrix proteins, such as amelogenin, enamelin, and ameloblastin. Among th...

journal_title：Journal of dental research

authors： Cho ES,Kim KJ,Lee KE,Lee EJ,Yun CY,Lee MJ,Shin TJ,Hyun HK,Kim YJ,Lee SH,Jung HS,Lee ZH,Kim JW

更新日期：2014-10-01 00:00:00

abstract：:Modulation of the phosphoinositide signal transduction pathway by arachidonic acid (AA) in collagenase-dispersed rat submandibular acinar cells was investigated. The muscarinic agonist, carbachol, stimulated PIP2 hydrolysis and the generation of IP3 to five-fold the control levels. This response was inhibited by 75% o...

journal_title：Journal of dental research

authors： Chung HC,Fleming N

更新日期：1992-08-01 00:00:00

abstract：:The synthesis of many polycarboxylic acids is reported. An account is given of their stability in aqueous solution and the properties of cements formed by their reaction with ion-leachable glasses. A copolymer of acrylic and itaconic acids was found to combine several favorable characteristics. ...

journal_title：Journal of dental research

authors： Crisp S,Kent BE,Lewis BG,Ferner AJ,Wilson AD

更新日期：1980-06-01 00:00:00

abstract：:The aim of this meta-analysis was to examine the clinical effectiveness of miniscrew implants (MI) used for anchorage reinforcement compared with that of conventional orthodontic means, as well as to assess the success rates of MIs and the possible risk factors affecting their clinical effectiveness. Literature search...

journal_title：Journal of dental research

authors： Papadopoulos MA,Papageorgiou SN,Zogakis IP

更新日期：2011-08-01 00:00:00

abstract：:Lingual amylase and lingual lipase, two digestive enzymes that are secreted from lingual serous glands (von Ebner's), were simultaneously purified from rat lingual serous glands with hydrophobic chromatography used as the final step. This method, previously developed for the purification of lingual lipase, includes ho...

journal_title：Journal of dental research

authors： Field RB,Spielman AI,Hand AR

更新日期：1989-02-01 00:00:00

abstract：:Candida albicans is an opportunistic fungal organism frequently detected in the oral cavity of children with severe early childhood caries (S-ECC). Previous studies suggested the cariogenic potential of C. albicans, in vitro and in vivo, and further demonstrated its synergistic interactions with Streptococcus mutans. ...

journal_title：Journal of dental research

authors： Xiao J,Grier A,Faustoferri RC,Alzoubi S,Gill AL,Feng C,Liu Y,Quivey RG,Kopycka-Kedzierawski DT,Koo H,Gill SR

更新日期：2018-12-01 00:00:00

abstract：:The eventual outcome of dental caries is determined by the dynamic balance between pathological factors that lead to demineralization and protective factors that lead to remineralization. Pathological factors include acidogenic bacteria, inhibition of salivary function, and frequency of ingestion of fermentable carboh...

journal_title：Journal of dental research

authors： Featherstone JD

更新日期：2004-01-01 00:00:00

abstract：:Tooth agenesis is one of the most common developmental anomalies affecting function and esthetics. The paired-domain transcription factor, Pax9, is critical for patterning and morphogenesis of tooth and taste buds. Mutations of PAX9 have been identified in patients with tooth agenesis. Despite significant progress in ...

journal_title：Journal of dental research

authors： Wong SW,Han D,Zhang H,Liu Y,Zhang X,Miao MZ,Wang Y,Zhao N,Zeng L,Bai B,Wang YX,Liu H,Frazier-Bowers SA,Feng H

更新日期：2018-02-01 00:00:00

abstract：:Enamel abraders used in two-body wear tests suffer the disadvantage that standardization is difficult or impossible to obtain. The aim of this study was to test whether steatite (a ceramic material with a Vickers Hardness similar to that of enamel) could be used as a satisfactory human enamel analogue. The friction an...

journal_title：Journal of dental research

authors： Wassell RW,McCabe JF,Walls AW

更新日期：1994-09-01 00:00:00

abstract：:Macrophage colony-stimulating factor (CSF-1) is a key regulatory cytokine for amelogenesis, and ameloblasts synthesize CSF-1. We hypothesized that PDGF stimulates DNA synthesis and regulates CSF-1 in these cells. We determined the effect of PDGF on CSF-1 expression using MEOE-3M ameloblasts as a model. By RT-PCR, MEOE...

journal_title：Journal of dental research

authors： Wittrant Y,Bhandari BS,Abboud H,Benson N,Woodruff K,MacDougall M,Abboud-Werner S

更新日期：2008-01-01 00:00:00

abstract：:Cell kinetics of rat molar periodontal ligament (PDL) during orthodontically-induced osteogenesis revealed: 1) primary growth fraction of 59%, 2) proliferating cells from throughout the PDL migrate toward the bone surface, 3) preosteoblasts, capable of forming osteoblasts without synthesizing DNA, are present in the P...

journal_title：Journal of dental research

authors： Roberts WE,Chase DC

更新日期：1981-02-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) plays a crucial role in the modulation of orofacial pain, and we hypothesized that CGRP mediated a neuron-glia crosstalk in orofacial pain. The objective of this study was to elucidate the mechanisms whereby CGRP mediated trigeminal neuron-glia crosstalk in modulating orofacial p...

