Role of Oxidized Lipids and TRP Channels in Orofacial Pain and Inflammation.

abstract：:Caries of the permanent first molars of 5-year-old children was found to be associated with caries of their diciduous teeth. The sample consisted of 220 children whose permanent first molars had erupted. They were selected out of 965 children who were a representative sample of children attending compulsory kindergart...

journal_title：Journal of dental research

authors： Zadik D

更新日期：1976-11-01 00:00:00

abstract：:Deciduous teeth were collected from children who received professional prophylaxis with an acidulated phosphate-fluoride (APF) or placebo paste and were analyzed to determine fluoride uptake. Enamel fluoride level was increased by the APF paste approximately 300 ppm at a depth of 2.5 micrometers during the first month...

journal_title：Journal of dental research

authors： Mellberg JR,Nicholson CR,Ripa LW,Barenie J

更新日期：1976-11-01 00:00:00

abstract：:A frameshift mutation recently identified within the paired domain of the transcription factor, PAX9, has been linked to a unique form of oligodontia in a single, multigenerational family (Stockton et al., 2000). We now describe the phenotypic and segregation analyses of this remarkable kindred, the initial approach t...

journal_title：Journal of dental research

authors： Goldenberg M,Das P,Messersmith M,Stockton DW,Patel PI,D'Souza RN

更新日期：2000-07-01 00:00:00

abstract：:Apoptosis plays important roles in various stages of organogenesis. In this study, we hypothesized that apoptosis would play an important role in tooth morphogenesis. We examined the role of apoptosis in early tooth development by using a caspase inhibitor, z-VAD-fmk, concomitant with in vitro organ culture and tooth ...

journal_title：Journal of dental research

authors： Kim JY,Cha YG,Cho SW,Kim EJ,Lee MJ,Lee JM,Cai J,Ohshima H,Jung HS

更新日期：2006-06-01 00:00:00

abstract：:Minimal invasive approaches to managing caries, such as partial caries removal techniques, are showing increasing evidence of improved outcomes over the conventional complete caries removal. There is also increasing interest in techniques where no caries is removed. We present the 1-yr results of clinical efficacy for...

journal_title：Journal of dental research

authors： Santamaria RM,Innes NP,Machiulskiene V,Evans DJ,Splieth CH

更新日期：2014-11-01 00:00:00

abstract：UNLABELLED:The aim of this observational study was to investigate the features of the chewing activity and the variability of the human chewing pace, as assessed in the natural environment. It was hypothesized that the chewing pace is relatively constant within individuals across different days but is variable across i...

journal_title：Journal of dental research

authors： Po JM,Kieser JA,Gallo LM,Tésenyi AJ,Herbison P,Farella M

更新日期：2011-10-01 00:00:00

abstract：:Experiments were performed to determine the role of the immune response in rat periodontal disease. Germ-free rats were fed defined antigen-free liquid diets or a diet containing ovalbumin(OVA) as a prototype antigen. The OVA-fed rats demonstrated increased gingival lymphocytes (mainly T at early times), OVA-sensitize...

journal_title：Journal of dental research

authors： Taubman MA,Yoshie H,Ebersole JL,Smith DJ,Olson CL

更新日期：1984-03-01 00:00:00

abstract：:The anticaries effect of professional fluoride (F) application has been attributed to calcium-fluoride-like deposits (CaF(2)) formed on enamel, but this has not been clearly demonstrated. We hypothesized that CaF(2) formed on plaque-free enamel by F application would reduce enamel demineralization due to the increase ...

journal_title：Journal of dental research

authors： Tenuta LM,Cerezetti RV,Del Bel Cury AA,Tabchoury CP,Cury JA

更新日期：2008-11-01 00:00:00

abstract：:The type of attachment that is used in oral rehabilitation by means of implant-retained mandibular overdentures may influence the retention and the stability of the denture. In this study, we examined the hypothesis that a better retention and stability of the denture improve the oral function. Eighteen edentulous sub...

journal_title：Journal of dental research

authors： van Kampen FM,van der Bilt A,Cune MS,Bosman F

更新日期：2002-03-01 00:00:00

abstract：:Adenoviral vectors effectively transfer genes to rat salivary glands. However, potent immune responses limit their use in vivo. Mice offer more opportunities than rats for the study of these immune processes. We first established conditions for infection of mouse salivary glands, with an adenoviral vector. The effects...

journal_title：Journal of dental research

authors： Wang S,Baum BJ,Yamano S,Mankani MH,Sun D,Jonsson M,Davis C,Graham FL,Gauldie J,Atkinson JC

