Validation of an in vitro biofilm model of supragingival plaque.

abstract：:The effect of different doses of polyadenylic and polyuridylic acids (poly A:U) was studied in control rats and in rats exposed to hypoxia. In the control rats, administration of different doses of poly A:U did not change the thickness of the epiphyseal plate or increase the incorporation of 3H-phenylalanine as judged...

journal_title：Journal of dental research

authors： Koo CS,Kim MK,Han SS

更新日期：1976-07-01 00:00:00

abstract：:Angiogenesis and biomineral substrates play major roles in bone development and regeneration. We hypothesized that macroporous scaffolds of biomineralized 85:15 poly(lactide-co-glycolide), which locally release vascular endothelial growth factor-165 (VEGF), would direct simultaneous regeneration of bone and vascular t...

journal_title：Journal of dental research

authors： Murphy WL,Simmons CA,Kaigler D,Mooney DJ

更新日期：2004-03-01 00:00:00

abstract：:Heads of Swiss-Webster mouse fetuses of four ages spanning days 12-13 of gestation, were partially dissected by removing the brain (B), tongue (T) and mandible (M) alone or in combination (BT, BM, BTM). Preparations were suspended in a gassed, circulating culture system such that palatal closure must take place agains...

journal_title：Journal of dental research

authors： Brinkley L,Basehoar G,Avery J

更新日期：1978-02-01 00:00:00

abstract：:The anticaries effect of professional fluoride (F) application has been attributed to calcium-fluoride-like deposits (CaF(2)) formed on enamel, but this has not been clearly demonstrated. We hypothesized that CaF(2) formed on plaque-free enamel by F application would reduce enamel demineralization due to the increase ...

journal_title：Journal of dental research

authors： Tenuta LM,Cerezetti RV,Del Bel Cury AA,Tabchoury CP,Cury JA

更新日期：2008-11-01 00:00:00

abstract：:The universally accepted concept of delay-loaded dental implants has recently been challenged. This study hypothesizes that early loading (decreased implant healing time) leads to increased bone formation and decreased crestal bone loss. We used 17 minipigs to study implants under a controlled load, with non-loaded im...

journal_title：Journal of dental research

authors： Ko CC,Douglas WH,DeLong R,Rohrer MD,Swift JQ,Hodges JS,An KN,Ritman EL

更新日期：2003-08-01 00:00:00

abstract：:Early-onset periodontitis (EOP) is considered to have a genetic basis which has not been clearly defined. Genetic polymorphisms of the vitamin D receptor (VDR-B-b) and the immunoglobulin-Fc-gamma receptor IIIb (FcgammaRIIIb-NA1-NA2) are associated with bone metabolism and infectious diseases, respectively. The purpose...

journal_title：Journal of dental research

authors： Yoshihara A,Sugita N,Yamamoto K,Kobayashi T,Miyazaki H,Yoshi H

更新日期：2001-12-01 00:00:00

abstract：:Dental amalgam restorations are a significant source of mercury exposure in the human population, but their potential to cause systemic health effects is highly disputed. We examined effects on the immune system by giving genetically mercury-susceptible Brown Norway (BN) rats and mercury-resistant Lewis (LE) rats silv...

journal_title：Journal of dental research

authors： Hultman P,Lindh U,Hörsted-Bindslev P

更新日期：1998-06-01 00:00:00

abstract：:Recent reports have suggested functional interactions between the masticatory and head motor systems. However, the neurophysiological mechanisms behind these phenomena have not been thoroughly investigated. In this study, the motor unit activity was recorded bilaterally from the dorsal neck splenius muscles (SPL) whil...

journal_title：Journal of dental research

authors： Zeredo JL,Toda K,Soma K

更新日期：2003-05-01 00:00:00

abstract：:During the polymerization of multifunctional monomers for dental restorations, typical final double-bond conversions range from 55 to 75%. The low conversion results in a large amount of extractable monomer, reduced adhesion to the filler, and the potential for increased swelling. In this work, the ability to increase...

journal_title：Journal of dental research

authors： Anseth KS,Goodner MD,Reil MA,Kannurpatti AR,Newman SM,Bowman CN

更新日期：1996-08-01 00:00:00

abstract：:Autonomic and behavioral responses to seven dental procedures were studied in 21 pedodontic patients aged six to 12. When mean pulse rate, pulse amplitude, absolute skin conductance, and skin-conductance responses were compared over all subjects, the injection of the local anesthetic consistently elicited the greatest...

