Abstract：
:The fluid in and gingival tissue lining periodontal pockets were collected from male patients undergoing periodontal therapy. The collagenolytic activity of the crevicular fluid, and the ability of the gingiva in culture to degrade (a) an exogenous collagen substrate, and (b) endogenous collagen newly synthesized and labeled with H3-hydroxyproline, were related to the severity of gingival inflammation. Although inflammation appeared to have only a slight effect on gingival collagenolytic activity and on the turnover of collagen newly synthesized in culture, a marked effect was observed on the collagenase activity in the crevicular fluid. This study suggests that the collagen destructive activity of the periodontal lesion can be assessed by monitoring crevicular fluid collagenolytic activity.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Golub LM,Kaplan R,Mulvihill JE,Ramamurthy NSdoi
10.1177/00220345790580111601subject
Has Abstractpub_date
1979-11-01 00:00:00pages
2132-6issue
11eissn
0022-0345issn
1544-0591journal_volume
58pub_type
杂志文章abstract：:T6 antigen is a highly specific marker for human Langerhans cells (LC). Previous studies have demonstrated that Interleukin-1 (IL-1) and an IL-1 inhibitor (ILS) modulate LC T6 expression (T6E) in explant culture. The present study examined the in vitro modulation of T6E by two molecules: epidermal-cell-derived thymocy...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345870660031201
更新日期：1987-03-01 00:00:00
abstract：:Samples of a base mental alloy were cast and welded together using a conventional welding procedure. The joints were loaded and placed either in a corrosive environment or in air for varying time periods. The tensile and shear strength of the joints was unaffected by the corrosive environment, and the joints, despite ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345810600021101
更新日期：1981-02-01 00:00:00
abstract：:Previous studies have shown that therapeutic pulsed ultrasound (pulsed) has superior stimulatory effect on bone fracture healing compared with continuous ultrasound (continuous). Our predictive hypothesis was that pulsed ultrasound can produce better bone formation during mandibular osteodistraction than continuous ul...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910808701018
更新日期：2008-10-01 00:00:00
abstract：:The pellicle serves as a multifunctional protective layer, providing, e.g., lubrication and remineralization and also acting as a diffusion barrier. In addition, since the formation of the pellicle precedes the adhesion of micro-organisms, it is also important as a conditioning film. We present a novel approach to stu...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034512456704
更新日期：2012-10-01 00:00:00
abstract：:Breastfeeding is important for health and development. Yet, the interaction between breastfeeding duration and usage of fluoridated water on caries experience has not been investigated. This study examined exposure to fluoridation as an effect modifier of the association between breastfeeding duration and caries. The ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034519843487
更新日期：2019-07-01 00:00:00
abstract：:A major extracellular protein of cultured adult human gingival fibroblasts was shown to be fibronectin by indirect immunofluorescence, lactoperoxidase catalyzed iodination and metabolic radiolabeling. Fibronectin preparations from these cells possessed the biological properties of agglutination of sheep red blood cell...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345800590031301
更新日期：1980-03-01 00:00:00
abstract：:Branching morphogenesis is essential for the formation of salivary glands, kidneys, lungs, and many other organs during development, but the mechanisms underlying this process are not adequately understood. Microarray and other gene expression methods have been powerful approaches for identifying candidate genes that ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034511429346
更新日期：2012-02-01 00:00:00
abstract：:The Kubelka-Munk (K-M) theory provides a reflectance model for translucent materials placed on backings of different colors. We hypothesize that Kubelka-Munk (K-M) theoretical diffuse reflectance spectra of dentin and enamel are in good agreement with observed diffuse reflectance. The aim of this study was to measure ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345010800020901
更新日期：2001-02-01 00:00:00
abstract：:Since 1935, various mechanisms have been suggested for the formation of subsurface lesions and, in particular, the surface layer covering enamel lesions. The relatively intact mineral-rich and porous surface layer is most likely caused by kinetic events. The suggested mineral-rich outer layer in sound enamel, the orga...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/00220345860650010201
更新日期：1986-01-01 00:00:00
abstract：:Dissolution of mercury from amalgams and some intermetallic compounds found in the amalgam structure, such as gamma 1, gamma 2, and beta 1, was examined during one week of aging in 0.9% NaCl solution at 37 degrees C. The amount of mercury released from gamma 1 (30.2 micrograms/cm2) was at least 13 times that released ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345870660010701
更新日期：1987-01-01 00:00:00
abstract：:In this study, we first investigated the expressions of Jagged1, Notch2, the receptor activator of nuclear factor-kappa B ligand (RANKL), and interleukin (IL)-6 in areas of root resorption during experimental tooth movement in rats in vivo. We then assessed the effects of compression force (CF) with or without GSI (an...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034514555364
更新日期：2015-01-01 00:00:00
abstract：:Severe early childhood caries (S-ECC) is a multifactorial disease that can lead to suffering and reduced oral health-related quality of life in young children. The bacterial and fungal composition of dental plaque and how children's sex is associated with S-ECC are largely unknown. In this study, V4-16S rRNA and ITS1 ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520908595
更新日期：2020-06-01 00:00:00
abstract：:Titanium-polymethacrylate composite was prepared as an x-ray-opaque filler for composite core materials. The base monomers of the composite were 2,2-bis [4-(3-methacryloyloxy-2-hydroxypropoxy) phenyl] propane (Bis-GMA) and triethyleneglycol dimethacrylate (TEGDMA). Pure titanium powder was used as a radiopaque element...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345920710010201
更新日期：1992-01-01 00:00:00
abstract：:Adenosine has various biological effects on human gingival fibroblasts (HGF) and epithelial cells closely associated with inflammation, such as cytokine production and cell adhesion. However, the mechanism of adenosine formation in periodontal tissues is not yet defined. In this study, we examined the involvement of C...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910308201108
