Cellular and molecular mechanisms of dental nociception.

abstract：:Titanium-polymethacrylate composite was prepared as an x-ray-opaque filler for composite core materials. The base monomers of the composite were 2,2-bis [4-(3-methacryloyloxy-2-hydroxypropoxy) phenyl] propane (Bis-GMA) and triethyleneglycol dimethacrylate (TEGDMA). Pure titanium powder was used as a radiopaque element...

journal_title：Journal of dental research

authors： Matsumura H,Sueyoshi M,Atsuta M

更新日期：1992-01-01 00:00:00

abstract：:Bisphosphonates are a class of agents used to treat osteoporosis and malignant bone metastases. The efficacy of these agents in treating and preventing the significant skeletal complications associated with these conditions has had a major positive impact for patients and is responsible for their widespread use in med...

journal_title：Journal of dental research

authors： Ruggiero SL,Drew SJ

更新日期：2007-11-01 00:00:00

abstract：:The temporal and spatial patterns in which teeth are initiated in the growing jaws of embryos are constant for a species but different for different species. The sources of the patterns have been explained in two ways. First, they are the outcome of reactions between molecules created at stationary targets and those w...

journal_title：Journal of dental research

authors： Osborn JW

更新日期：1998-09-01 00:00:00

abstract：:A double-blind randomized clinical trial was performed in 6- to 7-yr-old schoolchildren to evaluate, in a 30-mo period, whether the caries increment on the distal surface of the second primary molars adjacent to permanent first molars sealed with fluoride release compounds would be lower with respect to those adjacent...

journal_title：Journal of dental research

authors： Cagetti MG,Carta G,Cocco F,Sale S,Congiu G,Mura A,Strohmenger L,Lingström P,Campus G,Italian Experimental Group on Oral Health.

更新日期：2014-07-01 00:00:00

abstract：:The etiology and pathogenesis of craniofacial birth defects are multifactorial and include both genetic and environmental factors. Despite the identification of numerous genes associated with congenital craniofacial anomalies, our understanding of their etiology remains incomplete, and many affected individuals have a...

journal_title：Journal of dental research

authors： Dash S,Bhatt S,Falcon KT,Sandell LL,Trainor PA

更新日期：2020-11-06 00:00:00

abstract：:Ten dental casting alloys were tested for alloy-element release into cell-culture medium, and this release was related to alloy composition, alloy microstructure, and alloy cytotoxicity (previously determined). Cell-culture medium was analyzed for alloy elements by flame atomic absorption. Concentrations of elements i...

journal_title：Journal of dental research

authors： Wataha JC,Craig RG,Hanks CT

更新日期：1991-06-01 00:00:00

abstract：:Resin composites currently available are not suitable for use as large stress-bearing posterior restorations involving cusps due to their tendencies toward excessive fracture and wear. The glass fillers in composites provide only limited reinforcement because of the brittleness and low strength of glass. The aim of th...

journal_title：Journal of dental research

authors： Xu HH,Martin TA,Antonucci JM,Eichmiller FC

更新日期：1999-02-01 00:00:00

abstract：:Patients with cleft lip/palate (CLP) have been reported, in some studies, to exhibit an increased prevalence of caries, although the underlying cause for this increase is unknown. In genetically defined mouse models, studies of postnatal sequelae associated with CLP have been hampered by neonatal lethality. Using a co...

journal_title：Journal of dental research

authors： Tamasas B,Cox TC

更新日期：2017-03-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs (NSAIDs) are used to manage pain and inflammatory disorders. We hypothesized that gingival fibroblasts actively accumulate NSAIDs and enhance their levels in gingival connective tissue. Using fluorescence to monitor NSAID transport, we demonstrated that cultured gingival fibroblas...

journal_title：Journal of dental research

authors： Zavarella MM,Gbemi O,Walters JD

更新日期：2006-05-01 00:00:00

abstract：:In 1986, the first nationwide epidemiological survey of adult oral health and attitudes to oral health care was carried out in The Netherlands. One of the aims of this study was to evaluate the prevalence and the quality (in terms of need for replacement) of amalgam and composite restorations in the Dutch adult popula...

journal_title：Journal of dental research

authors： Kroeze HJ,Plasschaert AJ,van 't Hof MA,Truin GJ

更新日期：1990-06-01 00:00:00

abstract：:Four classes of elastomeric impression materials (polysulfide, polyether, silicone, and agar-agar) were evaluated on the basis of linear dimensional stability as a function of time between taking and pouring an impression of mounted teeth. Four polysulfide materials produced dies which were larger than the teeth and g...

