Abstract:
:The effect of toothbrushes on soft tissue abrasion was measured using hamster cheek pouch tissue brushed mechanically for various intervals. The detection of protein removed during brushing was used as an index of tissue abrasion. The method was found to be sensitive in detecting the effects of brush load, number of strokes applied, and the texture of the brush. The results further showed that the mechanical removal of sharp edges from bristle tips substantially reduced the level of soft tissue abrasion while a dentifrice polishing agent applied to the tissue with a brush did not increase the abrasive effect of the brush.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Alexander JF,Saffir AJ,Gold Wdoi
10.1177/00220345770560070301subject
Has Abstractpub_date
1977-07-01 00:00:00pages
722-7issue
7eissn
0022-0345issn
1544-0591journal_volume
56pub_type
杂志文章abstract::During periods of periodontal attachment loss, one of the most significant cellular changes is a decrease in the number of fibroblasts. We previously demonstrated that LPS induces apoptosis of fibroblastic cells in vivo, largely through TNF-alpha. We conducted in vivo experiments by subcutaneous inoculation of LPS in ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910408300903
更新日期:2004-09-01 00:00:00
abstract::Antigenic alterations to the dentin organic matrix may be detected by an immunohistochemical approach. We hypothesized that alterations in the antigenicity of type I collagen and proteoglycans occur in sclerotic dentin under caries lesions. Transverse sections were prepared from carious teeth in the sclerotic zone and...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500204
更新日期:2006-02-01 00:00:00
abstract::The amount of free water in 50 samples of air-dried enamel from permanent and deciduous teeth was measured by the Karl Fischer method. Samples included both contemporary and burial specimens. The mean values obtained showed that free water constituted about 1% of enamel mass. However, the range of individual values va...
journal_title:Journal of dental research
pub_type: 历史文章,杂志文章
doi:10.1177/00220345880670051701
更新日期:1988-05-01 00:00:00
abstract::Microducers and modified cephalometric roentgenogram techniques were used to study maximum biting forces and moments in an adult male. The force at the second molar was approximately 10% greater than that at the first molar. At the second molar, the moment of force was approximately 15% less than its value at the firs...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345750540010401
更新日期:1975-01-01 00:00:00
abstract::The sequelae of sustained, in vivo delivery of two important neurotransmitter substances, glutamate and thyrotropin-releasing hormone (TRH), upon craniofacial growth and development have previously not been investigated. Our purpose was to document and compare the relative effects of glutamate and TRH microspheres ste...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760080601
更新日期:1997-08-01 00:00:00
abstract::Insulin resistance is one of the critical pathogeneses of type 2 diabetes mellitus (T2DM). Elevated levels of plasma branched-chain amino acids (BCAAs) are associated with insulin resistance. Recent studies have demonstrated the role of Porphyromonas gingivalis in the development of insulin resistance. However, the me...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520911037
更新日期:2020-07-01 00:00:00
abstract::Loss of hybrid layer integrity compromises resin-dentin bond stability. Matrix metalloproteinases (MMPs) may be partially responsible for hybrid layer degradation. Since chlorhexidine inhibits MMPs, we hypothesized that chlorhexidine would decelerate the loss of resin-dentin bonds. Class I preparations in extracted th...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/154405910708600115
更新日期:2007-01-01 00:00:00
abstract::IL-18 is a pro-inflammatory cytokine that is important in the regulation of T-cells and is elevated in inflammatory disorders such as periodontal disease. Vasoactive intestinal peptide (VIP) modulates immune responses to the periodontal pathogen Porphyromonas gingivalis (Pg). Our objective was to investigate the effec...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708600915
更新日期:2007-09-01 00:00:00
abstract::The discovery and implementation of fluoride in the prevention of dental caries is often praised as one of the most important achievements in health care. In the early 20th century, it took 30 y to identify fluoride as the cause of enamel mottling but also of reduced caries prevalence in a population drinking water co...
journal_title:Journal of dental research
pub_type: 历史文章,杂志文章
doi:10.1177/0022034519831604
更新日期:2019-07-01 00:00:00
abstract::When measured once, psychological stress predicts development of painful temporomandibular disorder (TMD). However, a single measurement fails to characterize the dynamic nature of stress over time. Moreover, effects of stress on pain likely vary according to biological susceptibility. We hypothesized that temporal es...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515595043
更新日期:2015-09-01 00:00:00
abstract::Defects in the enamelin gene (ENAM) cause amelogenesis imperfecta (AI). Our objective was to identify the genetic etiology of enamel hypoplasia in a Caucasian proband. Our hypothesis was that ENAM was defective. The proband and his father have an AG insertion (g.13185_13186insAG; p.422FsX448) in ENAM previously identi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510365662
更新日期:2010-07-01 00:00:00
abstract::Adhesion of restorative and protective materials to dentin is an important requirement for operative and preventive dentistry. Wettability and roughness are dentin substrate conditions that are critical to establishing good adhesion. This study examined superficial and deep dentin for variations in water contact angle...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345990780091001
更新日期:1999-09-01 00:00:00
abstract::Adhesives cured under constrained conditions develop contraction stresses. We hypothesized that, with dentin as a bonding substrate, the stress would reach a maximum, followed by a continuous decline. Stress development was determined with a tensilometer for two total-etch systems and two systems with self-etching pri...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500808
更新日期:2006-08-01 00:00:00
abstract::Seven oral doses of demethylchlortetracycline were administered to monkeys that received serial injections of lead acetate to intravitally stain calcification sites. Bone growth was greatly inhibited, whereas dentin apposition was spared from the cumulative toxicity of demethylchlortetracycline. Cessation of bone grow...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::Inflammatory conditions as they occur during periodontal disease often result in decreased alveolar bone levels and a loss of connective tissue homeostasis. Here we have focused on the effect of microRNA-138 (miR-138) as a potential regulator of periodontal stem cells as they affect homeostasis during inflammatory con...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515613043
更新日期:2016-02-01 00:00:00
abstract::Periodontitis is a chronic inflammatory disease affecting oral tissues. The continuous, high production of cytokines by host cells triggered by periodontopathogens is thought to be responsible for the destruction of tooth-supporting tissues. Macrophages play a critical role in this host inflammatory response to period...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500306
更新日期:2006-03-01 00:00:00
abstract::Acute or chronic inflammation comprises a highly prevalent type of orofacial pain and is mediated by the generation of endogenous agonists that activate numerous receptors expressed on terminals of trigeminal (TG) nociceptive afferent neurons. One such studied receptor is transient receptor potential vanilloid subtype...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034516653751
更新日期:2016-09-01 00:00:00
abstract::The periodontium contains heterogeneous mesenchymal cell populations with various differentiation potentials. The capacity of these cells for tissue formation as well as the origin of their precursors are still not entirely defined. In this study, cells originating from different periodontal tissues were cultured in v...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345950740051201
更新日期:1995-05-01 00:00:00
abstract::This systematic review and meta-analysis assessed the efficacy of lasers in reducing dentin hypersensitivity (DH) as compared with placebo or no treatment. Seven electronic databases and a manual search resulted in 2,538 unique publications. After selection, 13 studies were included in the meta-analysis. A CONSORT-bas...
