Abstract:
:Ten dental casting alloys were tested for alloy-element release into cell-culture medium, and this release was related to alloy composition, alloy microstructure, and alloy cytotoxicity (previously determined). Cell-culture medium was analyzed for alloy elements by flame atomic absorption. Concentrations of elements in the medium were normalized by dividing them by their atomic abundance in the alloy, giving element medium-alloy ratios (EMA ratios). Results showed that Au, In, and Pd generally did not dissolve into the medium, but that Ag, Cd, Cu, Ga, Ni, and Zn frequently dissolved. Comparison of EMA ratios for Ag, Cu, and Zn showed that each element retained a behavioral identity in diverse metallurgical environments, but that these environments influenced the release behavior to some degree. Some EMA ratios in multiphase alloys were greater than those in solid solutions, and EMA ratios showed great diversity within all the alloys. Nominal composition seemed to be of little value in the prediction of metal release unless the composition supported multiple-phase formation. In addition, release of alloy elements did not, in itself, completely predict alloy cytotoxicity measured previously. However, cytotoxicity was associated with metal release in each case. The commercial alloys used in this study exhibited more complex and less predictable release behavior than did the simpler ternary alloy systems used by previous investigators. It is believed that the use of commercial preparations is necessary for their in vivo behavior to be modeled.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Wataha JC,Craig RG,Hanks CTdoi
10.1177/00220345910700060301subject
Has Abstractpub_date
1991-06-01 00:00:00pages
1014-8issue
6eissn
0022-0345issn
1544-0591journal_volume
70pub_type
杂志文章abstract::Stress-induced changes imparted in a 'dentin-bonded-crown' material during sintering, annealing, pre-cementation surface modification, and resin coating have been visualized by profilometry. The hypothesis tested was that operative techniques modify the stressing pattern throughout the material thickness. We polished ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509354049
更新日期:2010-01-01 00:00:00
abstract::This study was undertaken in order to correlate the immune status of persons with various types of immune dysfunctions with the incidence of dental caries. Preliminary data on caries experience and the microbial composition of plaque in these individuals are presented. The findings suggest that persons with immunoglob...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560030201
更新日期:1977-03-01 00:00:00
abstract::Stress analyses are presented for a second mandibular premolar with a class 1 amalgam restoration. The effects of amalgam setting and thermal expansions are examined. An axisymmetric representation of the structure is used and the analyses are carried out by the finite element method. Lined and unlined restorations ar...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345780570051101
更新日期:1978-05-01 00:00:00
abstract::We determined the exposure to mercury from dental amalgam by comparison of blood levels of mercury before and after removal of all amalgams from ten subjects. Baseline concentrations of mercury in whole blood were measured weekly for four to 18 weeks (median = 6.6 weeks) prior to removal. All amalgams were removed in ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345890680050501
更新日期:1989-05-01 00:00:00
abstract::A complex feedback mechanism between parathyroid hormone (PTH), 1,25(OH)2D3 (1,25D), and fibroblast growth factor 23 (FGF-23) maintains mineral homeostasis, in part by regulating calcium and phosphate absorption/reabsorption. Previously, we showed that 1,25D regulates mineral homeostasis by repressing dentin matrix pr...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515599726
更新日期:2015-10-01 00:00:00
abstract::Fluorides are present in the environment. Excessive systemic exposure to fluorides can lead to disturbances of bone homeostasis (skeletal fluorosis) and enamel development (dental/enamel fluorosis). The severity of dental fluorosis is also dependent upon fluoride dose and the timing and duration of fluoride exposure. ...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034510384626
更新日期:2011-05-01 00:00:00
abstract::An infrared spectroscopic study has been made of the development of crystallinity (hopeite) in dental zinc phosphate cements. Crystallization in the bulk of a cement is prevented only by the incorporation, in the liquid, of aluminum which forms complexes with phosphoric acid. The development of surface crystallinity i...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345780570021801
更新日期:1978-02-01 00:00:00
