Identification of cis-DNA regions controlling Bmp4 expression during tooth morphogenesis in vivo.

abstract：:The proton probe has been used to map F concentration changes in the enamel of 15 teeth showing clinical evidence of caries. Thin sections through the lesions were microradiographed and measurements made of the surface zone (radiodense) and body (radiolucent) areas. Each section was then scanned with a focused beam of...

journal_title：Journal of dental research

authors： Pearce EI,Coote GE,Larsen MJ

更新日期：1995-11-01 00:00:00

abstract：:The ability of adhesive resins to restore the physical properties of demineralized dentin has not been well-documented. The unfilled resins that are used for adhesion have relatively low moduli of elasticity and limited ability to increase dentin stiffness, although they may increase the ultimate tensile strength of d...

journal_title：Journal of dental research

authors： Sano H,Takatsu T,Ciucchi B,Russell CM,Pashley DH

更新日期：1995-04-01 00:00:00

abstract：:Oxygen inhibits polymerization of resin-based materials. We hypothesized that compromised bonding to bleached enamel can be reversed with sodium ascorbate, an anti-oxidant. Sandblasted human enamel specimens were treated with distilled water (control) and 10% carbamide peroxide gel with or without further treatment wi...

journal_title：Journal of dental research

authors： Lai SC,Tay FR,Cheung GS,Mak YF,Carvalho RM,Wei SH,Toledano M,Osorio R,Pashley DH

更新日期：2002-07-01 00:00:00

abstract：:The benefits of early orthodontic treatment are continuously discussed, but studies are few. We examined whether definite need for orthodontic treatment could be eliminated in public health care by systematically focusing on early intervention. One age cohort living in a rural Finnish municipality (N = 85) was regular...

journal_title：Journal of dental research

authors： Kerosuo H,Väkiparta M,Nyström M,Heikinheimo K

更新日期：2008-06-01 00:00:00

abstract：:A series of 4,6-dichloro-1,3,5-triazines [e.g., 2-allylamino-(ADT), diallylamino-(DADT), 2-N-p-allyloxyphenylamino-, 2-N-allyl-N-phenylamino-, and 2-N-allyl-N-p-tolylamino-4,6-dichloro-1,3,5-triazine] was synthesized and characterized by IR, NMR, and mass spectrometry. These monomers have chlorine atoms that can react...

journal_title：Journal of dental research

authors： Lee CH,Liu XQ,Gong XQ

更新日期：1986-12-01 00:00:00

abstract：:Moderate elevation of serum C-reactive protein (CRP) is a risk factor for cardiovascular disease among apparently healthy individuals, although factors that create this inflammatory response in the absence of systemic illness have not been clarified. This study aimed to: (1) evaluate associations among periodontal dis...

journal_title：Journal of dental research

authors： Slade GD,Offenbacher S,Beck JD,Heiss G,Pankow JS

更新日期：2000-01-01 00:00:00

abstract：:It has been shown that a release of periosteal tension may augment the growth of a long bone; however, similar experiments in the mandible have produced equivocal results. For further definition of the role of periosteal tension in the growth of the mandibular condyle, 80 young female Sprague-Dawley rats were randomly...

journal_title：Journal of dental research

authors： Killiany DM

更新日期：1990-09-01 00:00:00

abstract：:The hypothesis that periodontal disease is associated with pre-term low birthweight was tested in a prospective follow-up study of rural prima-gravida women (N = 227) who were free of tobacco, alcohol, and drug use. Women with 3rd trimester mean probing pocket depths, plaque, and bleeding scores that were greater than...

journal_title：Journal of dental research

authors： Rajapakse PS,Nagarathne M,Chandrasekra KB,Dasanayake AP

更新日期：2005-03-01 00:00:00

abstract：:Human tooth wear occurs so slowly that traditionally it has needed months or years to be measurable. This study showed that microscopic changes in wear patterns on human teeth could be detected in a matter of days and could be used as indicators of rates of wear. Thus, daily or weekly changes in rates of wear can be d...

journal_title：Journal of dental research

authors： Teaford MF,Tylenda CA

更新日期：1991-03-01 00:00:00

abstract：:An analysis of the relationship between creep and microstructural characteristics of several gamma2-containing amalgams showed the grain size of the Ag-Hg phase (gamma1) to be a predominant factor influencing creep. When gamma1 grain size is increased, creep is reduced. ...

