Transport of sugars, including sucrose, by the msm transport system of Streptococcus mutans.

Abstract:

:The range of substrates transported by the sugar-binding protein-dependent msm (multiple sugar metabolism) system of S. mutans was investigated. By determining the ability of unlabeled sugar to compete with radiolabeled melibiose transport, we have demonstrated that the transported sugars included a number of carbohydrates structurally related to raffinose. A model accommodating these results has been devised which accounts for the sugars transported by the msm transport system. Competition with radiolabeled melibiose transport indicated sucrose to be an msm substrate. This was confirmed by examination of uptake of radiolabeled sucrose in scrAB mutants lacking the sucrose-specific phosphotransferase system.

journal_name

J Dent Res

authors

Tao L,Sutcliffe IC,Russell RR,Ferretti JJ

doi

10.1177/00220345930720100701

subject

Has Abstract

pub_date

1993-10-01 00:00:00

pages

1386-90

issue

10

eissn

0022-0345

issn

1544-0591

journal_volume

72

pub_type

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