Stem Cells in Teeth and Craniofacial Bones.

abstract：:The effect of inflammation on the distribution of chondroitin sulfate and dermatan sulfate proteoglycans was assessed after normal and inflamed human gingivae were stained with monoclonal antibodies against these extracellular matrix macromolecules. The tissues were obtained following periodontal surgery and reacted w...

journal_title：Journal of dental research

authors： Bartold PM

更新日期：1992-09-01 00:00:00

abstract：:Artificial white spot lesions have been prepared on bovine enamel surfaces by the controlled addition of lactate buffer containing methylhydroxydiphosphonate ions. The rates of remineralization have been measured using a constant composition method in solutions of calcium phosphate of low supersaturation. Deposition o...

journal_title：Journal of dental research

authors： de Rooij JF,Nancollas GH

更新日期：1984-06-01 00:00:00

abstract：:Synovitis in internal derangement of the temporomandibular joint (TMJ) is accompanied by the growth of new blood vessels. Fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor (VEGF) are well-characterized angiogenic factors. The objective of this study was to elucidate the correlation between the ...

journal_title：Journal of dental research

authors： Sato J,Segami N,Yoshitake Y,Nishikawa K

更新日期：2003-04-01 00:00:00

abstract：:Teeth develop through distinct morphological stages. At the cap stage, a compactly clustered and concentrically arranged cell mass, the enamel knot, appears at the tip of the enamel organ. Cells in this knot express sets of key molecules, and as such have been proposed to act as a signaling center directing tooth morp...

journal_title：Journal of dental research

authors： Liu M,Zhao S,Wang XP

更新日期：2014-05-01 00:00:00

abstract：:Cell therapies utilizing mesenchymal stem cells (MSCs) could overcome limitations of traditional treatments for reconstructing craniofacial tissues. This large-scale study explored a standardized methodology for the isolation and clinical-scale expansion of alveolar bone marrow-derived MSCs (aBMSCs). We harvested 103 ...

journal_title：Journal of dental research

authors： Mason S,Tarle SA,Osibin W,Kinfu Y,Kaigler D

更新日期：2014-01-01 00:00:00

abstract：:Sensory, sympathetic and parasympathetic ganglia located in the head and neck of rhesus monkeys were histologically examined after injection of H3-HRP into the right mandibular premolars and molars. The results showed positive labeling of ganglionic cell bodies located in the ipsilateral trigeminal, superior cervical,...

journal_title：Journal of dental research

authors： Chiego DJ Jr,Cox CF,Avery JK

更新日期：1980-04-01 00:00:00

abstract：:This study describes the formation of a calcium polyacrylate-hydroxyapatite cement. Our hypothesis was that calcium phosphates would rapidly hydrolyze in the presence of polyacrylic acid (PAA) to form a cement. PAA, tetracalcium phosphate (TetCP), and dicalcium phosphate (DCP) were reacted together and formed calcium ...

journal_title：Journal of dental research

authors： TenHuisen KS,Brown PW

更新日期：1994-03-01 00:00:00

abstract：:Due, in part, to the unique structure of the tooth, dental pain is initiated via distinct mechanisms. Here we review recent advances in our understanding of inflammatory tooth pain and discuss 3 hypotheses proposed to explain dentinal hypersensitivity: The first hypothesis, supported by functional expression of temper...

journal_title：Journal of dental research

authors： Chung G,Jung SJ,Oh SB

更新日期：2013-11-01 00:00:00

abstract：:Moderate elevation of serum C-reactive protein (CRP) is a risk factor for cardiovascular disease among apparently healthy individuals, although factors that create this inflammatory response in the absence of systemic illness have not been clarified. This study aimed to: (1) evaluate associations among periodontal dis...

journal_title：Journal of dental research

authors： Slade GD,Offenbacher S,Beck JD,Heiss G,Pankow JS

更新日期：2000-01-01 00:00:00

abstract：:MMP-20 (enamelysin), the matrix metalloproteinase family member discovered in the enamel organ, has also been detected in odontoblasts during dentin formation. We studied the presence and localization of MMP-20 in mature human teeth in health and disease. In immunohistochemistry, MMP-20-positive staining was observed ...

journal_title：Journal of dental research

authors： Sulkala M,Larmas M,Sorsa T,Salo T,Tjäderhane L

更新日期：2002-09-01 00:00:00

abstract：:Clinical evidence is lacking regarding the influence of the amount of residual coronal dentin and of post placement on the failure risk of endodontically compromised teeth. The aim of this prospective clinical trial was to assess whether these factors significantly affect the two-year survival of restored pulpless pre...

