Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition.

abstract：:In mineralizing hamster molars, the influence of several inhibitors on p-NPP-ase has been demonstrated, and compared with their effect on PPi-ase, known to belong to the same enzyme. Whereas the latter activity is much more physiological, p-NPP is a better substrate to distinguish between the effects of bivalent catio...

journal_title：Journal of dental research

authors： Wöltgens JH

更新日期：1977-10-01 00:00:00

abstract：:Periodontitis is a chronic inflammatory disease induced by a biofilm that forms on the tooth surface. Increased periodontal disease is associated with aging. We investigated the effect of aging on challenge by oral pathogens, examining the host response, colonization, and osteoclast numbers in aged versus young mice. ...

journal_title：Journal of dental research

authors： Wu Y,Dong G,Xiao W,Xiao E,Miao F,Syverson A,Missaghian N,Vafa R,Cabrera-Ortega AA,Rossa C Jr,Graves DT

更新日期：2016-04-01 00:00:00

abstract：:Occlusal alterations may result in changes in the functional performance of masticatory muscles. In this study, we set up an experimental model in rats to examine whether masticatory muscle abnormalities occur after a malocclusion is induced. Rats underwent unilateral amputation of the molar cusps to simulate an occlu...

journal_title：Journal of dental research

authors： Bani D,Bani T,Bergamini M

更新日期：1999-11-01 00:00:00

abstract：:This study indicated that a clear relationship exists between silicon and fluoride. We have also demonstrated a probable surface enamel silicon effect that increases fluoride uptake. The complex set of relationships described in the surface chemistry of calcium, tin, and zirconium with fluoride, hydroxide, phosphate, ...

journal_title：Journal of dental research

authors： Levy JS,Koritzer RT

更新日期：1976-09-01 00:00:00

abstract：:Dental diseases are now viewed as a consequence of a deleterious shift in the balance of the normally stable resident oral microbiome. It is known that frequent carbohydrate consumption or reduced saliva flow can lead to caries, and excessive plaque accumulation increases the risk of periodontal diseases. However, whe...

journal_title：Journal of dental research

authors： Rosier BT,Marsh PD,Mira A

更新日期：2018-04-01 00:00:00

abstract：:In periodontal surgery, healing after guided tissue regeneration (GTR) may be explained by differences in functional activities of gingival and periodontal ligament fibroblasts (GF and PDLF). Several studies in vitro have supported this hypothesis, but much remains to be defined. In the present work, gingival and peri...

journal_title：Journal of dental research

authors： Giannopoulou C,Cimasoni G

更新日期：1996-03-01 00:00:00

abstract：:Pulpal blood flow was determined in 32 dogs ranging in age from 6 weeks to 18 months by the isotope fractionation method incorporating diffusible and nondiffusible tracers. Dogs were placed into selected age groups by the developmental status of the canine teeth. For the teeth sampled, the maxillary first, second, and...

journal_title：Journal of dental research

authors： Path MG,Meyer MW

更新日期：1977-10-01 00:00:00

abstract：:In two separate experiments, none of the 14 subunits examined consistently ranked dentifrices similarly to the ranking obtained when the individual rat was used as the experimental unit. Arbitrarily dividing the rat into subunits and then comparing results among these subunits may lead to false conclusions since the r...

journal_title：Journal of dental research

authors： Briner WW

更新日期：1976-05-01 00:00:00

abstract：:The complexity of the periodontal microbiota resembles that of the gastro-intestinal tract, where infectious diseases are treatable via probiotics. In the oropharyngeal region, probiotic or replacement therapies have shown some benefit in the prevention of dental caries, otitis media, and pharyngitis, but their effect...

journal_title：Journal of dental research

authors： Teughels W,Newman MG,Coucke W,Haffajee AD,Van Der Mei HC,Haake SK,Schepers E,Cassiman JJ,Van Eldere J,van Steenberghe D,Quirynen M

更新日期：2007-11-01 00:00:00

abstract：:The monomer triethyleneglycoldimethacrylate (TEGDMA) is used as a diluent in many resin-based dental materials. It was previously shown in vitro that TEGDMA was released into the adjacent biophase from such materials during the first days after placement. In this study, the uptake, distribution, and excretion of 14C-T...

journal_title：Journal of dental research

authors： Reichl FX,Durner J,Hickel R,Kunzelmann KH,Jewett A,Wang MY,Spahl W,Kreppel H,Moes GW,Kehe K,Walther U,Forth W,Hume WR

