Inhibition of apoptosis in early tooth development alters tooth shape and size.

abstract：:In 1984, a four-year mixed-longitudinal study of oral health was begun in Morogoro Town and Morogoro District, Tanzania. Its main goal was to detect a possible upward trend in prevalence of caries in child cohorts in this developing country. The sample consisted of 722 seven- to nine-year-olds in 1984, 833 seven- to 1...

journal_title：Journal of dental research

authors： Frencken JE,Van 't Hof MA,Truin GJ,Lembariti BS,König KG

更新日期：1989-12-01 00:00:00

abstract：:Teeth to be extracted for orthodontic reasons were filled in vivo with regular and fine-cut silver amalgams containing 1% and 5% SnF2. The teeth were extracted after 15 or 30 d, and the in vivo fluoride release and uptake by the dental tissues were studied using an electron microprobe analysis technique. The obtained ...

journal_title：Journal of dental research

authors： Souganidis DJ,Athanassouli TM,Papastathopoulos DS

更新日期：1981-02-01 00:00:00

abstract：UNLABELLED:Excessive mechanical stress (MS) during hyperocclusion is known to result in disappearance of the alveolar hard line, enlargement of the periodontal ligament (PDL) space, and destruction of alveolar bone, leading to occlusal traumatism. We have recently reported that MS induces predominantly C-C chemokine li...

journal_title：Journal of dental research

authors： Tsutsumi T,Kajiya H,Goto KT,Takahashi Y,Okabe K

更新日期：2013-01-01 00:00:00

abstract：:Wall-to-wall (WTW) polymerization contraction of filled and unfilled chemically and photo-initiated resins was studied in relation to the WTW distance. In an experimental set-up, the resins were bonded to two opposing disks, and the axial (WTW) displacement resulting from the polymerization shrinkage was measured cont...

journal_title：Journal of dental research

authors： Feilzer AJ,De Gee AJ,Davidson CL

更新日期：1989-01-01 00:00:00

abstract：:Evidence from epidemiologic studies suggests that periodontal infections are independently associated with subclinical and clinical atherosclerotic vascular disease. Although the strength of the reported associations is modest, the consistency of the data across diverse populations and a variety of exposure and outcom...

journal_title：Journal of dental research

authors： Kebschull M,Demmer RT,Papapanou PN

更新日期：2010-09-01 00:00:00

abstract：:Three strain combinations of in-bred mice representing strong and moderate histocompatibility barriers were used to determine if tooth allotransplants evoked strong or weak immunologic memory as measured by the second-set donor-strain skin graft technique. At issue was whether the anatomic site of engraftment could in...

journal_title：Journal of dental research

authors： Riviere GR

更新日期：1984-01-01 00:00:00

abstract：:Mandibular prognathism (MP) is a recognizable phenotype associated with dentoskeletal class III malocclusion. MP is a complex genetic trait, although familial recurrence also suggests the contribution of single inherited variations. To date, the genetic causes of MP have been investigated using linkage analysis or ass...

journal_title：Journal of dental research

authors： Perillo L,Monsurrò A,Bonci E,Torella A,Mutarelli M,Nigro V

更新日期：2015-04-01 00:00:00

abstract：:Early childhood caries (ECC) is a chronic disease affecting the oral health of children globally. This disease is multifactorial, but a primary factor is cariogenic microorganisms such as Streptococcus mutans. Biosynthetic gene clusters (BGCs) encode small molecules with diverse biological activities that influence th...

journal_title：Journal of dental research

authors： Momeni SS,Beno SM,Baker JL,Edlund A,Ghazal T,Childers NK,Wu H

更新日期：2020-07-01 00:00:00

abstract：:The pellicle serves as a multifunctional protective layer, providing, e.g., lubrication and remineralization and also acting as a diffusion barrier. In addition, since the formation of the pellicle precedes the adhesion of micro-organisms, it is also important as a conditioning film. We present a novel approach to stu...

journal_title：Journal of dental research

authors： Sotres J,Pettersson T,Lindh L,Arnebrant T

更新日期：2012-10-01 00:00:00

abstract：:In vitro wear data were determined for nine experimental composites and compared with two-year clinical data. The in vitro tests included single-pass wear and two-body abrasion. The in vivo data were obtained between 1978 and 1980 for 54 class 2 posterior composite restorations in 25 patients. Correlations between the...