journal_title：Journal of dental research

authors： Ferrari M,Cagidiaco MC,Grandini S,De Sanctis M,Goracci C

更新日期：2007-08-01 00:00:00

abstract：:The present study was conducted to investigate the role of proteolysis by matrix metalloproteinase 20 (MMP20) in regulating the initial formation of the enamel mineral structure during the secretory stage of amelogenesis, utilizing Mmp20-null mice that lack this essential protease. Ultrathin sagittal sections of maxil...

journal_title：Journal of dental research

authors： Yamazaki H,Tran B,Beniash E,Kwak SY,Margolis HC

更新日期：2019-04-01 00:00:00

abstract：:Patients suffering from temporomandibular dysfunction exhibit clinical findings such as fatigue, painful muscles, and muscles that are tender to palpation, not only in the temporomandibular area, but also in the neck/shoulder region. The mechanisms behind this are not known, although previous studies of similar spread...

journal_title：Journal of dental research

authors： Hellström F,Thunberg J,Bergenheim M,Sjölander P,Pedersen J,Johansson H

更新日期：2000-10-01 00:00:00

abstract：:The balance between bone resorption and bone formation is vital for maintenance and regeneration of alveolar bone and supporting structures around teeth and dental implants. Tissue regeneration in the oral cavity is regulated by multiple cell types, signaling mechanisms, and matrix interactions. A goal for periodontal...

journal_title：Journal of dental research

authors： Larsson L,Decker AM,Nibali L,Pilipchuk SP,Berglundh T,Giannobile WV

更新日期：2016-03-01 00:00:00

abstract：:The biocompatibility of two implant materials, vitallium and poly-methyl methacrylate (PMMA), was evaluated in an animal model in which bone formation and resorption are independent of each other. Neither material accelerated resorption, but formation was inhibited 12% by vitallium and 38% by PMMA. When three PMMA pre...

journal_title：Journal of dental research

authors： Garcia DA,Sullivan TM,O'Neill DM

更新日期：1981-01-01 00:00:00

abstract：:The discoidin domain receptors, DDR1 and DDR2, are nonintegrin collagen receptors and tyrosine kinases. DDRs regulate cell functions, and their extracellular domains affect collagen fibrillogenesis and mineralization. Based on the collagenous nature of dentoalveolar tissues, we hypothesized that DDR1 plays an importan...

journal_title：Journal of dental research

authors： Chavez MB,Kolli TN,Tan MH,Zachariadou C,Wang C,Embree MC,Lira Dos Santos EJ,Nociti FH Jr,Wang Y,Tatakis DN,Agarwal G,Foster BL

更新日期：2019-12-01 00:00:00

abstract：:Teeth to be extracted for orthodontic reasons were filled in vivo with regular and fine-cut silver amalgams containing 1% and 5% SnF2. The teeth were extracted after 15 or 30 d, and the in vivo fluoride release and uptake by the dental tissues were studied using an electron microprobe analysis technique. The obtained ...

journal_title：Journal of dental research

authors： Souganidis DJ,Athanassouli TM,Papastathopoulos DS

更新日期：1981-02-01 00:00:00

abstract：:Defined sets of transcriptional factors can reprogram human somatic cells to induced pluripotent stem (iPS) cells. However, many types of human cells are not easily accessible to minimally invasive procedures. Here we evaluated dental pulp cells (DPCs) as an optimal source of iPS cells, since they are easily obtained ...

journal_title：Journal of dental research

authors： Tamaoki N,Takahashi K,Tanaka T,Ichisaka T,Aoki H,Takeda-Kawaguchi T,Iida K,Kunisada T,Shibata T,Yamanaka S,Tezuka K

更新日期：2010-08-01 00:00:00

abstract：:Since Thewlis found the "two fiber axes" patterns on x-ray diffractograms of human enamel in 1934, many investigators have studied this problem. However, a definite answer has not yet been obtained. The present detailed x-ray diffraction study showed that the "two fiber axes" patterns in human enamel were caused by re...

journal_title：Journal of dental research

authors： Hirota F

更新日期：1986-07-01 00:00:00

abstract：:The treatment of periodontitis/peri-implantitis involves the reduction/eradication of periopathogens. After therapy, beneficial and pathogenic species recolonize the subgingival area. The dynamics of recolonization and especially the role of the supragingival environment in this process are still not well-understood. ...

journal_title：Journal of dental research

authors： Quirynen M,Vogels R,Pauwels M,Haffajee AD,Socransky SS,Uzel NG,van Steenberghe D