journal_title：Journal of dental research

authors： West GA,Reid KH,Bastawi AE

更新日期：1983-06-01 00:00:00

abstract：:Better understanding of dental caries and other oral conditions has guided new strategies to prevent disease and manage its consequences at individual and public health levels. This article discusses advances in prevention and minimal intervention dentistry over the last century by focusing on some milestones within s...

journal_title：Journal of dental research

authors： Innes NPT,Chu CH,Fontana M,Lo ECM,Thomson WM,Uribe S,Heiland M,Jepsen S,Schwendicke F

更新日期：2019-06-01 00:00:00

abstract：:Incubation of saliva supernatant after three hours at 37 C revealed that salivary anionic proteins were susceptible to enzymatic attack by salivary enzymes not removable by centrifugation at 10,000 g. In the presence of washed suspensions of S mutans or S sanguis additional changes in electrophoretic behavior of anion...

journal_title：Journal of dental research

authors： Cowman RA,Fitzgerald RJ

更新日期：1975-03-01 00:00:00

abstract：:Using a pin-on-disc sliding-wear test apparatus, the wear behavior of a typical composite restorative vs. styli fashioned from human enamel, sintered alumina, and magnesium fluoride was examined. The rates of restorative wear were found to be identical, within the experimental error of the measurements, for tests usin...

journal_title：Journal of dental research

authors： Rice SL,Bailey WF,Roto M,Wayne SF

更新日期：1984-06-01 00:00:00

abstract：:The pellicle serves as a multifunctional protective layer, providing, e.g., lubrication and remineralization and also acting as a diffusion barrier. In addition, since the formation of the pellicle precedes the adhesion of micro-organisms, it is also important as a conditioning film. We present a novel approach to stu...

journal_title：Journal of dental research

authors： Sotres J,Pettersson T,Lindh L,Arnebrant T

更新日期：2012-10-01 00:00:00

abstract：:Pieces of fresh rat incisor enamel were extracted with various buffer solutions and prepared for electron microscopy. I observed partial or complete removal of organic constituents, shrinkage of rods and interrods, separation of stippled material from the enamel, and partial decalcification. The results modify the con...

journal_title：Journal of dental research

authors： Kallenbach E

更新日期：1982-12-01 00:00:00

abstract：:Squamous cell carcinoma (SCC) of the head and neck is the sixth most frequent cancer worldwide. The survival rate is among the lowest of the major cancers and has not improved significantly in the past two decades. Extensive local invasion and regional lymph node metastasis are, in large part, responsible for the poor...

journal_title：Journal of dental research

authors： Crowe DL,Milo GE,Shuler CF

更新日期：1999-06-01 00:00:00

abstract：:The purpose of this investigation was to determine whether chlorhexidine combined with copper would exert a synergistic, growth-inhibitory effect against selected oral bacteria. Actinomyces viscosus, Actinomyces naeslundii, and Streptococcus mutans were all susceptible to chlorhexidine individually, with S. mutans dis...

journal_title：Journal of dental research

authors： Drake DR,Grigsby W,Cardenzana A,Dunkerson D

更新日期：1993-02-01 00:00:00

abstract：:Locally applied bisphosphonates may improve the fixation of metal implants in bone. However, systemic bisphosphonate treatment is associated with a risk of osteonecrosis of the jaw (ONJ). We hypothesized that local delivery of bisphosphonate from the implant surface improves the fixation of dental implants without com...

journal_title：Journal of dental research

authors： Abtahi J,Agholme F,Sandberg O,Aspenberg P

更新日期：2013-03-01 00:00:00

abstract：:Diet is recognized as one of the most important factors affecting the equilibrium of the oral bacterial flora. Studies related to dental caries development have focused mainly on the effect of carbohydrates. In the present work, using swabbing coupled with an immuno-colony-blot assay, we followed the indigenous oral b...

journal_title：Journal of dental research

authors： Blais JF,Lavoie MC

更新日期：1990-03-01 00:00:00

abstract：:The distribution of immunoglobulin-containing cells in human tonsils, salivary glands, and inflamed gingiva is described. The cellular localization of J chain indicates that this peptide is a basic gene product of B cells that is expressed only in the early phase of clonal differentiation. Gland-associated immunocytes...