abstract::Clinical studies have shown that metabolic syndrome (MetS) is associated with increased risk of developing periodontitis. However, the underlying mechanisms remain largely unknown. Since it is known that lipopolysaccharide (LPS)-activated toll-like receptor 4 signaling pathways play a crucial role in periodontitis, we...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514561658
更新日期:2015-02-01 00:00:00
abstract::The objective of this study was to calculate the stress distribution induced in anterior metal-ceramic crowns fabricated with either gold-alloy or nickel-alloy copings of reduced thickness using plane stress analyses. Two-dimensional finite element models of three crown designs were subjected to a simulated biting for...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650091201
更新日期:1986-09-01 00:00:00
abstract::Synovitis in internal derangement of the temporomandibular joint (TMJ) is accompanied by the growth of new blood vessels. Fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor (VEGF) are well-characterized angiogenic factors. The objective of this study was to elucidate the correlation between the ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200406
更新日期:2003-04-01 00:00:00
abstract::Oral bacteria, including Streptococcus mutans and Streptococcus salivarius, contribute to tooth decay and plaque formation; therefore, it is essential to develop strategies to prevent dental caries and plaque formation. We recently showed that organo-selenium compounds covalently attached to different biomaterials inh...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513482141
更新日期:2013-05-01 00:00:00
abstract::Data from the actual private practices of two dentists were compared with respective data from the participation of the same two dentists in a laboratory model of private practice conducted in the University of North Carolina Dental Research Center. The findings show that a laboratory model can be established which ac...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345750540032501
更新日期:1975-05-01 00:00:00
abstract::The tongue exerts crucial functions in our daily life. However, we know very little about the regulatory mechanisms of mammalian tongue development. In this review, we summarize recent findings of the molecular and cellular mechanisms that control tissue-tissue interactions during tongue morphogenesis. Specifically, c...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034511434055
更新日期:2012-06-01 00:00:00
abstract::The maturation of dental enamel succeeds the degradation of organic matrix. Inhibition studies have shown that this degradation is accomplished by a serine-type proteinase. To isolate and characterize cDNA clones encoding this proteinase, we used two degenerate primer approaches to amplify part of the coding region us...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345980770020601
更新日期:1998-02-01 00:00:00
abstract::Teeth to be extracted for orthodontic reasons were filled in vivo with regular and fine-cut silver amalgams containing 1% and 5% SnF2. The teeth were extracted after 15 or 30 d, and the in vivo fluoride release and uptake by the dental tissues were studied using an electron microprobe analysis technique. The obtained ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600020101
更新日期:1981-02-01 00:00:00
abstract::Obesity is a widespread chronic inflammatory disorder characterized by an increased overall disease burden and significant association with periodontitis. The aim of this prospective clinical cohort study was to investigate the effect of obesity on orthodontic tooth movement. Fifty-five adolescent patients (27 males, ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516688448
更新日期:2017-05-01 00:00:00
abstract::Secondary palatogenesis occurs when the bilateral palatal shelves (PS), arising from maxillary prominences, fuse at the midline, forming the hard and soft palate. This embryonic phenomenon involves a complex array of morphogenetic events that require coordinated proliferation, apoptosis, migration, and adhesion in the...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034517726284
更新日期:2017-10-01 00:00:00
abstract::The importance of assessing the impact of treatments for chronic conditions on an individual's quality of life has been well-established. In this randomized clinical trial, oral-health-related quality of life, measured with the Oral Health Impact Profile (OHIP), was compared between two groups of edentulous patients. ...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/00220345000790090401
更新日期:2000-09-01 00:00:00
abstract::Rat parotid atrophy, induced by liquid feeding over 10 days, was manifested as gland weight loss (40%) and histologically as acinar shrinkage. Acinar secretory function was investigated in the same glands using enzymatically dispersed cell preparations and superfused gland slices. Results were normalized for the acina...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345940730060901