journal_title:Journal of dental research
pub_type: 杂志文章,meta分析,评审
doi:10.1177/0022034513487212
更新日期:2013-06-01 00:00:00
abstract::Teeth to be extracted for orthodontic reasons were filled in vivo with regular and fine-cut silver amalgams containing 1% and 5% SnF2. The teeth were extracted after 15 or 30 d, and the in vivo fluoride release and uptake by the dental tissues were studied using an electron microprobe analysis technique. The obtained ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600020101
更新日期:1981-02-01 00:00:00
abstract::The uptake patterns of 90Sr in developing rat molar enamel were studied in vivo and in vitro. Autoradiographic methods were used that preclude loss or translocation of tracers associated with water-soluble compounds in the sections. In eight-day-old rats injected with the tracer, 90Sr uptake in the enamel was signific...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590121301
更新日期:1980-12-01 00:00:00
abstract::The purpose of this investigation was to determine whether chlorhexidine combined with copper would exert a synergistic, growth-inhibitory effect against selected oral bacteria. Actinomyces viscosus, Actinomyces naeslundii, and Streptococcus mutans were all susceptible to chlorhexidine individually, with S. mutans dis...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720020901
更新日期:1993-02-01 00:00:00
abstract::Antimicrobial agents, delivered either by mouthrinse or toothpaste, can be used to maintain plaque at levels compatible with oral health by (a) reducing existing plaque, (b) preventing the formation of new plaque, (c) selectively inhibiting those particular bacteria that are associated with disease, and (d) inhibiting...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345920710071501
更新日期:1992-07-01 00:00:00
abstract::Dimensional alterations of the facial bone wall following tooth extractions in the esthetic zone have a profound effect on treatment outcomes. This prospective study in 39 patients is the first to investigate three-dimensional (3D) alterations of facial bone in the esthetic zone during the initial 8 wks following flap...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/0022034513506713
更新日期:2013-12-01 00:00:00
abstract::Priming with tumor antigens is one of the most important strategies in cancer immunotherapy. To enhance tumor antigenicity, OK-432, a streptococcal preparation, was coupled to squamous cell carcinoma (KLN-205) by means of a 0.2% glutaraldehyde method. The purpose of this study was to investigate whether OK-432-conjuga...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200813
更新日期:2003-08-01 00:00:00
abstract::Vitamin D, an anti-inflammatory mediator, has potential benefits for physical and oral health. Although it is produced endogenously, some individuals have a greater need for dietary and supplemental sources. This repeated-measures cross-sectional study assessed associations between total vitamin D intake and periodont...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513495239
更新日期:2013-08-01 00:00:00
abstract::Bacteria attach to teeth and oral mucosal surfaces in a surprisingly selective manner, and attachment appears to be the first step in the colonization process. Attachment is thought to involve lectin-like and/or hydrophobic ligands, called adhesins, often present in bacterial surface appendages which interact with rec...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630030401
更新日期:1984-03-01 00:00:00
abstract::Pain and discomfort are common problems for patients undergoing orthodontic treatment. We have demonstrated that cortical excitation propagation in the somatosensory and insular cortices (IC) induced by electrical stimulation of the periodontal ligament (PDL) is facilitated 1 d after experimental tooth movement (ETM)....
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520962465
更新日期:2020-10-08 00:00:00
abstract::We evaluated the histopathological response of the periodontal membrane to intentionally-replanted teeth carrying composite (experimental) and silver amalgam (control) restorations in the middle third of each root. The study revealed that the amalgam produced, in the periodontal tissues, an initial localized inflammat...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620011801
更新日期:1983-01-01 00:00:00
abstract::Deciduous teeth were collected from children who received professional prophylaxis with an acidulated phosphate-fluoride (APF) or placebo paste and were analyzed to determine fluoride uptake. Enamel fluoride level was increased by the APF paste approximately 300 ppm at a depth of 2.5 micrometers during the first month...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550064901
更新日期:1976-11-01 00:00:00