journal_title：Journal of dental research

authors： Marcinak CF,Young FA,Draughn RA,Flemming WR

更新日期：1980-07-01 00:00:00

abstract：:The purpose of this study was to investigate the mechanism of surface layer formation in artificial white spots. Two nondestructive nuclear micro-analysis techniques were employed to analyze windows of human dental enamel at progressive stages of an artificial lesion. Fluoride concentrations were measured to a depth o...

journal_title：Journal of dental research

authors： Crawford AW,de Bruin HJ

更新日期：1983-09-01 00:00:00

abstract：:The whisker pad area (WP) is innervated by the second branch of the trigeminal nerve and experiences allodynia and hyperalgesia following transection of the mental nerve (MN; the third branch of the trigeminal nerve). However, the mechanisms of this extra-territorial pain remain unclear. The ionotropic P2X(7) ATP rece...

journal_title：Journal of dental research

authors： Murasaki K,Watanabe M,Takahashi K,Ito G,Suekawa Y,Inubushi T,Hirose N,Uchida T,Tanne K

更新日期：2013-03-01 00:00:00

abstract：:The flexure moduli of elasticity of solid and multi-stranded orthodontic wires were determined. Results for the solid wires approximated their tensile values, but the differences were statistically significant for the stainless steel, chromium-cobalt-nickel, and nickel-titanium alloys. The flexure moduli of the multi-...

journal_title：Journal of dental research

authors： Goldberg AJ,Morton J,Burstone CJ

更新日期：1983-07-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) plays a crucial role in the modulation of orofacial pain, and we hypothesized that CGRP mediated a neuron-glia crosstalk in orofacial pain. The objective of this study was to elucidate the mechanisms whereby CGRP mediated trigeminal neuron-glia crosstalk in modulating orofacial p...

journal_title：Journal of dental research

authors： Liang H,Hu H,Shan D,Lyu J,Yan X,Wang Y,Jian F,Li X,Lai W,Long H

更新日期：2021-01-01 00:00:00

abstract：:The tongue plays an important role in mastication and swallowing by its contact with the hard palate. Using an experimental palatal plate with 7 pressure sensors, and recording jaw movement using mandibular kinesiography, we assessed, in healthy subjects, the coordination of tongue and jaw movements during the entire ...

journal_title：Journal of dental research

authors： Hori K,Ono T,Nokubi T

更新日期：2006-02-01 00:00:00

abstract：:Three dental amalgams were investigated to determine if their abrasion resistance was significantly affected by different packing pressures. Abrasive wear tests were performed on a machine designed to test materials under conditions similar to masticatory function. The results show that the abrasion resistance of the ...

journal_title：Journal of dental research

authors： Harrison A

更新日期：1977-06-01 00:00:00

abstract：:Symphyseal secondary cartilage is important for mandibular development, but the molecular mechanisms underlying its formation remain largely unknown. Here we asked whether Indian hedgehog (Ihh) regulates symphyseal cartilage development and growth. By embryonic days 16.5 to 18.5, Sox9-expressing chondrocytes formed wi...

journal_title：Journal of dental research

authors： Sugito H,Shibukawa Y,Kinumatsu T,Yasuda T,Nagayama M,Yamada S,Minugh-Purvis N,Pacifici M,Koyama E

更新日期：2011-05-01 00:00:00

abstract：:Cultures of Streptococcus mutans MFe28 (serotype h) were grown with differing extracellular polysaccharide (EPS) content. Biochemical and physicochemical characteristics considered relevant to caries were measured. Acid production parameters measured in a pH-stat were: Vm = 0.76 +/- 0.14 mumol/g/sec (wet weight); appa...

journal_title：Journal of dental research

authors： Dibdin GH,Shellis RP

更新日期：1988-06-01 00:00:00

abstract：:Using a hydraulic bellows system mounted on a maxillary partial denture, continuous force-displacement data were taken in an edentulous area in the maxillary bicuspid-molar region on ten adults. Both loading and unloading force-displacement curves showed three segments. Two visco-elastic properties - hysteresis and re...