更新日期：2000-02-01 00:00:00

abstract：:Fibroblast cultures derived from uninjured and reparative rabbit buccal mucosa were compared in terms of extracellular glycosaminoglycan (GAG) content and cellular response to interleukin-1 (IL-1). Under identical growth conditions, proliferation of both cell lines was the same. Both lines incorporated [3H]-glucosamin...

journal_title：Journal of dental research

authors： Bronson RE,Treat JA,Bertolami CN

更新日期：1989-01-01 00:00:00

abstract：:The study of biofilm structure and function mandates the use of model systems for which a host of environmental variables can be rigorously controlled. We describe a model of supragingival plaque containing Actinomyces naeslundii, Veillonella dispar, Fusobacterium nucleatum, Streptococcus sobrinus, and Streptococcus o...

journal_title：Journal of dental research

authors： Guggenheim B,Giertsen E,Schüpbach P,Shapiro S

更新日期：2001-01-01 00:00:00

abstract：:Incubation of saliva supernatant after three hours at 37 C revealed that salivary anionic proteins were susceptible to enzymatic attack by salivary enzymes not removable by centrifugation at 10,000 g. In the presence of washed suspensions of S mutans or S sanguis additional changes in electrophoretic behavior of anion...

journal_title：Journal of dental research

authors： Cowman RA,Fitzgerald RJ

更新日期：1975-03-01 00:00:00

abstract：:The sensitizing potential of three periodontal dressing materials was evaluated by the guinea pig maximization test. The results indicated a difference in the sensitization rate of the three materials. ...

journal_title：Journal of dental research

authors： Haugen E,Hensten-Pettersen A

更新日期：1978-11-01 00:00:00

abstract：:In 1992 and 1997, all US and Canadian dental schools were surveyed by mail regarding the preferred initial radiographic examination prescribed for non-emergency, comprehensive-care patients (dentulous adults, edentulous adults, and children). In both survey years, a minority of US and Canadian dental schools reported ...

journal_title：Journal of dental research

authors： Kantor ML

更新日期：2000-07-01 00:00:00

abstract：:In this study, we analyzed the influence of prosthetic abutment height on marginal bone loss (MBL) around implants in the posterior maxilla. In this retrospective cohort study, the radiographically determined MBL was related to the height of the abutments of internal conical connection implants at 6 and 18 months post...

journal_title：Journal of dental research

authors： Galindo-Moreno P,León-Cano A,Ortega-Oller I,Monje A,Suárez F,ÓValle F,Spinato S,Catena A

更新日期：2014-07-01 00:00:00

abstract：:To understand the role of betel quid (BQ) in the pathogenesis of oral submucous fibrosis (OSF) and oral cancer, we used DNA damage, cytotoxicity, and cell proliferation assays to study the pathobiological effects of aqueous extracts of three BQ constituents [betel nut (Areca catechu, BN), inflorescence of Piper betle ...

journal_title：Journal of dental research

authors： Jeng JH,Kuo ML,Hahn LJ,Kuo MY

更新日期：1994-05-01 00:00:00

abstract：:Medication-related osteonecrosis of the jaw (MRONJ), although initially believed to be exclusively associated with bisphosphonates, has been implicated in recent reports with additional drugs, especially the bone antiresorptive denosumab. The pathophysiology has not been fully elucidated, and no causal association bet...

journal_title：Journal of dental research

authors： Katsarelis H,Shah NP,Dhariwal DK,Pazianas M

更新日期：2015-04-01 00:00:00

abstract：:Samples of dental plaque obtained from the interproximal tooth surfaces of seven young men showed considerable variation in the prevalence and anatomic site distribution of the potentially cariogenic microorganism S mutans. Multiple application of 10% SnF2 topical solution and saline solution delivered to interproxima...

journal_title：Journal of dental research

authors： Keene HJ,Shklair IL,Mickel GJ

更新日期：1977-01-01 00:00:00

abstract：:Previous studies show that both activin and Bmp4 act as crucial mesenchymal odontogenic signals during early tooth development. Remarkably, mice lacking activin-βA ( Inhba-/-) and mice with neural crest-specific inactivation of Bmp4 ( Bmp4ncko/ncko) both exhibit bud-stage developmental arrest of the mandibular molar t...

