Effects of oral streptococci on electrophoretic properties of human salivary anionic proteins.

abstract：:In the rat parotid acinar cell, methacholine caused an increase in [Ca2+]i as determined by quin-2 fluorescence. The increase in [Ca2+]i was initially independent of, and subsequently dependent on, the presence of extracellular Ca2+, indicating mobilization of intracellular Ca2+, as well as activation of Ca2+ entry. M...

journal_title：Journal of dental research

authors： Aub DL,Putney JW Jr

更新日期：1987-02-01 00:00:00

abstract：:Primary cilia regulate several developmental processes and mediate hedgehog signaling. To study their roles in cranial base development, we created conditional mouse mutants deficient in Polaris, a critical primary cilium component, in cartilage. Mutant post-natal cranial bases were deformed, and their synchondrosis g...

journal_title：Journal of dental research

authors： Ochiai T,Nagayama M,Nakamura T,Morrison T,Pilchak D,Kondo N,Hasegawa H,Song B,Serra R,Pacifici M,Koyama E

更新日期：2009-06-01 00:00:00

abstract：:This paper discusses loosely bound fluoride and its role in dental caries and prevention. Loosely bound fluoride (abbr. by Fa) is fluoride adsorbed onto enamel mineral crystallites. Several recent studies indicate that a high total level of fluoride in enamel does not guarantee protection against caries. This leads to...

journal_title：Journal of dental research

authors： Arends J,Christoffersen J

更新日期：1990-02-01 00:00:00

abstract：:Periodontitis is characterized by periodontal tissue destruction. Since interleukin-17 (IL-17) has been reported to up-regulate IL-1beta and tumor necrosis factor-alpha (TNF-alpha), it was hypothesized that it is increased in periodontitis and up-regulates these cytokines and tissue-destructive matrix metalloproteinas...

journal_title：Journal of dental research

authors： Beklen A,Ainola M,Hukkanen M,Gürgan C,Sorsa T,Konttinen YT

更新日期：2007-04-01 00:00:00

abstract：:Frequent consumption of cariogenic foods and bacterial infection are risk factors for early childhood caries (ECC). This study hypothesized that a short diet survey focused on frequency of foods, categorized by putative cariogenicity, would differentiate severe ECC (S-ECC) from caries-free children. Children's diets w...

journal_title：Journal of dental research

authors： Palmer CA,Kent R Jr,Loo CY,Hughes CV,Stutius E,Pradhan N,Dahlan M,Kanasi E,Arevalo Vasquez SS,Tanner AC

更新日期：2010-11-01 00:00:00

abstract：:The effect of enamel matrix proteins on the seeded growth of enamel apatite crystals was studied in stable supersaturated solutions at pH 7.4 and 37 degrees C. Of the two major protein classes in the enamel matrix, the enamelins were considerably more effective than the amelogenins in retarding seeded growth. However,...

journal_title：Journal of dental research

authors： Doi Y,Eanes ED,Shimokawa H,Termine JD

更新日期：1984-02-01 00:00:00

abstract：:Dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) are expressed as a single mRNA transcript coding for a large precursor protein termed dentin sialophosphoprotein (DSPP). DSP, DPP, and DSPP have been considered to be tooth-specific. To test for the expression of the dspp gene in bone, we performed Western immu...

journal_title：Journal of dental research

authors： Qin C,Brunn JC,Cadena E,Ridall A,Tsujigiwa H,Nagatsuka H,Nagai N,Butler WT

更新日期：2002-06-01 00:00:00

abstract：:Disks of dentin taken from extracted human teeth demonstrated the optical property of the magnification/reduction effect. When images were transmitted from a pulpal-to-occlusal direction, the images were magnified. When the disks were inverted, the images were reduced in size. The images were slightly distorted but cl...

journal_title：Journal of dental research

authors： Walton RE,Outhwaite WC,Pashley DF

更新日期：1976-07-01 00:00:00

abstract：:It has not been established whether transmission of mutans streptococci occurs between unrelated children older than 4 years of age. The aim of the study was to investigate the possible transmission of mutans streptococci genotypes from child to child in kindergarten. We studied 96 children (ages 5-6 yrs) in three San...

journal_title：Journal of dental research

authors： Doméjean S,Zhan L,DenBesten PK,Stamper J,Boyce WT,Featherstone JD

更新日期：2010-01-01 00:00:00

abstract：:Over the last hundred years, groundbreaking research in oral microbiology has provided a broad and deep understanding about the oral microbiome, its interactions with our body, and how the community can affect our health, be protective, or lead to the development of dental diseases. During this exciting journey, hypot...

