Abstract:
:Dental plaque collected from the label aspect of the anterior dentition of children harbored Neisseria that synthesized an extracellular iodophilic polysaccharide (EIP) from sucrose. Gas chromatograms of fully-acetylated EIP derivatives indicated that glucose (97%) and galactose (3%) were the only monosaccharide constituents present. The characterization of the partially-methylated alditol acetate (PMAA) derivatives of EIP indicated that it was primarily a linear 1,4 glucan (75.5%), with some 1,6 glucan (8.4%). The relative linearity of EIP (96.6%) as compared to that of amylose and glycogen was confirmed by spectrophotometric absorption studies.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Ruby JD,Shirey RE,Gerencser VF,Stelzig DAdoi
10.1177/00220345820610050101subject
Has Abstractpub_date
1982-05-01 00:00:00pages
627-31issue
5eissn
0022-0345issn
1544-0591journal_volume
61pub_type
杂志文章abstract::Molecular studies indicate that epigenetic events are important in determining how the internal enamel epithelium folds during odontogenesis. Since this process of folding leads to the subsequent arrangement of cusps on molar teeth, we hypothesized that intercuspal distances of human molar teeth would display greater ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200505
更新日期:2003-05-01 00:00:00
abstract::Dimensional alterations of the facial bone wall following tooth extractions in the esthetic zone have a profound effect on treatment outcomes. This prospective study in 39 patients is the first to investigate three-dimensional (3D) alterations of facial bone in the esthetic zone during the initial 8 wks following flap...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/0022034513506713
更新日期:2013-12-01 00:00:00
abstract::Growing evidence suggests that individual genetic susceptibility may influence the host's response to infections. The aim of this project was to study whether gene polymorphisms of inflammatory markers are associated with the presence of viable periodontopathogenic bacteria. We extracted genomic DNA from 45 young adul...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708600505
更新日期:2007-05-01 00:00:00
abstract::The cariostatic effect of resin-modified glass ionomer (RMGI) on secondary root caries is well-documented. However, this beneficial effect may be dependent upon the mode of cavity surface treatment. To investigate this relationship, we studied 4 cavity surface treatments prior to the placement of RMGI: no treatment (N...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200214
更新日期:2003-02-01 00:00:00
abstract::Patients with cleft lip/palate (CLP) have been reported, in some studies, to exhibit an increased prevalence of caries, although the underlying cause for this increase is unknown. In genetically defined mouse models, studies of postnatal sequelae associated with CLP have been hampered by neonatal lethality. Using a co...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516679376
更新日期:2017-03-01 00:00:00
abstract::In the past two decades, accumulated evidence has clearly demonstrated the inhibitory effects of laser irradiation on enamel demineralization, but the exact mechanisms of these effects remain unclear. The purpose of this study was to investigate the effects of low-energy CO2 laser irradiation on demineralization of bo...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790091401
更新日期:2000-09-01 00:00:00
abstract::Using glycoproteins and milk oligosaccharides as substrate acceptors, we demonstrated at least two fucosyltransferases in human parotid saliva. One enzyme transferred L-fucose from GDP-fucose to the C-3 position of N-acetylglucosamine or glucose residue of oligosaccharide chains, and the other transferred to the C-4 p...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620070701
更新日期:1983-07-01 00:00:00
abstract::Dietary components rich in polyphenols-for example, tea and red wine-are thought to cause tooth staining. In the present study, hydroxyapatite was used as a model of enamel for study of the influence of salivary proteins on the binding of different polyphenols to hydroxyapatite in vitro. Neither salivary protein pelli...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910508400113
更新日期:2005-01-01 00:00:00
abstract::A water-soluble lipopolysaccharide from Salmonella enteritidis and a phenol-soluble lipopolysaccharide from Leptotrichia buccalis were applied topically to the healthy marginal gingivae of beagle dogs. Saline was applied to contralateral areas as an internal control. Increases in vascular permeability were monitored b...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650020301
更新日期:1986-02-01 00:00:00
abstract::The role of Streptococcus mutans in the initiation of dental caries has been recognized and attributed, at least in part, to its ability to colonize the tooth surface. Therefore, factors which prevent S. mutans attachment to hydroxyapatite (HA) are of considerable interest for the prophylaxis of this infectious diseas...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760020701
更新日期:1997-02-01 00:00:00
abstract::Bone and dentin share similar biochemical compositions and physiological properties. Dentin, a major tooth component, is formed by odontoblasts; in contrast, bone is produced by osteoblasts. Osterix (Osx), a zinc finger-containing transcription factor, has been identified as an essential regulator of osteoblast differ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514565647
更新日期:2015-03-01 00:00:00
abstract::Dental enamel formation is a remarkable example of a biomineralization process. The exact mechanisms involved in this process remain partly obscure. Some of the genes encoding specific enamel proteins have been indicated as candidate genes for amelogenesis imperfecta. Mutational analyses within studied families have s...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/154405910508401206
更新日期:2005-12-01 00:00:00
abstract::The spatial relationship of the mandibular condyle to the temporal component of the TMJ is determined quantitatively from lateral tomograms using a new method of measuring specific areas of the joint space. Condyle position along the posteroanterior axis of the joint is expressed as a ratio of the posterior joint spac...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600010701
更新日期:1981-01-01 00:00:00
abstract::Chondroitin sulfate is up-regulated in granulation tissue during wound healing. To investigate the role of chondroitin sulfate in the wound-healing process after surgical repair of cleft palate, we isolated and cultured rabbit palatal fibroblasts. Treatment with chondroitin-6-sulfate resulted in a dose-dependent incre...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910408301111
