Genetic association of ARHGAP21 gene variant with mandibular prognathism.

abstract：:Mutations and common polymorphisms in interferon regulatory factor 6 ( IRF6) are associated with both syndromic and nonsyndromic forms of cleft lip/palate (CLP). To date, much of the focus on this transcription factor has been on identifying its direct targets and the gene regulatory network in which it operates. Nota...

journal_title：Journal of dental research

authors： Parada-Sanchez MT,Chu EY,Cox LL,Undurty SS,Standley JM,Murray JC,Cox TC

更新日期：2017-10-01 00:00:00

abstract：:Previous studies have shown that therapeutic pulsed ultrasound (pulsed) has superior stimulatory effect on bone fracture healing compared with continuous ultrasound (continuous). Our predictive hypothesis was that pulsed ultrasound can produce better bone formation during mandibular osteodistraction than continuous ul...

journal_title：Journal of dental research

authors： El-Bialy TH,Elgazzar RF,Megahed EE,Royston TJ

更新日期：2008-10-01 00:00:00

abstract：:The role of Streptococcus mutans in the initiation of dental caries has been recognized and attributed, at least in part, to its ability to colonize the tooth surface. Therefore, factors which prevent S. mutans attachment to hydroxyapatite (HA) are of considerable interest for the prophylaxis of this infectious diseas...

journal_title：Journal of dental research

authors： Tarsi R,Muzzarelli RA,Guzmán CA,Pruzzo C

更新日期：1997-02-01 00:00:00

abstract：:The presence and kinetics of bone-resorbing activity in periapical lesions were studied with a rat model system. Lesions were found to expand most rapidly between induction on day 0 and day 15 ("active phase"), with enlargement occurring at a slower rate thereafter (days 20 and 30, "chronic phase"), as assessed by mea...

journal_title：Journal of dental research

authors： Wang CY,Stashenko P

更新日期：1991-10-01 00:00:00

abstract：:The diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection relies on the detection of viral RNA by real-time reverse transcription polymerase chain reaction (rRT-PCR) performed with respiratory specimens, especially nasopharyngeal swabs. However, this procedure requires specialized medical...

journal_title：Journal of dental research

authors： Azzi L,Maurino V,Baj A,Dani M,d'Aiuto A,Fasano M,Lualdi M,Sessa F,Alberio T

更新日期：2021-02-01 00:00:00

abstract：:The human dentition is a complex adaptive system that is influenced by genetic, epigenetic, and environmental factors. Within this system, is sexual dimorphism related to the growth promotion of the Y chromosome, or to hormonal influences, or both? This study is the first to investigate both primary and permanent toot...

journal_title：Journal of dental research

authors： Ribeiro DC,Brook AH,Hughes TE,Sampson WJ,Townsend GC

更新日期：2013-05-01 00:00:00

abstract：:Although osteoporosis is a major public health concern, the effect of this condition on oral bone has not been determined. Using the ovariectomized rat as a model, we examined whether acute estrogen depletion affects the mandible of the ovariectomized rat with and without maxillary molar extraction. Twenty-two ovariec...

journal_title：Journal of dental research

authors： Elovic RP,Hipp JA,Hayes WC

更新日期：1994-11-01 00:00:00

abstract：:Gingival overgrowth is a common side-effect of the administration of cyclosporin A (CSA), phenytoin, and calcium blockers. To identify the signaling mechanisms possibly involved in the overgrowth, we examined how CSA affects the activities of MAP kinases and transcription factors in human gingival fibroblasts (HGF). T...

journal_title：Journal of dental research

authors： Bostrom A,Bharath H,Saulewicz A,Narayanan AS

更新日期：2005-06-01 00:00:00

abstract：:The complexity of the periodontal microbiota resembles that of the gastro-intestinal tract, where infectious diseases are treatable via probiotics. In the oropharyngeal region, probiotic or replacement therapies have shown some benefit in the prevention of dental caries, otitis media, and pharyngitis, but their effect...

journal_title：Journal of dental research

authors： Teughels W,Newman MG,Coucke W,Haffajee AD,Van Der Mei HC,Haake SK,Schepers E,Cassiman JJ,Van Eldere J,van Steenberghe D,Quirynen M

更新日期：2007-11-01 00:00:00

abstract：:Van der Woude syndrome (VWS) is an autosomal-dominant oral facial disorder. To find a gene mutation in a Japanese family using fingernail DNA samples, we performed this study. We hypothesized that a gene mutation in IRF6 might be involved in VWS, and that fingernail DNA samples may be valuable for detecting such mutat...