journal_title：Journal of dental research

authors： Mahler DB,Adey JD,Marantz RL

更新日期：1977-12-01 00:00:00

abstract：:Resin-bonded bridges may replace missing teeth and act as splints in periodontal treatment. The objective of this study was to investigate the etch pattern after electrolytic etching of selected Co-Cr alloys in hydrochloric acid and to assess the changes in alloy composition after different etching times. The alloys i...

journal_title：Journal of dental research

authors： Ekstrand K,Ruyter IE

更新日期：1987-09-01 00:00:00

abstract：:When one uses composite resins, the curing contraction, the stiffness of the material, and the strength of the vulnerable dentinal bond are important factors in determining the marginal adaptation of the restoration. Calculations based on these intrinsic material properties have indicated that both bulk placement and ...

journal_title：Journal of dental research

authors： Kemp-Scholte CM,Davidson CL

更新日期：1988-05-01 00:00:00

abstract：:Periodontal disease is a bacterial infection that results in inflammatory destruction of tissues that support the teeth, including connective tissue and bone. In this study, we report that transgenic mice that overexpress the 17-kDa form of IL-1alpha in the basal layer of oral mucosal epithelium develop a syndrome tha...

journal_title：Journal of dental research

authors： Dayan S,Stashenko P,Niederman R,Kupper TS

更新日期：2004-10-01 00:00:00

abstract：:The aim of this study was to assess the effect of chewing gum containing phosphoryl oligosaccharides of calcium (POs-Ca) and a low concentration of fluoride (F) on the hardness of enamel subsurface lesions, utilizing a double-blind, randomized, and controlled in situ model. Fifteen individuals wore removable lingual a...

journal_title：Journal of dental research

authors： Kitasako Y,Sadr A,Hamba H,Ikeda M,Tagami J

更新日期：2012-04-01 00:00:00

abstract：:Relative glycogen synthetic abilities of resting cells of fresh clinical isolates of Actinomyces viscosus and Actinomyces naeslundii originating from dental plaque samples over root surface caries lesions and non-carious sites were studied under anaerobic conditions at a constant pH of 7.0, with U-(14C)-glucose used a...

journal_title：Journal of dental research

authors： Komiyama K,Khandelwal RL,Duncan DE

更新日期：1986-06-01 00:00:00

abstract：:Understanding the mechanical properties of human teeth is important to clinical tooth preparation and to the development of "tooth-like" restorative materials. Previous studies have focused on the macroscopic fracture behavior of enamel and dentin. In the present study, we performed indentation studies to understand t...

journal_title：Journal of dental research

authors： Xu HH,Smith DT,Jahanmir S,Romberg E,Kelly JR,Thompson VP,Rekow ED

更新日期：1998-03-01 00:00:00

abstract：:The importance of assessing the impact of treatments for chronic conditions on an individual's quality of life has been well-established. In this randomized clinical trial, oral-health-related quality of life, measured with the Oral Health Impact Profile (OHIP), was compared between two groups of edentulous patients. ...

journal_title：Journal of dental research

authors： Awad MA,Locker D,Korner-Bitensky N,Feine JS

更新日期：2000-09-01 00:00:00

abstract：:Primary cilia regulate several developmental processes and mediate hedgehog signaling. To study their roles in cranial base development, we created conditional mouse mutants deficient in Polaris, a critical primary cilium component, in cartilage. Mutant post-natal cranial bases were deformed, and their synchondrosis g...

journal_title：Journal of dental research

authors： Ochiai T,Nagayama M,Nakamura T,Morrison T,Pilchak D,Kondo N,Hasegawa H,Song B,Serra R,Pacifici M,Koyama E

更新日期：2009-06-01 00:00:00

abstract：:In the past decade, medical genetic research has generated multiple discoveries, many of which were obtained via genome-wide association studies (GWASs). A major GWAS finding is that the majority of risk variants for complex traits map to noncoding regions. This has resulted in a paradigm shift in terms of the interpr...

journal_title：Journal of dental research

authors： Thieme F,Ludwig KU

更新日期：2017-10-01 00:00:00

abstract：:In mammals, the periodontal ligament (PDL) is a highly specialized tissue which facilitates tooth eruption and lends mechanical support to the tooth once in occlusion. The PDL extracellular matrix fibers play a major role in such functions. During its development, the spatial arrangement of the PDL extracellular matri...

journal_title：Journal of dental research

authors： Karimbux NY,Rosenblum ND,Nishimura I

更新日期：1992-07-01 00:00:00

abstract：:In cases of pulp exposure due to deep dental caries or severe traumatic injuries, existing pulp-capping materials have a limited ability to reconstruct dentin-pulp complexes and can result in pulpectomy because of their low potentials to accelerate dental pulp cell activities, such as migration, proliferation, and dif...

