Abstract:
:Seven oral doses of demethylchlortetracycline were administered to monkeys that received serial injections of lead acetate to intravitally stain calcification sites. Bone growth was greatly inhibited, whereas dentin apposition was spared from the cumulative toxicity of demethylchlortetracycline. Cessation of bone growth and its duration could be correlated with serum levels.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Yen PK,Shaw JHsubject
Has Abstractpub_date
1975-03-01 00:00:00pages
358-64issue
2eissn
0022-0345issn
1544-0591journal_volume
54pub_type
杂志文章abstract::Dental pulp regeneration therapy for the pulpless tooth has attracted recent attention, and clinical trial studies are underway with the tissue engineering approach. However, there remain many concerns, including the extended period for regenerating the dental pulp. In addition, the use of scaffolds increases the risk...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034518772260
更新日期:2018-09-01 00:00:00
abstract::Enamel abraders used in two-body wear tests suffer the disadvantage that standardization is difficult or impossible to obtain. The aim of this study was to test whether steatite (a ceramic material with a Vickers Hardness similar to that of enamel) could be used as a satisfactory human enamel analogue. The friction an...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345940730091001
更新日期:1994-09-01 00:00:00
abstract::In this study, we first investigated the expressions of Jagged1, Notch2, the receptor activator of nuclear factor-kappa B ligand (RANKL), and interleukin (IL)-6 in areas of root resorption during experimental tooth movement in rats in vivo. We then assessed the effects of compression force (CF) with or without GSI (an...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514555364
更新日期:2015-01-01 00:00:00
abstract::Since 1935, various mechanisms have been suggested for the formation of subsurface lesions and, in particular, the surface layer covering enamel lesions. The relatively intact mineral-rich and porous surface layer is most likely caused by kinetic events. The suggested mineral-rich outer layer in sound enamel, the orga...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345860650010201
更新日期:1986-01-01 00:00:00
abstract::Dendritic cells, such as Langerhans cells (LC), in different ectodermal compartments may have different functional capabilities. The present study was undertaken to compare oral Langerhans cells (LC) with those of the epidermis in terms of their ability to co-stimulate T-cells in vitro. A Mixed Epithelial Cell Lymphoc...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345990780030701
更新日期:1999-03-01 00:00:00
abstract::It is claimed that dental fluorosis in both deciduous and permanent teeth is increasing in fluoridated and non-fluoridated communities. What is unclear is whether fluoride-induced enamel opacities in the deciduous dentition are associated with the subsequent appearance of enamel defects in the permanent dentition. The...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750040301
更新日期:1996-04-01 00:00:00
abstract::Breastfeeding is a powerful health-promoting behavior. A 2016 Lancet global collaboration to review the health implications of breastfeeding was among the first to consider oral health outcomes. While a role was suggested for breastfeeding in preventing malocclusion, caries was the only included disease condition unfa...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034517738925
更新日期:2018-03-01 00:00:00
abstract::Tritiated proline was administered to domestic cats during the development of their permanent dentition. The amount of residual radioactivity was determined autoradiographically at various times after cavity preparation in mature molars and premolars. Two wk after cavity preparation, the amount of radiolabel beneath t...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345820610090101
更新日期:1982-09-01 00:00:00
abstract::Impacted human third molar teeth were examined, both with the light and electron microscope, to determine the extent of the odontoblast process. The odontoblast process was found to be limited to the inner third of coronal dentin and inner half of mid-root dentin. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/002203457905800412011
更新日期:1979-11-01 00:00:00
abstract::The Wingless/integrase-1 (Wnt) family of protein ligands and their functional antagonists, secreted frizzled-related proteins (sFRPs), regulate various biological processes ranging from embryonic development to immunity and inflammation. Wnt5a and sFRP5 comprise a typical ligand/antagonist pair, and the former molecul...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516687248
更新日期:2017-05-01 00:00:00
abstract::To date, the precise etiology of molar-incisor hypomineralization (MIH) is uncertain. Vitamin D plays a key role in hard tissue formation. Therefore, this study aimed to analyze the relationship between serum 25-hydroxy-vitamin D (25(OH)D) status and dental health data obtained from 1,048 children in a 10-year follow-...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514561657
更新日期:2015-02-01 00:00:00
abstract::Excessive mechanical stress (MS) during hyperocclusion is known to result in disappearance of the alveolar hard line, enlargement of the periodontal ligament (PDL) space, and destruction of alveolar bone, leading to occlusal traumatism. We hypothesized that MS induces expression of osteoclastogenesis-associated chemok...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034511400742
更新日期:2011-06-01 00:00:00
abstract::Pieces of fresh rat incisor enamel were extracted with various buffer solutions and prepared for electron microscopy. I observed partial or complete removal of organic constituents, shrinkage of rods and interrods, separation of stippled material from the enamel, and partial decalcification. The results modify the con...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:1982-12-01 00:00:00
abstract::Dissolution of mercury from amalgams and some intermetallic compounds found in the amalgam structure, such as gamma 1, gamma 2, and beta 1, was examined during one week of aging in 0.9% NaCl solution at 37 degrees C. The amount of mercury released from gamma 1 (30.2 micrograms/cm2) was at least 13 times that released ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660010701
更新日期:1987-01-01 00:00:00