journal_title：Journal of dental research

authors： Powers JM,Ryan MD,Hosking DJ,Goldberg AJ

更新日期：1983-10-01 00:00:00

abstract：:Conventional analyses of the cost-effectiveness of preventive regimens fail to account for the impact of attrition on reported costs. Using an economic model in which costs are allocated to fixed and variable components, and data from a recently completed clinical field trial, costs per participant are shown to vary w...

journal_title：Journal of dental research

authors： Doherty NJ

更新日期：1982-05-01 00:00:00

abstract：:Temperature elevations were measured in the pulp chamber of full cast crown preparations during impression taking with modelling compound in copper bands. Uncontrolled flaming, controlled flaming, and water heating of the bands produced temperatures of 53, 44, and 41.5 C, respectively. The time involved in restoring t...

journal_title：Journal of dental research

authors： Grajower R,Kaufman E,Stern N

更新日期：1975-03-01 00:00:00

abstract：:Bilateral resections of the superficial masseter, posterior temporal, and anterior digastric muscles of rats were done to determine their effects on mandibular growth. The macroscopic findings support the functional matrix theory of mandibular growth. The analysis of body weight and the statistical two-way analysis of...

journal_title：Journal of dental research

authors： Lifshitz J

更新日期：1976-09-01 00:00:00

abstract：:Blood cortisol levels of oral surgery patients were analyzed to objectively determine the effect of intravenous sedation on surgical stress. Results showed a measure of sedation but did not adequately reflect the stress of oral surgery or the changes produced by intravenous sedation. ...

journal_title：Journal of dental research

authors： Bunch FL,Allen GD,Jorgensen NB

更新日期：1975-09-01 00:00:00

abstract：:Although it has been shown that patients are more satisfied with prostheses supported by implants than with conventional dentures, there have been few direct comparisons of the various designs of implant-supported prostheses. This within-subject crossover clinical trial was designed to compare two forms of removable p...

journal_title：Journal of dental research

authors： Tang L,Lund JP,Taché R,Clokie CM,Feine JS

更新日期：1997-10-01 00:00:00

abstract：:Odontoblasts and fibroblasts are suspected to influence the innate immune response triggered in the dental pulp by micro-organisms that progressively invade the human tooth during the caries process. To determine whether they differ in their responses to oral pathogens, we performed a systematic comparative analysis o...

journal_title：Journal of dental research

authors： Staquet MJ,Durand SH,Colomb E,Roméas A,Vincent C,Bleicher F,Lebecque S,Farges JC

更新日期：2008-03-01 00:00:00

abstract：:The junctional epithelium (JE) is unique with regard to its wide intercellular spaces and sparsely developed intercellular junctions. Thus, knowledge of the molecular mechanisms that regulate the formation of the intercellular junctions of the junctional epithelium may be essential to understand the pathophysiology of...

journal_title：Journal of dental research

authors： Lee G,Kim HJ,Kim HM

更新日期：2016-03-01 00:00:00

abstract：:Khat-chewing has been associated with oral lesions including oral cancer, but the mechanisms leading to their development are not known. We hypothesized that khat interferes with the physiological processes of the oral mucosa, such as cell proliferation and differentiation, and aimed at investigating the effects of kh...

journal_title：Journal of dental research

authors： Lukandu OM,Neppelberg E,Vintermyr OK,Johannessen AC,Costea DE

更新日期：2010-03-01 00:00:00

abstract：:Titanium-polymethacrylate composite was prepared as an x-ray-opaque filler for composite core materials. The base monomers of the composite were 2,2-bis [4-(3-methacryloyloxy-2-hydroxypropoxy) phenyl] propane (Bis-GMA) and triethyleneglycol dimethacrylate (TEGDMA). Pure titanium powder was used as a radiopaque element...

journal_title：Journal of dental research

authors： Matsumura H,Sueyoshi M,Atsuta M

更新日期：1992-01-01 00:00:00

abstract：:The benefits of early orthodontic treatment are continuously discussed, but studies are few. We examined whether definite need for orthodontic treatment could be eliminated in public health care by systematically focusing on early intervention. One age cohort living in a rural Finnish municipality (N = 85) was regular...

journal_title：Journal of dental research

authors： Kerosuo H,Väkiparta M,Nyström M,Heikinheimo K

更新日期：2008-06-01 00:00:00

abstract：:Periodontitis is increasingly associated with increased risk of cardiovascular and other systemic diseases. The Gram-negative anaerobe, Porphyromonas gingivalis, is a key periodontal pathogen, and several lines of evidence link the presence of this bacterium in the circulation with vascular disease. The outer membrane...

