Abstract:
:Lysozyme concentration was quantitated immunochemically in parotid and submandibular-sublingual saliva of 46 caries-resistant and 17 caries-susceptible adults. There was essentially no difference between the two groups. The concentration of lysozyme was three times higher in the submandibular-sublingual than in the parotid secretion, and was significantly higher in unstimulated submandibular saliva than in secretions stimulated with 1, 2, or 4% citric acid. There were no significant differences in flow rate between caries-resistant and -susceptible subjects. Salivary lysozyme concentration is not a critical determinant of resistance or susceptibility to caries.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Stuchell RN,Mandel IDdoi
10.1177/00220345830620050701subject
Has Abstractpub_date
1983-05-01 00:00:00pages
552-4issue
5eissn
0022-0345issn
1544-0591journal_volume
62pub_type
杂志文章abstract::It is shown that the creep behavior of a commercial dispersant-amalgam containing copper is improved by the addition of a manganese-containing alloy. This improvement is apparently obtained without any serious changes in corrosion resistance, provided that no more than 20% of the Mn alloy is added. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345780570090601
更新日期:1978-09-01 00:00:00
abstract::Relative glycogen synthetic abilities of resting cells of fresh clinical isolates of Actinomyces viscosus and Actinomyces naeslundii originating from dental plaque samples over root surface caries lesions and non-carious sites were studied under anaerobic conditions at a constant pH of 7.0, with U-(14C)-glucose used a...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650060701
更新日期:1986-06-01 00:00:00
abstract::The periodontium contains heterogeneous mesenchymal cell populations with various differentiation potentials. The capacity of these cells for tissue formation as well as the origin of their precursors are still not entirely defined. In this study, cells originating from different periodontal tissues were cultured in v...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345950740051201
更新日期:1995-05-01 00:00:00
abstract::The effect of different doses of polyadenylic and polyuridylic acids (poly A:U) was studied in control rats and in rats exposed to hypoxia. In the control rats, administration of different doses of poly A:U did not change the thickness of the epiphyseal plate or increase the incorporation of 3H-phenylalanine as judged...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550041701
更新日期:1976-07-01 00:00:00
abstract::The objective of this study was to determine the in vitro corrosion products that resulted from crevice corrosion of low- and high-copper dental amalgams. Specimens were potentiostatically polarized in a chloride-containing electrolyte while set against a PTFE surface to form a crevice. After 16 h, corrosion products ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345910700071301
更新日期:1991-07-01 00:00:00
abstract::We evaluated the histopathological response of the periodontal membrane to intentionally-replanted teeth carrying composite (experimental) and silver amalgam (control) restorations in the middle third of each root. The study revealed that the amalgam produced, in the periodontal tissues, an initial localized inflammat...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620011801
更新日期:1983-01-01 00:00:00
abstract::Antimicrobial agents, delivered either by mouthrinse or toothpaste, can be used to maintain plaque at levels compatible with oral health by (a) reducing existing plaque, (b) preventing the formation of new plaque, (c) selectively inhibiting those particular bacteria that are associated with disease, and (d) inhibiting...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345920710071501
更新日期:1992-07-01 00:00:00
abstract::Tooth agenesis is one of the most common developmental anomalies affecting function and esthetics. The paired-domain transcription factor, Pax9, is critical for patterning and morphogenesis of tooth and taste buds. Mutations of PAX9 have been identified in patients with tooth agenesis. Despite significant progress in ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034517729322
更新日期:2018-02-01 00:00:00
abstract::Mutations in ALPL result in hypophosphatasia (HPP), a disease causing defective skeletal mineralization. ALPL encodes tissue nonspecific alkaline phosphatase (ALP), an enzyme that promotes mineralization by reducing inorganic pyrophosphate, a mineralization inhibitor. In addition to skeletal defects, HPP causes dental...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515573273
更新日期:2015-05-01 00:00:00
abstract::Improved mechanical properties of resin composites have been reported to be a consequence of the addition of aldehyde to the resins. The objective of the present study was to examine whether this improvement could be attributed to an increased degree of conversion of double bonds. For this purpose, propanal was added ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345940730101101
更新日期:1994-10-01 00:00:00
abstract::Minimizing patient exposure while maintaining a diagnostically acceptable radiograph is a major goal in diagnostic radiography. Rare-earth filters may be the means to achieve this goal due to their "band-pass effect". The purpose of this study was to examine the image contrast effects and exposure reductions for vario...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660080701
更新日期:1987-08-01 00:00:00
abstract::Artificial white spot lesions have been prepared on bovine enamel surfaces by the controlled addition of lactate buffer containing methylhydroxydiphosphonate ions. The rates of remineralization have been measured using a constant composition method in solutions of calcium phosphate of low supersaturation. Deposition o...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630061001
更新日期:1984-06-01 00:00:00
abstract::Lactoferrin is one of a number of multifunctional proteins that are present in or on all mucosal surfaces throughout the body. Levels of lactoferrin are consistently elevated in inflammatory diseases such as arthritis, inflammatory bowel diseases, corneal disease, and periodontitis. Single-nucleotide polymorphisms (SN...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034515577413
更新日期:2015-06-01 00:00:00
abstract::Three strain combinations of in-bred mice representing strong and moderate histocompatibility barriers were used to determine if tooth allotransplants evoked strong or weak immunologic memory as measured by the second-set donor-strain skin graft technique. At issue was whether the anatomic site of engraftment could in...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630010901
