The formation and remineralization of artificial white spot lesions: a constant composition approach.

abstract：:Proteolytic hydrolysis of casein and porcine or bovine glycoproteins by S mutans was demonstrated in the present study. Caseinolytic activity was found in both the soluble contents of the cells and the cellular debris after rupture of the cells. However, caseinolytic activity could not be demonstrated after growth in ...

journal_title：Journal of dental research

authors： Cowman RA,Perrella MM,Fitzgerald RJ

更新日期：1976-05-01 00:00:00

abstract：:Administration of indomethacin inhibited the appearance of osteoclasts and bone resorption induced by experimental tooth movement in rats. Effects were limited to groups injected within 12 h after treatment. Prostaglandin E1 or E2 solutions injected in gingiva lying near the upper first molar caused the appearance of ...

journal_title：Journal of dental research

authors： Yamasaki K,Miura F,Suda T

更新日期：1980-10-01 00:00:00

abstract：:Human tooth wear occurs so slowly that traditionally it has needed months or years to be measurable. This study showed that microscopic changes in wear patterns on human teeth could be detected in a matter of days and could be used as indicators of rates of wear. Thus, daily or weekly changes in rates of wear can be d...

journal_title：Journal of dental research

authors： Teaford MF,Tylenda CA

更新日期：1991-03-01 00:00:00

abstract：:We have investigated the role of the activation of nuclear poly(ADP-ribose) polymerase (PARP) enzyme, a mediator of downstream nitric oxide toxicity, using a combined approach of pharmacological inhibition and genetic disruption in a ligature-induced-periodontitis model in rats and mice. Immunohistochemical analysis r...

journal_title：Journal of dental research

authors： Lohinai Z,Mabley JG,Fehér E,Marton A,Komjáti K,Szabó C

更新日期：2003-12-01 00:00:00

abstract：:Although proanthocyanidins (PACs) modify dentin, the effectiveness of different PAC sources and the correlation with their specific chemical composition are still unknown. This study describes the chemical profiling of natural PAC-rich extracts from 7 plants using ultra high pressure/performance liquid chromatography ...

journal_title：Journal of dental research

authors： Aguiar TR,Vidal CM,Phansalkar RS,Todorova I,Napolitano JG,McAlpine JB,Chen SN,Pauli GF,Bedran-Russo AK

更新日期：2014-04-01 00:00:00

abstract：:As an approach for improving the outcome and predictability of periodontal regenerative therapies, we have focused on determining the responses of cells within the local environment to putative regenerative factors. This study examined the effects of bone morphogenetic protein-2 (BMP-2) on murine cementoblasts in vitr...

journal_title：Journal of dental research

authors： Zhao M,Berry JE,Somerman MJ

更新日期：2003-01-01 00:00:00

abstract：:The rate of F absorption from the stomach is pH-dependent, with greater absorption at low pH. Since the rate of absorption is also strongly influenced by the rapidity of gastric emptying, we have compared the relative importance of gastric acidity and gastric emptying in overall F absorption. Male rats (350 g, n = 85)...

journal_title：Journal of dental research

authors： Messer HH,Ophaug RH

更新日期：1993-03-01 00:00:00

abstract：:The Global Burden of Disease (GBD) 2010 Study produced comparable estimates of the burden of 291 diseases and injuries in 1990, 2005, and 2010. This article reports on the global burden of untreated caries, severe periodontitis, and severe tooth loss in 2010 and compares those figures with new estimates for 1990. We u...

journal_title：Journal of dental research

authors： Marcenes W,Kassebaum NJ,Bernabé E,Flaxman A,Naghavi M,Lopez A,Murray CJ

更新日期：2013-07-01 00:00:00

abstract：:Fibroblast growth factor receptor 2 (FGFR2) in craniofacial bones mediates osteoprogenitor proliferation, differentiation, and apoptosis. The distortion of proper craniofacial bone growth may cause class II and class III skeletal malocclusion and result in compromised function and aesthetics. Here, we investigated the...

journal_title：Journal of dental research

authors： Jiang Q,Mei L,Zou Y,Ding Q,Cannon RD,Chen H,Li H

更新日期：2019-11-01 00:00:00

abstract：:Streptococcus mutans produces 3 types of glucosyltransferase (GTF), whose cooperative action is considered to be essential for its cellular adherence to the tooth surface. However, the precise mechanisms for synthesizing adhesive glucans and the specific roles of each GTF in cellular adherence to smooth surfaces have ...