更新日期:2004-11-01 00:00:00
abstract::Symphyseal secondary cartilage is important for mandibular development, but the molecular mechanisms underlying its formation remain largely unknown. Here we asked whether Indian hedgehog (Ihh) regulates symphyseal cartilage development and growth. By embryonic days 16.5 to 18.5, Sox9-expressing chondrocytes formed wi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510397836
更新日期:2011-05-01 00:00:00
abstract::Bisphosphonates are a class of agents used to treat osteoporosis and malignant bone metastases. The efficacy of these agents in treating and preventing the significant skeletal complications associated with these conditions has had a major positive impact for patients and is responsible for their widespread use in med...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/154405910708601101
更新日期:2007-11-01 00:00:00
abstract::Priming with tumor antigens is one of the most important strategies in cancer immunotherapy. To enhance tumor antigenicity, OK-432, a streptococcal preparation, was coupled to squamous cell carcinoma (KLN-205) by means of a 0.2% glutaraldehyde method. The purpose of this study was to investigate whether OK-432-conjuga...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200813
更新日期:2003-08-01 00:00:00
abstract::A simple in vitro method has been described for quantitatively measuring the rate at which isotopically labeled substances permeate through dentin in occlusal cavity preparations. The presence or absence of pulp tissue had only a minor effect on the kinetics of permeation. As the dentin was made thinner there was a re...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560011601
更新日期:1977-01-01 00:00:00
abstract::The treatment of periodontitis/peri-implantitis involves the reduction/eradication of periopathogens. After therapy, beneficial and pathogenic species recolonize the subgingival area. The dynamics of recolonization and especially the role of the supragingival environment in this process are still not well-understood. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910508400409
更新日期:2005-04-01 00:00:00
abstract::The effect of combined administration of chlorhexidine and fluoride in the drinking water of hamsters on plaque and caries prevention was studied. Plaque indices of the hamsters receiving chlorhexidine either alone or simultaneously with fluoride were significantly lower than those of the control and fluoride only tre...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560111401
更新日期:1977-11-01 00:00:00
abstract::Although it has been shown that patients are more satisfied with prostheses supported by implants than with conventional dentures, there have been few direct comparisons of the various designs of implant-supported prostheses. This within-subject crossover clinical trial was designed to compare two forms of removable p...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/00220345970760100901
更新日期:1997-10-01 00:00:00
abstract::This study's objective was to identify, in a statistically valid and efficient manner, the risk factors associated with dental implant failure. We hypothesize that factors exist which can be modified by clinicians to enhance outcome. A retrospective cohort study design was used. Cohort members had >or= one implant pla...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910208100814
更新日期:2002-08-01 00:00:00
abstract::Chemotherapeutics are presently considered for use in caries-preventive programs. The laboratory and in vivo testing of these agents, to some extent, parallels the methodology developed for the evaluation of fluoride products. However, fluoride is primarily effective by interfering with the de- and remineralization ba...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345940730031601
更新日期:1994-03-01 00:00:00
abstract::Improved mechanical properties of resin composites have been reported to be a consequence of the addition of aldehyde to the resins. The objective of the present study was to examine whether this improvement could be attributed to an increased degree of conversion of double bonds. For this purpose, propanal was added ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345940730101101
更新日期:1994-10-01 00:00:00
abstract::Morphogenesis (germ-tube formation) in Candida albicans was induced gratuitously by N-acetylhexosamine derivatives (N-acetyl-glucosamine covalently linked to agarose, N-acetylmannosamine, hyaluronic acid, colloidal chitin, and mucin). These compounds were not taken up by the yeast cells and did not support growth. 2-D...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630031501
更新日期:1984-03-01 00:00:00
abstract::Streptococcus mutans strain JH1005 is a mutant that produces levels of bacteriocin activity three-fold-elevated than those produced by its parent, JH1001. A single infection regimen with JH1005 was found to result in persistent colonization of the teeth of all three adult subjects tested. This is a significant improve...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660060101
更新日期:1987-06-01 00:00:00
abstract::During the polymerization of multifunctional monomers for dental restorations, typical final double-bond conversions range from 55 to 75%. The low conversion results in a large amount of extractable monomer, reduced adhesion to the filler, and the potential for increased swelling. In this work, the ability to increase...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750081301
更新日期:1996-08-01 00:00:00
abstract::Damage to the dentin matrix investigates the proliferation and mobilization of dental progenitor cells to the injury site, the mechanisms of which are not defined. EphB receptors and ephrin-B ligands expressed within the perivascular niche of dental pulp have been implicated following tooth injury. We propose that ele...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509342363
更新日期:2009-09-01 00:00:00
abstract::Relative glycogen synthetic abilities of resting cells of fresh clinical isolates of Actinomyces viscosus and Actinomyces naeslundii originating from dental plaque samples over root surface caries lesions and non-carious sites were studied under anaerobic conditions at a constant pH of 7.0, with U-(14C)-glucose used a...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650060701
更新日期:1986-06-01 00:00:00
abstract::Despite the recognized link between aging and cancer, most preclinical studies in experimental tumor models are conducted with 6- to 8-wk-old rodents. The goal of the present study was to examine the impact of age on tumor incidence, growth, and microenvironmental characteristics in mouse models of head and neck squam...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034518775736
更新日期:2018-10-01 00:00:00