LPS promotes pre-osteoclast activity by up-regulating CXCR4 via TLR-4.

abstract：:Dental epithelial progenitor cells differentiate into various cell types during development of tooth germs. To study this mechanism, we produced immortalized dental epithelial progenitor cells derived from the cervical-loop epithelium of a rat lower incisor. The expression patterns of cytokeratin 14, nerve growth fact...

journal_title：Journal of dental research

authors： Kawano S,Saito M,Handa K,Morotomi T,Toyono T,Seta Y,Nakamura N,Uchida T,Toyoshima K,Ohishi M,Harada H

更新日期：2004-02-01 00:00:00

abstract：:The regulation of blood flow of the dental pulp was investigated in dogs and rats anesthetized with sodium pentobarbital. Pulpal blood flow was altered by variations of local and systemic hemodynamics. Variation in pulpal hemodynamics was attained by means of close intra-arterial injections of adrenergic agonists (NE ...

journal_title：Journal of dental research

authors： Kim S

更新日期：1985-04-01 00:00:00

abstract：:Enamel abraders used in two-body wear tests suffer the disadvantage that standardization is difficult or impossible to obtain. The aim of this study was to test whether steatite (a ceramic material with a Vickers Hardness similar to that of enamel) could be used as a satisfactory human enamel analogue. The friction an...

journal_title：Journal of dental research

authors： Wassell RW,McCabe JF,Walls AW

更新日期：1994-09-01 00:00:00

abstract：:Recent functional animal studies have reported that the motor control of masticatory muscle function is bilaterally guided by both hemispheres, which may fundamentally differ from the cortical control of limb muscle function. In this study, we investigated whether unilateral cortical brain infarction induces different...

journal_title：Journal of dental research

authors： Kemppainen P,Waltimo A,Palomäki H,Salonen O,Könönen M,Kaste M

更新日期：1999-12-01 00:00:00

abstract：:The fluid in and gingival tissue lining periodontal pockets were collected from male patients undergoing periodontal therapy. The collagenolytic activity of the crevicular fluid, and the ability of the gingiva in culture to degrade (a) an exogenous collagen substrate, and (b) endogenous collagen newly synthesized and ...

journal_title：Journal of dental research

authors： Golub LM,Kaplan R,Mulvihill JE,Ramamurthy NS

更新日期：1979-11-01 00:00:00

abstract：:One-step incomplete excavation seals caries-affected dentin under a restoration and appears to be advantageous in the treatment of deep lesions. However, it is impossible to discriminate radiographically between intentionally left, arrested lesions and overlooked or active lesions. This diagnostic uncertainty decrease...

journal_title：Journal of dental research

authors： Schwendicke F,Meyer-Lueckel H,Schulz M,Dörfer CE,Paris S

更新日期：2014-06-01 00:00:00

abstract：:The initiator of calculus matrix calcification, in vitro, was isolated. Crude phospholipid, known to contain the factor, was separated into five fractions by column chromatography. A single protein-containing fraction induced apatite formation during incubation. The nucleating fraction was indentified as a proteolipid...

journal_title：Journal of dental research

authors： Ennever J,Vocel JJ,Riggan LJ,Paloski SB

更新日期：1977-02-01 00:00:00

abstract：:Cementum is known to be growth-hormone (GH)-responsive, but to what extent is unclear. This study examines the effects of extremes of GH status on cementogenesis in three lines of genetically modified mice; GH excess (giant), GH antagonist excess (dwarf), and GH receptor-deleted (GHR-KO) (dwarf). Age-matched mandibula...

journal_title：Journal of dental research

authors： Smid JR,Rowland JE,Young WG,Daley TJ,Coschigano KT,Kopchick JJ,Waters MJ

更新日期：2004-01-01 00:00:00

abstract：:The sequelae of sustained, in vivo delivery of two important neurotransmitter substances, glutamate and thyrotropin-releasing hormone (TRH), upon craniofacial growth and development have previously not been investigated. Our purpose was to document and compare the relative effects of glutamate and TRH microspheres ste...

journal_title：Journal of dental research

authors： Byrd KE,Sukay MJ,Dieterle MW,Yang L,Marting TC,Teomim D,Domb AJ

更新日期：1997-08-01 00:00:00

abstract：:Although the occlusal vertical dimension (OVD) is strictly controlled, the neuronal mechanism of its regulation is still unclear. We hypothesize that neurons in the trigeminal mesencephalic nucleus (MesV) play an important role in the regulation of the OVD, because the MesV receives the projection from jaw-closing mus...

