Abstract:
:The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts and cementoblasts. We hypothesized that stem cells may be present in the DF and be capable of differentiating into cells of the periodontium. Stem cells were identified in the DF of the rat first mandibular molar by Hoechst staining, alkaline phosphatase staining, and expression of side-population stem cell markers. These cells were shown to be able to differentiate into osteoblasts/cementoblasts, adipocytes, and neurons. Treating the DF cell population with doxorubicin, followed by incubation in an adipogenesis medium, suggested that the adipocytes originated from stem cells. Thus, a possibly puripotent stem cell population is present in the rat DF.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Yao S,Pan F,Prpic V,Wise GEdoi
10.1177/154405910808700801subject
Has Abstractpub_date
2008-08-01 00:00:00pages
767-71issue
8eissn
0022-0345issn
1544-0591pii
87/8/767journal_volume
87pub_type
杂志文章abstract::Previous reports have linked the prevalence of tooth abnormalities with high caries experience in the different types of epidermolysis bullosa (EB). However, it is not known to what extent the apparent susceptibility to enamel caries is due to disease-related altered enamel chemistry in these cases. The aim of this st...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750090901
更新日期:1996-09-01 00:00:00
abstract::The remodeling of gingival tissue was measured by determining the incorporation of tritiated proline and the disappearance of tritium activity from proline and hydroxyproline for 18 days after administration of label. There was a rapid decrease in the tritium activity from gingiva which was paralleled by a decrease in...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345780570023101
更新日期:1978-02-01 00:00:00
abstract::Wavelength-independent Microradiography (WIM), described in this paper, used polychromatic, high-energy (less than or equal to 60 kV) x-rays for determination of mineral concentrations in tooth material non-destructively. This was done with the aid of a reference step-wedge made of 94% aluminum, 6% zinc. The mass atte...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345900690081501
更新日期:1990-08-01 00:00:00
abstract::The benefits of early orthodontic treatment are continuously discussed, but studies are few. We examined whether definite need for orthodontic treatment could be eliminated in public health care by systematically focusing on early intervention. One age cohort living in a rural Finnish municipality (N = 85) was regular...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700604
更新日期:2008-06-01 00:00:00
abstract::The Global Burden of Disease (GBD) 2010 Study produced comparable estimates of the burden of 291 diseases and injuries in 1990, 2005, and 2010. This article reports on the global burden of untreated caries, severe periodontitis, and severe tooth loss in 2010 and compares those figures with new estimates for 1990. We u...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513490168
更新日期:2013-07-01 00:00:00
abstract:UNLABELLED:The aim of this observational study was to investigate the features of the chewing activity and the variability of the human chewing pace, as assessed in the natural environment. It was hypothesized that the chewing pace is relatively constant within individuals across different days but is variable across i...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034511416669
更新日期:2011-10-01 00:00:00
abstract::Physico-chemical investigations of enamel from deciduous teeth of a small number of children with and without pre-natal fluoride supplementation (PNF) exhibited the following differences between the PNF and non-PNF enamel, with the former showing: (a) more homogeneous and less extensive patterns of acid-etching; (b) d...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345850640031601
更新日期:1985-03-01 00:00:00
abstract::Stem cells are remarkable, and stem cell-based tissue engineering is an emerging field of biomedical science aiming to restore damaged tissue or organs. In dentistry and reconstructive facial surgery, it is of great interest to restore lost teeth or craniofacial bone defects using stem cell-mediated therapy. In the cr...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034515603972
更新日期:2015-11-01 00:00:00
abstract::Although the tripeptides Glu-O-Phosphoserine-Tyr and Glu-O-Phosphoserine-Leu have been identified in embryonic bovine enamel proteins, 1, 2 the issue of whether both sequences occur in each of the phosphopeptides, or whether certain sequences occur in specific peptides only, has recently been resolved by isolating hom...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580023101
更新日期:1979-03-01 00:00:00
abstract::Adenoviral vectors effectively transfer genes to rat salivary glands. However, potent immune responses limit their use in vivo. Mice offer more opportunities than rats for the study of these immune processes. We first established conditions for infection of mouse salivary glands, with an adenoviral vector. The effects...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790020201
更新日期:2000-02-01 00:00:00
abstract::Because of the greater sensitivity of commonly used dental films near 40 kv and the inherently greater contrast between bone and other oral tissues that is achieved at lower energies than those conventionally used, a considerable reduction of radiation exposure can be obtained by the use of those quasimonochromatic ph...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550010801
更新日期:1976-01-01 00:00:00
abstract::Adhesion of restorative and protective materials to dentin is an important requirement for operative and preventive dentistry. Wettability and roughness are dentin substrate conditions that are critical to establishing good adhesion. This study examined superficial and deep dentin for variations in water contact angle...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345990780091001
更新日期:1999-09-01 00:00:00
abstract::Recent functional animal studies have reported that the motor control of masticatory muscle function is bilaterally guided by both hemispheres, which may fundamentally differ from the cortical control of limb muscle function. In this study, we investigated whether unilateral cortical brain infarction induces different...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345990780120701
更新日期:1999-12-01 00:00:00
abstract::Van der Woude syndrome (VWS) is an autosomal-dominant oral facial disorder. To find a gene mutation in a Japanese family using fingernail DNA samples, we performed this study. We hypothesized that a gene mutation in IRF6 might be involved in VWS, and that fingernail DNA samples may be valuable for detecting such mutat...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608501215
