Axon reflex vasodilatation in cat dental pulp elicited by noxious stimulation of the gingiva.

Abstract:

:Antidromic stimulation of sensory nerves has been shown to increase blood flow in the tissue they innervate. This study was designed to determine if antidromic vasomotor responses occur in feline dental pulp and if they are mediated by branched axons supplying both tooth pulp and gingiva. Dynamic changes in pulpal blood flow (PBF) elicited by electrical stimulation, pinching, heating, and capsaicin application to the gingivae were investigated in cat mandibular canine teeth by means of Laser Doppler Velocimetry. All inferior alveolar nerve bundles and the cervical sympathetic trunk had been previously sectioned to avoid the occurrence of brainstem reflexes, e.g., somato-autonomic vasomotor reflexes. Increases in PBF were observed in seven out of 12 cats when a restricted gingival area adjacent to the canine teeth was stimulated as described, but the increases were abolished after the sensitive gingival area was painted with lidocaine jelly, a surface anesthetic. These vasodilator responses, remarkably reduced following repeated application of 30 mM of capsaicin, are considered to be induced via antidromic activation of capsaicin-sensitive nociceptive nerve fibers, presumably by axon reflex mechanisms, suggesting that nerve terminals supplying the gingiva originate from parent axons which have collaterals that innervate the canine tooth pulp.

journal_name

J Dent Res

authors

Sasano T,Kuriwada S,Shoji N,Sanjo D,Izumi H,Karita K

doi

10.1177/00220345940730120201

subject

Has Abstract

pub_date

1994-12-01 00:00:00

pages

1797-802

issue

12

eissn

0022-0345

issn

1544-0591

journal_volume

73

pub_type

杂志文章
  • Orthodontic force stimulates eNOS and iNOS in rat osteocytes.

    abstract::Mechanosensitive osteocytes are essential for bone remodeling. Nitric oxide, an important regulator of bone remodeling, is produced by osteocytes through the activity of constitutive endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). We hypothesized that these enzymes regulate the tiss...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034508330861

    authors: Tan SD,Xie R,Klein-Nulend J,van Rheden RE,Bronckers AL,Kuijpers-Jagtman AM,Von den Hoff JW,Maltha JC

    更新日期:2009-03-01 00:00:00

  • Global Economic Impact of Dental Diseases.

    abstract::Reporting the economic burden of oral diseases is important to evaluate the societal relevance of preventing and addressing oral diseases. In addition to treatment costs, there are indirect costs to consider, mainly in terms of productivity losses due to absenteeism from work. The purpose of the present study was to e...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034515602879

    authors: Listl S,Galloway J,Mossey PA,Marcenes W

    更新日期:2015-10-01 00:00:00

  • Enamel silicon and fluoride relationships demonstrating a surface silicon effect that facilitates fluoride uptake.

    abstract::This study indicated that a clear relationship exists between silicon and fluoride. We have also demonstrated a probable surface enamel silicon effect that increases fluoride uptake. The complex set of relationships described in the surface chemistry of calcium, tin, and zirconium with fluoride, hydroxide, phosphate, ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345760550050601

    authors: Levy JS,Koritzer RT

    更新日期:1976-09-01 00:00:00

  • Dental fluorosis in the primary and the permanent dentition in fluoridated areas with consumption of either powdered milk or natural cow's milk.

    abstract::The aim of the present study was to describe the patterns of dental fluorosis in the primary and the permanent dentition of children born and reared in two different fluoridated areas, one in which powdered milk suspended in tap water was commonly used (Narssaq, Greenland: 1.1 ppm fluoride in the water) and one in whi...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345880670050501

    authors: Larsen MJ,Senderovitz F,Kirkegaard E,Poulsen S,Fejerskov O

    更新日期:1988-05-01 00:00:00

  • Evaluation of analytical methods for fluorine in biological and related materials.

    abstract::During the past two decades, some major pitfalls in fluorine analysis have been recognized and overcome. Therefore, it is important that facts be separated from fallacies in published literature on levels and forms of fluorine (ionic, bound, covalent, etc.) in biological materials, in order that correct perceptions of...

