Evaluation of 2-phosphono-butane 1,2,4 tricarboxylate as a crystal growth inhibitor in vitro and in vivo.

abstract：:Significant differences exist between human and Macaca fascicularis patterns of mandibular movement during mastication. Macaque patterns display less asymmetry, more uniformity, and limited lateral excursions when compared to humans for mastication of the same food. Different anatomical structures between the two spec...

journal_title：Journal of dental research

authors： Byrd KE,Milberg DJ,Luschei ES

更新日期：1978-07-01 00:00:00

abstract：:Mechanical removal of oral biofilms is ubiquitously accepted as the best way to prevent caries and periodontal diseases. Removal effectiveness strongly depends on biofilm strength. To investigate the influence of hydrodynamics on oral biofilm strength, we grew single- and multi-species biofilms of Streptococcus oralis...

journal_title：Journal of dental research

authors： Paramonova E,Kalmykowa OJ,van der Mei HC,Busscher HJ,Sharma PK

更新日期：2009-10-01 00:00:00

abstract：:Apoptosis plays important roles in various stages of organogenesis. In this study, we hypothesized that apoptosis would play an important role in tooth morphogenesis. We examined the role of apoptosis in early tooth development by using a caspase inhibitor, z-VAD-fmk, concomitant with in vitro organ culture and tooth ...

journal_title：Journal of dental research

authors： Kim JY,Cha YG,Cho SW,Kim EJ,Lee MJ,Lee JM,Cai J,Ohshima H,Jung HS

更新日期：2006-06-01 00:00:00

abstract：:Ten dental casting alloys were tested for alloy-element release into cell-culture medium, and this release was related to alloy composition, alloy microstructure, and alloy cytotoxicity (previously determined). Cell-culture medium was analyzed for alloy elements by flame atomic absorption. Concentrations of elements i...

journal_title：Journal of dental research

authors： Wataha JC,Craig RG,Hanks CT

更新日期：1991-06-01 00:00:00

abstract：:In an attempt to make a dynamic study of the isoelectric point and the chargeability of human dental enamel, an electrochemical approach was utilized. Zeta potential of three kinds of the enamel was measured by a streaming potential method. As a result, these isoelectric points could be decided. ...

journal_title：Journal of dental research

authors： Kambara M,Asai T,Kumasaki M,Konishi K

更新日期：1978-02-01 00:00:00

abstract：:Cytotoxicity of fine cut amalgam was persistent until 24 hours after trituration in vitro, whereas cytotoxicity of spherical amalgam diminished more quickly. Increasing mercury content in spherical amalgam increased cytotoxicity. Possible reactions for the diminution of cytotoxicity of amalgams with time are discussed...

journal_title：Journal of dental research

authors： Kawahara H,Nakamura M,Yamagami A,Nakanishi T

更新日期：1975-03-01 00:00:00

abstract：:Previous studies showed that residual compressive stresses induced by thermal tempering retarded the growth of surface cracks in bilayered porcelain disks. The objectives of the present study were: (1) to determine whether thermal tempering by air blasting reduces the length of cracks induced by microhardness indentat...

journal_title：Journal of dental research

authors： DeHoff PH,Anusavice KJ,Vontivillu SB

更新日期：1996-02-01 00:00:00

abstract：:Previous studies suggest that salivary and pulp-derived host enzymes, matrix metalloproteinases (MMPs), may be involved in dentin caries pathogenesis. To study the inhibition of acid-activated human salivary MMPs by non-antimicrobial chemically modified tetracyclines (CMTs), we used a functional activity assay with 12...

journal_title：Journal of dental research

authors： Sulkala M,Wahlgren J,Larmas M,Sorsa T,Teronen O,Salo T,Tjäderhane L

更新日期：2001-06-01 00:00:00

abstract：:The term "artificial intelligence" (AI) refers to the idea of machines being capable of performing human tasks. A subdomain of AI is machine learning (ML), which "learns" intrinsic statistical patterns in data to eventually cast predictions on unseen data. Deep learning is a ML technique using multi-layer mathematical...

journal_title：Journal of dental research

authors： Schwendicke F,Samek W,Krois J

更新日期：2020-07-01 00:00:00

abstract：:During periods of periodontal attachment loss, one of the most significant cellular changes is a decrease in the number of fibroblasts. We previously demonstrated that LPS induces apoptosis of fibroblastic cells in vivo, largely through TNF-alpha. We conducted in vivo experiments by subcutaneous inoculation of LPS in ...