journal_title：Journal of dental research

authors： Zhang W,Kobayashi M,Moritani M,Masuda Y,Dong J,Yagi T,Maeda T,Morimoto T

更新日期：2003-07-01 00:00:00

abstract：:Odontoblasts, with their strategic arrangement along the outermost compartment of the dentin-pulp complex, have been suggested to have sensory function. In addition to their primary role in dentin formation, growing evidence shows that odontoblasts are capable of sensing mechanical stimulation. Previously, we found th...

journal_title：Journal of dental research

authors： Won J,Vang H,Kim JH,Lee PR,Kang Y,Oh SB

更新日期：2018-08-01 00:00:00

abstract：:Branching morphogenesis is essential for the formation of salivary glands, kidneys, lungs, and many other organs during development, but the mechanisms underlying this process are not adequately understood. Microarray and other gene expression methods have been powerful approaches for identifying candidate genes that ...

journal_title：Journal of dental research

authors： Hsu JC,Di Pasquale G,Harunaga JS,Onodera T,Hoffman MP,Chiorini JA,Yamada KM

更新日期：2012-02-01 00:00:00

abstract：:The etiology and pathogenesis of craniofacial birth defects are multifactorial and include both genetic and environmental factors. Despite the identification of numerous genes associated with congenital craniofacial anomalies, our understanding of their etiology remains incomplete, and many affected individuals have a...

journal_title：Journal of dental research

authors： Dash S,Bhatt S,Falcon KT,Sandell LL,Trainor PA

更新日期：2020-11-06 00:00:00

abstract：:A detailed understanding of the complexity of root canal systems is imperative to ensure successful root canal preparation. The aim of this study was to evaluate the potential and accuracy of a three-dimensional, non-destructive technique for detailing root canal geometry by means of high-resolution tomography. The an...

journal_title：Journal of dental research

authors： Peters OA,Laib A,Rüegsegger P,Barbakow F

更新日期：2000-06-01 00:00:00

abstract：:The effect of combined administration of chlorhexidine and fluoride in the drinking water of hamsters on plaque and caries prevention was studied. Plaque indices of the hamsters receiving chlorhexidine either alone or simultaneously with fluoride were significantly lower than those of the control and fluoride only tre...

journal_title：Journal of dental research

authors： Brayer L,Gedalia I,Gover A

更新日期：1977-11-01 00:00:00

abstract：:The Kubelka-Munk (K-M) theory provides a reflectance model for translucent materials placed on backings of different colors. We hypothesize that Kubelka-Munk (K-M) theoretical diffuse reflectance spectra of dentin and enamel are in good agreement with observed diffuse reflectance. The aim of this study was to measure ...

journal_title：Journal of dental research

authors： Ragain JC Jr,Johnston WM

更新日期：2001-02-01 00:00:00

abstract：:A model system consisting of vacuum-deposited aluminum on glass was developed to demonstrate the effectiveness of cavitational activity (occurring within the cooling water supply of a dental ultrasonic scaler) in the removal of particulate material from solid surfaces. The amount of solid material removed from the mod...

journal_title：Journal of dental research

authors： Walmsley AD,Laird WR,Williams AR

更新日期：1984-09-01 00:00:00

abstract：:Known antimalarial compunds from several chemical classes were tested for their ability to inhibit in vitro growth of microorganisms causing dental plaque and to prevent the development of plaque in a hamster model. Approximately a third of the compounds tested inhibited in vitro growth; however, none prevented develo...

journal_title：Journal of dental research

authors： Kinnamon KE,Eckermann EH,Tempel TR,Smith JH,Wolf CR

更新日期：1975-05-01 00:00:00

abstract：:Application of an incisal bite plane for as little as three d caused a significant increase in the size of the sublingual glands of rats, with some evidence of hyperplasia and hypertrophy of the acinar cells. The enlargement had few effects on salivary secretion, and the gland changes were reversible. ...

journal_title：Journal of dental research

authors： Hioki S,Niwa K,Kishimoto T,Kawazoe T,Yokota Y,Abe K,Dawes C

更新日期：1983-06-01 00:00:00

abstract：:Extracellular microcapsules have been demonstrated on cells of most serotypes of Streptococcus mutans by electron microscopy, using bacterial strains of the various serotypes and peroxidase labeled or unlabeled immune serum. A correlation was noted between the amount of capsular substance on the strains of S mutans ex...

