MMPs, IL-1, and TNF are regulated by IL-17 in periodontitis.

abstract：:Synovial hyperplasia is a feature of degenerative temporomandibular joint (TMJ) disease. However, the mechanism by which hyperplasia progresses in the TMJ is unknown. Based on the hypothesis that the oxidative stress generated by mechanical loading causes degenerative changes in the TMJ synovium, we investigated the g...

journal_title：Journal of dental research

authors： Yamaza T,Masuda KF,Atsuta I,Nishijima K,Kido MA,Tanaka T

更新日期：2004-08-01 00:00:00

abstract：:Bisphosphonates are a class of agents used to treat osteoporosis and malignant bone metastases. The efficacy of these agents in treating and preventing the significant skeletal complications associated with these conditions has had a major positive impact for patients and is responsible for their widespread use in med...

journal_title：Journal of dental research

authors： Ruggiero SL,Drew SJ

更新日期：2007-11-01 00:00:00

abstract：:Symphyseal secondary cartilage is important for mandibular development, but the molecular mechanisms underlying its formation remain largely unknown. Here we asked whether Indian hedgehog (Ihh) regulates symphyseal cartilage development and growth. By embryonic days 16.5 to 18.5, Sox9-expressing chondrocytes formed wi...

journal_title：Journal of dental research

authors： Sugito H,Shibukawa Y,Kinumatsu T,Yasuda T,Nagayama M,Yamada S,Minugh-Purvis N,Pacifici M,Koyama E

更新日期：2011-05-01 00:00:00

abstract：:The dentition in zebrafish is extremely and richly vascularized, but the function of the vasculature, in view of the continuous replacement of the teeth, remains elusive. Through application of SU5416, a vascular endothelial growth factor receptor inhibitor, we studied the role of the blood vessels in the dentition of...

journal_title：Journal of dental research

authors： Crucke J,Huysseune A

更新日期：2015-01-01 00:00:00

abstract：:The purpose of the study was to determine the exposure times needed to harden a light-activated composite cement through various thicknesses of porcelain. A negative exponential model was developed with which the relative hardness of a composite could be predicted from the product of the exposure time and the square r...

journal_title：Journal of dental research

authors： Chan KC,Boyer DB

更新日期：1989-03-01 00:00:00

abstract：:The effect of different doses of polyadenylic and polyuridylic acids (poly A:U) was studied in control rats and in rats exposed to hypoxia. In the control rats, administration of different doses of poly A:U did not change the thickness of the epiphyseal plate or increase the incorporation of 3H-phenylalanine as judged...

journal_title：Journal of dental research

authors： Koo CS,Kim MK,Han SS

更新日期：1976-07-01 00:00:00

abstract：:The effect of enamel matrix proteins on the seeded growth of enamel apatite crystals was studied in stable supersaturated solutions at pH 7.4 and 37 degrees C. Of the two major protein classes in the enamel matrix, the enamelins were considerably more effective than the amelogenins in retarding seeded growth. However,...

journal_title：Journal of dental research

authors： Doi Y,Eanes ED,Shimokawa H,Termine JD

更新日期：1984-02-01 00:00:00

abstract：:The maturation of dental enamel succeeds the degradation of organic matrix. Inhibition studies have shown that this degradation is accomplished by a serine-type proteinase. To isolate and characterize cDNA clones encoding this proteinase, we used two degenerate primer approaches to amplify part of the coding region us...

journal_title：Journal of dental research

authors： Simmer JP,Fukae M,Tanabe T,Yamakoshi Y,Uchida T,Xue J,Margolis HC,Shimizu M,DeHart BC,Hu CC,Bartlett JD

更新日期：1998-02-01 00:00:00

abstract：:During the polymerization of multifunctional monomers for dental restorations, typical final double-bond conversions range from 55 to 75%. The low conversion results in a large amount of extractable monomer, reduced adhesion to the filler, and the potential for increased swelling. In this work, the ability to increase...

journal_title：Journal of dental research

authors： Anseth KS,Goodner MD,Reil MA,Kannurpatti AR,Newman SM,Bowman CN

更新日期：1996-08-01 00:00:00

abstract：:Wall-to-wall (WTW) polymerization contraction of filled and unfilled chemically and photo-initiated resins was studied in relation to the WTW distance. In an experimental set-up, the resins were bonded to two opposing disks, and the axial (WTW) displacement resulting from the polymerization shrinkage was measured cont...

