Abstract：
:The aim of this meta-analysis, based on individual participant data from several studies, was to investigate the influence of patient-, materials-, and tooth-related variables on the survival of posterior resin composite restorations. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we conducted a search resulting in 12 longitudinal studies of direct posterior resin composite restorations with at least 5 years' follow-up. Original datasets were still available, including placement/failure/censoring of restorations, restored surfaces, materials used, reasons for clinical failure, and caries-risk status. A database including all restorations was constructed, and a multivariate Cox regression method was used to analyze variables of interest [patient (age; gender; caries-risk status), jaw (upper; lower), number of restored surfaces, resin composite and adhesive materials, and use of glass-ionomer cement as base/liner (present or absent)]. The hazard ratios with respective 95% confidence intervals were determined, and annual failure rates were calculated for subgroups. Of all restorations, 2,816 (2,585 Class II and 231 Class I) were included in the analysis, of which 569 failed during the observation period. Main reasons for failure were caries and fracture. The regression analyses showed a significantly higher risk of failure for restorations in high-caries-risk individuals and those with a higher number of restored surfaces.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Opdam NJ,van de Sande FH,Bronkhorst E,Cenci MS,Bottenberg P,Pallesen U,Gaengler P,Lindberg A,Huysmans MC,van Dijken JWdoi
10.1177/0022034514544217subject
Has Abstractpub_date
2014-10-01 00:00:00pages
943-9issue
10eissn
0022-0345issn
1544-0591pii
0022034514544217journal_volume
93pub_type
杂志文章,meta分析,评审abstract：:Cultures of Streptococcus mutans MFe28 (serotype h) were grown with differing extracellular polysaccharide (EPS) content. Biochemical and physicochemical characteristics considered relevant to caries were measured. Acid production parameters measured in a pH-stat were: Vm = 0.76 +/- 0.14 mumol/g/sec (wet weight); appa...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345880670060101
更新日期：1988-06-01 00:00:00
abstract：:Lipopolysaccharide (LPS) has been shown to be a prominent pathogenic factor in inflammatory bone loss. However, knowledge of the mechanisms involved is limited. The role of the SDF-1/CXCR4 (Stromal-derived factor-1 and its unique chemokine receptor) axis in LPS-induced bone loss has not been studied. The aim of this s...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510379019
更新日期：2011-02-01 00:00:00
abstract：:Much research has been devoted to the study of etched enamel, since it is critical to bonding. Currently, there are no precise data regarding the etched-enamel specific surface area. The aim of this study was to characterize, by two different methods, the surface of human dental enamel in vitro after being etched. It ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910808700607
更新日期：2008-06-01 00:00:00
abstract：:The incisor dentin of hypophosphatemic (Hyp) mice was examined histopathologically to determine whether the multiple occurrences of interglobular dentin would be influenced by the serum phosphate level. Both normal and Hyp mice (12 weeks of age) were divided into two groups. The mice in one group were given a control ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345920710031101
更新日期：1992-03-01 00:00:00
abstract：:Cardiovascular disease is a common cause of morbidity and premature mortality. Cardiovascular disease can be prevented when risk factors are identified early. Calcified carotid artery atheromas (CCAAs), detected in panoramic radiographs, and periodontitis have both been associated with increased risk of cardiovascular...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034519885362
更新日期：2020-01-01 00:00:00
abstract：:The reaction of the microvasculature in the periodontal ligament to mechanical pressure is considered a very important phenomenon with respect to the biological background to orthodontic tooth movement. For clarification of the microvascular reaction to mechanical pressure, an experimental model that incorporated a ha...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345920710060701
更新日期：1992-06-01 00:00:00
abstract：:Enamel fluorosis can occur following either an acute or chronic exposure to fluoride during tooth formation. Fluorosed enamel is characterized by a retention of amelogenins in the early-maturation stage, and by the formation of a more porous enamel with a subsurface hypomineralization. The mechanisms by which fluoride...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/00220345920710051701
更新日期：1992-05-01 00:00:00
