Failure of a glass ionomer to remineralize apatite-depleted dentin.

Abstract:

:Remineralization of demineralized dentin lesions adjacent to glass-ionomer cements (GICs) has been reported in the literature. This study tested the hypothesis that a strontium-based GIC can remineralize completely demineralized dentin by nucleation of new apatite crystallites within an apatite-free dentin matrix. Human dentin specimens were acid-etched, bonded with Fuji IX(GP), and immersed in a calcium-and-phosphate-containing 1.5X simulated body fluid (SBF) for 1-4 months. Polyacrylic acid and polyvinylphosphonic acid biomimetic analogs were added to the SBFs to create 2 additional remineralization media. Specimens were processed by transmission electron microscopy (TEM). No apatite deposition could be identified in the completely demineralized dentin in any of the specimens immersed in the 3 remineralization media, despite TEM/EDX evidence of diffusion of ions specific to the strontium-based GIC into the demineralized dentin. The hypothesis was rejected; mineral concentration alone is not a sufficient endpoint for assessing the success of contemporary remineralization strategies.

journal_name

J Dent Res

authors

Kim YK,Yiu CK,Kim JR,Gu L,Kim SK,Weller RN,Pashley DH,Tay FR

doi

10.1177/0022034509357172

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

230-5

issue

3

eissn

0022-0345

issn

1544-0591

pii

0022034509357172

journal_volume

89

pub_type

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