journal_title：Journal of dental research

authors： Grenier EM,Gray RH,Loesche WJ,Eveland WC

更新日期：1977-02-01 00:00:00

abstract：:The destabilizing effect of endodontic treatment upon teeth is still controversial. The purpose of this study was to investigate the effects of different steps of endodontic treatments upon the rigidity of teeth. Extracted untreated central maxillary anterior teeth were loaded (3.75 N), and deformations of the root we...

journal_title：Journal of dental research

authors： Lang H,Korkmaz Y,Schneider K,Raab WH

更新日期：2006-04-01 00:00:00

abstract：:In an attempt to make a dynamic study of the isoelectric point and the chargeability of human dental enamel, an electrochemical approach was utilized. Zeta potential of three kinds of the enamel was measured by a streaming potential method. As a result, these isoelectric points could be decided. ...

journal_title：Journal of dental research

authors： Kambara M,Asai T,Kumasaki M,Konishi K

更新日期：1978-02-01 00:00:00

abstract：:The aim of this study was to investigate the diffusion dynamics of 25% hydrogen peroxide (H2O2) through enamel-dentin layers and to correlate it with dentin's structural alterations. Micro-Raman Spectroscopy (MRS) and Fourier Transform Infrared Photoacoustic Spectroscopy (FTIR-PAS) were used to measure the spectra of ...

journal_title：Journal of dental research

authors： Ubaldini AL,Baesso ML,Medina Neto A,Sato F,Bento AC,Pascotto RC

更新日期：2013-07-01 00:00:00

abstract：:The aim of the present study was to describe the patterns of dental fluorosis in the primary and the permanent dentition of children born and reared in two different fluoridated areas, one in which powdered milk suspended in tap water was commonly used (Narssaq, Greenland: 1.1 ppm fluoride in the water) and one in whi...

journal_title：Journal of dental research

authors： Larsen MJ,Senderovitz F,Kirkegaard E,Poulsen S,Fejerskov O

更新日期：1988-05-01 00:00:00

abstract：:In 1992 and 1997, all US and Canadian dental schools were surveyed by mail regarding the preferred initial radiographic examination prescribed for non-emergency, comprehensive-care patients (dentulous adults, edentulous adults, and children). In both survey years, a minority of US and Canadian dental schools reported ...

journal_title：Journal of dental research

authors： Kantor ML

更新日期：2000-07-01 00:00:00

abstract：:During periods of periodontal attachment loss, one of the most significant cellular changes is a decrease in the number of fibroblasts. We previously demonstrated that LPS induces apoptosis of fibroblastic cells in vivo, largely through TNF-alpha. We conducted in vivo experiments by subcutaneous inoculation of LPS in ...

journal_title：Journal of dental research

authors： Alikhani M,Alikhani Z,Graves DT

更新日期：2004-09-01 00:00:00

abstract：:Fibroblast growth factor receptor 2 (FGFR2) in craniofacial bones mediates osteoprogenitor proliferation, differentiation, and apoptosis. The distortion of proper craniofacial bone growth may cause class II and class III skeletal malocclusion and result in compromised function and aesthetics. Here, we investigated the...

journal_title：Journal of dental research

authors： Jiang Q,Mei L,Zou Y,Ding Q,Cannon RD,Chen H,Li H

更新日期：2019-11-01 00:00:00

abstract：:Tooth agenesis is one of the most common developmental anomalies affecting function and esthetics. The paired-domain transcription factor, Pax9, is critical for patterning and morphogenesis of tooth and taste buds. Mutations of PAX9 have been identified in patients with tooth agenesis. Despite significant progress in ...

journal_title：Journal of dental research

authors： Wong SW,Han D,Zhang H,Liu Y,Zhang X,Miao MZ,Wang Y,Zhao N,Zeng L,Bai B,Wang YX,Liu H,Frazier-Bowers SA,Feng H

更新日期：2018-02-01 00:00:00

abstract：:The creatinine-adjusted urinary concentration of mercury in 73 schoolchildren with a mean age of 12 years was determined. In addition, the number of amalgam restorations and their size, prevalence of allergy, and days absent from school due to illness were recorded for each individual. A significant positive correlati...

journal_title：Journal of dental research

authors： Olstad ML,Holland RI,Wandel N,Pettersen AH

更新日期：1987-06-01 00:00:00

abstract：:Breastfeeding is important for health and development. Yet, the interaction between breastfeeding duration and usage of fluoridated water on caries experience has not been investigated. This study examined exposure to fluoridation as an effect modifier of the association between breastfeeding duration and caries. The ...

journal_title：Journal of dental research

authors： Ha DH,Spencer AJ,Peres KG,Rugg-Gunn AJ,Scott JA,Do LG

更新日期：2019-07-01 00:00:00