更新日期：2001-05-01 00:00:00

abstract：:Using a hydraulic bellows system mounted on a maxillary partial denture, continuous force-displacement data were taken in an edentulous area in the maxillary bicuspid-molar region on ten adults. Both loading and unloading force-displacement curves showed three segments. Two visco-elastic properties - hysteresis and re...

journal_title：Journal of dental research

authors： Ho TP,Weinstein S,Bowley WW

更新日期：1984-10-01 00:00:00

abstract：:Bone and dentin share similar biochemical compositions and physiological properties. Dentin, a major tooth component, is formed by odontoblasts; in contrast, bone is produced by osteoblasts. Osterix (Osx), a zinc finger-containing transcription factor, has been identified as an essential regulator of osteoblast differ...

journal_title：Journal of dental research

authors： Kim TH,Bae CH,Lee JC,Kim JE,Yang X,de Crombrugghe B,Cho ES

更新日期：2015-03-01 00:00:00

abstract：:Monolayers of feline parotid acinar cells were infected with feline rhinotracheitis herpes virus. Membrane potentials and input resistances were measured before and during infection. Uninfected acinar cells had an average membrane potential of -51 mV and resistances from 6 to 120 mega-ohms; cells infected for more tha...

journal_title：Journal of dental research

authors： Weigel RJ,Fritz ME,Nahmias AJ

更新日期：1981-12-01 00:00:00

abstract：:Although a secular decline is being seen in coronal caries in children in industrialized countries, there appears to be a relatively high prevalence of root caries, with chronologically older adults exhibiting the highest prevalences. This paper reviews the descriptive and analytical epidemiology of root caries as fou...

journal_title：Journal of dental research

authors： Beck J

更新日期：1990-05-01 00:00:00

abstract：:The effects of substituting gluconate for extracellular Cl, and of treatment with various ion transport blockers, on cytosol pH (pHi) and secretion by the acetylcholine stimulated rat mandibular gland were studied in vitro. Gluconate replacement increased pHi from 7.12 +/- 0.02 to 7.27 +/- 0.04, caused secretory rate ...

journal_title：Journal of dental research

authors： Young JA,Cook DI,Evans LA,Pirani D

更新日期：1987-02-01 00:00:00

abstract：:Periodontitis is a chronic infectious disease driven by dysbiosis, an imbalance between commensal bacteria and the host organism. Periodontitis is a leading cause of tooth loss in adults and occurs in about 50% of the US population. In addition to the clinical challenges associated with treating periodontitis, the pro...

journal_title：Journal of dental research

authors： Martins MD,Jiao Y,Larsson L,Almeida LO,Garaicoa-Pazmino C,Le JM,Squarize CH,Inohara N,Giannobile WV,Castilho RM

更新日期：2016-02-01 00:00:00

abstract：:A number of studies have been made investigating the properties of dental prosthodontic soft polymer materials. In such materials, which are used as short-term denture soft liners, the polymer component is complexed with one or more plasticizers. This lowers the glass transition temperature, Tg, of the polymer by allo...

journal_title：Journal of dental research

authors： Jones DW,Hall GC,Sutow EJ,Langman MF,Robertson KN

更新日期：1991-05-01 00:00:00

abstract：:The incorporation of polymerizable cationic monomers has been attempted to generate dental resinous materials with antibacterial activity. This study tested the hypothesis that a dental adhesive containing a cationic monomer, methacryloxylethyl cetyl dimethyl ammonium chloride (DMAE-CB), would influence biofilm format...

journal_title：Journal of dental research

authors： Li F,Chai ZG,Sun MN,Wang F,Ma S,Zhang L,Fang M,Chen JH

更新日期：2009-04-01 00:00:00

abstract：:Van der Woude syndrome (VWS) is an autosomal-dominant oral facial disorder. To find a gene mutation in a Japanese family using fingernail DNA samples, we performed this study. We hypothesized that a gene mutation in IRF6 might be involved in VWS, and that fingernail DNA samples may be valuable for detecting such mutat...

journal_title：Journal of dental research

authors： Matsuzawa N,Shimozato K,Natsume N,Niikawa N,Yoshiura K

更新日期：2006-12-01 00:00:00

abstract：:The biochemical function, adenylate energy charge (AEC), correlates with the viable count of S. mutans. AEC may be used to estimate the percent viable fraction of bacteria in dental plaque samples. An interactive computer program designed to process the AEC data is described. ...

