Immunolocalization of PTCH protein in odontogenic cysts and tumors.

abstract：:In a previous experiment, we found that masseter muscle spindles show functional plasticity after 5 to 15 days under increased occlusal vertical dimension (iOVD). In the present study, we hypothesized that spindle function would eventually recover if longer observation periods were allowed. Therefore, in this study we...

journal_title：Journal of dental research

authors： Yabushita T,Zeredo JL,Fujita K,Toda K,Soma K

更新日期：2006-09-01 00:00:00

abstract：:The pellicle serves as a multifunctional protective layer, providing, e.g., lubrication and remineralization and also acting as a diffusion barrier. In addition, since the formation of the pellicle precedes the adhesion of micro-organisms, it is also important as a conditioning film. We present a novel approach to stu...

journal_title：Journal of dental research

authors： Sotres J,Pettersson T,Lindh L,Arnebrant T

更新日期：2012-10-01 00:00:00

abstract：:The maturation of dental enamel succeeds the degradation of organic matrix. Inhibition studies have shown that this degradation is accomplished by a serine-type proteinase. To isolate and characterize cDNA clones encoding this proteinase, we used two degenerate primer approaches to amplify part of the coding region us...

journal_title：Journal of dental research

authors： Simmer JP,Fukae M,Tanabe T,Yamakoshi Y,Uchida T,Xue J,Margolis HC,Shimizu M,DeHart BC,Hu CC,Bartlett JD

更新日期：1998-02-01 00:00:00

abstract：:Components of resin materials may damage DNA, leading to genetic alterations in mammalian cells. Here, monomers were analyzed for the induction of chromosomal aberrations indicated by micronuclei induced in V79 cells. A dose-related increase in the numbers of micronuclei was observed with triethyleneglycol dimethacryl...

journal_title：Journal of dental research

authors： Schweikl H,Schmalz G,Spruss T

更新日期：2001-07-01 00:00:00

abstract：:The aim of the present study was to describe the patterns of dental fluorosis in the primary and the permanent dentition of children born and reared in two different fluoridated areas, one in which powdered milk suspended in tap water was commonly used (Narssaq, Greenland: 1.1 ppm fluoride in the water) and one in whi...

journal_title：Journal of dental research

authors： Larsen MJ,Senderovitz F,Kirkegaard E,Poulsen S,Fejerskov O

更新日期：1988-05-01 00:00:00

abstract：:Since the exposure of mutans streptococci to xylitol is known to select for xylitol-resistant (XR) natural mutants, the occurrence and long-term survival of such xylitol-resistant strains was evaluated in a cross-sectional sampling of participants of the Ylivieska xylitol study four years after the original two-year e...

journal_title：Journal of dental research

authors： Trahan L,Söderling E,Dréan MF,Chevrier MC,Isokangas P

更新日期：1992-11-01 00:00:00

abstract：:The fatigue crack growth resistance of dentin was characterized as a function of depth from the dentino-enamel junction. Compact tension (CT) specimens were prepared from the crowns of third molars in the deep, middle, and peripheral dentin. The microstructure was quantified in terms of the average tubule dimensions a...

journal_title：Journal of dental research

authors： Ivancik J,Neerchal NK,Romberg E,Arola D

更新日期：2011-08-01 00:00:00

abstract：:Stem cells from exfoliated deciduous teeth (SHED) possess multipotent differentiation and immunomodulatory properties. They have been used for orofacial bone regeneration and autoimmune disease treatment. In this study, we show that acetylsalicylic acid (ASA) treatment is able to significantly improve SHED-mediated os...

journal_title：Journal of dental research

authors： Liu Y,Chen C,Liu S,Liu D,Xu X,Chen X,Shi S

更新日期：2015-01-01 00:00:00

abstract：:Caries of the permanent first molars of 5-year-old children was found to be associated with caries of their diciduous teeth. The sample consisted of 220 children whose permanent first molars had erupted. They were selected out of 965 children who were a representative sample of children attending compulsory kindergart...

journal_title：Journal of dental research

authors： Zadik D

更新日期：1976-11-01 00:00:00

abstract：:Early childhood caries (ECC) is a chronic disease affecting the oral health of children globally. This disease is multifactorial, but a primary factor is cariogenic microorganisms such as Streptococcus mutans. Biosynthetic gene clusters (BGCs) encode small molecules with diverse biological activities that influence th...