journal_title：Journal of dental research

authors： Colombo APV,Tanner ACR

更新日期：2019-04-01 00:00:00

abstract：:Branching morphogenesis is essential for the formation of salivary glands, kidneys, lungs, and many other organs during development, but the mechanisms underlying this process are not adequately understood. Microarray and other gene expression methods have been powerful approaches for identifying candidate genes that ...

journal_title：Journal of dental research

authors： Hsu JC,Di Pasquale G,Harunaga JS,Onodera T,Hoffman MP,Chiorini JA,Yamada KM

更新日期：2012-02-01 00:00:00

abstract：:Seven ATCC strains of bacteria were examined for apatite formation in a chemically-defined calcification-supporting medium and also in a metastable calcium phosphate solution. One, E. coli, calcified in both. One, S. aureus, calcified in the solution, but not in the medium. The other five did not calcify in either. Th...

journal_title：Journal of dental research

authors： Ennever J,Streckfuss JL,Goldschmidt MC

更新日期：1981-10-01 00:00:00

abstract：:In a standard periodontal treatment strategy with consecutive root planings (per quadrant at a one- to two-week interval), re-infection of a disinfected area might occur before completion of the treatment. This study examines, both clinically and microbiologically, whether a full-mouth disinfection within 24 hours sig...

journal_title：Journal of dental research

authors： Quirynen M,Bollen CM,Vandekerckhove BN,Dekeyser C,Papaioannou W,Eyssen H

更新日期：1995-08-01 00:00:00

abstract：:IL-18 is a pro-inflammatory cytokine that is important in the regulation of T-cells and is elevated in inflammatory disorders such as periodontal disease. Vasoactive intestinal peptide (VIP) modulates immune responses to the periodontal pathogen Porphyromonas gingivalis (Pg). Our objective was to investigate the effec...

journal_title：Journal of dental research

authors： Foster N,Andreadou K,Jamieson L,Preshaw PM,Taylor JJ

更新日期：2007-09-01 00:00:00

abstract：:Insulin resistance is one of the critical pathogeneses of type 2 diabetes mellitus (T2DM). Elevated levels of plasma branched-chain amino acids (BCAAs) are associated with insulin resistance. Recent studies have demonstrated the role of Porphyromonas gingivalis in the development of insulin resistance. However, the me...

journal_title：Journal of dental research

authors： Tian J,Liu C,Zheng X,Jia X,Peng X,Yang R,Zhou X,Xu X

更新日期：2020-07-01 00:00:00

abstract：:The range of substrates transported by the sugar-binding protein-dependent msm (multiple sugar metabolism) system of S. mutans was investigated. By determining the ability of unlabeled sugar to compete with radiolabeled melibiose transport, we have demonstrated that the transported sugars included a number of carbohyd...

journal_title：Journal of dental research

authors： Tao L,Sutcliffe IC,Russell RR,Ferretti JJ

更新日期：1993-10-01 00:00:00

abstract：:Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large...

journal_title：Journal of dental research

authors： Yamada S,Ozaki N,Tsushima K,Yamaba S,Fujihara C,Awata T,Sakashita H,Kajikawa T,Kitagaki J,Yamashita M,Yanagita M,Murakami S

更新日期：2016-08-01 00:00:00

abstract：:Bone remodeling is a complex process regulated by several mediators. Recent work has revealed that cytokines and growth factors have significant effects on bone cell metabolism. However, little information is available concerning the production of cytokines during orthodontic tooth movement in human subjects, and ther...

journal_title：Journal of dental research

authors： Uematsu S,Mogi M,Deguchi T

更新日期：1996-01-01 00:00:00

abstract：:Vietnamese immigrant and Norwegian children, matched according to caries experience, age, and sex, were compared with respect to S. mutans in dental plaque and in saliva. Regardless of ethnic group, S. mutans prevalence was highest in plaque over caries lesions and from fissures, and lowest in plaque from smooth surfa...

journal_title：Journal of dental research

authors： Scheie AA,Selikowitz HS,Arneberg P

更新日期：1984-12-01 00:00:00

abstract：:T6 antigen is a highly specific marker for human Langerhans cells (LC). Previous studies have demonstrated that Interleukin-1 (IL-1) and an IL-1 inhibitor (ILS) modulate LC T6 expression (T6E) in explant culture. The present study examined the in vitro modulation of T6E by two molecules: epidermal-cell-derived thymocy...