更新日期:1994-06-01 00:00:00
abstract::Acculturation is a complex phenomenon that can serve as a proxy for cultural norms and behaviors affecting care-seeking, prevention behaviors, and, ultimately, health outcomes. The purpose of this study was to assess the effect of acculturation on the oral health of Haitian immigrants in New York City. We hypothesized...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910408300219
更新日期:2004-02-01 00:00:00
abstract::Although osteoporosis is a major public health concern, the effect of this condition on oral bone has not been determined. Using the ovariectomized rat as a model, we examined whether acute estrogen depletion affects the mandible of the ovariectomized rat with and without maxillary molar extraction. Twenty-two ovariec...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345940730110901
更新日期:1994-11-01 00:00:00
abstract::Resin-bonded bridges may replace missing teeth and act as splints in periodontal treatment. The objective of this study was to investigate the etch pattern after electrolytic etching of selected Co-Cr alloys in hydrochloric acid and to assess the changes in alloy composition after different etching times. The alloys i...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660091301
更新日期:1987-09-01 00:00:00
abstract::Morphogenesis (germ-tube formation) in Candida albicans was induced gratuitously by N-acetylhexosamine derivatives (N-acetyl-glucosamine covalently linked to agarose, N-acetylmannosamine, hyaluronic acid, colloidal chitin, and mucin). These compounds were not taken up by the yeast cells and did not support growth. 2-D...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630031501
更新日期:1984-03-01 00:00:00
abstract::Gingival epithelium is a site of active trafficking of Langerhans cells (LCs), while the lamina propria in chronic periodontitis (CP) contains CD83+ mature dendritic cells (mDCs) and CD4+ T-cells. The immune cells that contribute to the mDCs, and whether mDCs engage with T-cells in situ, are unclear. Using several imm...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200915
更新日期:2003-09-01 00:00:00
abstract::The dimensional accuracy of porcelain fused to metal crown and bridge castings was determined on truncated cone-shaped steel dies. Ni-Cr castings produced in manufacturers' laboratories were consistently undersize, while precious metal castings were consistently oversize. Ni-Cr castings, produced in NBS laboratories u...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580120501
更新日期:1979-12-01 00:00:00
abstract::Previous findings from studies utilizing human labial and palatine minor salivary glands are reviewed. These studies took histopathological, biochemical, and ultrastructural approaches, and focused on control and diseased glands. Disease-oriented summarization are used, and control results are discussed in the context...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660s108
更新日期:1987-02-01 00:00:00
abstract::Periodontitis is a chronic infectious disease driven by dysbiosis, an imbalance between commensal bacteria and the host organism. Periodontitis is a leading cause of tooth loss in adults and occurs in about 50% of the US population. In addition to the clinical challenges associated with treating periodontitis, the pro...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515611876
更新日期:2016-02-01 00:00:00
abstract::Excessive mechanical stress (MS) during hyperocclusion is known to result in disappearance of the alveolar hard line, enlargement of the periodontal ligament (PDL) space, and destruction of alveolar bone, leading to occlusal traumatism. We hypothesized that MS induces expression of osteoclastogenesis-associated chemok...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034511400742
更新日期:2011-06-01 00:00:00
abstract::This study demonstrated that human submandibular-sublingual saliva (HSMSL) provided a better substrate than did whole saliva or parotid saliva for the binding of Streptococcus sanguis in a glass adherence assay. Additional evidence indicated that the lower molecular weight salivary mucin in HSMSL was involved in these...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345820610120101
更新日期:1982-12-01 00:00:00
abstract::Each odontoblast is tightly linked to other odontoblasts. They form a line of defense and are capable of withstanding external stimuli, particularly the inflammation caused by caries. Thus, we investigated exosomes derived from odontoblasts as an intercellular mechanism by which inflamed odontoblasts are protected fro...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034519869580
更新日期:2019-10-01 00:00:00