    journal_title:Journal of dental research

    pub_type: 杂志文章,评审

    doi:10.1177/00220345900690S105

    authors: Venkateswarlu P

    更新日期:1990-02-01 00:00:00

  • Tensile properties of resin-infiltrated demineralized human dentin.

    abstract::The ability of adhesive resins to restore the physical properties of demineralized dentin has not been well-documented. The unfilled resins that are used for adhesion have relatively low moduli of elasticity and limited ability to increase dentin stiffness, although they may increase the ultimate tensile strength of d...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345950740041001

    authors: Sano H,Takatsu T,Ciucchi B,Russell CM,Pashley DH

    更新日期:1995-04-01 00:00:00

  • Postnatal Identification of Zika Virus Peptides from Saliva.

    abstract::We explored the potential to diagnose Zika virus (ZIKV) infection by analyzing peptides in saliva during a convalescent phase of infection, long after resolution of acute disease. A 25-y-old woman clinically diagnosed with Zika fever in the first trimester was enrolled with her dizygotic twins for a 3-mo postnatal sam...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034517723325

    authors: Zuanazzi D,Arts EJ,Jorge PK,Mulyar Y,Gibson R,Xiao Y,Bringel Dos Santos M,Machado MAAM,Siqueira WL

    更新日期:2017-09-01 00:00:00

  • Induced hypoxia in rat pulp and periapex demonstrated by 3H-misonidazole retention.

    abstract::Cellular hypoxia may be a useful indication of tissue distress in the dental pulp that could be used to investigate the early stages of pulpal responses. Tritiated misonidazole (3H-MISO) is a marker which preferentially labels cells with decreased oxygen tension (hypoxia). The experiments reported here were carried ou...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345960750100801

    authors: Baumgardner KR,Walton RE,Osborne JW,Born JL

    更新日期:1996-10-01 00:00:00

  • Bayesian analysis of clustered interval-censored data.

    abstract::The recording of multiple interval-censored failure times is common in dental research. Modeling multilevel data has been a difficult task. This paper aims to use the Bayesian approach to analyze a set of multilevel clustered interval-censored data from a clinical study to investigate the effectiveness of silver diami...

    journal_title:Journal of dental research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/154405910508400907

    authors: Wong MC,Lam KF,Lo EC

    更新日期:2005-09-01 00:00:00

  • Analysis of vitamin D and Fcgamma receptor polymorphisms in Japanese patients with generalized early-onset periodontitis.

    abstract::Early-onset periodontitis (EOP) is considered to have a genetic basis which has not been clearly defined. Genetic polymorphisms of the vitamin D receptor (VDR-B-b) and the immunoglobulin-Fc-gamma receptor IIIb (FcgammaRIIIb-NA1-NA2) are associated with bone metabolism and infectious diseases, respectively. The purpose...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345010800120501

    authors: Yoshihara A,Sugita N,Yamamoto K,Kobayashi T,Miyazaki H,Yoshi H

    更新日期:2001-12-01 00:00:00

  • Purification of lingual amylase from serous glands of rat tongue and characterization of rat lingual amylase and lingual lipase.

    abstract::Lingual amylase and lingual lipase, two digestive enzymes that are secreted from lingual serous glands (von Ebner's), were simultaneously purified from rat lingual serous glands with hydrophobic chromatography used as the final step. This method, previously developed for the purification of lingual lipase, includes ho...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345890680020801

    authors: Field RB,Spielman AI,Hand AR

    更新日期:1989-02-01 00:00:00

  • The effect of high sugar intake on the development of periradicular lesions in rats with type 2 diabetes.

    abstract::Diabetes mellitus is associated with depression of natural defenses against infection and increases the risk of periodontal disease. However, the effects of diabetes on periradicular tissue, which differs structurally from periodontal tissue, are not known. In this study, we evaluated the effects of type 2 diabetes on...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910308200416

    authors: Iwama A,Nishigaki N,Nakamura K,Imaizumi I,Shibata N,Yamasaki M,Nakamura H,Kameyama Y,Kapila Y

    更新日期:2003-04-01 00:00:00

  • Finite element stress analysis of a class I amalgam restoration subjected to setting and thermal expansion.