journal_title：Journal of dental research

authors： Brandtzaeg P

更新日期：1976-04-01 00:00:00

abstract：:Enamel demineralization adjacent to pit and fissure sealants leads to the formation of marginal caries, which can necessitate the replacement of existing sealants. Dental materials with bioactive glass, which releases ions that inhibit dental caries, have been studied. The purpose of this study was to evaluate the ena...

journal_title：Journal of dental research

authors： Yang SY,Kwon JS,Kim KN,Kim KM

更新日期：2016-05-01 00:00:00

abstract：:The bactericidal effect of hexylresorcinol was assessed using bacterial aggregates. Increased drug concentration resulted in decreased survival of bacteria when the aggregates were exposed to hexylresorcinol for at least eight hours. This indicates that this drug may be effective against dental plaque only when availa...

journal_title：Journal of dental research

authors： Kraal JH,Hussain AA,Gregorio SB,Akaho E

更新日期：1979-11-01 00:00:00

abstract：:15-deoxy-Delta(12,14)-prostaglandin J(2) (15-d-PGJ(2)) and troglitazone have been shown to induce apoptosis in several carcinoma cell lines. However, apoptotic signaling pathways of these agents are poorly understood. We tested the hypothesis that peroxisome proliferator-activated receptor-gamma ligands such as these ...

journal_title：Journal of dental research

authors： Fukuchi K,Date M,Azuma Y,Shinohara M,Takahashi H,Ohura K

更新日期：2003-10-01 00:00:00

abstract：:A numerical model of the mandible, its articulating surfaces, and the forces exerted by the primary masticatory muscles has been developed for the purpose of investigating loading of the temporomandibular joint. Evidence is presented which shows that the temporomandibular joint. Evidence is presented which shows that ...

journal_title：Journal of dental research

authors： Smith DM,McLachlan KR,McCall WD Jr

更新日期：1986-08-01 00:00:00

abstract：:Samples of dental plaque obtained from the interproximal tooth surfaces of seven young men showed considerable variation in the prevalence and anatomic site distribution of the potentially cariogenic microorganism S mutans. Multiple application of 10% SnF2 topical solution and saline solution delivered to interproxima...

journal_title：Journal of dental research

authors： Keene HJ,Shklair IL,Mickel GJ

更新日期：1977-01-01 00:00:00

abstract：:An oral radiotelemetric technique was used to determine whether a range of efficient buffers had the capacity to control the levels of hydrogen ions within dental plaque in the presence of sucrose. It was found that the buffers failed to control both the intensity and duration of the acid produced. ...

journal_title：Journal of dental research

authors： Clarke NG,Dowdell LR

更新日期：1976-09-01 00:00:00

abstract：:Odontoblasts, with their strategic arrangement along the outermost compartment of the dentin-pulp complex, have been suggested to have sensory function. In addition to their primary role in dentin formation, growing evidence shows that odontoblasts are capable of sensing mechanical stimulation. Previously, we found th...

journal_title：Journal of dental research

authors： Won J,Vang H,Kim JH,Lee PR,Kang Y,Oh SB

更新日期：2018-08-01 00:00:00

abstract：:The tissue-implant interfaces of functional and non-functional endosseous dental implants were compared histologically for up to one year post-operatively. Nonmineralized connective tissue zones (a "fibrous capsule") existed in all functional interfaces. Direct, or nearly direct, bone apposition to implants occurred i...

journal_title：Journal of dental research

authors： Brunski JB,Moccia AF Jr,Pollack SR,Korostoff E,Trachtenberg DI

更新日期：1979-10-01 00:00:00

abstract：:This study contains the first part of a research project in which the applicability of fracture mechanics parameters to predict failure of a restored tooth was investigated. Fracture mechanics parameters have been used in dental research before, but were restricted to comparative studies between various brands of comp...

journal_title：Journal of dental research

authors： De Groot R,Van Elst HC,Peters MC

更新日期：1988-06-01 00:00:00

abstract：:Various etching methods are examined with respect to their ability to induce the surface nucleation and growth of fluorapatite from solutions of low, sustained supersaturation with respect to hydroxyapatite and fluorapatite. The constant composition kinetics method enables the rates of remineralization to be precisely...

journal_title：Journal of dental research

authors： Amjad Z,Koutsoukos PG,Nancollas GH

更新日期：1982-09-01 00:00:00