journal_title：Journal of dental research

authors： Ooshima T,Matsumura M,Hoshino T,Kawabata S,Sobue S,Fujiwara T

更新日期：2001-07-01 00:00:00

abstract：:After cheek pouch carcinomas were induced in hamsters by the application of dimethylbenzanthracene (DMBA) to the right pouch for 13 weeks, the animals were divided into four groups and observed for seven more weeks. The control group received no further treatment, two experimental groups had incisional biopsies perfor...

journal_title：Journal of dental research

authors： Tsiklakis K,Wood NK,Toto PD,Doemling DB

更新日期：1986-06-01 00:00:00

abstract：:The dentition in zebrafish is extremely and richly vascularized, but the function of the vasculature, in view of the continuous replacement of the teeth, remains elusive. Through application of SU5416, a vascular endothelial growth factor receptor inhibitor, we studied the role of the blood vessels in the dentition of...

journal_title：Journal of dental research

authors： Crucke J,Huysseune A

更新日期：2015-01-01 00:00:00

abstract：:In this study, we investigated whether selective activation of nociceptive primary afferent fibers by capsaicin would induce modulations on tooth-pulp-evoked sensory or inhibitory masseter reflex responses in healthy human subjects. The contribution of central N-methyl-D-aspartate (NMDA) receptor mechanisms in capsaic...

journal_title：Journal of dental research

authors： Kemppainen P,Waltimo A,Waltimo T,Könönen M,Pertovaara A

更新日期：1997-09-01 00:00:00

abstract：:The type of attachment that is used in oral rehabilitation by means of implant-retained mandibular overdentures may influence the retention and the stability of the denture. In this study, we examined the hypothesis that a better retention and stability of the denture improve the oral function. Eighteen edentulous sub...

journal_title：Journal of dental research

authors： van Kampen FM,van der Bilt A,Cune MS,Bosman F

更新日期：2002-03-01 00:00:00

abstract：:Periodontal ligament (PDL) cells play an important role in maintaining the homeostasis of periodontal tissues. However, it is not known how PDL cells contribute to osteoclastogenesis. In this study, we examined the consequences of cell-to-cell interactions between peripheral blood mononuclear cells (PBMCs) and PDL cel...

journal_title：Journal of dental research

authors： Kanzaki H,Chiba M,Shimizu Y,Mitani H

更新日期：2001-03-01 00:00:00

abstract：:A series of 4,6-dichloro-1,3,5-triazines [e.g., 2-allylamino-(ADT), diallylamino-(DADT), 2-N-p-allyloxyphenylamino-, 2-N-allyl-N-phenylamino-, and 2-N-allyl-N-p-tolylamino-4,6-dichloro-1,3,5-triazine] was synthesized and characterized by IR, NMR, and mass spectrometry. These monomers have chlorine atoms that can react...

journal_title：Journal of dental research

authors： Lee CH,Liu XQ,Gong XQ

更新日期：1986-12-01 00:00:00

abstract：:Obesity is a widespread chronic inflammatory disorder characterized by an increased overall disease burden and significant association with periodontitis. The aim of this prospective clinical cohort study was to investigate the effect of obesity on orthodontic tooth movement. Fifty-five adolescent patients (27 males, ...

journal_title：Journal of dental research

authors： Saloom HF,Papageorgiou SN,Carpenter GH,Cobourne MT

更新日期：2017-05-01 00:00:00

abstract：:The surface enamel of fetal bovine teeth was stained with GBHA to indicate the position of bands of smooth-ended and ruffle-ended ameloblasts relative to the developing enamel. The boundaries of the bands were scored, under a dissecting microscope, and the bulk enamel under each band was collected. The enamel samples ...

journal_title：Journal of dental research

authors： Bawden JW,Keels MA,Deaton TG,Crenshaw MA

更新日期：1988-06-01 00:00:00

abstract：:Although the contribution of the oral microbiota to oral malodor is well-documented, the potential role of Gram-positive micro-organisms is unclear. In the current study, we tested the hypothesis that Gram-positive micro-organisms contribute to malodor production by deglycosylating oral glycoproteins, rendering them s...

journal_title：Journal of dental research

authors： Sterer N,Rosenberg M

更新日期：2006-10-01 00:00:00

abstract：:Previous studies showed that residual compressive stresses induced by thermal tempering retarded the growth of surface cracks in bilayered porcelain disks. The objectives of the present study were: (1) to determine whether thermal tempering by air blasting reduces the length of cracks induced by microhardness indentat...