journal_title：Journal of dental research

authors： Kwon HE,Jia S,Lan Y,Liu H,Jiang R

更新日期：2017-09-01 00:00:00

abstract：:This systematic review and meta-analysis assessed the efficacy of lasers in reducing dentin hypersensitivity (DH) as compared with placebo or no treatment. Seven electronic databases and a manual search resulted in 2,538 unique publications. After selection, 13 studies were included in the meta-analysis. A CONSORT-bas...

journal_title：Journal of dental research

authors： Sgolastra F,Petrucci A,Severino M,Gatto R,Monaco A

更新日期：2013-06-01 00:00:00

abstract：:Gingival overgrowth tissues have thickened connective tissue stroma, sometimes accompanied by the increased presence of collagen fibers, thickened epithelia, and elongated rete pegs. We have previously shown that expression of CCN2, also known as connective tissue growth factor (CTGF), correlates positively with the d...

journal_title：Journal of dental research

authors： Kantarci A,Nseir Z,Kim YS,Sume SS,Trackman PC

更新日期：2011-07-01 00:00:00

abstract：:Although certain bacterial species appear to be risk factors for pain due to odontogenic infections, comparatively little is known about the potential mechanisms mediating this effect. In this study, we tested the hypothesis that trigeminal nociceptive neurons express the TLR4 or CD14 receptors, thus enabling sensory ...

journal_title：Journal of dental research

authors： Wadachi R,Hargreaves KM

更新日期：2006-01-01 00:00:00

abstract：:The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts and cementoblasts. We hypothesized that stem cells may be present in the DF and be capable of differentiating into cells of the periodontium. Stem cells ...

journal_title：Journal of dental research

authors： Yao S,Pan F,Prpic V,Wise GE

更新日期：2008-08-01 00:00:00

abstract：:Alendronate (ALN) is an antiresorptive agent widely used for the treatment of osteoporosis. Its suppressive effect on osteoclasts has been extensively studied. However, the effect of ALN on bone formation is not as clear as its effect on resorption. The objective was to determine the effect of short-term ALN on bone f...

journal_title：Journal of dental research

authors： Tanoue R,Koi K,Yamashita J

更新日期：2015-09-01 00:00:00

abstract：:Stem cells from exfoliated deciduous teeth (SHED) possess multipotent differentiation and immunomodulatory properties. They have been used for orofacial bone regeneration and autoimmune disease treatment. In this study, we show that acetylsalicylic acid (ASA) treatment is able to significantly improve SHED-mediated os...

journal_title：Journal of dental research

authors： Liu Y,Chen C,Liu S,Liu D,Xu X,Chen X,Shi S

更新日期：2015-01-01 00:00:00

abstract：:Periodontitis is a chronic infectious disease driven by dysbiosis, an imbalance between commensal bacteria and the host organism. Periodontitis is a leading cause of tooth loss in adults and occurs in about 50% of the US population. In addition to the clinical challenges associated with treating periodontitis, the pro...

journal_title：Journal of dental research

authors： Martins MD,Jiao Y,Larsson L,Almeida LO,Garaicoa-Pazmino C,Le JM,Squarize CH,Inohara N,Giannobile WV,Castilho RM

更新日期：2016-02-01 00:00:00

abstract：:Hereditary diseases affecting the skeleton are heterogeneous in etiology and severity. Though many of these conditions are individually rare, the total number of people affected is great. These disorders often include dental-oral-craniofacial (DOC) manifestations, but the combination of the rarity and lack of in-depth...

journal_title：Journal of dental research

authors： Foster BL,Ramnitz MS,Gafni RI,Burke AB,Boyce AM,Lee JS,Wright JT,Akintoye SO,Somerman MJ,Collins MT

更新日期：2014-07-01 00:00:00

abstract：:Titanium-polymethacrylate composite was prepared as an x-ray-opaque filler for composite core materials. The base monomers of the composite were 2,2-bis [4-(3-methacryloyloxy-2-hydroxypropoxy) phenyl] propane (Bis-GMA) and triethyleneglycol dimethacrylate (TEGDMA). Pure titanium powder was used as a radiopaque element...

journal_title：Journal of dental research

authors： Matsumura H,Sueyoshi M,Atsuta M

更新日期：1992-01-01 00:00:00

abstract：:Bilateral resections of the superficial masseter, posterior temporal, and anterior digastric muscles of rats were done to determine their effects on mandibular growth. The macroscopic findings support the functional matrix theory of mandibular growth. The analysis of body weight and the statistical two-way analysis of...

journal_title：Journal of dental research

authors： Lifshitz J

更新日期：1976-09-01 00:00:00