journal_title：Journal of dental research

authors： Alikhani M,Alikhani Z,Graves DT

更新日期：2004-09-01 00:00:00

abstract：:Amelogenin gene organization varies from 6 exons (1,2,3,5,6,7) in amphibians and sauropsids to 10 in rodents. The additional exons are exons 4, 8, 9, and "4b", the latter being as yet unidentified in AMELX transcripts. To learn more about the evolutionary origin of these exons, we used an in silico approach to find th...

journal_title：Journal of dental research

authors： Sire JY,Huang Y,Li W,Delgado S,Goldberg M,Denbesten PK

更新日期：2012-01-01 00:00:00

abstract：:The kinetics of growth of calcium phosphates on synthetic hydroxyapatite (HAP), human enamel, whole dentin, and human calculus has been studied at 37 C at pH values from 4.97 to 5.10 held constant by the pH-stat addition of base. Following an initial induction period, dicalcium phosphate dihydrate (DCPD) crystallizati...

journal_title：Journal of dental research

authors： Barone JP,Nancollas GH

更新日期：1978-01-01 00:00:00

abstract：:Although certain bacterial species appear to be risk factors for pain due to odontogenic infections, comparatively little is known about the potential mechanisms mediating this effect. In this study, we tested the hypothesis that trigeminal nociceptive neurons express the TLR4 or CD14 receptors, thus enabling sensory ...

journal_title：Journal of dental research

authors： Wadachi R,Hargreaves KM

更新日期：2006-01-01 00:00:00

abstract：:Previous studies show that both activin and Bmp4 act as crucial mesenchymal odontogenic signals during early tooth development. Remarkably, mice lacking activin-βA ( Inhba-/-) and mice with neural crest-specific inactivation of Bmp4 ( Bmp4ncko/ncko) both exhibit bud-stage developmental arrest of the mandibular molar t...

journal_title：Journal of dental research

authors： Kwon HE,Jia S,Lan Y,Liu H,Jiang R

更新日期：2017-09-01 00:00:00

abstract：:Streptococcus mutans produces 3 types of glucosyltransferase (GTF), whose cooperative action is considered to be essential for its cellular adherence to the tooth surface. However, the precise mechanisms for synthesizing adhesive glucans and the specific roles of each GTF in cellular adherence to smooth surfaces have ...

journal_title：Journal of dental research

authors： Ooshima T,Matsumura M,Hoshino T,Kawabata S,Sobue S,Fujiwara T

更新日期：2001-07-01 00:00:00

abstract：:Squamous cell carcinoma (SCC) of the head and neck is the sixth most frequent cancer worldwide. The survival rate is among the lowest of the major cancers and has not improved significantly in the past two decades. Extensive local invasion and regional lymph node metastasis are, in large part, responsible for the poor...

journal_title：Journal of dental research

authors： Crowe DL,Milo GE,Shuler CF

更新日期：1999-06-01 00:00:00

abstract：:The aim of this systematic review and network meta-analysis was to summarize the direct and indirect clinical evidence on the effectiveness of professionally applied and self-applied topical fluorides in preventing dental root caries. Controlled clinical trials with any follow-up duration were included. MEDLINE, PubMe...

journal_title：Journal of dental research

authors： Zhang J,Sardana D,Li KY,Leung KCM,Lo ECM

更新日期：2020-05-01 00:00:00

abstract：:Growing interest in the treatment and prevention of Molar/Incisor Hypomineralization (MIH) warrants investigation into the protein composition of hypomineralized enamel. Hypothesizing abnormality akin to amelogenesis imperfecta, we profiled proteins in hypomineralized enamel from human permanent first molars using a b...

journal_title：Journal of dental research

authors： Mangum JE,Crombie FA,Kilpatrick N,Manton DJ,Hubbard MJ

更新日期：2010-10-01 00:00:00

abstract：:Known antimalarial compunds from several chemical classes were tested for their ability to inhibit in vitro growth of microorganisms causing dental plaque and to prevent the development of plaque in a hamster model. Approximately a third of the compounds tested inhibited in vitro growth; however, none prevented develo...

journal_title：Journal of dental research

authors： Kinnamon KE,Eckermann EH,Tempel TR,Smith JH,Wolf CR

更新日期：1975-05-01 00:00:00

abstract：:The purpose of this study was to investigate the mechanism of surface layer formation in artificial white spots. Two nondestructive nuclear micro-analysis techniques were employed to analyze windows of human dental enamel at progressive stages of an artificial lesion. Fluoride concentrations were measured to a depth o...