journal_title：Journal of dental research

authors： Ho TP,Weinstein S,Bowley WW

更新日期：1984-10-01 00:00:00

abstract：:Understanding the mechanical properties of human teeth is important to clinical tooth preparation and to the development of "tooth-like" restorative materials. Previous studies have focused on the macroscopic fracture behavior of enamel and dentin. In the present study, we performed indentation studies to understand t...

journal_title：Journal of dental research

authors： Xu HH,Smith DT,Jahanmir S,Romberg E,Kelly JR,Thompson VP,Rekow ED

更新日期：1998-03-01 00:00:00

abstract：:Dickkopf-related protein 1 (DKK1) is a potent inhibitor of Wnt/β-catenin signaling. Dkk1-null mutant embryos display severe defects in head induction. Conversely, targeted expression of Dkk1 in dental epithelial cells leads to the formation of dysfunctional enamel knots and subsequent tooth defects during embryonic de...

journal_title：Journal of dental research

authors： Han XL,Liu M,Voisey A,Ren YS,Kurimoto P,Gao T,Tefera L,Dechow P,Ke HZ,Feng JQ

更新日期：2011-11-01 00:00:00

abstract：:Although osteoporosis is a major public health concern, the effect of this condition on oral bone has not been determined. Using the ovariectomized rat as a model, we examined whether acute estrogen depletion affects the mandible of the ovariectomized rat with and without maxillary molar extraction. Twenty-two ovariec...

journal_title：Journal of dental research

authors： Elovic RP,Hipp JA,Hayes WC

更新日期：1994-11-01 00:00:00

abstract：:The classic stimulus for cellular cytokine production is bacterial lipopolysaccharide (endotoxin). It was therefore hypothesized that tumor necrosis factor-alpha (TNF-alpha) may be responsible for pericoronitis. TNF-alpha and its receptors were detected by immunohistochemical staining in third molar pericoronitis in t...

journal_title：Journal of dental research

authors： Beklen A,Laine M,Ventä I,Hyrkäs T,Konttinen YT

更新日期：2005-12-01 00:00:00

abstract：:Damage to the dentin matrix investigates the proliferation and mobilization of dental progenitor cells to the injury site, the mechanisms of which are not defined. EphB receptors and ephrin-B ligands expressed within the perivascular niche of dental pulp have been implicated following tooth injury. We propose that ele...

journal_title：Journal of dental research

authors： Arthur A,Koblar S,Shi S,Gronthos S

更新日期：2009-09-01 00:00:00

abstract：:Current knowledge regarding the sensitivity of the teeth to forces is based on psychophysical experiments that measured touch detection thresholds under static jaw conditions. It is not known whether jaw movements alter the perception of forces applied to the teeth, but, based on limb movement studies, it is hypothesi...

journal_title：Journal of dental research

authors： Sowman PF,Brinkworth RS,Türker KS

更新日期：2010-04-01 00:00:00

abstract：:The effect of combined administration of chlorhexidine and fluoride in the drinking water of hamsters on plaque and caries prevention was studied. Plaque indices of the hamsters receiving chlorhexidine either alone or simultaneously with fluoride were significantly lower than those of the control and fluoride only tre...

journal_title：Journal of dental research

authors： Brayer L,Gedalia I,Gover A

更新日期：1977-11-01 00:00:00

abstract：:Artificial white spot lesions have been prepared on bovine enamel surfaces by the controlled addition of lactate buffer containing methylhydroxydiphosphonate ions. The rates of remineralization have been measured using a constant composition method in solutions of calcium phosphate of low supersaturation. Deposition o...

journal_title：Journal of dental research

authors： de Rooij JF,Nancollas GH

更新日期：1984-06-01 00:00:00

abstract：:Although dental amalgam is used frequently under artificial crowns for restoration of severely damaged teeth, there is little information available on the bond between luting cements and this alloy. This study was designed for determination of the strength of the bond between a dental amalgam alloy and three crown-lut...

journal_title：Journal of dental research

authors： Mojon P,Hawbolt EB,MacEntee MI,Belser UC

更新日期：1989-11-01 00:00:00

abstract：:Chemical bonding between dental porcelains and alloys results from interdiffusion of porcelain and metal ions. An interfacial diffusion zone is created which, most likely, has properties different from those of bulk materials. The changed interface might affect experimental measurements of thermo-mechanical strain. To...

journal_title：Journal of dental research

authors： Tesk JA,Hinman RW,Widera GE,Holmes AD,Cassel JM

更新日期：1983-05-01 00:00:00