journal_title：Journal of dental research

authors： Kemp CW

更新日期：1979-11-01 00:00:00

abstract：:The surface enamel of fetal bovine teeth was stained with GBHA to indicate the position of bands of smooth-ended and ruffle-ended ameloblasts relative to the developing enamel. The boundaries of the bands were scored, under a dissecting microscope, and the bulk enamel under each band was collected. The enamel samples ...

journal_title：Journal of dental research

authors： Bawden JW,Keels MA,Deaton TG,Crenshaw MA

更新日期：1988-06-01 00:00:00

abstract：:Local administrations of prostaglandins E1 or E2 combined with orthodontic tooth movement can approximately double the rate of tooth movement in monkeys compared to that of the control. Macroscopically, no side-effect was observed in the gingiva and associated structures. ...

journal_title：Journal of dental research

authors： Yamasaki K,Shibata Y,Fukuhara T

更新日期：1982-12-01 00:00:00

abstract：:Sense of coherence (SOC) has been related to oral health behaviors and oral-health-related quality of life (OHRQoL) in observational studies. This cluster-randomized trial aimed to test the effect of an intervention to enhance SOC on OHRQoL in children. Twelve primary schools were randomly allocated to intervention an...

journal_title：Journal of dental research

authors： Nammontri O,Robinson PG,Baker SR

更新日期：2013-01-01 00:00:00

abstract：:With clinical oral examinations not always possible in health surveys, researchers may instead be invited to add questions to a wider health survey. In such situations, an item is needed which adequately represents both clinical and self-reported oral health. This study investigated the clinical validity of Locker's g...

journal_title：Journal of dental research

authors： Thomson WM,Mejia GC,Broadbent JM,Poulton R

更新日期：2012-11-01 00:00:00

abstract：:The Global Burden of Disease (GBD) 2010 Study produced comparable estimates of the burden of 291 diseases and injuries in 1990, 2005, and 2010. This article reports on the global burden of untreated caries, severe periodontitis, and severe tooth loss in 2010 and compares those figures with new estimates for 1990. We u...

journal_title：Journal of dental research

authors： Marcenes W,Kassebaum NJ,Bernabé E,Flaxman A,Naghavi M,Lopez A,Murray CJ

更新日期：2013-07-01 00:00:00

abstract：:A multiple logistic regression analysis was used to compute the odds ratios for 11 common occlusal features for asymptomatic controls (n = 147) vs. five temporomandibular disorder groups: Disc Displacement with Reduction (n = 81), Disc Displacement without Reduction (n = 48), Osteoarthrosis with Disc Displacement Hist...

journal_title：Journal of dental research

authors： Pullinger AG,Seligman DA,Gornbein JA

更新日期：1993-06-01 00:00:00

abstract：:An intra-oral model system has been developed which uses a single-section technique for before-and-after measurements on the same tissue. This model allows for placement of sections of enamel at both buccal and approximal sites. These sections may be sound or possess white-spot lesions. This allows for the evaluation ...

journal_title：Journal of dental research

authors： Wefel JS,Maharry GJ,Jensen ME,Harless JD

更新日期：1987-09-01 00:00:00

abstract：:Although the tripeptides Glu-O-Phosphoserine-Tyr and Glu-O-Phosphoserine-Leu have been identified in embryonic bovine enamel proteins, 1, 2 the issue of whether both sequences occur in each of the phosphopeptides, or whether certain sequences occur in specific peptides only, has recently been resolved by isolating hom...

journal_title：Journal of dental research

authors： Glimcher MJ

更新日期：1979-03-01 00:00:00

abstract：:Tritiated proline was administered to domestic cats during the development of their permanent dentition. The amount of residual radioactivity was determined autoradiographically at various times after cavity preparation in mature molars and premolars. Two wk after cavity preparation, the amount of radiolabel beneath t...

journal_title：Journal of dental research

authors： Hoppenbrouwers PM,Borggreven JM,Thé GS,Maltha JC

更新日期：1982-09-01 00:00:00

abstract：:The acquired enamel pellicle is an oral, fluid-derived protein layer that forms on the tooth surface. It is a biologically and clinically important integument that protects teeth against enamel demineralization, and abrasion. Tooth surfaces are exposed to different proteinaceous microenvironments depending on the enam...

journal_title：Journal of dental research

authors： Heller D,Helmerhorst EJ,Oppenheim FG

更新日期：2017-04-01 00:00:00