abstract：:Inorganic polyphosphate [Poly(P)] is especially prevalent in osteoblasts. We tested the hypothesis that Poly(P) stimulates osteoblastic differentiation and polyphosphate metabolism for bone formation. The osteoblast-like cell line, MC 3T3-E1, was cultured with Poly(P), and gene expression was evaluated by real-time re...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510363096
更新日期：2010-05-01 00:00:00
abstract：:The goal of this study was to assess the ability of a scintillation camera method to detect areas of active bone loss due to periodontitis. Technetium 99m methylene diphosphonate was used as the bone-seeking radiopharmaceutical. Bone-seeking radiopharmaceutical uptake (BSRU) was imaged and quantified in alveolar bone ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345910700010801
更新日期：1991-01-01 00:00:00
abstract：:This study was undertaken in order to correlate the immune status of persons with various types of immune dysfunctions with the incidence of dental caries. Preliminary data on caries experience and the microbial composition of plaque in these individuals are presented. The findings suggest that persons with immunoglob...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560030201
更新日期：1977-03-01 00:00:00
abstract：:Purinergic signaling is involved in pain generation and modulation in the nociceptive sensory nervous system. Adenosine triphosphate (ATP) induces pain via activation of ionotropic P2X receptors while adenosine mediates analgesia via activation of metabotropic P1 receptors. These purinergic signaling are determined by...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034517692953
更新日期：2017-06-01 00:00:00
abstract：:Better understanding of dental caries and other oral conditions has guided new strategies to prevent disease and manage its consequences at individual and public health levels. This article discusses advances in prevention and minimal intervention dentistry over the last century by focusing on some milestones within s...
journal_title：Journal of dental research
pub_type： 历史文章,杂志文章
doi：10.1177/0022034519837252
更新日期：2019-06-01 00:00:00
abstract：:The objective of this study was to assess the relative effects of age and oral hygiene on the progression of periodontitis by estimating incidence from age-specific prevalence. This study analyzed data from a representative national sample of 14,690 dentate Americans, aged from 15 to 74, seen in the first National Hea...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345870660010201
更新日期：1987-01-01 00:00:00
abstract：:Relative glycogen synthetic abilities of resting cells of fresh clinical isolates of Actinomyces viscosus and Actinomyces naeslundii originating from dental plaque samples over root surface caries lesions and non-carious sites were studied under anaerobic conditions at a constant pH of 7.0, with U-(14C)-glucose used a...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650060701
更新日期：1986-06-01 00:00:00
abstract：:The initiator of calculus matrix calcification, in vitro, was isolated. Crude phospholipid, known to contain the factor, was separated into five fractions by column chromatography. A single protein-containing fraction induced apatite formation during incubation. The nucleating fraction was indentified as a proteolipid...
journal_title：Journal of dental research
pub_type： 历史文章,杂志文章
doi：10.1177/00220345770560020701
更新日期：1977-02-01 00:00:00
abstract：:IL-18 is a pro-inflammatory cytokine that is important in the regulation of T-cells and is elevated in inflammatory disorders such as periodontal disease. Vasoactive intestinal peptide (VIP) modulates immune responses to the periodontal pathogen Porphyromonas gingivalis (Pg). Our objective was to investigate the effec...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910708600915
更新日期：2007-09-01 00:00:00
abstract：:The composition of the degradable glasses used in commercial dental glass-ionomer cements determines their leaching behavior and hence the properties of the cement. The objective of the present study was to assess if the composition and leaching in acetic acid solutions are reflected in the x-ray diffraction character...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345010800081601
更新日期：2001-08-01 00:00:00
abstract：:Chronic periodontitis is a multi-factorial disease involving anaerobic bacteria and the generation of an inflammatory response, including the production of metalloproteinases, pro-inflammatory cytokines, and eicosanoids. Hypochlorous acid (HOCl) and taurine-N-monochloramine (TauCl) are the end-products of the neutroph...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/154405910408301101
更新日期：2004-11-01 00:00:00