journal_title：Journal of dental research

authors： Matsuzawa N,Shimozato K,Natsume N,Niikawa N,Yoshiura K

更新日期：2006-12-01 00:00:00

abstract：:The microstructure of the set glass-polyalkenoate cement has not been undertaken beyond a study where an Electron Probe Micro Analyser was used. The purpose of this investigation was to determine the ion distribution in matrix parts of the set cement by means of Secondary Ion Mass Spectrometry (SIMS). Among the techni...

journal_title：Journal of dental research

authors： Maeda T,Mukaeda K,Shimohira T,Katsuyama S

更新日期：1999-01-01 00:00:00

abstract：:This study's objective was to identify, in a statistically valid and efficient manner, the risk factors associated with dental implant failure. We hypothesize that factors exist which can be modified by clinicians to enhance outcome. A retrospective cohort study design was used. Cohort members had >or= one implant pla...

journal_title：Journal of dental research

authors： Chuang SK,Wei LJ,Douglass CW,Dodson TB

更新日期：2002-08-01 00:00:00

abstract：:Periodontal diseases are initiated by bacteria that accumulate in a biofilm on the tooth surface and affect the adjacent periodontal tissue. Systemic diseases such as diabetes, rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE) increase susceptibility to destructive periodontal diseases. In human studie...

journal_title：Journal of dental research

authors： Graves DT,Corrêa JD,Silva TA

更新日期：2019-02-01 00:00:00

abstract：:Adhesives cured under constrained conditions develop contraction stresses. We hypothesized that, with dentin as a bonding substrate, the stress would reach a maximum, followed by a continuous decline. Stress development was determined with a tensilometer for two total-etch systems and two systems with self-etching pri...

journal_title：Journal of dental research

authors： Hashimoto M,de Gee AJ,Kaga M,Feilzer AJ

更新日期：2006-08-01 00:00:00

abstract：:It was recently reported that human periapical cysts (hPCys), a commonly occurring odontogenic cystic lesion of inflammatory origin, contain mesenchymal stem cells (MSCs) with the capacity for self-renewal and multilineage differentiation. In this study, periapical inflammatory cysts were compared with dental pulp to ...

journal_title：Journal of dental research

authors： Marrelli M,Paduano F,Tatullo M

更新日期：2015-06-01 00:00:00

abstract：:Remineralization of demineralized dentin lesions adjacent to glass-ionomer cements (GICs) has been reported in the literature. This study tested the hypothesis that a strontium-based GIC can remineralize completely demineralized dentin by nucleation of new apatite crystallites within an apatite-free dentin matrix. Hum...

journal_title：Journal of dental research

authors： Kim YK,Yiu CK,Kim JR,Gu L,Kim SK,Weller RN,Pashley DH,Tay FR

更新日期：2010-03-01 00:00:00

abstract：:An indirect extrusion capillary viscometer has been developed. This has been tested for nonsetting Newtonian fluids and was found to give results close to, but slightly lower than the actual viscosity. The same apparatus has been successfully applied to a non-Newtonian fluid to determine the dependence of viscosity on...

journal_title：Journal of dental research

authors： Combe EC,Moser JB

更新日期：1976-03-01 00:00:00

abstract：:The type of attachment that is used in oral rehabilitation by means of implant-retained mandibular overdentures may influence the retention and the stability of the denture. In this study, we examined the hypothesis that a better retention and stability of the denture improve the oral function. Eighteen edentulous sub...

journal_title：Journal of dental research

authors： van Kampen FM,van der Bilt A,Cune MS,Bosman F

更新日期：2002-03-01 00:00:00

abstract：:Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large...

journal_title：Journal of dental research

authors： Yamada S,Ozaki N,Tsushima K,Yamaba S,Fujihara C,Awata T,Sakashita H,Kajikawa T,Kitagaki J,Yamashita M,Yanagita M,Murakami S

更新日期：2016-08-01 00:00:00

abstract：:Secondary palatogenesis occurs when the bilateral palatal shelves (PS), arising from maxillary prominences, fuse at the midline, forming the hard and soft palate. This embryonic phenomenon involves a complex array of morphogenetic events that require coordinated proliferation, apoptosis, migration, and adhesion in the...

journal_title：Journal of dental research

authors： Lough KJ,Byrd KM,Spitzer DC,Williams SE

更新日期：2017-10-01 00:00:00

abstract：:Inorganic polyphosphate [Poly(P)] is especially prevalent in osteoblasts. We tested the hypothesis that Poly(P) stimulates osteoblastic differentiation and polyphosphate metabolism for bone formation. The osteoblast-like cell line, MC 3T3-E1, was cultured with Poly(P), and gene expression was evaluated by real-time re...