journal_title：Journal of dental research

authors： Momeni SS,Beno SM,Baker JL,Edlund A,Ghazal T,Childers NK,Wu H

更新日期：2020-07-01 00:00:00

abstract：:Hemifacial microsomia (HFM) is a congenital disorder marked by facial asymmetry. Whether facial asymmetry accounts for asymmetrical dental development is unknown. There are few data on dental development relative to mandibular development or severity of HFM, or on development over time. We hypothesized that when mandi...

journal_title：Journal of dental research

authors： Ongkosuwito EM,de Gijt P,Wattel E,Carels CE,Kuijpers-Jagtman AM

更新日期：2010-12-01 00:00:00

abstract：:A model system consisting of vacuum-deposited aluminum on glass was developed to demonstrate the effectiveness of cavitational activity (occurring within the cooling water supply of a dental ultrasonic scaler) in the removal of particulate material from solid surfaces. The amount of solid material removed from the mod...

journal_title：Journal of dental research

authors： Walmsley AD,Laird WR,Williams AR

更新日期：1984-09-01 00:00:00

abstract：:Due, in part, to the unique structure of the tooth, dental pain is initiated via distinct mechanisms. Here we review recent advances in our understanding of inflammatory tooth pain and discuss 3 hypotheses proposed to explain dentinal hypersensitivity: The first hypothesis, supported by functional expression of temper...

journal_title：Journal of dental research

authors： Chung G,Jung SJ,Oh SB

更新日期：2013-11-01 00:00:00

abstract：:A silver-plating technique was developed in an effort to produce good mechanical bonding characteristics between stainless steel pins and amalgam. Metallographic microscope and scanning electron microscope (SEM) studies were made to assess the presence, or otherwise, of such a bond between (a) the silver layer plating...

journal_title：Journal of dental research

authors： Galindo Y,McLachlan K,Kasloff Z

更新日期：1980-02-01 00:00:00

abstract：:Human tooth wear occurs so slowly that traditionally it has needed months or years to be measurable. This study showed that microscopic changes in wear patterns on human teeth could be detected in a matter of days and could be used as indicators of rates of wear. Thus, daily or weekly changes in rates of wear can be d...

journal_title：Journal of dental research

authors： Teaford MF,Tylenda CA

更新日期：1991-03-01 00:00:00

abstract：:Thermal diffusivity, a property related to the thermal insulative efficiency of a material, was measured in nine glass-ionomer cements and compared with results from a silicate and a polycarboxylate cement. Each cement was mixed at various powder-liquid ratios (P/L) and moulded into a rectangular prism of approximate ...

journal_title：Journal of dental research

authors： Tay WM,Braden M

更新日期：1987-05-01 00:00:00

abstract：:Mutations in ALPL result in hypophosphatasia (HPP), a disease causing defective skeletal mineralization. ALPL encodes tissue nonspecific alkaline phosphatase (ALP), an enzyme that promotes mineralization by reducing inorganic pyrophosphate, a mineralization inhibitor. In addition to skeletal defects, HPP causes dental...

journal_title：Journal of dental research

authors： Foster BL,Sheen CR,Hatch NE,Liu J,Cory E,Narisawa S,Kiffer-Moreira T,Sah RL,Whyte MP,Somerman MJ,Millán JL

更新日期：2015-05-01 00:00:00

abstract：:The balance between bone resorption and bone formation is vital for maintenance and regeneration of alveolar bone and supporting structures around teeth and dental implants. Tissue regeneration in the oral cavity is regulated by multiple cell types, signaling mechanisms, and matrix interactions. A goal for periodontal...

journal_title：Journal of dental research

authors： Larsson L,Decker AM,Nibali L,Pilipchuk SP,Berglundh T,Giannobile WV

更新日期：2016-03-01 00:00:00

abstract：:The study of biofilm structure and function mandates the use of model systems for which a host of environmental variables can be rigorously controlled. We describe a model of supragingival plaque containing Actinomyces naeslundii, Veillonella dispar, Fusobacterium nucleatum, Streptococcus sobrinus, and Streptococcus o...

journal_title：Journal of dental research

authors： Guggenheim B,Giertsen E,Schüpbach P,Shapiro S

更新日期：2001-01-01 00:00:00

abstract：:The acquired dental pellicle helps prevent erosion, but the protection level is unknown. This in situ study tested whether a two-hour pellicle protects against different erosive challenges by orange juice. Subjects wore palatal appliances loaded with either enamel or dentin specimens. Pellicle was allowed to form, or ...