更新日期:2006-12-01 00:00:00
abstract::Decisions to replace existing restorations are often based on clinical findings of margin discrepancies and other restoration defects. Previous studies have suggested that such findings do not correlate well with the actual presence of secondary caries, and that treatment should be deferred until caries is clinically ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720121301
更新日期:1993-12-01 00:00:00
abstract::The mechanism of formation of nodular material on the surface of a Pd-Ag-based alloy for porcelain during pre-porcelainization heat treatment was investigated using scanning electron microscopy, x-ray diffraction, quantitative metallography, and Auger electron spectroscopy. The nodules were found to form by a Nabarro-...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620121201
更新日期:1983-12-01 00:00:00
abstract::Evidence that dental status affects diet is equivocal. The hypothesis of this study was that diet was affected by dental status. The objective was to assess the relationship between numbers of teeth and diet and nutritional status in US adult civilians without prostheses. We examined 6985 NHANES (1988-1994) participan...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708601206
更新日期:2007-12-01 00:00:00
abstract::We have previously reported the clinical and radiographic findings of a trial in dogs of a new dental implant system after a functional period of eight months. The present report consists of the corresponding qualitative and quantitative histological data. The implant system was fabricated from Ti-6A1-4V and employed ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670090801
更新日期:1988-09-01 00:00:00
abstract::Bacteroides forysthus has been shown to be prevalent among patients with periodontitis. Conventional microbiological methods used to identify this bacterium, however, are laborious and time-consuming and are therefore not well-suited for screening purposes. We have developed a polymerase chain-reaction (PCR) method wh...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760070701
更新日期:1997-07-01 00:00:00
abstract::Dental diseases are now viewed as a consequence of a deleterious shift in the balance of the normally stable resident oral microbiome. It is known that frequent carbohydrate consumption or reduced saliva flow can lead to caries, and excessive plaque accumulation increases the risk of periodontal diseases. However, whe...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034517742139
更新日期:2018-04-01 00:00:00
abstract::The amount of free water in 50 samples of air-dried enamel from permanent and deciduous teeth was measured by the Karl Fischer method. Samples included both contemporary and burial specimens. The mean values obtained showed that free water constituted about 1% of enamel mass. However, the range of individual values va...
journal_title:Journal of dental research
pub_type: 历史文章,杂志文章
doi:10.1177/00220345880670051701
更新日期:1988-05-01 00:00:00
abstract::Schoolchildren residing in a fluoride-deficient area were provided either a sodium fluoride (0.1% F) or a nonfluoride dentifrice for home use. About half the children provided each type of dentifrice were also given an initial prophylaxis. Combining the data with regard to the type of dentifrice indicated that the sod...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/00220345750540013601
更新日期:1975-01-01 00:00:00
abstract::Previous studies have shown that therapeutic pulsed ultrasound (pulsed) has superior stimulatory effect on bone fracture healing compared with continuous ultrasound (continuous). Our predictive hypothesis was that pulsed ultrasound can produce better bone formation during mandibular osteodistraction than continuous ul...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808701018
更新日期:2008-10-01 00:00:00
abstract::The anticaries effect of professional fluoride (F) application has been attributed to calcium-fluoride-like deposits (CaF(2)) formed on enamel, but this has not been clearly demonstrated. We hypothesized that CaF(2) formed on plaque-free enamel by F application would reduce enamel demineralization due to the increase ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808701105
更新日期:2008-11-01 00:00:00
abstract::Successive active phases observed in periodontal diseases may be explained either by a sudden activation of the pro-forms of tissue-stored degradative enzymes such as metalloproteinases (MMPs) or by an imbalance between metalloproteinases and their tissue inhibitors (TIMPs). To discriminate between these two hypothese...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::In the past two decades, accumulated evidence has clearly demonstrated the inhibitory effects of laser irradiation on enamel demineralization, but the exact mechanisms of these effects remain unclear. The purpose of this study was to investigate the effects of low-energy CO2 laser irradiation on demineralization of bo...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790091401
更新日期:2000-09-01 00:00:00
abstract::Six subjects wore intra-oral devices carrying eight bovine enamel blocks which were covered with a layer of S. mutans. They rinsed their mouths for five sec, one min, or multiples of one min with a 5 or 10% glucose (G) solution. Demineralization was measured after 45 min by determining the change in iodide permeabilit...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650021001
更新日期:1986-02-01 00:00:00
abstract::Hereditary diseases affecting the skeleton are heterogeneous in etiology and severity. Though many of these conditions are individually rare, the total number of people affected is great. These disorders often include dental-oral-craniofacial (DOC) manifestations, but the combination of the rarity and lack of in-depth...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034514529150
更新日期:2014-07-01 00:00:00
abstract::Previous findings from studies utilizing human labial and palatine minor salivary glands are reviewed. These studies took histopathological, biochemical, and ultrastructural approaches, and focused on control and diseased glands. Disease-oriented summarization are used, and control results are discussed in the context...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660s108
更新日期:1987-02-01 00:00:00
abstract::Two copper-free amalgams expanded excessively after storage in air at 60 degrees C for about five yr. One expanded significantly at 37 degrees C and slightly at 23 degrees C. High silver content, absence of copper, and presence of small amounts of zinc, or all three, seemed to promote very high expansions at 60 degree...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345820610063301
更新日期:1982-06-01 00:00:00