Abstract:
:The complexity of the periodontal microbiota resembles that of the gastro-intestinal tract, where infectious diseases are treatable via probiotics. In the oropharyngeal region, probiotic or replacement therapies have shown some benefit in the prevention of dental caries, otitis media, and pharyngitis, but their effectiveness in the treatment of periodontitis is unknown. Therefore, this study addressed the hypothesis that the application of selected beneficial bacteria, as an adjunct to scaling and root planing, would inhibit the periodontopathogen recolonization of periodontal pockets. Analysis of the data showed, in a beagle dog model, that when beneficial bacteria were applied in periodontal pockets adjunctively after root planing, subgingival recolonization of periodontopathogens was delayed and reduced, as was the degree of inflammation, at a clinically significant level. The study confirmed the hypothesis and provides a proof of concept for a guided pocket recolonization (GPR) approach in the treatment of periodontitis.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Teughels W,Newman MG,Coucke W,Haffajee AD,Van Der Mei HC,Haake SK,Schepers E,Cassiman JJ,Van Eldere J,van Steenberghe D,Quirynen Mdoi
10.1177/154405910708601111subject
Has Abstractpub_date
2007-11-01 00:00:00pages
1078-82issue
11eissn
0022-0345issn
1544-0591pii
86/11/1078journal_volume
86pub_type
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