journal_title：Journal of dental research

authors： Hara AT,Ando M,González-Cabezas C,Cury JA,Serra MC,Zero DT

更新日期：2006-07-01 00:00:00

abstract：:Cultures of Streptococcus mutans MFe28 (serotype h) were grown with differing extracellular polysaccharide (EPS) content. Biochemical and physicochemical characteristics considered relevant to caries were measured. Acid production parameters measured in a pH-stat were: Vm = 0.76 +/- 0.14 mumol/g/sec (wet weight); appa...

journal_title：Journal of dental research

authors： Dibdin GH,Shellis RP

更新日期：1988-06-01 00:00:00

abstract：:Antigenic alterations to the dentin organic matrix may be detected by an immunohistochemical approach. We hypothesized that alterations in the antigenicity of type I collagen and proteoglycans occur in sclerotic dentin under caries lesions. Transverse sections were prepared from carious teeth in the sclerotic zone and...

journal_title：Journal of dental research

authors： Suppa P,Ruggeri A Jr,Tay FR,Prati C,Biasotto M,Falconi M,Pashley DH,Breschi L

更新日期：2006-02-01 00:00:00

abstract：:Khat-chewing has been associated with oral lesions including oral cancer, but the mechanisms leading to their development are not known. We hypothesized that khat interferes with the physiological processes of the oral mucosa, such as cell proliferation and differentiation, and aimed at investigating the effects of kh...

journal_title：Journal of dental research

authors： Lukandu OM,Neppelberg E,Vintermyr OK,Johannessen AC,Costea DE

更新日期：2010-03-01 00:00:00

abstract：:Dental epithelial progenitor cells differentiate into various cell types during development of tooth germs. To study this mechanism, we produced immortalized dental epithelial progenitor cells derived from the cervical-loop epithelium of a rat lower incisor. The expression patterns of cytokeratin 14, nerve growth fact...

journal_title：Journal of dental research

authors： Kawano S,Saito M,Handa K,Morotomi T,Toyono T,Seta Y,Nakamura N,Uchida T,Toyoshima K,Ohishi M,Harada H

更新日期：2004-02-01 00:00:00

abstract：:It was recently reported that human periapical cysts (hPCys), a commonly occurring odontogenic cystic lesion of inflammatory origin, contain mesenchymal stem cells (MSCs) with the capacity for self-renewal and multilineage differentiation. In this study, periapical inflammatory cysts were compared with dental pulp to ...

journal_title：Journal of dental research

authors： Marrelli M,Paduano F,Tatullo M

更新日期：2015-06-01 00:00:00

abstract：:Amelogenin and ameloblastin, the major enamel matrix proteins, are important for enamel mineralization. To identify their synergistic roles in enamel development, we generated Amel X(-/-)/Ambn(-/-) mice. These mice showed additional enamel defects in comparison with Amel X(-/-) or Ambn(-/-) mice. In 7-day-old Amel X(-...

journal_title：Journal of dental research

authors： Hatakeyama J,Fukumoto S,Nakamura T,Haruyama N,Suzuki S,Hatakeyama Y,Shum L,Gibson CW,Yamada Y,Kulkarni AB

更新日期：2009-04-01 00:00:00

abstract：:The regulation of blood flow of the dental pulp was investigated in dogs and rats anesthetized with sodium pentobarbital. Pulpal blood flow was altered by variations of local and systemic hemodynamics. Variation in pulpal hemodynamics was attained by means of close intra-arterial injections of adrenergic agonists (NE ...

journal_title：Journal of dental research

authors： Kim S

更新日期：1985-04-01 00:00:00

abstract：:Polynomial and catenary equations were fit by least square error methods to the dentitions of seven children with "normal" occlusion. Mean and mean square error were then used to analyze accuracy of curve fits and asymmetries of arches. A lack of congruency for the "lines of occlusion" common to the maxilla and mandib...

journal_title：Journal of dental research

authors： Pepe SH

更新日期：1975-11-01 00:00:00

abstract：:The destabilizing effect of endodontic treatment upon teeth is still controversial. The purpose of this study was to investigate the effects of different steps of endodontic treatments upon the rigidity of teeth. Extracted untreated central maxillary anterior teeth were loaded (3.75 N), and deformations of the root we...

journal_title：Journal of dental research

authors： Lang H,Korkmaz Y,Schneider K,Raab WH

更新日期：2006-04-01 00:00:00

abstract：:Local anesthetic agents may be classified according to their intrinsic anesthetic potency and duration of activity. Procaine and chloroprocaine are relatively weak, short-acting drugs. Lidocaine, mepivacaine, and prilocaine represent agents of intermediate potency and duration of action. Tetracaine, bupivacaine, and e...

journal_title：Journal of dental research

authors： Covino BG,Giddon DB

更新日期：1981-08-01 00:00:00