更新日期：2003-11-01 00:00:00
abstract：:The oral microbiota was compared between Romanian adolescents with a high prevalence of caries and no dental care and Swedish caries-active and caries-free adolescents in caries prevention programs and with a low prevalence of caries. Biofilm samples were analyzed by FLX+ pyrosequencing of the V1 to V4 hypervariable r...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515609554
更新日期：2016-01-01 00:00:00
abstract：:In this study, we investigated whether selective activation of nociceptive primary afferent fibers by capsaicin would induce modulations on tooth-pulp-evoked sensory or inhibitory masseter reflex responses in healthy human subjects. The contribution of central N-methyl-D-aspartate (NMDA) receptor mechanisms in capsaic...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345970760090801
更新日期：1997-09-01 00:00:00
abstract：:Seven ATCC strains of bacteria were examined for apatite formation in a chemically-defined calcification-supporting medium and also in a metastable calcium phosphate solution. One, E. coli, calcified in both. One, S. aureus, calcified in the solution, but not in the medium. The other five did not calcify in either. Th...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345810600101001
更新日期：1981-10-01 00:00:00
abstract：:A conceptual means of obtaining improved bonding between filler particles and the polymeric binders of composites is presented. It involves preparing glass particles that separate into two interconnected vitreous phases when heated to an appropriate temperature, and then etching these to produce a porous surface layer...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345760550050701
更新日期：1976-09-01 00:00:00
abstract：:The human patched gene (PTCH) functions in both embryologic development and tumor suppression. PTCH mutations have been found in odontogenic keratocysts. However, the expression and localization of the protein product of the gene have not been determined in odontogenic tumors and cysts. We investigated 68 odontogenic ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0810757
更新日期：2002-11-01 00:00:00
abstract：:The whisker pad area (WP) is innervated by the second branch of the trigeminal nerve and experiences allodynia and hyperalgesia following transection of the mental nerve (MN; the third branch of the trigeminal nerve). However, the mechanisms of this extra-territorial pain remain unclear. The ionotropic P2X(7) ATP rece...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034512474668
更新日期：2013-03-01 00:00:00
abstract：:Although it is known that diabetes impairs oral wound healing, relatively little is known about the cellular parameters affected, particularly in connective tissue. This study investigated the hypothesis that diabetes impairs connective tissue formation in healing gingiva, and that impaired healing is associated with ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510362960
更新日期：2010-06-01 00:00:00
abstract：:In the past two decades, accumulated evidence has clearly demonstrated the inhibitory effects of laser irradiation on enamel demineralization, but the exact mechanisms of these effects remain unclear. The purpose of this study was to investigate the effects of low-energy CO2 laser irradiation on demineralization of bo...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345000790091401
更新日期：2000-09-01 00:00:00
abstract：:Nitric oxide (.NO) modulates the activity of the endocrine system in the behavioral response to stress. The purpose of this study was to investigate the effect of restraining the body of an animal on expression of neuronal nitric oxide synthase (nNOS) in the paraventricular nucleus (PVN) of the hypothalamus, and the i...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910508400708
更新日期：2005-07-01 00:00:00
abstract：:The human dentition is a complex adaptive system that is influenced by genetic, epigenetic, and environmental factors. Within this system, is sexual dimorphism related to the growth promotion of the Y chromosome, or to hormonal influences, or both? This study is the first to investigate both primary and permanent toot...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513484934
更新日期：2013-05-01 00:00:00
abstract：:Epithelial-mesenchymal interactions are required for tooth formation. Bone morphogenetic protein 4 (Bmp4) is a crucial signaling molecule during this process. For better understanding of the role of the Bmp4 gene during tooth development, we studied the mechanisms that control its temporal and spatial expression durin...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/002203450208100103
更新日期：2002-01-01 00:00:00
abstract：:Our observations confirm the previously reported observation that multinucleated cells develop within a two-week period in cat bone-marrow cultures. Calcitonin induces cytoplasmic contraction in these multinucleated cells, which indicates that they resemble osteoclasts. After seven days of culture, cat bone-marrow cul...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650070201
更新日期：1986-07-01 00:00:00
abstract：:The feasibility of immunizing monkeys with enzymes from oral streptococci in an attempt to reduce dental caries was investigated. Forty rhesus monkeys, Macaca mulatta, were used. Cariogenic streptococci, S mutans, were implanted into all the monkeys' mouths. There was no pathological effect resulting from immunization...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560123001
更新日期：1977-12-01 00:00:00
abstract：:The dental pulp in human primary teeth is densely innervated by a plethora of nerve endings at the coronal pulp-dentin interface. This study analyzed how the physiological root resorption (PRR) process affects dental pulp innervation before exfoliation of primary teeth. Forty-four primary canine teeth, classified into...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515593055
更新日期：2015-10-01 00:00:00
abstract：:The field of dental materials has undergone more of a revolution than an evolution over the past 100 y. The development of new products, especially in the past half century, has occurred at a staggering pace, and their introduction to the market has been equally impressive. The movement has mostly come in the area of ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034518822808
更新日期：2019-03-01 00:00:00
abstract：:During the setting of a resin composite cement (RCC) used as an adhesive between a resin-bonded bridge and tooth structure, the adhesion may be disrupted by the development of shrinkage stress. The aim of this study was to investigate the influence of the shrinkage stress of three different RCCs on their adhesive and ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345920710021101
更新日期：1992-02-01 00:00:00