journal_title：Journal of dental research

authors： DeHoff PH,Anusavice KJ,Vontivillu SB

更新日期：1996-02-01 00:00:00

abstract：:Application of an incisal bite plane for as little as three d caused a significant increase in the size of the sublingual glands of rats, with some evidence of hyperplasia and hypertrophy of the acinar cells. The enlargement had few effects on salivary secretion, and the gland changes were reversible. ...

journal_title：Journal of dental research

authors： Hioki S,Niwa K,Kishimoto T,Kawazoe T,Yokota Y,Abe K,Dawes C

更新日期：1983-06-01 00:00:00

abstract：:Defined sets of transcriptional factors can reprogram human somatic cells to induced pluripotent stem (iPS) cells. However, many types of human cells are not easily accessible to minimally invasive procedures. Here we evaluated dental pulp cells (DPCs) as an optimal source of iPS cells, since they are easily obtained ...

journal_title：Journal of dental research

authors： Tamaoki N,Takahashi K,Tanaka T,Ichisaka T,Aoki H,Takeda-Kawaguchi T,Iida K,Kunisada T,Shibata T,Yamanaka S,Tezuka K

更新日期：2010-08-01 00:00:00

abstract：:Laser-Raman spectra of synthetic apatites containing from zero to 12.4 wt% carbonate ions and enamel apatite are reported. Special attention is paid to the correlation between the intensities of the carbonate, phosphate, and hydroxyl modes and the carbonate content in the apatites. The data presented here indicate tha...

journal_title：Journal of dental research

authors： Nishino M,Yamashita S,Aoba T,Okazaki M,Moriwaki Y

更新日期：1981-03-01 00:00:00

abstract：:In cases of pulp exposure due to deep dental caries or severe traumatic injuries, existing pulp-capping materials have a limited ability to reconstruct dentin-pulp complexes and can result in pulpectomy because of their low potentials to accelerate dental pulp cell activities, such as migration, proliferation, and dif...

journal_title：Journal of dental research

authors： Yoshida S,Wada N,Hasegawa D,Miyaji H,Mitarai H,Tomokiyo A,Hamano S,Maeda H

更新日期：2016-10-01 00:00:00

abstract：:The etiology and pathogenesis of craniofacial birth defects are multifactorial and include both genetic and environmental factors. Despite the identification of numerous genes associated with congenital craniofacial anomalies, our understanding of their etiology remains incomplete, and many affected individuals have a...

journal_title：Journal of dental research

authors： Dash S,Bhatt S,Falcon KT,Sandell LL,Trainor PA

更新日期：2020-11-06 00:00:00

abstract：:The relative contribution of the matrix of dentin to the physical properties of dentin is unknown but thought to be small. The objective of this study was to test the hypothesis that the demineralized matrix of dentin contributes little to the strength of dentin by measuring and comparing the ultimate tensile strength...

journal_title：Journal of dental research

authors： Sano H,Ciucchi B,Matthews WG,Pashley DH

更新日期：1994-06-01 00:00:00

abstract：:The effects of various additives on the setting of the glass-ionomer cement system was studied by means of cone and plate viscometry. The action of (+)-tartaric acid, the most important additive, on the setting reaction depended on its concentration. Low concentrations accelerated the development of viscosity of the c...

journal_title：Journal of dental research

authors： Hill RG,Wilson AD

更新日期：1988-12-01 00:00:00

abstract：:The microstructure of the set glass-polyalkenoate cement has not been undertaken beyond a study where an Electron Probe Micro Analyser was used. The purpose of this investigation was to determine the ion distribution in matrix parts of the set cement by means of Secondary Ion Mass Spectrometry (SIMS). Among the techni...

journal_title：Journal of dental research

authors： Maeda T,Mukaeda K,Shimohira T,Katsuyama S

更新日期：1999-01-01 00:00:00

abstract：:The effects of Escherichia coli endotoxin upon mouse L929 cell proliferation, DNA synthesis, protein synthesis, and proline incorporation were determined. It was found that a level of endotoxin which inhibited cell proliferation prompted a similar inhibition of DNA synthesis and overall cell protein synthesis. In cont...

journal_title：Journal of dental research

authors： Singer RE,Dutton WG

更新日期：1979-06-01 00:00:00

abstract：:Much research has been devoted to the study of etched enamel, since it is critical to bonding. Currently, there are no precise data regarding the etched-enamel specific surface area. The aim of this study was to characterize, by two different methods, the surface of human dental enamel in vitro after being etched. It ...

journal_title：Journal of dental research

authors： Orellana MF,Nelson AE,Carey JP,Heo G,Boychuk DG,Major PW

更新日期：2008-06-01 00:00:00