journal_title：Journal of dental research

authors： Crawford AW,de Bruin HJ

更新日期：1983-09-01 00:00:00

abstract：:The hypothesis that periodontal disease is associated with pre-term low birthweight was tested in a prospective follow-up study of rural prima-gravida women (N = 227) who were free of tobacco, alcohol, and drug use. Women with 3rd trimester mean probing pocket depths, plaque, and bleeding scores that were greater than...

journal_title：Journal of dental research

authors： Rajapakse PS,Nagarathne M,Chandrasekra KB,Dasanayake AP

更新日期：2005-03-01 00:00:00

abstract：:Experimental marginal leakage of high- and low-Cu amalgam restorations placed in acrylic teeth, where the cavities were untreated or painted with denatured collagen and/or a CaP slurry, was assessed after specimens were stored in a 1% NaCl solution for ten days and for one yr. All specimens stored for ten days showed ...

journal_title：Journal of dental research

authors： Jodaikin A,Grossman ES

更新日期：1984-08-01 00:00:00

abstract：:Moderate elevation of serum C-reactive protein (CRP) is a risk factor for cardiovascular disease among apparently healthy individuals, although factors that create this inflammatory response in the absence of systemic illness have not been clarified. This study aimed to: (1) evaluate associations among periodontal dis...

journal_title：Journal of dental research

authors： Slade GD,Offenbacher S,Beck JD,Heiss G,Pankow JS

更新日期：2000-01-01 00:00:00

abstract：:The antimicrobial and cariostatic activities of the dihydrochloride and dihydrofluoride salts of alexidine (1,6-bis-[2-ethylhexylbiguanido]hexane) were compared to those of chlorhexidine acetate and sodium fluoride in rats implanted orally with Streptococcus mutans 6715 and fed a cariogenic diet. Experimental caries w...

journal_title：Journal of dental research

authors： Curtis SN,Dooley CL

更新日期：1979-04-01 00:00:00

abstract：:The cariostatic benefit from water fluoridation is indisputable, but the knowledge of possible adverse effects on bone and fracture risk due to fluoride exposure is ambiguous. The association between long-term (chronic) drinking water fluoride exposure and hip fracture (ICD-7-9: '820' and ICD-10: 'S72.0-S72.2') was as...

journal_title：Journal of dental research

authors： Näsman P,Ekstrand J,Granath F,Ekbom A,Fored CM

更新日期：2013-11-01 00:00:00

abstract：:The goal of this study was to assess the ability of a scintillation camera method to detect areas of active bone loss due to periodontitis. Technetium 99m methylene diphosphonate was used as the bone-seeking radiopharmaceutical. Bone-seeking radiopharmaceutical uptake (BSRU) was imaged and quantified in alveolar bone ...

journal_title：Journal of dental research

authors： Reddy MS,English R,Jeffcoat MK,Tumeh SS,Williams RC

更新日期：1991-01-01 00:00:00

abstract：:Six subjects wore intra-oral devices carrying eight bovine enamel blocks which were covered with a layer of S. mutans. They rinsed their mouths for five sec, one min, or multiples of one min with a 5 or 10% glucose (G) solution. Demineralization was measured after 45 min by determining the change in iodide permeabilit...

journal_title：Journal of dental research

authors： Tehrani A,Goulet D,Brudevold F,Attarzadeh F

更新日期：1986-02-01 00:00:00

abstract：:To determine the 'hard palate representing' area in the primary somatosensory cortex, we recorded somatosensory-evoked magnetic fields from the cortex in ten healthy volunteers, using magnetoencephalography. Following electrical stimulation of 3 sites on the hard palate (the first and third transverse palatine ridges,...

journal_title：Journal of dental research

authors： Bessho H,Shibukawa Y,Shintani M,Yajima Y,Suzuki T,Shibahara T

更新日期：2007-03-01 00:00:00

abstract：:Chronic periodontitis is a multi-factorial disease involving anaerobic bacteria and the generation of an inflammatory response, including the production of metalloproteinases, pro-inflammatory cytokines, and eicosanoids. Hypochlorous acid (HOCl) and taurine-N-monochloramine (TauCl) are the end-products of the neutroph...

journal_title：Journal of dental research

authors： Mainnemare A,Mégarbane B,Soueidan A,Daniel A,Chapple IL

更新日期：2004-11-01 00:00:00

abstract：:Submandibular glands from young adult and aged male and female rats have been examined and various descriptive parameters obtained. Several sex differences were observed with tissue from young and old animals. Sex differences were found in the gland contents of DNA, protein, and sialic acid and in some protein compone...

journal_title：Journal of dental research

authors： Kuyatt BL,Baum BJ

更新日期：1981-05-01 00:00:00