abstract：:Cleft palate is among the most common structural birth defects in humans. Previous studies have shown that mutations in FOXF2 are associated with cleft palate in humans and mice and that Foxf2 acts in a Shh-Foxf-Fgf18-Shh molecular network controlling palatal shelf growth. In this study, we combined RNA-seq and ChIP-s...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520904018
更新日期：2020-04-01 00:00:00
abstract：:Although dental amalgam is used frequently under artificial crowns for restoration of severely damaged teeth, there is little information available on the bond between luting cements and this alloy. This study was designed for determination of the strength of the bond between a dental amalgam alloy and three crown-lut...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345890680111501
更新日期：1989-11-01 00:00:00
abstract：:Tumor progression is often associated with altered glycosylation of the cell-surface proteins and lipids. The peripheral part of these cell-surface glycoconjugates often carries carbohydrate structures related to the ABO and Lewis blood-group antigens. The expression of histo-blood-group antigens in normal human tissu...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/154405910508400103
更新日期：2005-01-01 00:00:00
abstract：:The relationship between the serum IgG antibody titer against seven species of Gram-negative periodontopathic bacteria and clinical parameters (including plaque index, gingival index, periodontal pocket depth, and alveolar bone loss) was studied in 38 subjects. IgG antibody titer against the sonicated antigens was det...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345850640111101
更新日期：1985-11-01 00:00:00
abstract：:Cellular hypoxia may be a useful indication of tissue distress in the dental pulp that could be used to investigate the early stages of pulpal responses. Tritiated misonidazole (3H-MISO) is a marker which preferentially labels cells with decreased oxygen tension (hypoxia). The experiments reported here were carried ou...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345960750100801
更新日期：1996-10-01 00:00:00
abstract：:Hemifacial microsomia (HFM) is a congenital disorder marked by facial asymmetry. Whether facial asymmetry accounts for asymmetrical dental development is unknown. There are few data on dental development relative to mandibular development or severity of HFM, or on development over time. We hypothesized that when mandi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510378425
更新日期：2010-12-01 00:00:00
abstract：:Previous studies showed that residual compressive stresses induced by thermal tempering retarded the growth of surface cracks in bilayered porcelain disks. The objectives of the present study were: (1) to determine whether thermal tempering by air blasting reduces the length of cracks induced by microhardness indentat...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345960750020301
更新日期：1996-02-01 00:00:00
abstract：:Blood cortisol levels of oral surgery patients were analyzed to objectively determine the effect of intravenous sedation on surgical stress. Results showed a measure of sedation but did not adequately reflect the stress of oral surgery or the changes produced by intravenous sedation. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345750540053501
更新日期：1975-09-01 00:00:00
abstract：:Because bone reconstruction in irradiated sites is less than ideal, we applied a regenerative gene therapy method in which a cell-signaling virus was localized to biomaterial scaffolds to regenerate wounds compromised by radiation therapy. Critical-sized defects were created in rat calvariae previously treated with ra...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034509352151
更新日期：2010-01-01 00:00:00
abstract：:The relationship between periodontitis and systemic bone mineral density in Japanese women is undetermined. We tested the hypothesis that periodontitis was more frequent in women with low metacarpal bone mineral density (m-BMD). Subjects were 190 Japanese women (89 premenopausal, 101 post-menopausal). Periodontal stat...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345010800090901
更新日期：2001-09-01 00:00:00
abstract：:Dental caries is a microbially mediated disease that can result in significant tooth structure degradation. Although the preponderance of lesions is treated by surgical intervention, various strategies have been developed for its noninvasive management. Here, we use a novel approach for noninvasive treatment based on ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515619370
更新日期：2016-03-01 00:00:00
abstract：:Impacted human third molar teeth were examined, both with the light and electron microscope, to determine the extent of the odontoblast process. The odontoblast process was found to be limited to the inner third of coronal dentin and inner half of mid-root dentin. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/002203457905800412011
更新日期：1979-11-01 00:00:00