更新日期：2005-04-01 00:00:00

abstract：:A three-month study of the chemistry of the water erosion of two forms of ASPA cement has been made. The effect of varying cement consistency and cure time was investigated. The results are discussed in terms of the known chemistry and structure of the cement. The erosion behavior is compared to that of silicate, sili...

journal_title：Journal of dental research

authors： Crisp S,Lewis BG,Wilson AD

更新日期：1976-11-01 00:00:00

abstract：:This randomized controlled trial aimed to evaluate the duration and outcome quality of orthodontic treatment with a customized fixed appliance system versus a noncustomized system. Patients ( n = 180) were randomized and received orthodontic treatment with the Insignia customized orthodontic system or the Damon Q nonc...

journal_title：Journal of dental research

authors： Penning EW,Peerlings RHJ,Govers JDM,Rischen RJ,Zinad K,Bronkhorst EM,Breuning KH,Kuijpers-Jagtman AM

更新日期：2017-12-01 00:00:00

abstract：:The fatigue crack growth resistance of dentin was characterized as a function of depth from the dentino-enamel junction. Compact tension (CT) specimens were prepared from the crowns of third molars in the deep, middle, and peripheral dentin. The microstructure was quantified in terms of the average tubule dimensions a...

journal_title：Journal of dental research

authors： Ivancik J,Neerchal NK,Romberg E,Arola D

更新日期：2011-08-01 00:00:00

abstract：:We placed an MOD preparation in each of 12 permanent molars, then restored each tooth with a posterior composite resin by means of six different application techniques (I-polymerization as one complete unit; II--polymerization as one complete unit with glass inserts; III--polymerization in gingivo-occlusal increments;...

journal_title：Journal of dental research

authors： Donly KJ,Wild TW,Bowen RL,Jensen ME

更新日期：1989-08-01 00:00:00

abstract：:Degradation of dentin matrix components within caries dentin has been correlated with the activity of host-derived proteases, such as matrix metalloproteases (MMPs) and cysteine cathepsins (CTs). Since this relationship has not been fully established, we hypothesized that the abundance of MMPs and CTs in caries-affect...

journal_title：Journal of dental research

authors： Vidal CM,Tjäderhane L,Scaffa PM,Tersariol IL,Pashley D,Nader HB,Nascimento FD,Carrilho MR

更新日期：2014-03-01 00:00:00

abstract：:Dental plaque collected from the label aspect of the anterior dentition of children harbored Neisseria that synthesized an extracellular iodophilic polysaccharide (EIP) from sucrose. Gas chromatograms of fully-acetylated EIP derivatives indicated that glucose (97%) and galactose (3%) were the only monosaccharide const...

journal_title：Journal of dental research

authors： Ruby JD,Shirey RE,Gerencser VF,Stelzig DA

更新日期：1982-05-01 00:00:00

abstract：:The purpose of this study was to investigate the genotoxic effects of chronic fluoride exposure on mammalian cells in vivo by use of the mouse bone-marrow micronucleus test and the sperm morphology methodology. Mice of genotype B6C3F1 were obtained at weaning and maintained on a low-fluoride diet (less than 0.2 ppm F)...

journal_title：Journal of dental research

authors： Dunipace AJ,Zhang W,Noblitt TW,Li Y,Stookey GK

更新日期：1989-11-01 00:00:00

abstract：:Acculturation is a complex phenomenon that can serve as a proxy for cultural norms and behaviors affecting care-seeking, prevention behaviors, and, ultimately, health outcomes. The purpose of this study was to assess the effect of acculturation on the oral health of Haitian immigrants in New York City. We hypothesized...

journal_title：Journal of dental research

authors： Cruz GD,Shore R,Le Geros RZ,Tavares M

更新日期：2004-02-01 00:00:00

abstract：:The field of dental materials has undergone more of a revolution than an evolution over the past 100 y. The development of new products, especially in the past half century, has occurred at a staggering pace, and their introduction to the market has been equally impressive. The movement has mostly come in the area of ...

journal_title：Journal of dental research

authors： Bayne SC,Ferracane JL,Marshall GW,Marshall SJ,van Noort R

更新日期：2019-03-01 00:00:00

abstract：:The kinetics of growth of calcium phosphates on synthetic hydroxyapatite (HAP), human enamel, whole dentin, and human calculus has been studied at 37 C at pH values from 4.97 to 5.10 held constant by the pH-stat addition of base. Following an initial induction period, dicalcium phosphate dihydrate (DCPD) crystallizati...

journal_title：Journal of dental research

authors： Barone JP,Nancollas GH

更新日期：1978-01-01 00:00:00