更新日期:1984-01-01 00:00:00
abstract::Rat parotid secretory granule membranes were examined for the presence of calcium-dependent protein kinase activities and kinase substrates. Protein kinase C (C-kinase), which is stimulated by certain phospholipids, was present in the membranes, as indicated by its ability to catalyze the phosphorylation of histone. T...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660022901
更新日期:1987-02-01 00:00:00
abstract::A gravity sintering fabrication technique has been developed for producing Co-Cr-Mo alloy dental implants having a porous coating on the root portion. This process allows for control of pore structure enabling ingrowth of either bone or fibrous tissue. The microstructure and mechanical properties of these materials ha...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560050501
更新日期:1977-05-01 00:00:00
abstract::Dental diseases are now viewed as a consequence of a deleterious shift in the balance of the normally stable resident oral microbiome. It is known that frequent carbohydrate consumption or reduced saliva flow can lead to caries, and excessive plaque accumulation increases the risk of periodontal diseases. However, whe...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034517742139
更新日期:2018-04-01 00:00:00
abstract::The whisker pad area (WP) is innervated by the second branch of the trigeminal nerve and experiences allodynia and hyperalgesia following transection of the mental nerve (MN; the third branch of the trigeminal nerve). However, the mechanisms of this extra-territorial pain remain unclear. The ionotropic P2X(7) ATP rece...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034512474668
更新日期:2013-03-01 00:00:00
abstract::Periodontitis is a complex, multifactorial chronic disease involving continuous interactions among bacteria, host immune/inflammatory responses, and modifying genetic and environmental factors. More than any other cytokine family, the interleukin (IL)-1 family includes key signaling molecules that trigger and perpetua...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520945209
更新日期:2020-12-01 00:00:00
abstract::Although a secular decline is being seen in coronal caries in children in industrialized countries, there appears to be a relatively high prevalence of root caries, with chronologically older adults exhibiting the highest prevalences. This paper reviews the descriptive and analytical epidemiology of root caries as fou...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345900690051901
更新日期:1990-05-01 00:00:00
abstract::The uptake patterns of 90Sr in developing rat molar enamel were studied in vivo and in vitro. Autoradiographic methods were used that preclude loss or translocation of tracers associated with water-soluble compounds in the sections. In eight-day-old rats injected with the tracer, 90Sr uptake in the enamel was signific...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590121301
更新日期:1980-12-01 00:00:00
abstract::During the 18th century, France was the leader in the field of dentistry, exemplified by Pierre Fauchard (1678-1761), who was given the title "the father of modern dentistry" for his comprehensive work, Le Chirurgien Dentiste. This paper examines an 18th century dental treatment in a barely 50-year-old male whose body...
journal_title:Journal of dental research
pub_type: 历史文章,杂志文章
doi:10.1177/0022034508329872
更新日期:2009-03-01 00:00:00
abstract::As a major intracellular degradation and recycling machinery, autophagy plays an important role in maintaining cellular homeostasis and remodeling during normal development. Our previous study showed that fluorapatite (FA) crystal-coated electrospun polycaprolactone (PCL) was capable of inducing differentiation and mi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516636852
更新日期:2016-06-01 00:00:00
abstract::Weanling rice rats were fed either standard laboratory chow or Diet 2000. The animals were sacrificed at 4, 8, 12, and 15 weeks. There was an increasing amount of exposed root surface and root surface caries with age in the animals fed Diet 2000. There was exposed root surface but no caries in the animals fed laborato...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560091701
更新日期:1977-09-01 00:00:00
abstract::As an approach for improving the outcome and predictability of periodontal regenerative therapies, we have focused on determining the responses of cells within the local environment to putative regenerative factors. This study examined the effects of bone morphogenetic protein-2 (BMP-2) on murine cementoblasts in vitr...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200106
更新日期:2003-01-01 00:00:00
abstract::Priming with tumor antigens is one of the most important strategies in cancer immunotherapy. To enhance tumor antigenicity, OK-432, a streptococcal preparation, was coupled to squamous cell carcinoma (KLN-205) by means of a 0.2% glutaraldehyde method. The purpose of this study was to investigate whether OK-432-conjuga...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200813
更新日期:2003-08-01 00:00:00
abstract::Although pulp fibroblasts are a major cell type in dental pulp, their roles in microbial recognition and pulpal inflammation are not well-understood. Considering the pivotal role of Toll-like receptors (TLRs) in the recognition of micro-organisms, we hypothesized that TLRs on pulp fibroblasts may induce inflammatory s...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509354720
更新日期:2010-02-01 00:00:00
abstract::Hereditary diseases affecting the skeleton are heterogeneous in etiology and severity. Though many of these conditions are individually rare, the total number of people affected is great. These disorders often include dental-oral-craniofacial (DOC) manifestations, but the combination of the rarity and lack of in-depth...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034514529150
更新日期:2014-07-01 00:00:00
abstract::The effect of inflammation on the distribution of chondroitin sulfate and dermatan sulfate proteoglycans was assessed after normal and inflamed human gingivae were stained with monoclonal antibodies against these extracellular matrix macromolecules. The tissues were obtained following periodontal surgery and reacted w...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345920710090801
更新日期:1992-09-01 00:00:00
abstract::There is a large variability between and among individuals in the physiology of mastication, but it is not known whether this produces a similar variability in the particle sizes of food boluses at the end of the chewing process. Food boluses obtained just before swallowing were analyzed in ten subjects (aged 36.7 +/-...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/154405910408300713
更新日期:2004-07-01 00:00:00