journal_title：Journal of dental research

authors： Feilzer AJ,De Gee AJ,Davidson CL

更新日期：1989-01-01 00:00:00

abstract：:A dental appointment commonly prompts fear of a painful experience, yet we have never fully understood how our brains react to the expectation of imminent tooth pain once in a dental chair. In our study, 21 patients with hypersensitive teeth were tested using nonpainful and painful stimuli in a clinical setting. Subje...

journal_title：Journal of dental research

authors： Racek AJ,Hu X,Nascimento TD,Bender MC,Khatib L,Chiego D Jr,Holland GR,Bauer P,McDonald N,Ellwood RP,DaSilva AF

更新日期：2015-07-01 00:00:00

abstract：:Khat-chewing has been associated with oral lesions including oral cancer, but the mechanisms leading to their development are not known. We hypothesized that khat interferes with the physiological processes of the oral mucosa, such as cell proliferation and differentiation, and aimed at investigating the effects of kh...

journal_title：Journal of dental research

authors： Lukandu OM,Neppelberg E,Vintermyr OK,Johannessen AC,Costea DE

更新日期：2010-03-01 00:00:00

abstract：:We previously demonstrated that an anti-caries DNA vaccine intranasally administered with recombinant flagellin protein as a mucosal adjuvant enhanced salivary IgA response and conferred better protection against caries. However, the relatively weak immunogenicity of DNA vaccines and the necessity for a large quantity...

journal_title：Journal of dental research

authors： Sun Y,Shi W,Yang JY,Zhou DH,Chen YQ,Zhang Y,Yang Y,He BX,Zhong MH,Li YM,Cao Y,Xiao Y,Li W,Yu J,Li YH,Fan MW,Yan HM

更新日期：2012-10-01 00:00:00

abstract：:The oral microbiota was compared between Romanian adolescents with a high prevalence of caries and no dental care and Swedish caries-active and caries-free adolescents in caries prevention programs and with a low prevalence of caries. Biofilm samples were analyzed by FLX+ pyrosequencing of the V1 to V4 hypervariable r...

journal_title：Journal of dental research

authors： Johansson I,Witkowska E,Kaveh B,Lif Holgerson P,Tanner AC

更新日期：2016-01-01 00:00:00

abstract：:Pain and discomfort are common problems for patients undergoing orthodontic treatment. We have demonstrated that cortical excitation propagation in the somatosensory and insular cortices (IC) induced by electrical stimulation of the periodontal ligament (PDL) is facilitated 1 d after experimental tooth movement (ETM)....

journal_title：Journal of dental research

authors： Horinuki E,O'Hashi K,Kobayashi M

更新日期：2020-10-08 00:00:00

abstract：:Minimal invasive approaches to managing caries, such as partial caries removal techniques, are showing increasing evidence of improved outcomes over the conventional complete caries removal. There is also increasing interest in techniques where no caries is removed. We present the 1-yr results of clinical efficacy for...

journal_title：Journal of dental research

authors： Santamaria RM,Innes NP,Machiulskiene V,Evans DJ,Splieth CH

更新日期：2014-11-01 00:00:00

abstract：:Antidromic stimulation of sensory nerves has been shown to increase blood flow in the tissue they innervate. This study was designed to determine if antidromic vasomotor responses occur in feline dental pulp and if they are mediated by branched axons supplying both tooth pulp and gingiva. Dynamic changes in pulpal blo...

journal_title：Journal of dental research

authors： Sasano T,Kuriwada S,Shoji N,Sanjo D,Izumi H,Karita K

更新日期：1994-12-01 00:00:00

abstract：:Potentially significant associations between periodontal disease and chronic kidney disease (CKD) have been reported in recent studies. The aim of this cross-sectional study was to investigate the association between serum antibody to the periodontal pathogen Porphyromonas gingivalis (P. gingivalis) and CKD in 215 Jap...

journal_title：Journal of dental research

authors： Iwasaki M,Taylor GW,Manz MC,Kaneko N,Imai S,Yoshihara A,Miyazaki H

更新日期：2012-09-01 00:00:00

abstract：:Previous studies showed that residual compressive stresses induced by thermal tempering retarded the growth of surface cracks in bilayered porcelain disks. The objectives of the present study were: (1) to determine whether thermal tempering by air blasting reduces the length of cracks induced by microhardness indentat...

journal_title：Journal of dental research

authors： DeHoff PH,Anusavice KJ,Vontivillu SB

更新日期：1996-02-01 00:00:00

abstract：:The ability of physiological amounts of lysozyme to de-chain two serotype c strains of Streptococcus mutans was determined. Both human and hen lysozymes were equally effective in chain breakage of S. mutans DPR and S. mutans DJR. De-chaining did not affect growth of cultures, but resulted in finely dispersed suspensio...