journal_title：Journal of dental research

authors： Yoshida S,Wada N,Hasegawa D,Miyaji H,Mitarai H,Tomokiyo A,Hamano S,Maeda H

更新日期：2016-10-01 00:00:00

abstract：:In this study, environmental stains were removed from maxillofacial elastomers by solvent extraction. Silastic 44210, an RTV silicone with proven color and physical property stability, was stained with lipstick, disclosing solution, and methylene blue. These stains were then removed by solvent extraction with each of ...

journal_title：Journal of dental research

authors： Yu R,Koran A,Raptis CN,Craig RG

更新日期：1981-10-01 00:00:00

abstract：:Purinergic signaling is involved in pain generation and modulation in the nociceptive sensory nervous system. Adenosine triphosphate (ATP) induces pain via activation of ionotropic P2X receptors while adenosine mediates analgesia via activation of metabotropic P1 receptors. These purinergic signaling are determined by...

journal_title：Journal of dental research

authors： Liu X,Ma L,Zhang S,Ren Y,Dirksen RT

更新日期：2017-06-01 00:00:00

abstract：:Periodontal inflammation and alveolar bone remodeling during orthodontic tooth movement are considered regional reactions. However, how systemic immune responses are involved in this regional reaction remains unclear. In this study, we explored the systemic effects of orthodontic force by focusing on the mononuclear p...

journal_title：Journal of dental research

authors： Zeng M,Kou X,Yang R,Liu D,Wang X,Song Y,Zhang J,Yan Y,Liu F,He D,Gan Y,Zhou Y

更新日期：2015-09-01 00:00:00

abstract：:The aim of this meta-analysis was to examine the clinical effectiveness of miniscrew implants (MI) used for anchorage reinforcement compared with that of conventional orthodontic means, as well as to assess the success rates of MIs and the possible risk factors affecting their clinical effectiveness. Literature search...

journal_title：Journal of dental research

authors： Papadopoulos MA,Papageorgiou SN,Zogakis IP

更新日期：2011-08-01 00:00:00

abstract：:Nearly 100% of patients experience trauma to the trigeminal nerve during orthognathic surgery, impairing sensation and sensory function on the face. In a recent randomized clinical trial, people who performed sensory re-training exercises reported less difficulty related to residual numbness and decreased lip sensitiv...

journal_title：Journal of dental research

authors： Essick GK,Phillips C,Zuniga J

更新日期：2007-06-01 00:00:00

abstract：:Acculturation is a complex phenomenon that can serve as a proxy for cultural norms and behaviors affecting care-seeking, prevention behaviors, and, ultimately, health outcomes. The purpose of this study was to assess the effect of acculturation on the oral health of Haitian immigrants in New York City. We hypothesized...

journal_title：Journal of dental research

authors： Cruz GD,Shore R,Le Geros RZ,Tavares M

更新日期：2004-02-01 00:00:00

abstract：:Epstein-Barr virus (EBV), in addition to its transforming properties, contributes to the pathogenesis of several inflammatory diseases. Here, we investigated its involvement in oral lichen planus (OLP), a common autoimmune-like disease of unknown etiopathogenesis that can display a malignant potential. EBV-infected ce...

journal_title：Journal of dental research

authors： Raybaud H,Olivieri CV,Lupi-Pegurier L,Pagnotta S,Marsault R,Cardot-Leccia N,Doglio A

更新日期：2018-12-01 00:00:00

abstract：:The accelerating activity of N,N-substituted aminoethyl methacrylates on the curing of methyl methacrylate and composite resins with benzoyl peroxide is somewhat smaller than that of dimethyl-p-toluidine. Tesins cured with aminoethyl methacrylates containing a p-tolyl and 3,5-xylyl substituent on the nitrogen atom tur...

journal_title：Journal of dental research

authors： Dneboský J,Hynková V,Hrabák F

更新日期：1975-07-01 00:00:00

abstract：:Secondary palatogenesis occurs when the bilateral palatal shelves (PS), arising from maxillary prominences, fuse at the midline, forming the hard and soft palate. This embryonic phenomenon involves a complex array of morphogenetic events that require coordinated proliferation, apoptosis, migration, and adhesion in the...

journal_title：Journal of dental research

authors： Lough KJ,Byrd KM,Spitzer DC,Williams SE

更新日期：2017-10-01 00:00:00