journal_title：Journal of dental research

authors： Farrugia C,Stafford GP,Murdoch C

更新日期：2020-12-01 00:00:00

abstract：:The bactericidal effect of hexylresorcinol was assessed using bacterial aggregates. Increased drug concentration resulted in decreased survival of bacteria when the aggregates were exposed to hexylresorcinol for at least eight hours. This indicates that this drug may be effective against dental plaque only when availa...

journal_title：Journal of dental research

authors： Kraal JH,Hussain AA,Gregorio SB,Akaho E

更新日期：1979-11-01 00:00:00

abstract：:The human temporalis and masseter muscles are not activated homogeneously during static bite force tasks. In this study, we studied the possible existence of regional differences in these muscles under dynamic conditions. Electromyographic (EMG) activity was recorded by means of bipolar fine-wire electrodes. Six elect...

journal_title：Journal of dental research

authors： Blanksma NG,van Eijden TM

更新日期：1995-06-01 00:00:00

abstract：:The linear electrochemical polarization method was used to provide quantitative in vitro measurements of corrosion rates as a function of exposure time for Cu-Ni-Mn, Cu-Ni-Mn-Au, Cu-Ni-Mn-Ag, and Cu-Ni-Mn-Au-Ag alloys in artificial saliva. Both Au and Ag additives to dental-cast Cu-Ni-Mn alloys lowered the corrosion r...

journal_title：Journal of dental research

authors： Wright SR,Cocks FH,Gettleman L

更新日期：1980-04-01 00:00:00

abstract：:Seven ATCC strains of bacteria were examined for apatite formation in a chemically-defined calcification-supporting medium and also in a metastable calcium phosphate solution. One, E. coli, calcified in both. One, S. aureus, calcified in the solution, but not in the medium. The other five did not calcify in either. Th...

journal_title：Journal of dental research

authors： Ennever J,Streckfuss JL,Goldschmidt MC

更新日期：1981-10-01 00:00:00

abstract：:Acute or chronic inflammation comprises a highly prevalent type of orofacial pain and is mediated by the generation of endogenous agonists that activate numerous receptors expressed on terminals of trigeminal (TG) nociceptive afferent neurons. One such studied receptor is transient receptor potential vanilloid subtype...

journal_title：Journal of dental research

authors： Hargreaves KM,Ruparel S

更新日期：2016-09-01 00:00:00

abstract：:Investigators have used chemotherapeutic agents topically for plaque control without knowing the drug concentration necessary to inhibit the growth of odontopathic microorganisms. S mutans, S sanguis, A viscosus and A naeslundii are important components of the plaque flora. The minimal inhibitory concentrations (MIC) ...

journal_title：Journal of dental research

authors： Newbrun E,Felton RA,Bulkacz J

更新日期：1976-07-01 00:00:00

abstract：:Adenosine has various biological effects on human gingival fibroblasts (HGF) and epithelial cells closely associated with inflammation, such as cytokine production and cell adhesion. However, the mechanism of adenosine formation in periodontal tissues is not yet defined. In this study, we examined the involvement of C...

journal_title：Journal of dental research

authors： Hashikawa T,Takedachi M,Terakura M,Saho T,Yamada S,Thompson LF,Shimabukuro Y,Murakami S

更新日期：2003-11-01 00:00:00

abstract：:Potentially significant associations between periodontal disease and chronic kidney disease (CKD) have been reported in recent studies. The aim of this cross-sectional study was to investigate the association between serum antibody to the periodontal pathogen Porphyromonas gingivalis (P. gingivalis) and CKD in 215 Jap...

journal_title：Journal of dental research

authors： Iwasaki M,Taylor GW,Manz MC,Kaneko N,Imai S,Yoshihara A,Miyazaki H

更新日期：2012-09-01 00:00:00

abstract：:Early detection of oral premalignant lesions (OPMLs) by visual inspection with toluidine blue has not been addressed. We conducted a community-based randomized controlled trial to assess whether using toluidine blue as an adjunctive tool for visual screening had a higher detection rate of OPMLs and could further reduc...

journal_title：Journal of dental research

authors： Su WW,Yen AM,Chiu SY,Chen TH

更新日期：2010-09-01 00:00:00