Preliminary observations on the effect of mantle field radiotherapy on salivary flow rates in patients with Hodgkin's disease.

Abstract:

:Changes in stimulated and non-stimulated whole saliva flow rates were measured in 11 Hodgkin's disease patients who received therapeutic doses of radiation to a mantle field at the M. D. Anderson Hospital in Houston, Texas. Salivary flow rates were examined before, during, and after radiotherapy. Mean flow rate reductions of 54% for non-stimulated saliva and 55.7% for paraffin-stimulated saliva were observed post-radiotherapy. Flow rates had not returned to pre-irradiation levels in any of the patients who were observed for two to three months after completion of therapy. Results obtained from this preliminary study indicate that most patients who receive therapeutic doses of radiation to a mantle field experience a significant reduction in salivary output which is manifest during the period of treatment and persists for a period of at least two to three months post-radiotherapy.

journal_name

J Dent Res

authors

Bucher JA,Fleming TJ,Fuller LM,Keene HJ

doi

10.1177/00220345880670021801

keywords:

subject

Has Abstract

pub_date

1988-02-01 00:00:00

pages

518-21

issue

2

eissn

0022-0345

issn

1544-0591

journal_volume

67

pub_type

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