journal_title：Journal of dental research

authors： Usui Y,Uematsu T,Uchihashi T,Takahashi M,Takahashi M,Ishizuka M,Doto R,Tanaka H,Komazaki Y,Osawa M,Yamada K,Yamaoka M,Furusawa K

更新日期：2010-05-01 00:00:00

abstract：:Human saliva contains a number of phosphorylated acidic proline-rich proteins (APRP). Monkey parotid saliva contains a similar protein with the same phosphorylated sequences as the human proteins. A crude protein kinase was prepared from Macaca fascicularis parotid glands which phosphorylated human APRP. The enzyme wa...

journal_title：Journal of dental research

authors： Madapallimattam G,Bennick A

更新日期：1986-03-01 00:00:00

abstract：:Due, in part, to the unique structure of the tooth, dental pain is initiated via distinct mechanisms. Here we review recent advances in our understanding of inflammatory tooth pain and discuss 3 hypotheses proposed to explain dentinal hypersensitivity: The first hypothesis, supported by functional expression of temper...

journal_title：Journal of dental research

authors： Chung G,Jung SJ,Oh SB

更新日期：2013-11-01 00:00:00

abstract：:The lack of a reliable bond test has hindered the elucidation of the mechanism for porcelain-metal bonding in dental systems, because a test capable of detecting differences among porcelain-metal bonds of various qualities is required before the reasons for these differences may be ascertained. A method was developed ...

journal_title：Journal of dental research

authors： Mackert JR Jr,Ringle RD,Parry EE,Evans AL,Fairhurst CW

更新日期：1988-02-01 00:00:00

abstract：:It is claimed that dental fluorosis in both deciduous and permanent teeth is increasing in fluoridated and non-fluoridated communities. What is unclear is whether fluoride-induced enamel opacities in the deciduous dentition are associated with the subsequent appearance of enamel defects in the permanent dentition. The...

journal_title：Journal of dental research

authors： Milsom KM,Woodward M,Haran D,Lennon MA

更新日期：1996-04-01 00:00:00

abstract：:Inferior alveolar nerve (IAN) injury induces persistent ectopic pain which spreads to a wide area in the orofacial region. Its exact mechanism remains unclear. We investigated the involvement of nitric oxide (NO) in relation to ectopic orofacial pain caused by IAN transection (IANX). We assessed the changes in mechani...

journal_title：Journal of dental research

authors： Sugiyama T,Shinoda M,Watase T,Honda K,Ito R,Kaji K,Urata K,Lee J,Ohara K,Takahashi O,Echizenya S,Iwata K

更新日期：2013-12-01 00:00:00

abstract：:The aim of this study was to compare the effectiveness of dexamethasone administration following arthrocentesis of the temporomandibular joint (TMJ) with a placebo (saline). Twenty-eight participants with TMJ arthralgia were randomly assigned to two groups of a parallel double-blind RCT. In both groups, an arthrocente...

journal_title：Journal of dental research

authors： Huddleston Slater JJ,Vos LM,Stroy LP,Stegenga B

更新日期：2012-02-01 00:00:00

abstract：:Current knowledge regarding the sensitivity of the teeth to forces is based on psychophysical experiments that measured touch detection thresholds under static jaw conditions. It is not known whether jaw movements alter the perception of forces applied to the teeth, but, based on limb movement studies, it is hypothesi...

journal_title：Journal of dental research

authors： Sowman PF,Brinkworth RS,Türker KS

更新日期：2010-04-01 00:00:00

abstract：:Not only are teeth essential for mastication, but also missing teeth are considered a social handicap due to speech and aesthetic problems, with a resulting high impact on emotional well-being. Several treatment procedures are currently available for tooth replacement with mostly inert prosthetic materials and implant...

journal_title：Journal of dental research

authors： Fleischmannova J,Matalova E,Sharpe PT,Misek I,Radlanski RJ

更新日期：2010-02-01 00:00:00

abstract：:Wall-to-wall (WTW) polymerization contraction of filled and unfilled chemically and photo-initiated resins was studied in relation to the WTW distance. In an experimental set-up, the resins were bonded to two opposing disks, and the axial (WTW) displacement resulting from the polymerization shrinkage was measured cont...

journal_title：Journal of dental research

authors： Feilzer AJ,De Gee AJ,Davidson CL

更新日期：1989-01-01 00:00:00