Chlorhexide and fluoride in prevention of plaque and caries in hamsters.

Abstract:

:The effect of combined administration of chlorhexidine and fluoride in the drinking water of hamsters on plaque and caries prevention was studied. Plaque indices of the hamsters receiving chlorhexidine either alone or simultaneously with fluoride were significantly lower than those of the control and fluoride only treated hamsters. The type of plaque indices used in this investigation was area scores. The necessity of quantitatively assessing plaque by several parameters was emphasized. The degrees of caries of the experimental groups were significantly lower than of the control group during the cariogenic diet regime. The anticariogenic effect of chlorhexidine and fluoride at low concentrations each provided simultaneously with a cariogenic diet, was confirmed. The differences in caries rate between the experimental groups were not significant. No additive effect on the cariostatic action of chlorhexidine and fluoride was observed when both reagents were applied simultaneously due probably to the low F concentration in the drinking water. The results did not show a direct quantitative relationship between plaque and caries.

journal_name

J Dent Res

authors

Brayer L,Gedalia I,Gover A

doi

10.1177/00220345770560111401

subject

Has Abstract

pub_date

1977-11-01 00:00:00

pages

1365-8

issue

11

eissn

0022-0345

issn

1544-0591

journal_volume

56

pub_type

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