    abstract::Stress analyses are presented for a second mandibular premolar with a class 1 amalgam restoration. The effects of amalgam setting and thermal expansions are examined. An axisymmetric representation of the structure is used and the analyses are carried out by the finite element method. Lined and unlined restorations ar...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345780570051101

    authors: Wright KW,Yettram AL

    更新日期:1978-05-01 00:00:00

  • Adherence controlling elements in ceramic-metal systems. I. Precious alloys.

    abstract::Elemental analysis of two precious alloyceramic systems revealed the accumulation of Sn atoms within the interaction zone of couples subjected to a range of metal oxidation time; and varying total firing times. The source of Sn atoms which accumulated within the interaction zone was the opaque porcelain layer which co...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345770560090301

    authors: Anusavice KJ,Horner JA,Fairhurst CW

    更新日期:1977-09-01 00:00:00

  • The extent of the odontoblast process in human dentin.

    abstract::Impacted human third molar teeth were examined, both with the light and electron microscope, to determine the extent of the odontoblast process. The odontoblast process was found to be limited to the inner third of coronal dentin and inner half of mid-root dentin. ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/002203457905800412011

    authors: Thomas HF

    更新日期:1979-11-01 00:00:00

  • Numbers of natural teeth, diet, and nutritional status in US adults.

    abstract::Evidence that dental status affects diet is equivocal. The hypothesis of this study was that diet was affected by dental status. The objective was to assess the relationship between numbers of teeth and diet and nutritional status in US adult civilians without prostheses. We examined 6985 NHANES (1988-1994) participan...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910708601206

    authors: Nowjack-Raymer RE,Sheiham A

    更新日期:2007-12-01 00:00:00

  • A rheological study of the role of additives on the setting of glass-ionomer cements.

    abstract::The effects of various additives on the setting of the glass-ionomer cement system was studied by means of cone and plate viscometry. The action of (+)-tartaric acid, the most important additive, on the setting reaction depended on its concentration. Low concentrations accelerated the development of viscosity of the c...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345880670120101

    authors: Hill RG,Wilson AD

    更新日期:1988-12-01 00:00:00

  • Resin elasticity and the strengthening of all-ceramic restorations.

    abstract::Resin luting of all-ceramic restorations results in increased performance; however, the strengthening mechanism and the role of the mechanical properties of the resin are not fully understood. The hypothesis tested is that ceramic strength enhancement is dependent on the elastic modulus of the resin. Three-point flexu...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910708600606

    authors: Addison O,Marquis PM,Fleming GJ

    更新日期:2007-06-01 00:00:00

  • The effect of dental amalgams on mercury levels in expired air.

    abstract::The expired air of a group of 48 persons, 40 with and eight without dental amalgam restorations, was analyzed for its mercury content before and after chewing. Expired air samples were collected in polyethylene bags, and a known quantity of each was pumped into the mercury detector for measurement. The results showed ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345810600090601

    authors: Svare CW,Peterson LC,Reinhardt JW,Boyer DB,Frank CW,Gay DD,Cox RD

    更新日期:1981-09-01 00:00:00

  • The effects of etching, micro-abrasion, and bleaching on surface enamel.

    abstract::Conservative techniques for improving the appearance of discolored teeth have become popular in the past decade. These include: in-office bleaching with 30% hydrogen peroxide, which is applied on etched enamel with a gauze pad and then exposed to a bleaching light; home bleaching with a mild form of peroxide, such as ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345930720011001

    authors: Tong LS,Pang MK,Mok NY,King NM,Wei SH

    更新日期:1993-01-01 00:00:00

  • Antimalarial drugs and reduced incidence of dental plaque.

    abstract::Known antimalarial compunds from several chemical classes were tested for their ability to inhibit in vitro growth of microorganisms causing dental plaque and to prevent the development of plaque in a hamster model. Approximately a third of the compounds tested inhibited in vitro growth; however, none prevented develo...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345750540030901

    authors: Kinnamon KE,Eckermann EH,Tempel TR,Smith JH,Wolf CR

    更新日期:1975-05-01 00:00:00

  • Cathelicidin antimicrobial peptides are expressed in salivary glands and saliva.