abstract::A/Jax mice were injected with 50 muCi of 3H cortisol and 10 mg of cortisone acetate on day 12 of gestation. At various intervals after injection, the maternal liver, placenta, yolk sac, and the fetal jaws were removed and analyzed by thin-layer chromatography in conjunction with oxidative combustion and liquid scintil...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345750540051101
更新日期:1975-09-01 00:00:00
abstract::When one uses composite resins, the curing contraction, the stiffness of the material, and the strength of the vulnerable dentinal bond are important factors in determining the marginal adaptation of the restoration. Calculations based on these intrinsic material properties have indicated that both bulk placement and ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670050901
更新日期:1988-05-01 00:00:00
abstract:UNLABELLED:Dental caries affects most adults worldwide; however, the risk factors for dental caries do not necessarily exert their effects uniformly across all tooth surfaces. Instead, the actions of some risk factors may be limited to a subset of teeth/surfaces. Therefore, we used hierarchical clustering on tooth surf...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034512463241
更新日期:2013-01-01 00:00:00
abstract::The human patched gene (PTCH) functions in both embryologic development and tumor suppression. PTCH mutations have been found in odontogenic keratocysts. However, the expression and localization of the protein product of the gene have not been determined in odontogenic tumors and cysts. We investigated 68 odontogenic ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0810757
更新日期:2002-11-01 00:00:00
abstract::The gingival microbiota in beagle dogs was investigated during a period of 42 days after the placement of continuous wire and arch bar splints. The splints were found to induce an increase in helicoidal-shaped micro-organisms and black-pigmented Bacteroides. Two different asaccharolytic Bacteroides types were isolated...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630110601
更新日期:1984-11-01 00:00:00
abstract::Mutations and common polymorphisms in interferon regulatory factor 6 ( IRF6) are associated with both syndromic and nonsyndromic forms of cleft lip/palate (CLP). To date, much of the focus on this transcription factor has been on identifying its direct targets and the gene regulatory network in which it operates. Nota...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034517723615
更新日期:2017-10-01 00:00:00
abstract::A major extracellular protein of cultured adult human gingival fibroblasts was shown to be fibronectin by indirect immunofluorescence, lactoperoxidase catalyzed iodination and metabolic radiolabeling. Fibronectin preparations from these cells possessed the biological properties of agglutination of sheep red blood cell...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590031301
更新日期:1980-03-01 00:00:00
abstract::Inorganic polyphosphate [Poly(P)] is especially prevalent in osteoblasts. We tested the hypothesis that Poly(P) stimulates osteoblastic differentiation and polyphosphate metabolism for bone formation. The osteoblast-like cell line, MC 3T3-E1, was cultured with Poly(P), and gene expression was evaluated by real-time re...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510363096
更新日期:2010-05-01 00:00:00
abstract::The tissue-implant interfaces of functional and non-functional endosseous dental implants were compared histologically for up to one year post-operatively. Nonmineralized connective tissue zones (a "fibrous capsule") existed in all functional interfaces. Direct, or nearly direct, bone apposition to implants occurred i...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580100201
更新日期:1979-10-01 00:00:00
abstract::Setting reactions and compressive strengths of a self-hardening calcium phosphate cement (CPC) were investigated. The CPC consists of tetracalcium phosphate (TTCP) and anhydrous dicalcium phosphate (DCPA). The cement specimens were prepared by mixing 0.7 g of the powder (TTCP 72.9 wt% + DCPA 27.1 wt%) with 0.175 mL of...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345900690121201
更新日期:1990-12-01 00:00:00
abstract::Periodontitis is a chronic inflammatory disease affecting oral tissues. The continuous, high production of cytokines by host cells triggered by periodontopathogens is thought to be responsible for the destruction of tooth-supporting tissues. Macrophages play a critical role in this host inflammatory response to period...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500306
更新日期:2006-03-01 00:00:00
abstract::Cultures of Streptococcus mutans MFe28 (serotype h) were grown with differing extracellular polysaccharide (EPS) content. Biochemical and physicochemical characteristics considered relevant to caries were measured. Acid production parameters measured in a pH-stat were: Vm = 0.76 +/- 0.14 mumol/g/sec (wet weight); appa...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670060101
更新日期:1988-06-01 00:00:00
abstract::Minimizing patient exposure while maintaining a diagnostically acceptable radiograph is a major goal in diagnostic radiography. Rare-earth filters may be the means to achieve this goal due to their "band-pass effect". The purpose of this study was to examine the image contrast effects and exposure reductions for vario...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660080701
更新日期:1987-08-01 00:00:00
abstract::Previous studies have shown that extracts of various filling materials, e.g., resin composites, may influence the growth of cariogenic micro-organisms. The purpose of this study was to examine the effects of important resin composite (co)monomers (Bis-GMA, UDMA, TEGDMA, EGDMA) and extracts of two commercial dental com...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345980770010601
更新日期:1998-01-01 00:00:00
abstract::Moderate elevation of serum C-reactive protein (CRP) is a risk factor for cardiovascular disease among apparently healthy individuals, although factors that create this inflammatory response in the absence of systemic illness have not been clarified. This study aimed to: (1) evaluate associations among periodontal dis...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790010701
更新日期:2000-01-01 00:00:00
abstract::Rat parotid atrophy, induced by liquid feeding over 10 days, was manifested as gland weight loss (40%) and histologically as acinar shrinkage. Acinar secretory function was investigated in the same glands using enzymatically dispersed cell preparations and superfused gland slices. Results were normalized for the acina...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345940730060901
更新日期:1994-06-01 00:00:00