journal_title：Journal of dental research

authors： Walsh LJ,Lander PE,Seymour GJ,Powell RN

更新日期：1987-03-01 00:00:00

abstract：:MMP-20 (enamelysin), the matrix metalloproteinase family member discovered in the enamel organ, has also been detected in odontoblasts during dentin formation. We studied the presence and localization of MMP-20 in mature human teeth in health and disease. In immunohistochemistry, MMP-20-positive staining was observed ...

journal_title：Journal of dental research

authors： Sulkala M,Larmas M,Sorsa T,Salo T,Tjäderhane L

更新日期：2002-09-01 00:00:00

abstract：:Periodontal inflammation and alveolar bone remodeling during orthodontic tooth movement are considered regional reactions. However, how systemic immune responses are involved in this regional reaction remains unclear. In this study, we explored the systemic effects of orthodontic force by focusing on the mononuclear p...

journal_title：Journal of dental research

authors： Zeng M,Kou X,Yang R,Liu D,Wang X,Song Y,Zhang J,Yan Y,Liu F,He D,Gan Y,Zhou Y

更新日期：2015-09-01 00:00:00

abstract：:Epstein-Barr virus (EBV), in addition to its transforming properties, contributes to the pathogenesis of several inflammatory diseases. Here, we investigated its involvement in oral lichen planus (OLP), a common autoimmune-like disease of unknown etiopathogenesis that can display a malignant potential. EBV-infected ce...

journal_title：Journal of dental research

authors： Raybaud H,Olivieri CV,Lupi-Pegurier L,Pagnotta S,Marsault R,Cardot-Leccia N,Doglio A

更新日期：2018-12-01 00:00:00

abstract：:The oral microbiome is one of the most stable ecosystems in the body and yet the reasons for this are still unclear. As well as being stable, it is also highly diverse which can be ascribed to the variety of niches available in the mouth. Previous studies have focused on the microflora in disease-either caries or peri...

journal_title：Journal of dental research

authors： Carpenter GH

更新日期：2020-06-01 00:00:00

abstract：:In periodontal surgery, healing after guided tissue regeneration (GTR) may be explained by differences in functional activities of gingival and periodontal ligament fibroblasts (GF and PDLF). Several studies in vitro have supported this hypothesis, but much remains to be defined. In the present work, gingival and peri...

journal_title：Journal of dental research

authors： Giannopoulou C,Cimasoni G

更新日期：1996-03-01 00:00:00

abstract：:Submandibular glands from young adult and aged male and female rats have been examined and various descriptive parameters obtained. Several sex differences were observed with tissue from young and old animals. Sex differences were found in the gland contents of DNA, protein, and sialic acid and in some protein compone...

journal_title：Journal of dental research

authors： Kuyatt BL,Baum BJ

更新日期：1981-05-01 00:00:00

abstract：:In 1992 and 1997, all US and Canadian dental schools were surveyed by mail regarding the preferred initial radiographic examination prescribed for non-emergency, comprehensive-care patients (dentulous adults, edentulous adults, and children). In both survey years, a minority of US and Canadian dental schools reported ...

journal_title：Journal of dental research

authors： Kantor ML

更新日期：2000-07-01 00:00:00

abstract：:Cultures of Streptococcus mutans MFe28 (serotype h) were grown with differing extracellular polysaccharide (EPS) content. Biochemical and physicochemical characteristics considered relevant to caries were measured. Acid production parameters measured in a pH-stat were: Vm = 0.76 +/- 0.14 mumol/g/sec (wet weight); appa...

journal_title：Journal of dental research

authors： Dibdin GH,Shellis RP

更新日期：1988-06-01 00:00:00

abstract：:Our observations confirm the previously reported observation that multinucleated cells develop within a two-week period in cat bone-marrow cultures. Calcitonin induces cytoplasmic contraction in these multinucleated cells, which indicates that they resemble osteoclasts. After seven days of culture, cat bone-marrow cul...

journal_title：Journal of dental research

authors： Pharoah MJ,Heersche JN

更新日期：1986-07-01 00:00:00

abstract：:The objectives of this study were 1) to provide an estimate of the value of the intraclass correlation coefficient (ICC) for dental caries data at tooth and surface level, 2) to provide an estimate of the design effect (DE) to be used in the determination of sample size estimates for future dental surveys, and 3) to e...

journal_title：Journal of dental research

authors： Masood M,Masood Y,Newton JT

更新日期：2015-02-01 00:00:00