journal_title：Journal of dental research

authors： Liang H,Hu H,Shan D,Lyu J,Yan X,Wang Y,Jian F,Li X,Lai W,Long H

更新日期：2021-01-01 00:00:00

abstract：:Defects in the enamelin gene (ENAM) cause amelogenesis imperfecta (AI). Our objective was to identify the genetic etiology of enamel hypoplasia in a Caucasian proband. Our hypothesis was that ENAM was defective. The proband and his father have an AG insertion (g.13185_13186insAG; p.422FsX448) in ENAM previously identi...

journal_title：Journal of dental research

authors： Chan HC,Mai L,Oikonomopoulou A,Chan HL,Richardson AS,Wang SK,Simmer JP,Hu JC

更新日期：2010-07-01 00:00:00

abstract：:Minimizing patient exposure while maintaining a diagnostically acceptable radiograph is a major goal in diagnostic radiography. Rare-earth filters may be the means to achieve this goal due to their "band-pass effect". The purpose of this study was to examine the image contrast effects and exposure reductions for vario...

journal_title：Journal of dental research

authors： Mauriello SM,Washburn DB,Matteson SR

更新日期：1987-08-01 00:00:00

abstract：:The presence and kinetics of bone-resorbing activity in periapical lesions were studied with a rat model system. Lesions were found to expand most rapidly between induction on day 0 and day 15 ("active phase"), with enlargement occurring at a slower rate thereafter (days 20 and 30, "chronic phase"), as assessed by mea...

journal_title：Journal of dental research

authors： Wang CY,Stashenko P

更新日期：1991-10-01 00:00:00

abstract：:Because of the greater sensitivity of commonly used dental films near 40 kv and the inherently greater contrast between bone and other oral tissues that is achieved at lower energies than those conventionally used, a considerable reduction of radiation exposure can be obtained by the use of those quasimonochromatic ph...

journal_title：Journal of dental research

authors： Huen A,Sternglass EJ,Mazzocco DM,Fischer WG

更新日期：1976-01-01 00:00:00

abstract：:The surface enamel of fetal bovine teeth was stained with GBHA to indicate the position of bands of smooth-ended and ruffle-ended ameloblasts relative to the developing enamel. The boundaries of the bands were scored, under a dissecting microscope, and the bulk enamel under each band was collected. The enamel samples ...

journal_title：Journal of dental research

authors： Bawden JW,Keels MA,Deaton TG,Crenshaw MA

更新日期：1988-06-01 00:00:00

abstract：:Oxygen inhibits free radical polymerization and yields polymers with uncured surfaces. This is a concern when thin layers of resin are being polymerized, or in circumstances where conventional means of eliminating inhibition are inappropriate. In this study, we tested the hypothesis that viscosity, filler content, and...

journal_title：Journal of dental research

authors： Gauthier MA,Stangel I,Ellis TH,Zhu XX

更新日期：2005-08-01 00:00:00

abstract：:Tempering of dental porcelain by forced convective cooling in air has been shown previously to inhibit the sizes of cracks induced in porcelain surfaces. However, the depth of compressive stress that is produced by tempering of feldspathic porcelain has not been determined. It can be assumed that the potential of temp...

journal_title：Journal of dental research

authors： Anusavice KJ,Gray A,Shen C

更新日期：1991-02-01 00:00:00

abstract：:Extracellular matrix (ECM) mineralization is regulated by mineral ion availability, proteins, and other molecular determinants. To investigate protein regulation of mineralization in tooth dentin and cementum, and in alveolar bone, we expressed matrix Gla protein (MGP) ectopically in bones and teeth in mice, using an ...

journal_title：Journal of dental research

authors： Kaipatur NR,Murshed M,McKee MD

更新日期：2008-09-01 00:00:00

abstract：:Periostin is a mesenchymal cell marker predominantly expressed in collagen-rich fibrous connective tissues, including heart valves, tendons, perichondrium, periosteum, and periodontal ligament (PDL). Knockdown of periostin expression in mice results in early-onset periodontitis and failure of cardiac healing after acu...

journal_title：Journal of dental research

authors： Yamada S,Tauchi T,Awata T,Maeda K,Kajikawa T,Yanagita M,Murakami S

更新日期：2014-09-01 00:00:00

abstract：:A model system consisting of vacuum-deposited aluminum on glass was developed to demonstrate the effectiveness of cavitational activity (occurring within the cooling water supply of a dental ultrasonic scaler) in the removal of particulate material from solid surfaces. The amount of solid material removed from the mod...

journal_title：Journal of dental research

authors： Walmsley AD,Laird WR,Williams AR

更新日期：1984-09-01 00:00:00

abstract：:The balance between bone resorption and bone formation is vital for maintenance and regeneration of alveolar bone and supporting structures around teeth and dental implants. Tissue regeneration in the oral cavity is regulated by multiple cell types, signaling mechanisms, and matrix interactions. A goal for periodontal...

journal_title：Journal of dental research

authors： Larsson L,Decker AM,Nibali L,Pilipchuk SP,Berglundh T,Giannobile WV

更新日期：2016-03-01 00:00:00

abstract：:Previous studies have suggested that information provided by periodontal mechanoreceptors is particularly important for the fine motor control of the mandible, i.e., when humans hold and carefully manipulate food particles between the teeth with low biting forces. In the present study, we further evaluated this hypoth...

journal_title：Journal of dental research

authors： Trulsson M,Gunne HS

更新日期：1998-04-01 00:00:00