Abstract：
:The proton probe has been used to map F concentration changes in the enamel of 15 teeth showing clinical evidence of caries. Thin sections through the lesions were microradiographed and measurements made of the surface zone (radiodense) and body (radiolucent) areas. Each section was then scanned with a focused beam of 2.5 MeV protons, 2000 spot analyses being performed over areas up to 2 x 3 mm. F was determined by detecting gamma rays from a nuclear reaction and the data used to construct 3-D surface plots. The maximum F concentration in the lesion surface zone was extremely variable, ranging from 1750 to 21,700 ppm, and rarely occurred over the deepest part of the lesion. F levels were elevated in the lesion body but usually to a small extent only. A large increase in F throughout the lesion body was found in 3 lesions only, and was associated with a surface zone that was thin or of low x-ray density. Relatively small F increases in the lesion body were associated with either a thick, x-ray dense surface layer having a greatly increased F level (> 10,000 ppm) or, conversely, with a surface layer having a relatively small F increase. Since F uptake can be regarded as a "marker" of past remineralization events, this study shows that remineralization can and does occur in the body of natural enamel caries lesions, especially when the surface layer is thin or lost. Fluoride availability that encourages the formation of an extremely dense surface layer may result in under-achievement of this natural repair process in the lesion body.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Pearce EI,Coote GE,Larsen MJdoi
10.1177/00220345950740111001subject
Has Abstractpub_date
1995-11-01 00:00:00pages
1775-82issue
11eissn
0022-0345issn
1544-0591journal_volume
74pub_type
杂志文章abstract：:Patients suffering from temporomandibular dysfunction exhibit clinical findings such as fatigue, painful muscles, and muscles that are tender to palpation, not only in the temporomandibular area, but also in the neck/shoulder region. The mechanisms behind this are not known, although previous studies of similar spread...
journal_title：Journal of dental research
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abstract：:The destabilizing effect of endodontic treatment upon teeth is still controversial. The purpose of this study was to investigate the effects of different steps of endodontic treatments upon the rigidity of teeth. Extracted untreated central maxillary anterior teeth were loaded (3.75 N), and deformations of the root we...
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abstract：:Cleft palate is among the most common structural birth defects in humans. Previous studies have shown that mutations in FOXF2 are associated with cleft palate in humans and mice and that Foxf2 acts in a Shh-Foxf-Fgf18-Shh molecular network controlling palatal shelf growth. In this study, we combined RNA-seq and ChIP-s...
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journal_title：Journal of dental research
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doi：10.1177/0022034511404703
更新日期：2011-07-01 00:00:00
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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更新日期：1980-03-01 00:00:00
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journal_title：Journal of dental research
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更新日期：1988-06-01 00:00:00
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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更新日期：1976-07-01 00:00:00
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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pub_type： 杂志文章,评审
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journal_title：Journal of dental research
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更新日期：2009-02-01 00:00:00
abstract：:Locally applied bisphosphonates may improve the fixation of metal implants in bone. However, systemic bisphosphonate treatment is associated with a risk of osteonecrosis of the jaw (ONJ). We hypothesized that local delivery of bisphosphonate from the implant surface improves the fixation of dental implants without com...
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