    abstract::The expression of antimicrobial peptides at epithelial surfaces such as skin, lung, and intestine is thought to provide protection against infection. Cathelicidin antimicrobial peptides are essential for the protection of skin against invasive bacterial infection. To determine if cathelicidins are also present in the ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910208101210

    authors: Murakami M,Ohtake T,Dorschner RA,Gallo RL

    更新日期:2002-12-01 00:00:00

  • Distribution and excretion of TEGDMA in guinea pigs and mice.

    abstract::The monomer triethyleneglycoldimethacrylate (TEGDMA) is used as a diluent in many resin-based dental materials. It was previously shown in vitro that TEGDMA was released into the adjacent biophase from such materials during the first days after placement. In this study, the uptake, distribution, and excretion of 14C-T...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345010800050501

    authors: Reichl FX,Durner J,Hickel R,Kunzelmann KH,Jewett A,Wang MY,Spahl W,Kreppel H,Moes GW,Kehe K,Walther U,Forth W,Hume WR

    更新日期:2001-05-01 00:00:00

  • A new approach to the study of tooth wear.

    abstract::Human tooth wear occurs so slowly that traditionally it has needed months or years to be measurable. This study showed that microscopic changes in wear patterns on human teeth could be detected in a matter of days and could be used as indicators of rates of wear. Thus, daily or weekly changes in rates of wear can be d...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345910700030901

    authors: Teaford MF,Tylenda CA

    更新日期:1991-03-01 00:00:00

  • Functional characteristics of gingival and periodontal ligament fibroblasts.

    abstract::In periodontal surgery, healing after guided tissue regeneration (GTR) may be explained by differences in functional activities of gingival and periodontal ligament fibroblasts (GF and PDLF). Several studies in vitro have supported this hypothesis, but much remains to be defined. In the present work, gingival and peri...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345960750030601

    authors: Giannopoulou C,Cimasoni G

    更新日期:1996-03-01 00:00:00

  • The initial gap around large composite restorations in vitro: the effect of etching enamel walls.

    abstract::Composite resin restorations in cavities are generally associated with the development of a contraction gap during the first minutes after insertion. Enamel-Bond-Concise composite restoration were placed on both approximal sides of extracted pre-molars. The cervical walls of all cavities extended beyond the enamel-cem...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345840630051501

    authors: Brännström M,Torstenson B,Nordenvall KJ

    更新日期:1984-05-01 00:00:00

  • Clinical placement and performance of composite resin restorations.

    abstract::The most frequent complaints registered against composite restorations are stained margins and a rough surface. The stained margins have many causes such as (1) fracturing or crazing of enamel during preparation of the cavity, (2) using a composite having an excessive curing shrinkage, (3) manipulating too slowly, whi...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345790580052101

    authors: Rupp NW

    更新日期:1979-05-01 00:00:00

  • The measurement of the effect of toothbrushes on soft tissue abrasion.

    abstract::The effect of toothbrushes on soft tissue abrasion was measured using hamster cheek pouch tissue brushed mechanically for various intervals. The detection of protein removed during brushing was used as an index of tissue abrasion. The method was found to be sensitive in detecting the effects of brush load, number of s...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345770560070301

    authors: Alexander JF,Saffir AJ,Gold W

    更新日期:1977-07-01 00:00:00

  • Effects of ultrasound modes on mandibular osteodistraction.

    abstract::Previous studies have shown that therapeutic pulsed ultrasound (pulsed) has superior stimulatory effect on bone fracture healing compared with continuous ultrasound (continuous). Our predictive hypothesis was that pulsed ultrasound can produce better bone formation during mandibular osteodistraction than continuous ul...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910808701018

    authors: El-Bialy TH,Elgazzar RF,Megahed EE,Royston TJ

    更新日期:2008-10-01 00:00:00

  • Correlation of the hydrolysis of benzoyl-arginine naphthylamide (BANA) by plaque with clinical parameters and subgingival levels of spirochetes in periodontal patients.

    abstract::Recent studies have shown that the extent of hydrolysis by plaque of the trypsin substrate, N-benzoyl-DL-arginine-2-naphthylamide (BANA), correlates with the numbers and proportions of spirochetes in subgingival plaque samples, and appears to be an indicator of clinical disease. In this study, BANA hydrolysis by subgi...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345880670121201

    authors: Schmidt EF,Bretz WA,Hutchinson RA,Loesche WJ

    更新日期:1988-12-01 00:00:00