journal_title：Journal of dental research

authors： Iacono VJ,Byrnes TP,Crawford IT,Grossbard BL,Pollock JJ,MacKay BJ

更新日期：1985-01-01 00:00:00

abstract：:Retinoic acid-inducible gene I (RIG-I) is a cytosolic pattern recognition receptor involved in the sensing of RNA viruses and the initiation of antiviral responses. Fusobacterium nucleatum, a Gram-negative anaerobic bacterium associated with periodontal disease, is capable of invading cells. We hypothesized that F. nu...

journal_title：Journal of dental research

authors： Lee P,Tan KS

更新日期：2014-02-01 00:00:00

abstract：:Stress-relaxation measurements were performed on specimens of radicular human dentin. The relaxation modulus showed a linear dependence on the logarithm of time and the approximation to the logarithmic distribution function of relaxation times was used to predict the behavior of other viscoelastic properties. This exp...

journal_title：Journal of dental research

authors： Duncanson MG Jr,Korostoff E

更新日期：1975-11-01 00:00:00

abstract：UNLABELLED:Dental caries affects most adults worldwide; however, the risk factors for dental caries do not necessarily exert their effects uniformly across all tooth surfaces. Instead, the actions of some risk factors may be limited to a subset of teeth/surfaces. Therefore, we used hierarchical clustering on tooth surf...

journal_title：Journal of dental research

authors： Shaffer JR,Feingold E,Wang X,Weeks DE,Weyant RJ,Crout R,McNeil DW,Marazita ML

更新日期：2013-01-01 00:00:00

abstract：:The present study investigated a concept for additional cross-linking of dental polymers, by which resistance to wear of resin composites might be increased. Bifunctional ketones were added to monomer mixtures, which were then made light-curing and loaded with filler. The monomer mixtures were varied with respect to t...

journal_title：Journal of dental research

authors： Peutzfeldt A,Asmussen E

更新日期：1992-11-01 00:00:00

abstract：:Recent studies have shown that the extent of hydrolysis by plaque of the trypsin substrate, N-benzoyl-DL-arginine-2-naphthylamide (BANA), correlates with the numbers and proportions of spirochetes in subgingival plaque samples, and appears to be an indicator of clinical disease. In this study, BANA hydrolysis by subgi...

journal_title：Journal of dental research

authors： Schmidt EF,Bretz WA,Hutchinson RA,Loesche WJ

更新日期：1988-12-01 00:00:00

abstract：:In the current theme of dental pulp regeneration, biological and synthetic scaffolds are becoming a potential therapy for pulp revitalization. The goal is to provide a suitable environment for cellular infiltration, proliferation, and differentiation. The extracellular matrix (ECM) represents a natural scaffold materi...

journal_title：Journal of dental research

authors： Alqahtani Q,Zaky SH,Patil A,Beniash E,Ray H,Sfeir C

更新日期：2018-12-01 00:00:00

abstract：:With clinical oral examinations not always possible in health surveys, researchers may instead be invited to add questions to a wider health survey. In such situations, an item is needed which adequately represents both clinical and self-reported oral health. This study investigated the clinical validity of Locker's g...

journal_title：Journal of dental research

authors： Thomson WM,Mejia GC,Broadbent JM,Poulton R

更新日期：2012-11-01 00:00:00

abstract：:This study demonstrated a correlation between silicon x-ray counts and area fractions of adherent porcelain as determined by point-counting. This correlation has allowed a method to be devised for measuring area fractions of porcelain adherent to porcelain-fused-to-metal (PFM) fracture surfaces. The described method, ...

journal_title：Journal of dental research

authors： Ringle RD,Mackert JR Jr,Fairhurst CW

更新日期：1983-08-01 00:00:00

abstract：:Smoking has been established as an important risk factor for periodontal disease and tooth loss. The purpose of this study was a prospective evaluation of the effects of smoking on dental care utilization and its costs, based on data from 5712 males aged 20-59 yrs. Age, dental health behavior, and history of diabetes ...

journal_title：Journal of dental research

authors： Ide R,Hoshuyama T,Wilson D,Takahashi K,Higashi T

更新日期：2009-01-01 00:00:00

abstract：:The eventual outcome of dental caries is determined by the dynamic balance between pathological factors that lead to demineralization and protective factors that lead to remineralization. Pathological factors include acidogenic bacteria, inhibition of salivary function, and frequency of ingestion of fermentable carboh...

journal_title：Journal of dental research

authors： Featherstone JD

更新日期：2004-01-01 00:00:00