Effects of repeated oral doses of demethylchlortetracycline on bones and dentin of young rhesus monkeys.

Abstract:

:Seven oral doses of demethylchlortetracycline were administered to monkeys that received serial injections of lead acetate to intravitally stain calcification sites. Bone growth was greatly inhibited, whereas dentin apposition was spared from the cumulative toxicity of demethylchlortetracycline. Cessation of bone growth and its duration could be correlated with serum levels.

journal_name

J Dent Res

authors

Yen PK,Shaw JH

subject

Has Abstract

pub_date

1975-03-01 00:00:00

pages

358-64

issue

2

eissn

0022-0345

issn

1544-0591

journal_volume

54

pub_type

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